2wnw - Revision history

OCA at 10:15, 9 May 2024

2024-05-09T10:15:03Z

←Older revision		Revision as of 10:15, 9 May 2024
Line 3:		Line 3:
	<StructureSection load='2wnw' size='340' side='right'caption='[[2wnw]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2wnw' size='340' side='right'caption='[[2wnw]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp.~~_enterica_serovar_typhimurium_str~~.~~_lt2~~ Salmonella enterica subsp. enterica serovar ~~typhimurium~~ str. ~~lt2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WNW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WNW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [https://pdbe.org/2wnw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [https://www.ebi.ac.uk/pdbsum/2wnw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [https://pdbe.org/2wnw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [https://www.ebi.ac.uk/pdbsum/2wnw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnw ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9KIJ7_SALTM Q9KIJ7_SALTM]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Salmonella enterica subsp. enterica serovar ~~typhimurium~~ str. ~~lt2~~]]	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
-	[[Category: Kim, J H]]	+	[[Category: Kim J-H]]
-	[[Category: Kim, K J]]	+	[[Category: Kim K-J]]
-	[[Category: Kim, Y G]]	+	[[Category: Kim Y-G]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: O-glycosyl hydrolase family 30]]~~	+
-	~~[[Category: Salmonella typhimurium~~]]	+

OCA at 11:11, 6 April 2022

2022-04-06T11:11:44Z

←Older revision		Revision as of 11:11, 6 April 2022
Line 3:		Line 3:
	<StructureSection load='2wnw' size='340' side='right'caption='[[2wnw]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2wnw' size='340' side='right'caption='[[2wnw]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2WNW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WNW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [~~http~~://pdbe.org/2wnw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wnw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [https://pdbe.org/2wnw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [https://www.ebi.ac.uk/pdbsum/2wnw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnw ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:58, 1 July 2020

2020-07-01T08:58:03Z

←Older revision		Revision as of 08:58, 1 July 2020
Line 1:		Line 1:

	==The crystal structure of SrfJ from salmonella typhimurium==		==The crystal structure of SrfJ from salmonella typhimurium==
-	<StructureSection load='2wnw' size='340' side='right' caption='[[2wnw]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='2wnw' size='340' side='right'caption='[[2wnw]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WNW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WNW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [http://pdbe.org/2wnw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [http://www.ebi.ac.uk/pdbsum/2wnw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [http://pdbe.org/2wnw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [http://www.ebi.ac.uk/pdbsum/2wnw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnw ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
	[[Category: Kim, J H]]		[[Category: Kim, J H]]

OCA at 09:29, 26 September 2018

2018-09-26T09:29:48Z

←Older revision		Revision as of 09:29, 26 September 2018
Line 1:		Line 1:
-	==~~THE CRYSTAL STRUCTURE OF SRFJ FROM SALMONELLA TYPHIMURIUM~~==	+
		+	==The crystal structure of SrfJ from salmonella typhimurium==
	<StructureSection load='2wnw' size='340' side='right' caption='[[2wnw]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2wnw' size='340' side='right' caption='[[2wnw]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Salty Salty~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [http://pdbe.org/2wnw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [http://www.ebi.ac.uk/pdbsum/2wnw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [http://pdbe.org/2wnw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [http://www.ebi.ac.uk/pdbsum/2wnw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wnw ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wnw_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wnw_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 29:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Salty~~]]	+	[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
	[[Category: Kim, J H]]		[[Category: Kim, J H]]
	[[Category: Kim, K J]]		[[Category: Kim, K J]]

OCA at 07:22, 7 February 2016

2016-02-07T07:22:47Z

←Older revision		Revision as of 07:22, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='2wnw' size='340' side='right' caption='[[2wnw]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2wnw' size='340' side='right' caption='[[2wnw]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [http://www.ebi.ac.uk/pdbsum/2wnw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [http://pdbe.org/2wnw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [http://www.ebi.ac.uk/pdbsum/2wnw PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wnw ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wnw" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Salmonella enterica subsp. enterica serovar typhimurium str. lt2~~]]	+	[[Category: Salty]]
	[[Category: Kim, J H]]		[[Category: Kim, J H]]
	[[Category: Kim, K J]]		[[Category: Kim, K J]]

OCA at 10:40, 20 January 2015

2015-01-20T10:40:14Z

←Older revision		Revision as of 10:40, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNW FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [http://www.ebi.ac.uk/pdbsum/2wnw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [http://www.ebi.ac.uk/pdbsum/2wnw PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
-	[[Category: Kim, J H.]]	+	[[Category: Kim, J H]]
-	[[Category: Kim, K J.]]	+	[[Category: Kim, K J]]
-	[[Category: Kim, Y G.]]	+	[[Category: Kim, Y G]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: O-glycosyl hydrolase family 30]]		[[Category: O-glycosyl hydrolase family 30]]
	[[Category: Salmonella typhimurium]]		[[Category: Salmonella typhimurium]]

OCA at 01:36, 1 October 2014

2014-10-01T01:36:11Z

←Older revision		Revision as of 01:36, 1 October 2014
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-	[[~~Image~~:2wnw.~~png\|left~~\|200px]]	+	==THE CRYSTAL STRUCTURE OF SRFJ FROM SALMONELLA TYPHIMURIUM==
		+	<StructureSection load='2wnw' size='340' side='right' caption='[[2wnw]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNW FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wnw RCSB], [http://www.ebi.ac.uk/pdbsum/2wnw PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/2wnw_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	To cause infection, Salmonella enterica serovar Typhimurium uses type III secretion systems, which are encoded on two Salmonella pathogenicity islands, SPI-1 and SPI-2, the latter of which is thought to play a crucial role in bacterial proliferation in Salmonella-containing vacuoles (SCVs) after invading cells. S. Typhimurium SrfJ, located outside SPI-2, is also known to be involved in Salmonella pathogenicity and has high amino acid sequence homology with human lysosomal glucosylceramidase (GlcCerase). We present the first crystal structure of SrfJ at a resolution of 1.8 A. The overall fold of SrfJ shares high structure similarities with that of human GlcCerase, comprising two distinctive domains: a (beta/alpha)(8)-barrel catalytic domain and a beta-sandwich domain. As in human GlcCerase, the pocket-shaped active site of SrfJ is located on the C-terminal side of the barrel, and two conserved glutamic acid residues are used for the enzyme catalysis. Moreover, a glycerol-bound form of SrfJ reveals that the glucose ring moiety of the substrate might similarly bind to the enzyme as to human GlcCerase, suggesting that SrfJ might function as a glycoside hydrolase. Although some structural differences are observed between SrfJ and human GlcCerase in the substrate entrance of the active site, we speculate that, based on the high structural similarities to human GlcCerase in the overall fold and the active-site environment, SrfJ might have a GlcCerase activity and use the activity to enhance Salmonella virulence by modifying SCV membrane lipids.

-	~~{{STRUCTURE_2wnw\| PDB=2wnw \| SCENE= }}~~	+	Crystal structure of the Salmonella enterica serovar typhimurium virulence factor SrfJ, a glycoside hydrolase family enzyme.,Kim YG, Kim JH, Kim KJ J Bacteriol. 2009 Nov;191(21):6550-4. Epub 2009 Aug 28. PMID:19717598<ref>PMID:19717598</ref>

-	~~===THE CRYSTAL STRUCTURE OF SRFJ FROM SALMONELLA TYPHIMURIUM===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19717598}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2wnw]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Salmonella_enterica_subsp~~.~~_enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019717598<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
	[[Category: Kim, J H.]]		[[Category: Kim, J H.]]

OCA: Protected "2wnw" [edit=sysop:move=sysop]

2013-01-07T19:38:50Z

Protected "2wnw" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:38, 7 January 2013

OCA at 19:38, 7 January 2013

2013-01-07T19:38:46Z

←Older revision		Revision as of 19:38, 7 January 2013
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-	~~{{Seed}}~~	+	[[Image:2wnw.png\|left\|200px]]
-	[[Image:2wnw.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2wnw", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2wnw\| PDB=2wnw \| SCENE= }}		{{STRUCTURE_2wnw\| PDB=2wnw \| SCENE= }}

	===THE CRYSTAL STRUCTURE OF SRFJ FROM SALMONELLA TYPHIMURIUM===		===THE CRYSTAL STRUCTURE OF SRFJ FROM SALMONELLA TYPHIMURIUM===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19717598}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19717598 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_19717598}}		{{ABSTRACT_PUBMED_19717598}}

	==About this Structure==		==About this Structure==
-	~~2WNW~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA].	+	[[2wnw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19717598~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019717598</ref><references group="xtra"/>
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
	[[Category: Kim, J H.]]		[[Category: Kim, J H.]]
Line 31:		Line 19:
	[[Category: O-glycosyl hydrolase family 30]]		[[Category: O-glycosyl hydrolase family 30]]
	[[Category: Salmonella typhimurium]]		[[Category: Salmonella typhimurium]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 16:11:45 2010''

OCA at 14:11, 3 March 2010

2010-03-03T14:11:46Z

←Older revision		Revision as of 14:11, 3 March 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:2wnw.jpg\|left\|200px]]

-	The ~~entry 2wnw~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2wnw", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2wnw\| PDB=2wnw \| SCENE= }}

-	~~Authors: Kim, Y.-G., Kim, J.-H., Kim, K.-J.~~	+	===THE CRYSTAL STRUCTURE OF SRFJ FROM SALMONELLA TYPHIMURIUM===

-	Description: The crystal structure of SrfJ from salmonella typhimurium

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Aug~~ ~~5 09~~:33:~~00 2009~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19717598}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19717598 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19717598}}
		+
		+	==About this Structure==
		+	2WNW is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNW OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19717598</ref><references group="xtra"/>
		+	[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
		+	[[Category: Kim, J H.]]
		+	[[Category: Kim, K J.]]
		+	[[Category: Kim, Y G.]]
		+	[[Category: Hydrolase]]
		+	[[Category: O-glycosyl hydrolase family 30]]
		+	[[Category: Salmonella typhimurium]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 16:11:45 2010''