2xly - Revision history

OCA at 08:01, 23 August 2023

2023-08-23T08:01:13Z

←Older revision		Revision as of 08:01, 23 August 2023
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	<StructureSection load='2xly' size='340' side='right'caption='[[2xly]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='2xly' size='340' side='right'caption='[[2xly]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xly]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Strrc Strrc~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XLY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xly]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_roseochromogenus_subsp._oscitans Streptomyces roseochromogenus subsp. oscitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XLY FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>~~[[~~2xlq~~\|~~2xlq~~]]~~</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.1Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xly OCA], [https://pdbe.org/2xly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xly RCSB], [https://www.ebi.ac.uk/pdbsum/2xly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xly ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xly OCA], [https://pdbe.org/2xly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xly RCSB], [https://www.ebi.ac.uk/pdbsum/2xly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xly ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CLOQ_STRRC CLOQ_STRRC]] Magnesium-independent aromatic prenyltransferase that catalyzes the irreversible transfer of a dimethylallyl group to 4-hydroxyphenylpyruvate to produce the ring A structure in the clorobiocin biosynthesis pathway. Clorobiocin is an aminocoumarin family antibiotic.<ref>PMID:12618544</ref>	+	[https://www.uniprot.org/uniprot/CLOQ_STRRC CLOQ_STRRC] Magnesium-independent aromatic prenyltransferase that catalyzes the irreversible transfer of a dimethylallyl group to 4-hydroxyphenylpyruvate to produce the ring A structure in the clorobiocin biosynthesis pathway. Clorobiocin is an aminocoumarin family antibiotic.<ref>PMID:12618544</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Strrc~~]]	+	[[Category: Streptomyces roseochromogenus subsp. oscitans]]
-	[[Category: Heide, L]]	+	[[Category: Heide L]]
-	[[Category: Keller, S]]	+	[[Category: Keller S]]
-	[[Category: Lawson~~, D M~~]]	+	[[Category: Lawson DM]]
-	[[Category: Metzger, U]]	+	[[Category: Metzger U]]
-	[[Category: Stevenson~~, C E.M]]~~	+	[[Category: Stevenson CEM]]
-	~~[[Category: Antibiotic biosynthesis]]~~	+
-	~~[[Category: Pt-barrel]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 14:51, 17 November 2021

2021-11-17T14:51:15Z

←Older revision		Revision as of 14:51, 17 November 2021
Line 1:		Line 1:

	==Structural and Mechanistic Analysis of the Magnesium-Independent Aromatic Prenyltransferase CloQ from the Clorobiocin Biosynthetic Pathway==		==Structural and Mechanistic Analysis of the Magnesium-Independent Aromatic Prenyltransferase CloQ from the Clorobiocin Biosynthetic Pathway==
-	<StructureSection load='2xly' size='340' side='right' caption='[[2xly]], [[Resolution\|resolution]] 3.10Å' scene=''>	+	<StructureSection load='2xly' size='340' side='right'caption='[[2xly]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xly]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Strrc Strrc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2XLY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xly]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Strrc Strrc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XLY FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xlq\|2xlq]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2xlq\|2xlq]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2xly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xly OCA], [~~http~~://pdbe.org/2xly PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2xly RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2xly PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2xly ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xly OCA], [https://pdbe.org/2xly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xly RCSB], [https://www.ebi.ac.uk/pdbsum/2xly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xly ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CLOQ_STRRC CLOQ_STRRC]] Magnesium-independent aromatic prenyltransferase that catalyzes the irreversible transfer of a dimethylallyl group to 4-hydroxyphenylpyruvate to produce the ring A structure in the clorobiocin biosynthesis pathway. Clorobiocin is an aminocoumarin family antibiotic.<ref>PMID:12618544</ref>	+	[[https://www.uniprot.org/uniprot/CLOQ_STRRC CLOQ_STRRC]] Magnesium-independent aromatic prenyltransferase that catalyzes the irreversible transfer of a dimethylallyl group to 4-hydroxyphenylpyruvate to produce the ring A structure in the clorobiocin biosynthesis pathway. Clorobiocin is an aminocoumarin family antibiotic.<ref>PMID:12618544</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Strrc]]		[[Category: Strrc]]
	[[Category: Heide, L]]		[[Category: Heide, L]]

OCA at 07:58, 6 March 2019

2019-03-06T07:58:01Z

←Older revision		Revision as of 07:58, 6 March 2019
Line 1:		Line 1:

	==Structural and Mechanistic Analysis of the Magnesium-Independent Aromatic Prenyltransferase CloQ from the Clorobiocin Biosynthetic Pathway==		==Structural and Mechanistic Analysis of the Magnesium-Independent Aromatic Prenyltransferase CloQ from the Clorobiocin Biosynthetic Pathway==
-	<StructureSection load='2xly' size='340' side='right' caption='[[2xly]], [[Resolution\|resolution]] 3.10Å' scene=''>	+	<StructureSection load='2xly' size='340' side='right' caption='[[2xly]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2xly]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strrc Strrc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XLY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2xly]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strrc Strrc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XLY FirstGlance]. <br>

OCA at 09:52, 3 October 2018

2018-10-03T09:52:53Z

←Older revision		Revision as of 09:52, 3 October 2018
Line 1:		Line 1:

-	==~~STRUCTURAL AND MECHANISTIC ANALYSIS OF THE MAGNESIUM~~-~~INDEPENDENT AROMATIC PRENYLTRANSFERASE CLOQ FROM THE CLOROBIOCIN BIOSYNTHETIC PATHWAY~~==	+	==Structural and Mechanistic Analysis of the Magnesium-Independent Aromatic Prenyltransferase CloQ from the Clorobiocin Biosynthetic Pathway==
	<StructureSection load='2xly' size='340' side='right' caption='[[2xly]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='2xly' size='340' side='right' caption='[[2xly]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xly]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~'streptomyces_roseochromogenes_subsp._oscitans' 'streptomyces roseochromogenes subsp. oscitans'~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XLY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xly]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strrc Strrc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XLY FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xlq\|2xlq]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xlq\|2xlq]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xly OCA], [http://pdbe.org/2xly PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xly RCSB], [http://www.ebi.ac.uk/pdbsum/2xly PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xly ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xly OCA], [http://pdbe.org/2xly PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xly RCSB], [http://www.ebi.ac.uk/pdbsum/2xly PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xly ProSAT]</span></td></tr>
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptomyces roseochromogenes subsp. oscitans~~]]	+	[[Category: Strrc]]
	[[Category: Heide, L]]		[[Category: Heide, L]]
	[[Category: Keller, S]]		[[Category: Keller, S]]

OCA at 17:35, 11 August 2016

2016-08-11T17:35:44Z

←Older revision		Revision as of 17:35, 11 August 2016
Line 1:		Line 1:
		+
	==STRUCTURAL AND MECHANISTIC ANALYSIS OF THE MAGNESIUM-INDEPENDENT AROMATIC PRENYLTRANSFERASE CLOQ FROM THE CLOROBIOCIN BIOSYNTHETIC PATHWAY==		==STRUCTURAL AND MECHANISTIC ANALYSIS OF THE MAGNESIUM-INDEPENDENT AROMATIC PRENYLTRANSFERASE CLOQ FROM THE CLOROBIOCIN BIOSYNTHETIC PATHWAY==
	<StructureSection load='2xly' size='340' side='right' caption='[[2xly]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='2xly' size='340' side='right' caption='[[2xly]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xly]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptomyces_roseochromogenes_subsp~~._oscitans ~~Streptomyces~~ roseochromogenes subsp. oscitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XLY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xly]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/'streptomyces_roseochromogenes_subsp._oscitans' 'streptomyces roseochromogenes subsp. oscitans']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XLY FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xlq\|2xlq]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xlq\|2xlq]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xly OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xly RCSB], [http://www.ebi.ac.uk/pdbsum/2xly PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xly OCA], [http://pdbe.org/2xly PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xly RCSB], [http://www.ebi.ac.uk/pdbsum/2xly PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xly ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CLOQ_STRRC CLOQ_STRRC]] Magnesium-independent aromatic prenyltransferase that catalyzes the irreversible transfer of a dimethylallyl group to 4-hydroxyphenylpyruvate to produce the ring A structure in the clorobiocin biosynthesis pathway. Clorobiocin is an aminocoumarin family antibiotic.<ref>PMID:12618544</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2xly" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:21, 25 January 2015

2015-01-25T08:21:55Z

←Older revision		Revision as of 08:21, 25 January 2015
Line 19:		Line 19:
	</StructureSection>		</StructureSection>
	[[Category: Streptomyces roseochromogenes subsp. oscitans]]		[[Category: Streptomyces roseochromogenes subsp. oscitans]]
-	[[Category: Heide, L.]]	+	[[Category: Heide, L]]
-	[[Category: Keller, S.]]	+	[[Category: Keller, S]]
-	[[Category: Lawson, D M.]]	+	[[Category: Lawson, D M]]
-	[[Category: Metzger, U.]]	+	[[Category: Metzger, U]]
-	[[Category: Stevenson, C E.M.]]	+	[[Category: Stevenson, C E.M]]
	[[Category: Antibiotic biosynthesis]]		[[Category: Antibiotic biosynthesis]]
	[[Category: Pt-barrel]]		[[Category: Pt-barrel]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 13:23, 22 October 2014

2014-10-22T13:23:41Z

←Older revision		Revision as of 13:23, 22 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2xly.~~png~~\|~~left~~\|~~200px~~]]	+	==STRUCTURAL AND MECHANISTIC ANALYSIS OF THE MAGNESIUM-INDEPENDENT AROMATIC PRENYLTRANSFERASE CLOQ FROM THE CLOROBIOCIN BIOSYNTHETIC PATHWAY==
		+	<StructureSection load='2xly' size='340' side='right' caption='[[2xly]], [[Resolution\|resolution]] 3.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2xly]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_roseochromogenes_subsp._oscitans Streptomyces roseochromogenes subsp. oscitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XLY FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xlq\|2xlq]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xly OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xly RCSB], [http://www.ebi.ac.uk/pdbsum/2xly PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	CloQ is an aromatic prenyltransferase from the clorobiocin biosynthetic pathway of Streptomyces roseochromogenes var. oscitans. It is involved in the synthesis of the prenylated hydroxybenzoate moiety of the antibiotic, specifically catalyzing the attachment of a dimethylallyl moiety to 4-hydroxyphenylpyruvate. Herein, we report the crystal structure of CloQ and use it as a framework for interpreting biochemical data from both wild-type proteins and variant proteins. CloQ belongs to the aromatic prenyltransferase family, which is characterized by an unusual core fold comprising five consecutive alphaalphabetabeta elements that form a central 10-stranded anti-parallel beta-barrel. The latter delineates a solvent-accessible cavity where substrates bind and catalysis takes place. This cavity has well-defined polar and nonpolar regions, which have distinct roles in substrate binding and facilitate a Friedel-Crafts-type mechanism. We propose that the juxtaposition of five positively charged residues in the polar region circumvents the necessity for a Mg(2+), which, by contrast, is a strict requirement for the majority of prenyltransferases characterized to date. Our structure of CloQ complexed with 4-hydroxyphenylpyruvate reveals the formation of a covalent link between the substrate and Cys215 to yield a thiohemiketal species. Through site-directed mutagenesis, we show that this link is not essential for enzyme activity in vitro. Furthermore, we demonstrate that CloQ will accept alternative substrates and, therefore, has the capacity to generate a range of prenylated compounds. Since prenylation is thought to enhance the bioactivity of many natural products, CloQ offers considerable promise as a biocatalyst for the chemoenzymatic synthesis of novel compounds with therapeutic potential.

-	~~{{STRUCTURE_2xly\| PDB=2xly \| SCENE= }}~~	+	Structure and Mechanism of the Magnesium-Independent Aromatic Prenyltransferase CloQ from the Clorobiocin Biosynthetic Pathway.,Metzger U, Keller S, Stevenson CE, Heide L, Lawson DM J Mol Biol. 2010 Oct 12. PMID:20946900<ref>PMID:20946900</ref>

-	~~===STRUCTURAL AND MECHANISTIC ANALYSIS OF THE MAGNESIUM-INDEPENDENT AROMATIC PRENYLTRANSFERASE CLOQ FROM THE CLOROBIOCIN BIOSYNTHETIC PATHWAY===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20946900}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2xly]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptomyces_roseochromogenes_subsp~~.~~_oscitans Streptomyces roseochromogenes subsp. oscitans]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020946900<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Streptomyces roseochromogenes subsp. oscitans]]		[[Category: Streptomyces roseochromogenes subsp. oscitans]]
	[[Category: Heide, L.]]		[[Category: Heide, L.]]

OCA: Protected "2xly" [edit=sysop:move=sysop]

2013-01-07T20:31:42Z

Protected "2xly" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:31, 7 January 2013

OCA at 20:31, 7 January 2013

2013-01-07T20:31:39Z

←Older revision		Revision as of 20:31, 7 January 2013
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-	{{Seed}}
	[[Image:2xly.png\|left\|200px]]		[[Image:2xly.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2xly\| PDB=2xly \| SCENE= }}		{{STRUCTURE_2xly\| PDB=2xly \| SCENE= }}

	===STRUCTURAL AND MECHANISTIC ANALYSIS OF THE MAGNESIUM-INDEPENDENT AROMATIC PRENYLTRANSFERASE CLOQ FROM THE CLOROBIOCIN BIOSYNTHETIC PATHWAY===		===STRUCTURAL AND MECHANISTIC ANALYSIS OF THE MAGNESIUM-INDEPENDENT AROMATIC PRENYLTRANSFERASE CLOQ FROM THE CLOROBIOCIN BIOSYNTHETIC PATHWAY===

-
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	==About this Structure==		==About this Structure==
-	~~2XLY~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_roseochromogenes_subsp._oscitans Streptomyces roseochromogenes subsp. oscitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA].	+	[[2xly]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_roseochromogenes_subsp._oscitans Streptomyces roseochromogenes subsp. oscitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XLY OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20946900~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020946900</ref><references group="xtra"/>
	[[Category: Streptomyces roseochromogenes subsp. oscitans]]		[[Category: Streptomyces roseochromogenes subsp. oscitans]]
	[[Category: Heide, L.]]		[[Category: Heide, L.]]
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	[[Category: Pt-barrel]]		[[Category: Pt-barrel]]
	[[Category: Transferase]]		[[Category: Transferase]]
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OCA at 08:08, 8 December 2010

2010-12-08T08:08:40Z

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