2x22 - Revision history

OCA at 10:22, 20 December 2023

2023-12-20T10:22:25Z

←Older revision		Revision as of 10:22, 20 December 2023
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	<StructureSection load='2x22' size='340' side='right'caption='[[2x22]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2x22' size='340' side='right'caption='[[2x22]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x22]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Myctu Myctu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X22 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x22]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X22 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE~~-~~ADENINE-DINUCLEOTIDE'>NAD</scene>~~, ~~<scene name='pdbligand=TCU:5-HEXYL-~~2~~-(2-METHYLPHENOXY)PHENOL'>TCU</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL'>TCU</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Enoyl~~-~~[acyl~~-~~carrier~~-~~protein]_reductase_~~(~~NADH) Enoyl~~-~~[acyl-carrier-protein] reductase (NADH~~)~~], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [https://pdbe.org/2x22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [https://www.ebi.ac.uk/pdbsum/2x22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x22 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [https://pdbe.org/2x22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [https://www.ebi.ac.uk/pdbsum/2x22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x22 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Myctu]]~~	+	[[Category: Mycobacterium tuberculosis H37Rv]]
-	~~[[Category: Ende, C W.am~~]]	+	[[Category: Kisker C]]
-	[[Category: Kisker, C]]	+	[[Category: Liu N]]
-	[[Category: Liu, N]]	+	[[Category: Luckner SR]]
-	[[Category: Luckner~~, S R~~]]	+	[[Category: Tonge PJ]]
-	[[Category: Tonge~~, P J~~]]	+	[[Category: Am Ende CW]]
-	[[Category: ~~Antibiotic resistance]]~~	+
-	~~[[Category: Fatty acid biosynthesis]]~~	+
-	~~[[Category: Lipid synthesis]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 10:44, 13 April 2022

2022-04-13T10:44:40Z

←Older revision		Revision as of 10:44, 13 April 2022
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	<StructureSection load='2x22' size='340' side='right'caption='[[2x22]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2x22' size='340' side='right'caption='[[2x22]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x22]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2X22 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x22]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X22 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL'>TCU</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL'>TCU</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [~~http~~://pdbe.org/2x22 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2x22 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2x22 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [https://pdbe.org/2x22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [https://www.ebi.ac.uk/pdbsum/2x22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x22 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 15:03, 8 July 2020

2020-07-08T15:03:28Z

←Older revision		Revision as of 15:03, 8 July 2020
Line 1:		Line 1:

	==crystal structure of M. tuberculosis InhA inhibited by PT70==		==crystal structure of M. tuberculosis InhA inhibited by PT70==
-	<StructureSection load='2x22' size='340' side='right' caption='[[2x22]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='2x22' size='340' side='right'caption='[[2x22]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2X22 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2X22 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL'>TCU</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL'>TCU</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [http://pdbe.org/2x22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [http://www.ebi.ac.uk/pdbsum/2x22 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x22 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [http://pdbe.org/2x22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [http://www.ebi.ac.uk/pdbsum/2x22 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x22 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Enoyl-Acyl-Carrier Protein Reductase\|Enoyl-Acyl-Carrier Protein Reductase]]	+	*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures\|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Myctu]]		[[Category: Myctu]]
	[[Category: Ende, C W.am]]		[[Category: Ende, C W.am]]

OCA at 09:25, 3 October 2018

2018-10-03T09:25:14Z

←Older revision		Revision as of 09:25, 3 October 2018
Line 1:		Line 1:
-	==~~CRYSTAL STRUCTURE OF~~ M. ~~TUBERCULOSIS INHA INHIBITED BY~~ PT70==	+
		+	==crystal structure of M. tuberculosis InhA inhibited by PT70==
	<StructureSection load='2x22' size='340' side='right' caption='[[2x22]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2x22' size='340' side='right' caption='[[2x22]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [http://pdbe.org/2x22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [http://www.ebi.ac.uk/pdbsum/2x22 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [http://pdbe.org/2x22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [http://www.ebi.ac.uk/pdbsum/2x22 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x22 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x2/2x22_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x2/2x22_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Myctu]]		[[Category: Myctu]]
-	[[Category: Ende, C W.Am]]	+	[[Category: Ende, C W.am]]
	[[Category: Kisker, C]]		[[Category: Kisker, C]]
	[[Category: Liu, N]]		[[Category: Liu, N]]

OCA at 14:51, 8 February 2016

2016-02-08T14:51:23Z

←Older revision		Revision as of 14:51, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='2x22' size='340' side='right' caption='[[2x22]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2x22' size='340' side='right' caption='[[2x22]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mycobacterium_tuberculosis Mycobacterium tuberculosis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X22 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X22 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL'>TCU</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL'>TCU</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [http://www.ebi.ac.uk/pdbsum/2x22 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [http://pdbe.org/2x22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [http://www.ebi.ac.uk/pdbsum/2x22 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2x22 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2x22" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mycobacterium tuberculosis~~]]	+	[[Category: Myctu]]
	[[Category: Ende, C W.Am]]		[[Category: Ende, C W.Am]]
	[[Category: Kisker, C]]		[[Category: Kisker, C]]

OCA at 11:24, 20 January 2015

2015-01-20T11:24:36Z

←Older revision		Revision as of 11:24, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2x22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X22 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2x22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X22 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL'>TCU</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL'>TCU</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [http://www.ebi.ac.uk/pdbsum/2x22 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [http://www.ebi.ac.uk/pdbsum/2x22 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
-	[[Category: Ende, C W.Am.]]	+	[[Category: Ende, C W.Am]]
-	[[Category: Kisker, C.]]	+	[[Category: Kisker, C]]
-	[[Category: Liu, N.]]	+	[[Category: Liu, N]]
-	[[Category: Luckner, S R.]]	+	[[Category: Luckner, S R]]
-	[[Category: Tonge, P J.]]	+	[[Category: Tonge, P J]]
	[[Category: Antibiotic resistance]]		[[Category: Antibiotic resistance]]
	[[Category: Fatty acid biosynthesis]]		[[Category: Fatty acid biosynthesis]]
	[[Category: Lipid synthesis]]		[[Category: Lipid synthesis]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 09:54, 29 September 2014

2014-09-29T09:54:57Z

←Older revision		Revision as of 09:54, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2x22.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF M. TUBERCULOSIS INHA INHIBITED BY PT70==
		+	<StructureSection load='2x22' size='340' side='right' caption='[[2x22]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2x22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X22 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL'>TCU</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2h7m\|2h7m]], [[2aqi\|2aqi]], [[2h7p\|2h7p]], [[2b36\|2b36]], [[1bvr\|1bvr]], [[2aqk\|2aqk]], [[2b35\|2b35]], [[2h7i\|2h7i]], [[1zid\|1zid]], [[1p45\|1p45]], [[1enz\|1enz]], [[1p44\|1p44]], [[1eny\|1eny]], [[2b37\|2b37]], [[2nv6\|2nv6]], [[2x23\|2x23]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x22 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x22 RCSB], [http://www.ebi.ac.uk/pdbsum/2x22 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x2/2x22_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	InhA, the enoyl-ACP reductase in Mycobacterium tuberculosis is an attractive target for the development of novel drugs against tuberculosis, a disease that kills more than two million people each year. InhA is the target of the current first line drug isoniazid for the treatment of tuberculosis infections. Compounds that directly target InhA and do not require activation by the mycobacterial catalase-peroxidase KatG are promising candidates for treating infections caused by isoniazid-resistant strains. Previously we reported the synthesis of several diphenyl ethers with nanomolar affinity for InhA. However, these compounds are rapid reversible inhibitors of the enzyme, and based on the knowledge that long drug target residence times are an important factor for in vivo drug activity, we set out to generate a slow onset inhibitor of InhA using structure-based drug design. 2-(o-Tolyloxy)-5-hexylphenol (PT70) is a slow, tight binding inhibitor of InhA with a K(1) value of 22 pm. PT70 binds preferentially to the InhA x NAD(+) complex and has a residence time of 24 min on the target, which is 14,000 times longer than that of the rapid reversible inhibitor from which it is derived. The 1.8 A crystal structure of the ternary complex between InhA, NAD(+), and PT70 reveals the molecular details of enzyme-inhibitor recognition and supports the hypothesis that slow onset inhibition is coupled to ordering of an active site loop, which leads to the closure of the substrate-binding pocket.

-	~~{{STRUCTURE_2x22\| PDB=2x22 \| SCENE= }}~~	+	A slow, tight binding inhibitor of InhA, the enoyl-acyl carrier protein reductase from Mycobacterium tuberculosis.,Luckner SR, Liu N, am Ende CW, Tonge PJ, Kisker C J Biol Chem. 2010 May 7;285(19):14330-7. Epub 2010 Mar 3. PMID:20200152<ref>PMID:20200152</ref>

-	~~===CRYSTAL STRUCTURE OF M. TUBERCULOSIS INHA INHIBITED BY PT70===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20200152}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2x22]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA].~~	+

	==See Also==		==See Also==
	*[[Enoyl-Acyl-Carrier Protein Reductase\|Enoyl-Acyl-Carrier Protein Reductase]]		*[[Enoyl-Acyl-Carrier Protein Reductase\|Enoyl-Acyl-Carrier Protein Reductase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020200152<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
	[[Category: Ende, C W.Am.]]		[[Category: Ende, C W.Am.]]

OCA at 10:30, 20 October 2012

2012-10-20T10:30:59Z

←Older revision		Revision as of 10:30, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2x22]] is a 2 chain structure ~~of [[Enoyl-Acyl-Carrier Protein Reductase]]~~ with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA].	+	[[2x22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA].

	==See Also==		==See Also==

OCA: Protected "2x22" [edit=sysop:move=sysop]

2012-07-26T02:22:24Z

Protected "2x22" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:22, 26 July 2012

OCA at 02:22, 26 July 2012

2012-07-26T02:22:23Z

←Older revision		Revision as of 02:22, 26 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2x22.png\|left\|200px]]		[[Image:2x22.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2x22", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2x22\| PDB=2x22 \| SCENE= }}		{{STRUCTURE_2x22\| PDB=2x22 \| SCENE= }}

	===CRYSTAL STRUCTURE OF M. TUBERCULOSIS INHA INHIBITED BY PT70===		===CRYSTAL STRUCTURE OF M. TUBERCULOSIS INHA INHIBITED BY PT70===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20200152}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20200152 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20200152}}		{{ABSTRACT_PUBMED_20200152}}

	==About this Structure==		==About this Structure==
-	~~2X22~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA].	+	[[2x22]] is a 2 chain structure of [[Enoyl-Acyl-Carrier Protein Reductase]] with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X22 OCA].
		+
		+	==See Also==
		+	*[[Enoyl-Acyl-Carrier Protein Reductase\|Enoyl-Acyl-Carrier Protein Reductase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20200152~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020200152</ref><references group="xtra"/>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
	[[Category: Ende, C W.Am.]]		[[Category: Ende, C W.Am.]]
Line 34:		Line 25:
	[[Category: Lipid synthesis]]		[[Category: Lipid synthesis]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 12 10:32:42 2010''