2wl9 - Revision history

OCA at 16:01, 13 December 2023

2023-12-13T16:01:07Z

←Older revision		Revision as of 16:01, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2wl9' size='340' side='right'caption='[[2wl9]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2wl9' size='340' side='right'caption='[[2wl9]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wl9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_sp.~~_dk17~~ Rhodococcus sp. ~~dk17~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WL9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wl9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_sp._DK17 Rhodococcus sp. DK17]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WL9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MBD:3-METHYLCATECHOL'>MBD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wl3\|2wl3]]</div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MBD:3-METHYLCATECHOL'>MBD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wl9 OCA], [https://pdbe.org/2wl9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wl9 RCSB], [https://www.ebi.ac.uk/pdbsum/2wl9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wl9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wl9 OCA], [https://pdbe.org/2wl9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wl9 RCSB], [https://www.ebi.ac.uk/pdbsum/2wl9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wl9 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q6REQ5_9NOCA Q6REQ5_9NOCA]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Rhodococcus sp. ~~dk17~~]]	+	[[Category: Rhodococcus sp. DK17]]
-	[[Category: Cho~~, H J~~]]	+	[[Category: Cho HJ]]
-	[[Category: Kang~~, B S~~]]	+	[[Category: Kang BS]]
-	[[Category: Kim~~, K J]]~~	+	[[Category: Kim KJ]]
-	~~[[Category: Aromatic hydrocarbons catabolism]]~~	+
-	~~[[Category: Iron]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 11:10, 6 April 2022

2022-04-06T11:10:08Z

←Older revision		Revision as of 11:10, 6 April 2022
Line 3:		Line 3:
	<StructureSection load='2wl9' size='340' side='right'caption='[[2wl9]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2wl9' size='340' side='right'caption='[[2wl9]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wl9]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Rhodococcus_sp._dk17 Rhodococcus sp. dk17]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2WL9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wl9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_sp._dk17 Rhodococcus sp. dk17]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WL9 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MBD:3-METHYLCATECHOL'>MBD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MBD:3-METHYLCATECHOL'>MBD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wl3\|2wl3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wl3\|2wl3]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2wl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wl9 OCA], [~~http~~://pdbe.org/2wl9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wl9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wl9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wl9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wl9 OCA], [https://pdbe.org/2wl9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wl9 RCSB], [https://www.ebi.ac.uk/pdbsum/2wl9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wl9 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:52, 1 July 2020

2020-07-01T08:52:41Z

←Older revision		Revision as of 08:52, 1 July 2020
Line 1:		Line 1:

	==Crystal structure of catechol 2,3-dioxygenase==		==Crystal structure of catechol 2,3-dioxygenase==
-	<StructureSection load='2wl9' size='340' side='right' caption='[[2wl9]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='2wl9' size='340' side='right'caption='[[2wl9]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wl9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp._dk17 Rhodococcus sp. dk17]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WL9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wl9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp._dk17 Rhodococcus sp. dk17]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WL9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MBD:3-METHYLCATECHOL'>MBD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MBD:3-METHYLCATECHOL'>MBD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wl3\|2wl3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wl3\|2wl3]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wl9 OCA], [http://pdbe.org/2wl9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wl9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wl9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wl9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wl9 OCA], [http://pdbe.org/2wl9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wl9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wl9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wl9 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Dioxygenase\|Dioxygenase]]	+	*[[Dioxygenase 3D structures\|Dioxygenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Rhodococcus sp. dk17]]		[[Category: Rhodococcus sp. dk17]]
	[[Category: Cho, H J]]		[[Category: Cho, H J]]

OCA at 08:54, 26 September 2018

2018-09-26T08:54:16Z

←Older revision		Revision as of 08:54, 26 September 2018
Line 1:		Line 1:

-	==~~CRYSTAL STRUCTURE OF CATECHOL~~ 2,3-~~DIOXYGENASE~~==	+	==Crystal structure of catechol 2,3-dioxygenase==
	<StructureSection load='2wl9' size='340' side='right' caption='[[2wl9]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2wl9' size='340' side='right' caption='[[2wl9]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wl9_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wl9_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 08:59, 11 August 2016

2016-08-11T08:59:36Z

←Older revision		Revision as of 08:59, 11 August 2016
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF CATECHOL 2,3-DIOXYGENASE==		==CRYSTAL STRUCTURE OF CATECHOL 2,3-DIOXYGENASE==
	<StructureSection load='2wl9' size='340' side='right' caption='[[2wl9]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2wl9' size='340' side='right' caption='[[2wl9]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MBD:3-METHYLCATECHOL'>MBD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MBD:3-METHYLCATECHOL'>MBD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wl3\|2wl3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wl3\|2wl3]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wl9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wl9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wl9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wl9 OCA], [http://pdbe.org/2wl9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wl9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wl9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wl9 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wl9 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wl9" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 06:28, 22 January 2015

2015-01-22T06:28:38Z

←Older revision		Revision as of 06:28, 22 January 2015
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+
		+	==See Also==
		+	*[[Dioxygenase\|Dioxygenase]]
	== References ==		== References ==
	<references/>		<references/>
Line 30:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Rhodococcus sp. dk17]]		[[Category: Rhodococcus sp. dk17]]
-	[[Category: Cho, H J.]]	+	[[Category: Cho, H J]]
-	[[Category: Kang, B S.]]	+	[[Category: Kang, B S]]
-	[[Category: Kim, K J.]]	+	[[Category: Kim, K J]]
	[[Category: Aromatic hydrocarbons catabolism]]		[[Category: Aromatic hydrocarbons catabolism]]
	[[Category: Iron]]		[[Category: Iron]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 11:18, 20 October 2014

2014-10-20T11:18:35Z

←Older revision		Revision as of 11:18, 20 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2wl9.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF CATECHOL 2,3-DIOXYGENASE==
		+	<StructureSection load='2wl9' size='340' side='right' caption='[[2wl9]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wl9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp._dk17 Rhodococcus sp. dk17]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WL9 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MBD:3-METHYLCATECHOL'>MBD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wl3\|2wl3]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wl9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wl9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wl9 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wl9_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A meta-cleavage pathway for the aerobic degradation of aromatic hydrocarbons is catalyzed by extradiol dioxygenases via a two-step mechanism: catechol substrate binding and dioxygen incorporation. The binding of substrate triggers the release of water, thereby opening a coordination site for molecular oxygen. The crystal structures of AkbC, a type I extradiol dioxygenase, and the enzyme-substrate (3-methylcatechol) complex revealed the substrate-binding process of extradiol dioxygenase. AkbC is composed of an N-domain and an active C-domain, which contains iron coordinated by a 2-His-1-carboxylate facial triad motif. The C-domain includes a beta-hairpin structure and a C-terminal tail. In substrate-bound AkbC, 3-methylcatechol interacts with the iron via a single hydroxyl group, which represents an intermediate stage in the substrate-binding process. Structure-based mutagenesis revealed that the C-terminal tail and beta-hairpin form part of the substrate-binding pocket that is responsible for substrate specificity by blocking substrate entry. Once a substrate enters the active site, these structural elements also play a role in the correct positioning of the substrate. Based on the results presented here, a putative substrate-binding mechanism is proposed.

-	~~{{STRUCTURE_2wl9\| PDB=2wl9 \| SCENE= }}~~	+	Substrate-binding mechanism of a type I extradiol dioxygenase.,Cho HJ, Kim K, Sohn SY, Cho HY, Kim KJ, Kim MH, Kim D, Kim E, Kang BS J Biol Chem. 2010 Sep 1. PMID:20810655<ref>PMID:20810655</ref>

-	~~===CRYSTAL STRUCTURE OF CATECHOL 2~~,~~3-DIOXYGENASE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20810655}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2wl9]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rhodococcus_sp~~.~~_dk17 Rhodococcus sp. dk17]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020810655<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Rhodococcus sp. dk17]]		[[Category: Rhodococcus sp. dk17]]
	[[Category: Cho, H J.]]		[[Category: Cho, H J.]]

OCA: Protected "2wl9" [edit=sysop:move=sysop]

2013-01-07T19:13:07Z

Protected "2wl9" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:13, 7 January 2013

OCA at 19:13, 7 January 2013

2013-01-07T19:13:04Z

←Older revision		Revision as of 19:13, 7 January 2013
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-	{{Seed}}
	[[Image:2wl9.png\|left\|200px]]		[[Image:2wl9.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2wl9", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2wl9\| PDB=2wl9 \| SCENE= }}		{{STRUCTURE_2wl9\| PDB=2wl9 \| SCENE= }}

	===CRYSTAL STRUCTURE OF CATECHOL 2,3-DIOXYGENASE===		===CRYSTAL STRUCTURE OF CATECHOL 2,3-DIOXYGENASE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20810655}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20810655 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_20810655}}		{{ABSTRACT_PUBMED_20810655}}

	==About this Structure==		==About this Structure==
-	~~2WL9~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Rhodococcus_sp._dk17 Rhodococcus sp. dk17]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA].	+	[[2wl9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp._dk17 Rhodococcus sp. dk17]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20810655~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020810655</ref><references group="xtra"/>
	[[Category: Rhodococcus sp. dk17]]		[[Category: Rhodococcus sp. dk17]]
	[[Category: Cho, H J.]]		[[Category: Cho, H J.]]
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	[[Category: Iron]]		[[Category: Iron]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:21:49 2010''

OCA at 07:13, 15 September 2010

2010-09-15T07:13:07Z

←Older revision		Revision as of 07:13, 15 September 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:2wl9.~~jpg~~\|left\|200px]]	+	[[Image:2wl9.png\|left\|200px]]

	<!--		<!--
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	===CRYSTAL STRUCTURE OF CATECHOL 2,3-DIOXYGENASE===		===CRYSTAL STRUCTURE OF CATECHOL 2,3-DIOXYGENASE===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20810655}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20810655 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20810655}}

	==About this Structure==		==About this Structure==
	2WL9 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Rhodococcus_sp._dk17 Rhodococcus sp. dk17]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA].		2WL9 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Rhodococcus_sp._dk17 Rhodococcus sp. dk17]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WL9 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20810655</ref><references group="xtra"/>
	[[Category: Rhodococcus sp. dk17]]		[[Category: Rhodococcus sp. dk17]]
	[[Category: Cho, H J.]]		[[Category: Cho, H J.]]
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	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep ~~1 09~~:44:32 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:21:49 2010''