2wli - Revision history

OCA at 16:01, 13 December 2023

2023-12-13T16:01:22Z

←Older revision		Revision as of 16:01, 13 December 2023
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	<StructureSection load='2wli' size='340' side='right'caption='[[2wli]], [[Resolution\|resolution]] 3.09Å' scene=''>		<StructureSection load='2wli' size='340' side='right'caption='[[2wli]], [[Resolution\|resolution]] 3.09Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wli]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_31632 Atcc 31632~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WLI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wli]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WLI FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=K:POTASSIUM+ION'>K</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.09Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1xl4\|1xl4]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wlm\|2wlm]], [[1xl6\|1xl6]], [[2wlh\|2wlh]], [[2wlk\|2wlk]], [[2x6b\|2x6b]], [[2x6a\|2x6a]], [[2x6c\|2x6c]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wli OCA], [https://pdbe.org/2wli PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wli RCSB], [https://www.ebi.ac.uk/pdbsum/2wli PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wli ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wli OCA], [https://pdbe.org/2wli PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wli RCSB], [https://www.ebi.ac.uk/pdbsum/2wli PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wli ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/IRK10_MAGMG IRK10_MAGMG] Inward rectifier potassium channel that mediates potassium uptake into the cell. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification may be achieved by the blockage of outward current by cytoplasmic divalent metal ions and polyamines. Complements an E.coli mutant that is defective in K(+) uptake.<ref>PMID:20876570</ref> <ref>PMID:20564790</ref> <ref>PMID:22231399</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 31632]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Caputo, A T~~]]	+	[[Category: Magnetospirillum magnetotacticum]]
-	[[Category: ~~Clarke, O B~~]]	+	[[Category: Caputo AT]]
-	[[Category: ~~Gulbis, J M~~]]	+	[[Category: Clarke OB]]
-	[[Category: ~~Smith, B J~~]]	+	[[Category: Gulbis JM]]
-	[[Category: ~~Integral membrane protein]]~~	+	[[Category: Smith BJ]]
-	~~[[Category: Ion transport]]~~	+
-	~~[[Category: Ionic channel]]~~	+
-	~~[[Category: Metal transport]]~~	+
-	~~[[Category: Transport~~]]	+

OCA at 10:55, 7 July 2021

2021-07-07T10:55:43Z

←Older revision		Revision as of 10:55, 7 July 2021
Line 3:		Line 3:
	<StructureSection load='2wli' size='340' side='right'caption='[[2wli]], [[Resolution\|resolution]] 3.09Å' scene=''>		<StructureSection load='2wli' size='340' side='right'caption='[[2wli]], [[Resolution\|resolution]] 3.09Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wli]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WLI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wli]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WLI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wlm\|2wlm]], [[1xl6\|1xl6]], [[2wlh\|2wlh]], [[2wlk\|2wlk]], [[2x6b\|2x6b]], [[2x6a\|2x6a]], [[2x6c\|2x6c]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xl4\|1xl4]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wlm\|2wlm]], [[1xl6\|1xl6]], [[2wlh\|2wlh]], [[2wlk\|2wlk]], [[2x6b\|2x6b]], [[2x6a\|2x6a]], [[2x6c\|2x6c]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wli OCA], [~~http~~://pdbe.org/2wli PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wli RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wli PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wli ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wli OCA], [https://pdbe.org/2wli PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wli RCSB], [https://www.ebi.ac.uk/pdbsum/2wli PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wli ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Potassium ~~Channel~~\|Potassium ~~Channel~~]]	+	*[[Potassium channel 3D structures\|Potassium channel 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:25, 29 May 2019

2019-05-29T06:25:40Z

←Older revision		Revision as of 06:25, 29 May 2019
Line 1:		Line 1:

	==POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM==		==POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM==
-	<StructureSection load='2wli' size='340' side='right' caption='[[2wli]], [[Resolution\|resolution]] 3.09Å' scene=''>	+	<StructureSection load='2wli' size='340' side='right'caption='[[2wli]], [[Resolution\|resolution]] 3.09Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLI FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLI FirstGlance]. <br>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 31632]]		[[Category: Atcc 31632]]
		+	[[Category: Large Structures]]
	[[Category: Caputo, A T]]		[[Category: Caputo, A T]]
	[[Category: Clarke, O B]]		[[Category: Clarke, O B]]

OCA at 09:04, 26 September 2018

2018-09-26T09:04:55Z

←Older revision		Revision as of 09:04, 26 September 2018
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wli_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wli_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 13:28, 11 August 2016

2016-08-11T13:28:30Z

←Older revision		Revision as of 13:28, 11 August 2016
Line 1:		Line 1:
		+
	==POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM==		==POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM==
	<StructureSection load='2wli' size='340' side='right' caption='[[2wli]], [[Resolution\|resolution]] 3.09Å' scene=''>		<StructureSection load='2wli' size='340' side='right' caption='[[2wli]], [[Resolution\|resolution]] 3.09Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wlm\|2wlm]], [[1xl6\|1xl6]], [[2wlh\|2wlh]], [[2wlk\|2wlk]], [[2x6b\|2x6b]], [[2x6a\|2x6a]], [[2x6c\|2x6c]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wlm\|2wlm]], [[1xl6\|1xl6]], [[2wlh\|2wlh]], [[2wlk\|2wlk]], [[2x6b\|2x6b]], [[2x6a\|2x6a]], [[2x6c\|2x6c]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wli OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wli RCSB], [http://www.ebi.ac.uk/pdbsum/2wli PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wli OCA], [http://pdbe.org/2wli PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wli RCSB], [http://www.ebi.ac.uk/pdbsum/2wli PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wli ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wli ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wli" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Magnetospirillum magnetotacticum~~]]	+	[[Category: Atcc 31632]]
	[[Category: Caputo, A T]]		[[Category: Caputo, A T]]
	[[Category: Clarke, O B]]		[[Category: Clarke, O B]]

OCA at 11:13, 20 January 2015

2015-01-20T11:13:56Z

←Older revision		Revision as of 11:13, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLI FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLI FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wlm\|2wlm]], [[1xl6\|1xl6]], [[2wlh\|2wlh]], [[2wlk\|2wlk]], [[2x6b\|2x6b]], [[2x6a\|2x6a]], [[2x6c\|2x6c]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wlm\|2wlm]], [[1xl6\|1xl6]], [[2wlh\|2wlh]], [[2wlk\|2wlk]], [[2x6b\|2x6b]], [[2x6a\|2x6a]], [[2x6c\|2x6c]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wli OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wli RCSB], [http://www.ebi.ac.uk/pdbsum/2wli PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wli OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wli RCSB], [http://www.ebi.ac.uk/pdbsum/2wli PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Magnetospirillum magnetotacticum]]		[[Category: Magnetospirillum magnetotacticum]]
-	[[Category: Caputo, A T.]]	+	[[Category: Caputo, A T]]
-	[[Category: Clarke, O B.]]	+	[[Category: Clarke, O B]]
-	[[Category: Gulbis, J M.]]	+	[[Category: Gulbis, J M]]
-	[[Category: Smith, B J.]]	+	[[Category: Smith, B J]]
	[[Category: Integral membrane protein]]		[[Category: Integral membrane protein]]
	[[Category: Ion transport]]		[[Category: Ion transport]]

OCA at 00:59, 2 October 2014

2014-10-02T00:59:20Z

←Older revision		Revision as of 00:59, 2 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2wli.~~png~~\|~~left~~\|200px]]	+	==POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM==
		+	<StructureSection load='2wli' size='340' side='right' caption='[[2wli]], [[Resolution\|resolution]] 3.09Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLI FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wlm\|2wlm]], [[1xl6\|1xl6]], [[2wlh\|2wlh]], [[2wlk\|2wlk]], [[2x6b\|2x6b]], [[2x6a\|2x6a]], [[2x6c\|2x6c]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wli OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wli RCSB], [http://www.ebi.ac.uk/pdbsum/2wli PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wli_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Potassium channels embedded in cell membranes employ gates to regulate K+ current. While a specific constriction in the permeation pathway has historically been implicated in gating, recent reports suggest that the signature ion selectivity filter located in the outer membrane leaflet may be equally important. Inwardly rectifying K+ channels also control the directionality of flow, using intracellular polyamines to stem ion efflux by a valve-like action. This study presents crystallographic evidence of interdependent gates in the conduction pathway and reveals the mechanism of polyamine block. Reorientation of the intracellular domains, concomitant with activation, instigates polyamine release from intracellular binding sites to block the permeation pathway. Conformational adjustments of the slide helices, achieved by rotation of the cytoplasmic assembly relative to the pore, are directly correlated to the ion configuration in the selectivity filter. Ion redistribution occurs irrespective of the constriction, suggesting a more expansive role of the selectivity filter in gating than previously appreciated.

-	~~{{STRUCTURE_2wli\| PDB=2wli \| SCENE= }}~~	+	Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels.,Clarke OB, Caputo AT, Hill AP, Vandenberg JI, Smith BJ, Gulbis JM Cell. 2010 Jun 11;141(6):1018-29. PMID:20564790<ref>PMID:20564790</ref>

-	~~===POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20564790}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2wli]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA].~~	+

	==See Also==		==See Also==
	*[[Potassium Channel\|Potassium Channel]]		*[[Potassium Channel\|Potassium Channel]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020564790<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Magnetospirillum magnetotacticum]]		[[Category: Magnetospirillum magnetotacticum]]
	[[Category: Caputo, A T.]]		[[Category: Caputo, A T.]]

OCA at 15:47, 20 October 2012

2012-10-20T15:47:44Z

←Older revision		Revision as of 15:47, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2wli]] is a 2 chain structure ~~of [[Potassium Channel]]~~ with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA].	+	[[2wli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA].

	==See Also==		==See Also==

OCA: Protected "2wli" [edit=sysop:move=sysop]

2012-06-27T05:05:53Z

Protected "2wli" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:05, 27 June 2012

OCA at 05:05, 27 June 2012

2012-06-27T05:05:51Z

←Older revision		Revision as of 05:05, 27 June 2012
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-	{{Seed}}
	[[Image:2wli.png\|left\|200px]]		[[Image:2wli.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2wli", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2wli\| PDB=2wli \| SCENE= }}		{{STRUCTURE_2wli\| PDB=2wli \| SCENE= }}

	===POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM===		===POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM===

		+	{{ABSTRACT_PUBMED_20564790}}

	==About this Structure==		==About this Structure==
-	~~2WLI~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA].	+	[[2wli]] is a 2 chain structure of [[Potassium Channel]] with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLI OCA].
		+
		+	==See Also==
		+	*[[Potassium Channel\|Potassium Channel]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:020564790</ref><references group="xtra"/>
	[[Category: Magnetospirillum magnetotacticum]]		[[Category: Magnetospirillum magnetotacticum]]
	[[Category: Caputo, A T.]]		[[Category: Caputo, A T.]]
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	[[Category: Metal transport]]		[[Category: Metal transport]]
	[[Category: Transport]]		[[Category: Transport]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 23 08:40:00 2010''