2wne - Revision history

OCA at 10:56, 7 July 2021

2021-07-07T10:56:47Z

←Older revision		Revision as of 10:56, 7 July 2021
Line 3:		Line 3:
	<StructureSection load='2wne' size='340' side='right'caption='[[2wne]], [[Resolution\|resolution]] 2.12Å' scene=''>		<StructureSection load='2wne' size='340' side='right'caption='[[2wne]], [[Resolution\|resolution]] 2.12Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wne]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Chrysosporium_pruinosum_(gilman_&_abbott)_carmich. Chrysosporium pruinosum (gilman & abbott) carmich.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WNE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wne]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chrysosporium_pruinosum_(gilman_&_abbott)_carmich. Chrysosporium pruinosum (gilman & abbott) carmich.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WNE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wlq\|2wlq]], [[2w39\|2w39]], [[2w52\|2w52]], [[2cl2\|2cl2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wlq\|2wlq]], [[2w39\|2w39]], [[2w52\|2w52]], [[2cl2\|2cl2]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Endo-1,3(4)-beta-glucanase Endo-1,3(4)-beta-glucanase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.6 3.2.1.6] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endo-1,3(4)-beta-glucanase Endo-1,3(4)-beta-glucanase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.6 3.2.1.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wne OCA], [~~http~~://pdbe.org/2wne PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wne RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wne PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wne ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wne OCA], [https://pdbe.org/2wne PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wne RCSB], [https://www.ebi.ac.uk/pdbsum/2wne PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wne ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 12:19, 10 May 2019

2019-05-10T12:19:22Z

←Older revision		Revision as of 12:19, 10 May 2019
Line 1:		Line 1:

	==Mutant Laminarinase 16A cyclizes laminariheptaose==		==Mutant Laminarinase 16A cyclizes laminariheptaose==
-	<StructureSection load='2wne' size='340' side='right' caption='[[2wne]], [[Resolution\|resolution]] 2.12Å' scene=''>	+	<StructureSection load='2wne' size='340' side='right'caption='[[2wne]], [[Resolution\|resolution]] 2.12Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wne]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chrysosporium_pruinosum_(gilman_&_abbott)_carmich. Chrysosporium pruinosum (gilman & abbott) carmich.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wne]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chrysosporium_pruinosum_(gilman_&_abbott)_carmich. Chrysosporium pruinosum (gilman & abbott) carmich.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNE FirstGlance]. <br>
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Andersson, E]]		[[Category: Andersson, E]]
	[[Category: Einarsson, E]]		[[Category: Einarsson, E]]

OCA at 09:37, 26 September 2018

2018-09-26T09:37:37Z

←Older revision		Revision as of 09:37, 26 September 2018
Line 1:		Line 1:
-	==~~MUTANT LAMINARINASE~~ 16A ~~CYCLIZES LAMINARIHEPTAOSE~~==	+
		+	==Mutant Laminarinase 16A cyclizes laminariheptaose==
	<StructureSection load='2wne' size='340' side='right' caption='[[2wne]], [[Resolution\|resolution]] 2.12Å' scene=''>		<StructureSection load='2wne' size='340' side='right' caption='[[2wne]], [[Resolution\|resolution]] 2.12Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wlq\|2wlq]], [[2w39\|2w39]], [[2w52\|2w52]], [[2cl2\|2cl2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wlq\|2wlq]], [[2w39\|2w39]], [[2w52\|2w52]], [[2cl2\|2cl2]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,3(4)-beta-glucanase Endo-1,3(4)-beta-glucanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.6 3.2.1.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,3(4)-beta-glucanase Endo-1,3(4)-beta-glucanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.6 3.2.1.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wne OCA], [http://pdbe.org/2wne PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wne RCSB], [http://www.ebi.ac.uk/pdbsum/2wne PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wne OCA], [http://pdbe.org/2wne PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wne RCSB], [http://www.ebi.ac.uk/pdbsum/2wne PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wne ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wne_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wne_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 17:23, 8 February 2016

2016-02-08T17:23:36Z

←Older revision		Revision as of 17:23, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='2wne' size='340' side='right' caption='[[2wne]], [[Resolution\|resolution]] 2.12Å' scene=''>		<StructureSection load='2wne' size='340' side='right' caption='[[2wne]], [[Resolution\|resolution]] 2.12Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wne]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Phanerochaete_chrysosporium Phanerochaete chrysosporium~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wne]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chrysosporium_pruinosum_(gilman_&_abbott)_carmich. Chrysosporium pruinosum (gilman & abbott) carmich.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wlq\|2wlq]], [[2w39\|2w39]], [[2w52\|2w52]], [[2cl2\|2cl2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wlq\|2wlq]], [[2w39\|2w39]], [[2w52\|2w52]], [[2cl2\|2cl2]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,3(4)-beta-glucanase Endo-1,3(4)-beta-glucanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.6 3.2.1.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,3(4)-beta-glucanase Endo-1,3(4)-beta-glucanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.6 3.2.1.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wne OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wne RCSB], [http://www.ebi.ac.uk/pdbsum/2wne PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wne OCA], [http://pdbe.org/2wne PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wne RCSB], [http://www.ebi.ac.uk/pdbsum/2wne PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wne ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wne" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Phanerochaete chrysosporium]]
	[[Category: Andersson, E]]		[[Category: Andersson, E]]
	[[Category: Einarsson, E]]		[[Category: Einarsson, E]]

OCA at 08:33, 20 January 2015

2015-01-20T08:33:23Z

←Older revision		Revision as of 08:33, 20 January 2015
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Phanerochaete chrysosporium]]		[[Category: Phanerochaete chrysosporium]]
-	[[Category: Andersson, E.]]	+	[[Category: Andersson, E]]
-	[[Category: Einarsson, E.]]	+	[[Category: Einarsson, E]]
-	[[Category: Engstrom, A.]]	+	[[Category: Engstrom, A]]
-	[[Category: Forsberg, Z.]]	+	[[Category: Forsberg, Z]]
-	[[Category: Hansson, H.]]	+	[[Category: Hansson, H]]
-	[[Category: Igarashi, K.]]	+	[[Category: Igarashi, K]]
-	[[Category: Jonsson, K H.M.]]	+	[[Category: Jonsson, K H.M]]
-	[[Category: Kawai, R.]]	+	[[Category: Kawai, R]]
-	[[Category: Samejima, M.]]	+	[[Category: Samejima, M]]
-	[[Category: Sandgren, M.]]	+	[[Category: Sandgren, M]]
-	[[Category: Stahlberg, J.]]	+	[[Category: Stahlberg, J]]
-	[[Category: Vasur, J.]]	+	[[Category: Vasur, J]]
-	[[Category: Widmalm, G.]]	+	[[Category: Widmalm, G]]
	[[Category: 6-glucan]]		[[Category: 6-glucan]]
	[[Category: Basidiomycete]]		[[Category: Basidiomycete]]

OCA at 06:12, 10 October 2014

2014-10-10T06:12:18Z

←Older revision		Revision as of 06:12, 10 October 2014
Line 2:		Line 2:
	<StructureSection load='2wne' size='340' side='right' caption='[[2wne]], [[Resolution\|resolution]] 2.12Å' scene=''>		<StructureSection load='2wne' size='340' side='right' caption='[[2wne]], [[Resolution\|resolution]] 2.12Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wne]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phanerochaete_chrysosporium Phanerochaete chrysosporium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA]. <br>	+	<table><tr><td colspan='2'>[[2wne]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phanerochaete_chrysosporium Phanerochaete chrysosporium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNE FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wlq\|2wlq]], [[2w39\|2w39]], [[2w52\|2w52]], [[2cl2\|2cl2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wlq\|2wlq]], [[2w39\|2w39]], [[2w52\|2w52]], [[2cl2\|2cl2]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Glucokinase Glucokinase~~], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,3(4)-beta-glucanase Endo-1,3(4)-beta-glucanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.6 3.2.1.6] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wne OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wne RCSB], [http://www.ebi.ac.uk/pdbsum/2wne PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wne OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wne RCSB], [http://www.ebi.ac.uk/pdbsum/2wne PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 24:
	Synthesis of Cyclic beta-Glucan Using Laminarinase 16A Glycosynthase Mutant from the Basidiomycete Phanerochaete chrysosporium.,Vasur J, Kawai R, Jonsson KH, Widmalm G, Engstrom A, Frank M, Andersson E, Hansson H, Forsberg Z, Igarashi K, Samejima M, Sandgren M, Stahlberg J J Am Chem Soc. 2010 Jan 15. PMID:20078120<ref>PMID:20078120</ref>		Synthesis of Cyclic beta-Glucan Using Laminarinase 16A Glycosynthase Mutant from the Basidiomycete Phanerochaete chrysosporium.,Vasur J, Kawai R, Jonsson KH, Widmalm G, Engstrom A, Frank M, Andersson E, Hansson H, Forsberg Z, Igarashi K, Samejima M, Sandgren M, Stahlberg J J Am Chem Soc. 2010 Jan 15. PMID:20078120<ref>PMID:20078120</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==

OCA at 08:39, 7 May 2014

2014-05-07T08:39:31Z

←Older revision		Revision as of 08:39, 7 May 2014
Line 1:		Line 1:
-	[[~~Image:~~2wne.~~png~~\|~~left~~\|200px]]	+	==MUTANT LAMINARINASE 16A CYCLIZES LAMINARIHEPTAOSE==
		+	<StructureSection load='2wne' size='340' side='right' caption='[[2wne]], [[Resolution\|resolution]] 2.12Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wne]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phanerochaete_chrysosporium Phanerochaete chrysosporium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wlq\|2wlq]], [[2w39\|2w39]], [[2w52\|2w52]], [[2cl2\|2cl2]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wne OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wne RCSB], [http://www.ebi.ac.uk/pdbsum/2wne PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wne_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glycosynthases are precise molecular instruments for making specifically linked oligosaccharides. X-ray crystallography screening of ligands bound to the 1,3(4)-beta-d-glucanase nucleophile mutant E115S of Phanerochaete chrysosporium Laminarinase 16A (Lam16A) showed that laminariheptaose (L7) bound in an arch with the reducing and nonreducing ends occupying either side of the catalytic cleft of the enzyme. The X-ray structure of Lam16A E115S in complex with alpha-laminariheptaosyl fluoride (alphaL7F) revealed how alphaL7F could make a nucleophilic attack upon itself. Indeed, when Lam16A E115S was allowed to react with alphaL7F the major product was a cyclic beta-1,3-heptaglucan, as shown by mass spectrometry. NMR confirmed uniquely beta-1,3-linkages and no reducing end. Molecular dynamics simulations indicate that the cyclic laminariheptaose molecule is not completely planar and that torsion angles at the glycosidic linkages fluctuate between two energy minima. This is the first report of a glycosynthase that joins the reducing and nonreducing ends of a single oligosaccharide and the first reported synthesis of cyclic beta-glucan.

-	~~<!-~~-	+	Synthesis of Cyclic beta-Glucan Using Laminarinase 16A Glycosynthase Mutant from the Basidiomycete Phanerochaete chrysosporium.,Vasur J, Kawai R, Jonsson KH, Widmalm G, Engstrom A, Frank M, Andersson E, Hansson H, Forsberg Z, Igarashi K, Samejima M, Sandgren M, Stahlberg J J Am Chem Soc. 2010 Jan 15. PMID:20078120<ref>PMID:20078120</ref>
-	~~The line below this paragraph, containing "STRUCTURE_2wne", creates~~ the ~~"Structure Box" on the page~~.	+
-	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded)~~,	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2wne\| PDB=2wne \| SCENE= }}~~	+

-	~~===MUTANT LAMINARINASE 16A CYCLIZES LAMINARIHEPTAOSE===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_20078120}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 20078120 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_20078120}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2wne]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Phanerochaete_chrysosporium Phanerochaete chrysosporium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020078120<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Phanerochaete chrysosporium]]		[[Category: Phanerochaete chrysosporium]]
	[[Category: Andersson, E.]]		[[Category: Andersson, E.]]

OCA: Protected "2wne" [edit=sysop:move=sysop]

2011-09-21T04:59:48Z

Protected "2wne" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:59, 21 September 2011

OCA at 04:59, 21 September 2011

2011-09-21T04:59:46Z

←Older revision		Revision as of 04:59, 21 September 2011
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:2wne.png\|left\|200px]]
-	[[Image:2wne.~~jpg~~\|left\|200px]]	+

	<!--		<!--
Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~2WNE~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phanerochaete_chrysosporium Phanerochaete chrysosporium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA].	+	[[2wne]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phanerochaete_chrysosporium Phanerochaete chrysosporium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20078120~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020078120</ref><references group="xtra"/>
	[[Category: Phanerochaete chrysosporium]]		[[Category: Phanerochaete chrysosporium]]
	[[Category: Andersson, E.]]		[[Category: Andersson, E.]]
Line 51:		Line 50:
	[[Category: Lam16a]]		[[Category: Lam16a]]
	[[Category: Laminarin]]		[[Category: Laminarin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:32:18 2010''

OCA at 17:32, 27 January 2010

2010-01-27T17:32:20Z

←Older revision		Revision as of 17:32, 27 January 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:2wne.jpg\|left\|200px]]

-	The ~~entry 2wne~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2wne", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2wne\| PDB=2wne \| SCENE= }}

-	~~Authors: Vasur, J., Kawai, R., Andersson, E., Widmalm, G., Jonsson, K.H.M., Hansson, H., Engstrom, A., Einarsson, E., Forsberg, Z., Igarashi, K., Sandgren, M., Samejima, M., Stahlberg, J.~~	+	===MUTANT LAMINARINASE 16A CYCLIZES LAMINARIHEPTAOSE===

-	Description: Mutant Laminarinase 16A cyclizes laminariheptaose

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Aug 5 09~~:32:~~47 2009~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20078120}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20078120 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20078120}}
		+
		+	==About this Structure==
		+	2WNE is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Phanerochaete_chrysosporium Phanerochaete chrysosporium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNE OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20078120</ref><references group="xtra"/>
		+	[[Category: Phanerochaete chrysosporium]]
		+	[[Category: Andersson, E.]]
		+	[[Category: Einarsson, E.]]
		+	[[Category: Engstrom, A.]]
		+	[[Category: Forsberg, Z.]]
		+	[[Category: Hansson, H.]]
		+	[[Category: Igarashi, K.]]
		+	[[Category: Jonsson, K H.M.]]
		+	[[Category: Kawai, R.]]
		+	[[Category: Samejima, M.]]
		+	[[Category: Sandgren, M.]]
		+	[[Category: Stahlberg, J.]]
		+	[[Category: Vasur, J.]]
		+	[[Category: Widmalm, G.]]
		+	[[Category: 6-glucan]]
		+	[[Category: Basidiomycete]]
		+	[[Category: Beta sandwich]]
		+	[[Category: Beta-1\]]
		+	[[Category: Beta-glucanase]]
		+	[[Category: Cyclical poysaccharide]]
		+	[[Category: Family 16]]
		+	[[Category: Gh16]]
		+	[[Category: Gh7]]
		+	[[Category: Glycosyl hydrolase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Lam16a]]
		+	[[Category: Laminarin]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:32:18 2010''