2wsm - Revision history

OCA at 10:15, 20 December 2023

2023-12-20T10:15:13Z

←Older revision		Revision as of 10:15, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='2wsm' size='340' side='right'caption='[[2wsm]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2wsm' size='340' side='right'caption='[[2wsm]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wsm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Arcfu Arcfu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WSM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wsm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_DSM_4304 Archaeoglobus fulgidus DSM 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WSM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsm OCA], [https://pdbe.org/2wsm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wsm RCSB], [https://www.ebi.ac.uk/pdbsum/2wsm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wsm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsm OCA], [https://pdbe.org/2wsm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wsm RCSB], [https://www.ebi.ac.uk/pdbsum/2wsm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wsm ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/O28903_ARCFU O28903_ARCFU]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arcfu~~]]	+	[[Category: Archaeoglobus fulgidus DSM 4304]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Li, T]]	+	[[Category: Li T]]
-	[[Category: Wong~~, K B]]~~	+	[[Category: Wong KB]]
-	~~[[Category: Metal binding protein~~]]	+

OCA at 11:15, 6 April 2022

2022-04-06T11:15:15Z

←Older revision		Revision as of 11:15, 6 April 2022
Line 3:		Line 3:
	<StructureSection load='2wsm' size='340' side='right'caption='[[2wsm]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2wsm' size='340' side='right'caption='[[2wsm]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wsm]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2WSM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wsm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WSM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsm OCA], [~~http~~://pdbe.org/2wsm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wsm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wsm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wsm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsm OCA], [https://pdbe.org/2wsm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wsm RCSB], [https://www.ebi.ac.uk/pdbsum/2wsm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wsm ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 09:08, 1 July 2020

2020-07-01T09:08:16Z

←Older revision		Revision as of 09:08, 1 July 2020
Line 1:		Line 1:

	==Crystal structure of Hydrogenase Maturation Factor HypB From Archaeoglobus Fulgidus==		==Crystal structure of Hydrogenase Maturation Factor HypB From Archaeoglobus Fulgidus==
-	<StructureSection load='2wsm' size='340' side='right' caption='[[2wsm]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='2wsm' size='340' side='right'caption='[[2wsm]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wsm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WSM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wsm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WSM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsm OCA], [http://pdbe.org/2wsm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wsm RCSB], [http://www.ebi.ac.uk/pdbsum/2wsm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wsm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsm OCA], [http://pdbe.org/2wsm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wsm RCSB], [http://www.ebi.ac.uk/pdbsum/2wsm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wsm ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 28:		Line 28:

	==See Also==		==See Also==
-	*[[HypA-HypB-HypC-HypD-HypE-HypF\|HypA-HypB-HypC-HypD-HypE-HypF]]	+	*[[HypA%2C HypB%2C HypC%2C HypD%2C HypE and HypF 3D structures\|HypA%2C HypB%2C HypC%2C HypD%2C HypE and HypF 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Arcfu]]		[[Category: Arcfu]]
		+	[[Category: Large Structures]]
	[[Category: Li, T]]		[[Category: Li, T]]
	[[Category: Wong, K B]]		[[Category: Wong, K B]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]

OCA at 08:54, 26 September 2018

2018-09-26T08:54:32Z

←Older revision		Revision as of 08:54, 26 September 2018
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ws/2wsm_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ws/2wsm_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 2wsm" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2wsm" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[HypA-HypB-HypC-HypD-HypE-HypF\|HypA-HypB-HypC-HypD-HypE-HypF]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:00, 5 August 2016

2016-08-05T08:00:25Z

←Older revision		Revision as of 08:00, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of Hydrogenase Maturation Factor HypB From Archaeoglobus Fulgidus==		==Crystal structure of Hydrogenase Maturation Factor HypB From Archaeoglobus Fulgidus==
	<StructureSection load='2wsm' size='340' side='right' caption='[[2wsm]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2wsm' size='340' side='right' caption='[[2wsm]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wsm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Archaeoglobus_fulgidus Archaeoglobus fulgidus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WSM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wsm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WSM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wsm RCSB], [http://www.ebi.ac.uk/pdbsum/2wsm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsm OCA], [http://pdbe.org/2wsm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wsm RCSB], [http://www.ebi.ac.uk/pdbsum/2wsm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wsm ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wsm ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wsm" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Archaeoglobus fulgidus~~]]	+	[[Category: Arcfu]]
	[[Category: Li, T]]		[[Category: Li, T]]
	[[Category: Wong, K B]]		[[Category: Wong, K B]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]

OCA at 21:12, 3 January 2015

2015-01-03T21:12:14Z

←Older revision		Revision as of 21:12, 3 January 2015
Line 2:		Line 2:
	<StructureSection load='2wsm' size='340' side='right' caption='[[2wsm]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2wsm' size='340' side='right' caption='[[2wsm]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wsm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA]. <br>	+	<table><tr><td colspan='2'>[[2wsm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WSM FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene~~><br>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wsm RCSB], [http://www.ebi.ac.uk/pdbsum/2wsm PDBsum]</span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wsm RCSB], [http://www.ebi.ac.uk/pdbsum/2wsm PDBsum]</span></td></tr>	+	</table>
-	<table>	+
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 22:
	Structural basis for GTP-dependent dimerization of hydrogenase maturation factor HypB.,Chan KH, Li T, Wong CO, Wong KB PLoS One. 2012;7(1):e30547. Epub 2012 Jan 20. PMID:22276211<ref>PMID:22276211</ref>		Structural basis for GTP-dependent dimerization of hydrogenase maturation factor HypB.,Chan KH, Li T, Wong CO, Wong KB PLoS One. 2012;7(1):e30547. Epub 2012 Jan 20. PMID:22276211<ref>PMID:22276211</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 30:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Archaeoglobus fulgidus]]		[[Category: Archaeoglobus fulgidus]]
-	[[Category: Li, T.]]	+	[[Category: Li, T]]
-	[[Category: Wong, K B.]]	+	[[Category: Wong, K B]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]

OCA at 08:32, 7 May 2014

2014-05-07T08:32:52Z

←Older revision		Revision as of 08:32, 7 May 2014
Line 1:		Line 1:
-	[[~~Image~~:2wsm.~~png\|left~~\|200px]]	+	==Crystal structure of Hydrogenase Maturation Factor HypB From Archaeoglobus Fulgidus==
		+	<StructureSection load='2wsm' size='340' side='right' caption='[[2wsm]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wsm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wsm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wsm RCSB], [http://www.ebi.ac.uk/pdbsum/2wsm PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ws/2wsm_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Maturation of [NiFe]-hydrogenase requires the insertion of iron, cyanide and carbon monoxide, followed by nickel, to the catalytic core of the enzyme. Hydrogenase maturation factor HypB is a metal-binding GTPase that is essential for the nickel delivery to the hydrogenase. Here we report the crystal structure of Archeoglobus fulgidus HypB (AfHypB) in apo-form. We showed that AfHypB recognizes guanine nucleotide using Asp-194 on the G5 loop despite having a non-canonical NKxA G4-motif. Structural comparison with the GTPgammaS-bound Methanocaldococcus jannaschii HypB identifies conformational changes in the switch I region, which bring an invariant Asp-72 to form an intermolecular salt-bridge with another invariant residue Lys-148 upon GTP binding. Substitution of K148A abolished GTP-dependent dimerization of AfHypB, but had no significant effect on the guanine nucleotide binding and on the intrinsic GTPase activity. In vivo complementation study in Escherichia coli showed that the invariant lysine residue is required for in vivo maturation of hydrogenase. Taken together, our results suggest that GTP-dependent dimerization of HypB is essential for hydrogenase maturation. It is likely that a nickel ion is loaded to an extra metal binding site at the dimeric interface of GTP-bound HypB and transferred to the hydrogenase upon GTP hydrolysis.

-	<!--	+	Structural basis for GTP-dependent dimerization of hydrogenase maturation factor HypB.,Chan KH, Li T, Wong CO, Wong KB PLoS One. 2012;7(1):e30547. Epub 2012 Jan 20. PMID:22276211<ref>PMID:22276211</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2wsm"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2wsm\| PDB=2wsm \| SCENE= }}~~	+

-	~~===Crystal structure of Hydrogenase Maturation Factor HypB~~ From ~~Archaeoglobus Fulgidus===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_22276211}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 22276211 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_22276211}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2wsm]] is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022276211<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Archaeoglobus fulgidus]]		[[Category: Archaeoglobus fulgidus]]
	[[Category: Li, T.]]		[[Category: Li, T.]]
	[[Category: Wong, K B.]]		[[Category: Wong, K B.]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]

OCA: Protected "2wsm" [edit=sysop:move=sysop]

2012-04-25T08:07:27Z

Protected "2wsm" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:07, 25 April 2012

OCA at 08:07, 25 April 2012

2012-04-25T08:07:25Z

←Older revision		Revision as of 08:07, 25 April 2012
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-	{{Seed}}
	[[Image:2wsm.png\|left\|200px]]		[[Image:2wsm.png\|left\|200px]]

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	{{STRUCTURE_2wsm\| PDB=2wsm \| SCENE= }}		{{STRUCTURE_2wsm\| PDB=2wsm \| SCENE= }}

-	===~~CRYSTAL STRUCTURE OF HYDROGENASE MATURATION FACTOR HYPB FROM ARCHAEOGLOBUS FULGIDUS~~===	+	===Crystal structure of Hydrogenase Maturation Factor HypB From Archaeoglobus Fulgidus===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22276211}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22276211 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22276211}}

	==About this Structure==		==About this Structure==
-	~~2WSM~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA].	+	[[2wsm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WSM OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022276211</ref><references group="xtra"/>
	[[Category: Archaeoglobus fulgidus]]		[[Category: Archaeoglobus fulgidus]]
	[[Category: Li, T.]]		[[Category: Li, T.]]
	[[Category: Wong, K B.]]		[[Category: Wong, K B.]]
-	[[Category: Hydrogenase maturation factor]]
-	[[Category: Hypb]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 07:44:28 2010''

OCA at 04:35, 29 September 2010

2010-09-29T04:35:13Z

←Older revision		Revision as of 04:35, 29 September 2010
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-	[[Image:2wsm.~~jpg~~\|left\|200px]]	+	[[Image:2wsm.png\|left\|200px]]

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-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep ~~22 14~~:41:51 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 07:44:28 2010''