2wlp - Revision history

OCA at 16:01, 13 December 2023

2023-12-13T16:01:39Z

←Older revision		Revision as of 16:01, 13 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sesbania_mosaic_virus Sesbania mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WLP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sesbania_mosaic_virus Sesbania mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WLP FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [https://pdbe.org/2wlp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [https://www.ebi.ac.uk/pdbsum/2wlp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlp ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.65Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [https://pdbe.org/2wlp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [https://www.ebi.ac.uk/pdbsum/2wlp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlp ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9EB06_9VIRU Q9EB06_9VIRU]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Sesbania mosaic virus]]		[[Category: Sesbania mosaic virus]]
-	[[Category: Anju, P]]	+	[[Category: Anju P]]
-	[[Category: Murthy~~, M R.N~~]]	+	[[Category: Murthy MRN]]
-	[[Category: Satheshkumar~~, P S~~]]	+	[[Category: Satheshkumar PS]]
-	[[Category: Savithri~~, H S~~]]	+	[[Category: Savithri HS]]
-	[[Category: Subashchandrabose, C]]	+	[[Category: Subashchandrabose C]]
-	~~[[Category: Ca2+]]~~	+
-	~~[[Category: Protein-protein interaction]]~~	+
-	~~[[Category: Viral protein]]~~	+
-	~~[[Category: Virus assembly]]~~	+
-	~~[[Category: Virus capsid]]~~	+
-	~~[[Category: Virus stability~~]]	+

OCA at 16:44, 3 November 2021

2021-11-03T16:44:14Z

←Older revision		Revision as of 16:44, 3 November 2021
Line 3:		Line 3:
	<StructureSection load='2wlp' size='340' side='right'caption='[[2wlp]], [[Resolution\|resolution]] 2.65Å' scene=''>		<StructureSection load='2wlp' size='340' side='right'caption='[[2wlp]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Sesbania_mosaic_virus Sesbania mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WLP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sesbania_mosaic_virus Sesbania mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WLP FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [~~http~~://pdbe.org/2wlp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wlp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlp ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [https://pdbe.org/2wlp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [https://www.ebi.ac.uk/pdbsum/2wlp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlp ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</div>		</div>
	<div class="pdbe-citations 2wlp" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2wlp" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:51, 21 August 2019

2019-08-21T07:51:31Z

←Older revision		Revision as of 07:51, 21 August 2019
Line 1:		Line 1:

	==Sesbania mosaic virus capsid protein dimer mutant (rCP-DEL-N65-W170K)==		==Sesbania mosaic virus capsid protein dimer mutant (rCP-DEL-N65-W170K)==
-	<StructureSection load='2wlp' size='340' side='right' caption='[[2wlp]], [[Resolution\|resolution]] 2.65Å' scene=''>	+	<StructureSection load='2wlp' size='340' side='right'caption='[[2wlp]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sesbania_mosaic_virus Sesbania mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sesbania_mosaic_virus Sesbania mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLP FirstGlance]. <br>
Line 10:		Line 10:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wlp_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wlp_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 29:		Line 29:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Sesbania mosaic virus]]		[[Category: Sesbania mosaic virus]]
	[[Category: Anju, P]]		[[Category: Anju, P]]

OCA at 07:29, 16 November 2017

2017-11-16T07:29:19Z

←Older revision		Revision as of 07:29, 16 November 2017
Line 3:		Line 3:
	<StructureSection load='2wlp' size='340' side='right' caption='[[2wlp]], [[Resolution\|resolution]] 2.65Å' scene=''>		<StructureSection load='2wlp' size='340' side='right' caption='[[2wlp]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Agati_grandiflora Agati grandiflora~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sesbania_mosaic_virus Sesbania mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLP FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [http://pdbe.org/2wlp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [http://www.ebi.ac.uk/pdbsum/2wlp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlp ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [http://pdbe.org/2wlp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [http://www.ebi.ac.uk/pdbsum/2wlp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlp ProSAT]</span></td></tr>
	</table>		</table>
Line 29:		Line 29:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Agati grandiflora~~]]	+	[[Category: Sesbania mosaic virus]]
	[[Category: Anju, P]]		[[Category: Anju, P]]
	[[Category: Murthy, M R.N]]		[[Category: Murthy, M R.N]]

OCA at 20:36, 9 December 2016

2016-12-09T20:36:10Z

←Older revision		Revision as of 20:36, 9 December 2016
Line 1:		Line 1:
		+
	==Sesbania mosaic virus capsid protein dimer mutant (rCP-DEL-N65-W170K)==		==Sesbania mosaic virus capsid protein dimer mutant (rCP-DEL-N65-W170K)==
	<StructureSection load='2wlp' size='340' side='right' caption='[[2wlp]], [[Resolution\|resolution]] 2.65Å' scene=''>		<StructureSection load='2wlp' size='340' side='right' caption='[[2wlp]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Agati_grandiflora Agati grandiflora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Agati_grandiflora Agati grandiflora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLP FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [http://www.ebi.ac.uk/pdbsum/2wlp PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [http://pdbe.org/2wlp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [http://www.ebi.ac.uk/pdbsum/2wlp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlp ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wlp ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 23:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wlp" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:23, 25 February 2015

2015-02-25T08:23:42Z

←Older revision		Revision as of 08:23, 25 February 2015
Line 2:		Line 2:
	<StructureSection load='2wlp' size='340' side='right' caption='[[2wlp]], [[Resolution\|resolution]] 2.65Å' scene=''>		<StructureSection load='2wlp' size='340' side='right' caption='[[2wlp]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sesbania_grandiflora Sesbania~~ grandiflora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Agati_grandiflora Agati grandiflora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLP FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [http://www.ebi.ac.uk/pdbsum/2wlp PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [http://www.ebi.ac.uk/pdbsum/2wlp PDBsum]</span></td></tr>
	</table>		</table>
Line 27:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Sesbania~~ grandiflora]]	+	[[Category: Agati grandiflora]]
	[[Category: Anju, P]]		[[Category: Anju, P]]
	[[Category: Murthy, M R.N]]		[[Category: Murthy, M R.N]]

OCA at 11:54, 20 January 2015

2015-01-20T11:54:43Z

←Older revision		Revision as of 11:54, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sesbania_grandiflora Sesbania grandiflora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sesbania_grandiflora Sesbania grandiflora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLP FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [http://www.ebi.ac.uk/pdbsum/2wlp PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [http://www.ebi.ac.uk/pdbsum/2wlp PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Sesbania grandiflora]]		[[Category: Sesbania grandiflora]]
-	[[Category: Anju, P.]]	+	[[Category: Anju, P]]
-	[[Category: Murthy, M R.N.]]	+	[[Category: Murthy, M R.N]]
-	[[Category: Satheshkumar, P S.]]	+	[[Category: Satheshkumar, P S]]
-	[[Category: Savithri, H S.]]	+	[[Category: Savithri, H S]]
-	[[Category: Subashchandrabose, C.]]	+	[[Category: Subashchandrabose, C]]
	[[Category: Ca2+]]		[[Category: Ca2+]]
	[[Category: Protein-protein interaction]]		[[Category: Protein-protein interaction]]

OCA at 04:30, 3 October 2014

2014-10-03T04:30:18Z

←Older revision		Revision as of 04:30, 3 October 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2wlp\| PDB=2wlp \| SCENE= }}~~	+	==Sesbania mosaic virus capsid protein dimer mutant (rCP-DEL-N65-W170K)==
-	===Sesbania mosaic virus capsid protein dimer mutant (rCP-DEL-N65-W170K)===	+	<StructureSection load='2wlp' size='340' side='right' caption='[[2wlp]], [[Resolution\|resolution]] 2.65Å' scene=''>
-	~~{{ABSTRACT_PUBMED_19643453}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sesbania_grandiflora Sesbania grandiflora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLP FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wlp RCSB], [http://www.ebi.ac.uk/pdbsum/2wlp PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wlp_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protein-protein interactions play a crucial role in virus assembly and stability. With the view of disrupting capsid assembly and capturing smaller oligomers, interfacial residue mutations were carried out in the coat protein gene of Sesbania Mosaic Virus, a T=3 ss (+) RNA plant virus. A single point mutation of a Trp 170 present at the five-fold interface of the virus to a charged residue (Glu or Lys) arrested assembly of virus like particles and resulted in stable soluble dimers of the capsid protein. The X-ray crystal structure of one of the isolated dimer mutants - rCPDeltaN65W170K was determined to a resolution of 2.65 A. Detailed analysis of the dimeric mutant protein structure revealed that a number of structural changes take place, especially in the loop and interfacial regions during the course of assembly. The isolated dimer was "more relaxed" than the dimer found in the T=3 or T=1 capsids. The isolated dimer does not bind Ca(2+) ion and consequently four C-terminal residues are disordered. The FG loop, which interacts with RNA in the virus, has different conformations in the isolated dimer and the intact virus suggesting its flexible nature and the conformational changes that accompany assembly. The isolated dimer mutant was much less stable when compared to the assembled capsids, suggesting the importance of inter-subunit interactions and Ca(2+) mediated interactions in the stability of the capsids. With this study, SeMV becomes the first icosahedral virus for which X-ray crystal structures of T=3, T=1 capsids as well as a smaller oligomer of the capsid protein have been determined.

-	~~==About this Structure==~~	+	A single point mutation disrupts the capsid assembly in Sesbania Mosaic Virus resulting in a stable isolated dimer.,Pappachan A, Chinnathambi S, Satheshkumar PS, Savithri HS, Murthy MR Virology. 2009 Sep 30;392(2):215-21. doi: 10.1016/j.virol.2009.06.047. Epub 2009 , Jul 30. PMID:19643453<ref>PMID:19643453</ref>
-	~~[[2wlp]] is~~ a 2 ~~chain structure with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki~~/~~Sesbania_grandiflora Sesbania grandiflora]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id~~=~~2WLP OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Sesbania grandiflora]]		[[Category: Sesbania grandiflora]]
	[[Category: Anju, P.]]		[[Category: Anju, P.]]

OCA at 19:31, 17 April 2013

2013-04-17T19:31:20Z

←Older revision		Revision as of 19:31, 17 April 2013
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	{{STRUCTURE_2wlp\| PDB=2wlp \| SCENE= }}		{{STRUCTURE_2wlp\| PDB=2wlp \| SCENE= }}
-	===~~SESBANIA MOSAIC VIRUS CAPSID PROTEIN DIMER MUTANT~~ (~~RCP~~-DEL-N65-W170K)===	+	===Sesbania mosaic virus capsid protein dimer mutant (rCP-DEL-N65-W170K)===
		+	{{ABSTRACT_PUBMED_19643453}}

	==About this Structure==		==About this Structure==

OCA at 09:43, 27 March 2013

2013-03-27T09:43:47Z

←Older revision		Revision as of 09:43, 27 March 2013
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-	[[Image:2wlp.png\|left\|200px]]
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	{{STRUCTURE_2wlp\| PDB=2wlp \| SCENE= }}		{{STRUCTURE_2wlp\| PDB=2wlp \| SCENE= }}
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	===SESBANIA MOSAIC VIRUS CAPSID PROTEIN DIMER MUTANT (RCP-DEL-N65-W170K)===		===SESBANIA MOSAIC VIRUS CAPSID PROTEIN DIMER MUTANT (RCP-DEL-N65-W170K)===
-

	==About this Structure==		==About this Structure==