2xd2 - Revision history

OCA at 10:24, 9 May 2024

2024-05-09T10:24:49Z

←Older revision		Revision as of 10:24, 9 May 2024
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	<StructureSection load='2xd2' size='340' side='right'caption='[[2xd2]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2xd2' size='340' side='right'caption='[[2xd2]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xd2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Strpn Strpn~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XD2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xd2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XD2 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>~~[[~~2xd3~~\|~~2xd3~~]]~~</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd2 OCA], [https://pdbe.org/2xd2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xd2 RCSB], [https://www.ebi.ac.uk/pdbsum/2xd2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd2 OCA], [https://pdbe.org/2xd2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xd2 RCSB], [https://www.ebi.ac.uk/pdbsum/2xd2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MALX_STRPN MALX_STRPN]] Binding protein for maltose and maltodextrin; involved in its cellular uptake.	+	[https://www.uniprot.org/uniprot/MALX_STRPN MALX_STRPN] Binding protein for maltose and maltodextrin; involved in its cellular uptake.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Strpn~~]]	+	[[Category: Streptococcus pneumoniae TIGR4]]
-	[[Category: Abbott~~, D W~~]]	+	[[Category: Abbott DW]]
-	[[Category: Boraston~~, A B]]~~	+	[[Category: Boraston AB]]
-	~~[[Category: Bueren, A Lammerts van~~]]	+	[[Category: Higgins MA]]
-	[[Category: Higgins~~, M A~~]]	+	[[Category: Hyrnuik S]]
-	[[Category: Hyrnuik, S]]	+	[[Category: Lammerts van Bueren A]]
-	[[Category: ~~Pluvinage, B~~]]	+	[[Category: Pluvinage B]]
-	[[Category: ~~Alpha-glucan]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Solute-binding protein]]~~	+
-	~~[[Category: Sugar binding protein]]~~	+
-	~~[[Category: Sugar transport]]~~	+
-	~~[[Category: Virulence~~]]	+

OCA at 10:50, 13 April 2022

2022-04-13T10:50:20Z

←Older revision		Revision as of 10:50, 13 April 2022
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	<StructureSection load='2xd2' size='340' side='right'caption='[[2xd2]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2xd2' size='340' side='right'caption='[[2xd2]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xd2]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2XD2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xd2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XD2 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xd3\|2xd3]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2xd3\|2xd3]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd2 OCA], [~~http~~://pdbe.org/2xd2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2xd2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2xd2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd2 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd2 OCA], [https://pdbe.org/2xd2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xd2 RCSB], [https://www.ebi.ac.uk/pdbsum/2xd2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MALX_STRPN MALX_STRPN]] Binding protein for maltose and maltodextrin; involved in its cellular uptake.	+	[[https://www.uniprot.org/uniprot/MALX_STRPN MALX_STRPN]] Binding protein for maltose and maltodextrin; involved in its cellular uptake.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 15:11, 8 July 2020

2020-07-08T15:11:10Z

←Older revision		Revision as of 15:11, 8 July 2020
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	==The crystal structure of MalX from Streptococcus pneumoniae==		==The crystal structure of MalX from Streptococcus pneumoniae==
-	<StructureSection load='2xd2' size='340' side='right' caption='[[2xd2]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='2xd2' size='340' side='right'caption='[[2xd2]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xd2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2XD2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xd2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2XD2 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xd3\|2xd3]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xd3\|2xd3]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd2 OCA], [http://pdbe.org/2xd2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xd2 RCSB], [http://www.ebi.ac.uk/pdbsum/2xd2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd2 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd2 OCA], [http://pdbe.org/2xd2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xd2 RCSB], [http://www.ebi.ac.uk/pdbsum/2xd2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Maltose-binding protein\|Maltose-binding protein]]	+	*[[Maltose-binding protein 3D structures\|Maltose-binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Strpn]]		[[Category: Strpn]]
	[[Category: Abbott, D W]]		[[Category: Abbott, D W]]

OCA at 09:53, 3 October 2018

2018-10-03T09:53:32Z

←Older revision		Revision as of 09:53, 3 October 2018
Line 1:		Line 1:

-	==~~THE CRYSTAL STRUCTURE OF MALX FROM STREPTOCOCCUS PNEUMONIAE~~==	+	==The crystal structure of MalX from Streptococcus pneumoniae==
	<StructureSection load='2xd2' size='340' side='right' caption='[[2xd2]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2xd2' size='340' side='right' caption='[[2xd2]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xd/2xd2_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xd/2xd2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 38:		Line 38:
	[[Category: Abbott, D W]]		[[Category: Abbott, D W]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]
-	[[Category: Bueren, A Lammerts ~~Van~~]]	+	[[Category: Bueren, A Lammerts van]]
	[[Category: Higgins, M A]]		[[Category: Higgins, M A]]
	[[Category: Hyrnuik, S]]		[[Category: Hyrnuik, S]]

OCA at 16:48, 4 August 2016

2016-08-04T16:48:18Z

←Older revision		Revision as of 16:48, 4 August 2016
Line 1:		Line 1:
		+
	==THE CRYSTAL STRUCTURE OF MALX FROM STREPTOCOCCUS PNEUMONIAE==		==THE CRYSTAL STRUCTURE OF MALX FROM STREPTOCOCCUS PNEUMONIAE==
	<StructureSection load='2xd2' size='340' side='right' caption='[[2xd2]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2xd2' size='340' side='right' caption='[[2xd2]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xd2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_pneumoniae Streptococcus pneumoniae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XD2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xd2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XD2 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xd3\|2xd3]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xd3\|2xd3]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xd2 RCSB], [http://www.ebi.ac.uk/pdbsum/2xd2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd2 OCA], [http://pdbe.org/2xd2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xd2 RCSB], [http://www.ebi.ac.uk/pdbsum/2xd2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xd2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2xd2" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptococcus pneumoniae~~]]	+	[[Category: Strpn]]
	[[Category: Abbott, D W]]		[[Category: Abbott, D W]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]

OCA at 11:06, 25 December 2014

2014-12-25T11:06:54Z

←Older revision		Revision as of 11:06, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2xd2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XD2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2xd2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XD2 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xd3\|2xd3]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xd3\|2xd3]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xd2 RCSB], [http://www.ebi.ac.uk/pdbsum/2xd2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xd2 RCSB], [http://www.ebi.ac.uk/pdbsum/2xd2 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MALX_STRPN MALX_STRPN]] Binding protein for maltose and maltodextrin; involved in its cellular uptake.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Streptococcus pneumoniae]]		[[Category: Streptococcus pneumoniae]]
-	[[Category: Abbott, D W.]]	+	[[Category: Abbott, D W]]
-	[[Category: Boraston, A B.]]	+	[[Category: Boraston, A B]]
-	[[Category: Bueren, A Lammerts Van.]]	+	[[Category: Bueren, A Lammerts Van]]
-	[[Category: Higgins, M A.]]	+	[[Category: Higgins, M A]]
-	[[Category: Hyrnuik, S.]]	+	[[Category: Hyrnuik, S]]
-	[[Category: Pluvinage, B.]]	+	[[Category: Pluvinage, B]]
	[[Category: Alpha-glucan]]		[[Category: Alpha-glucan]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]

OCA at 01:05, 2 October 2014

2014-10-02T01:05:29Z

←Older revision		Revision as of 01:05, 2 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2xd2.~~png~~\|~~left~~\|200px]]	+	==THE CRYSTAL STRUCTURE OF MALX FROM STREPTOCOCCUS PNEUMONIAE==
		+	<StructureSection load='2xd2' size='340' side='right' caption='[[2xd2]], [[Resolution\|resolution]] 2.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2xd2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XD2 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xd3\|2xd3]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xd2 RCSB], [http://www.ebi.ac.uk/pdbsum/2xd2 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xd/2xd2_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The genome of Streptococcus pneumoniae strains, as typified by the TIGR4 strain, contain several genes encoding proteins putatively involved in alpha-glucan degradation, modification and synthesis. The extracellular components comprise an ATP binding cassette-transporter with its solute binding protein, MalX, and the hydrolytic enzyme SpuA. We show that of the commonly occurring exogenous alpha-glucans, S. pneumoniae TIGR4 is only able to grow on glycogen in a MalX- and SpuA-dependent manner. SpuA is able to degrade glycogen into a ladder of alpha-1,4-glucooligosaccharides while the high-affinity interaction (K(a) approximately 10(6) M(-1)) of MalX with maltooligosaccharides plays a key role in promoting the selective uptake of the glycogen degradation products that are produced by SpuA. The X-ray crystallographic analyses of apo- and complexed MalX illuminate the protein's specificity for the degradation products of glycogen and its striking ability to recognize the helical structure of the ligand. Overall, the results of this work provide new structural and functional insight into streptococcal alpha-glucan metabolism while supplying biochemical support for the hypothesis that the substrate of the S. pneumoniaealpha-glucan metabolizing machinery is glycogen, which in a human host is abundant in lung epithelial cells, a common target for invasive S. pneumoniae.

-	~~{{STRUCTURE_2xd2\| PDB=2xd2 \| SCENE= }}~~	+	The molecular basis of glycogen breakdown and transport in Streptococcus pneumoniae.,Abbott DW, Higgins MA, Hyrnuik S, Pluvinage B, Lammerts van Bueren A, Boraston AB Mol Microbiol. 2010 Jul 1;77(1):183-99. Epub 2010 May 19. PMID:20497336<ref>PMID:20497336</ref>

-	~~===THE CRYSTAL STRUCTURE OF MALX FROM STREPTOCOCCUS PNEUMONIAE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20497336}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2xd2]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA].~~	+

	==See Also==		==See Also==
	*[[Maltose-binding protein\|Maltose-binding protein]]		*[[Maltose-binding protein\|Maltose-binding protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020497336<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Streptococcus pneumoniae]]		[[Category: Streptococcus pneumoniae]]
	[[Category: Abbott, D W.]]		[[Category: Abbott, D W.]]

OCA at 15:59, 20 October 2012

2012-10-20T15:59:09Z

←Older revision		Revision as of 15:59, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2xd2]] is a 2 chain structure ~~of [[Maltose-binding protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA].	+	[[2xd2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA].

	==See Also==		==See Also==

OCA at 20:12, 26 July 2012

2012-07-26T20:12:58Z

←Older revision		Revision as of 20:12, 26 July 2012
Line 1:		Line 1:
	[[Image:2xd2.png\|left\|200px]]		[[Image:2xd2.png\|left\|200px]]

-	<!--
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-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_2xd2\| PDB=2xd2 \| SCENE= }}		{{STRUCTURE_2xd2\| PDB=2xd2 \| SCENE= }}

	===THE CRYSTAL STRUCTURE OF MALX FROM STREPTOCOCCUS PNEUMONIAE===		===THE CRYSTAL STRUCTURE OF MALX FROM STREPTOCOCCUS PNEUMONIAE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20497336}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20497336 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20497336}}		{{ABSTRACT_PUBMED_20497336}}

	==About this Structure==		==About this Structure==
-	[[2xd2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA].	+	[[2xd2]] is a 2 chain structure of [[Maltose-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD2 OCA].
		+
		+	==See Also==
		+	*[[Maltose-binding protein\|Maltose-binding protein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20497336~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020497336</ref><references group="xtra"/>
	[[Category: Streptococcus pneumoniae]]		[[Category: Streptococcus pneumoniae]]
	[[Category: Abbott, D W.]]		[[Category: Abbott, D W.]]

OCA: Protected "2xd2" [edit=sysop:move=sysop]

2010-12-29T18:31:08Z

Protected "2xd2" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:31, 29 December 2010