2yf3 - Revision history

OCA at 08:13, 23 August 2023

2023-08-23T08:13:24Z

←Older revision		Revision as of 08:13, 23 August 2023
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	<StructureSection load='2yf3' size='340' side='right'caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2yf3' size='340' side='right'caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yf3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Deira Deira~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YF3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yf3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YF3 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2yf9\|2yf9]], [[2yfc\|2yfc]], [[2yeu\|2yeu]], [[2yf4\|2yf4]], [[2yfd\|2yfd]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>[https://en.wikipedia.org/wiki/Nucleoside-triphosphate_diphosphatase Nucleoside-triphosphate diphosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.19 3.6.1.19] </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf3 OCA], [https://pdbe.org/2yf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yf3 RCSB], [https://www.ebi.ac.uk/pdbsum/2yf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yf3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf3 OCA], [https://pdbe.org/2yf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yf3 RCSB], [https://www.ebi.ac.uk/pdbsum/2yf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yf3 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9RS96_DEIRA Q9RS96_DEIRA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Deira~~]]	+	[[Category: Deinococcus radiodurans R1]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Nucleoside-triphosphate diphosphatase]]~~	+	[[Category: Goncalves AMD]]
-	[[Category: Goncalves~~, A M.D~~]]	+	[[Category: McSweeney SM]]
-	[[Category: McSweeney~~, S M~~]]	+	[[Category: DeSanctis D]]
-	[[Category: DeSanctis, D]]	+
-	~~[[Category: Dimeric dutpase]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 15:04, 17 November 2021

2021-11-17T15:04:54Z

←Older revision		Revision as of 15:04, 17 November 2021
Line 3:		Line 3:
	<StructureSection load='2yf3' size='340' side='right'caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2yf3' size='340' side='right'caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yf3]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Deira Deira]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2YF3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yf3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Deira Deira]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YF3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yf9\|2yf9]], [[2yfc\|2yfc]], [[2yeu\|2yeu]], [[2yf4\|2yf4]], [[2yfd\|2yfd]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yf9\|2yf9]], [[2yfc\|2yfc]], [[2yeu\|2yeu]], [[2yf4\|2yf4]], [[2yfd\|2yfd]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Nucleoside-triphosphate_diphosphatase Nucleoside-triphosphate diphosphatase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.19 3.6.1.19] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Nucleoside-triphosphate_diphosphatase Nucleoside-triphosphate diphosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.19 3.6.1.19] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2yf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf3 OCA], [~~http~~://pdbe.org/2yf3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2yf3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2yf3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2yf3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf3 OCA], [https://pdbe.org/2yf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yf3 RCSB], [https://www.ebi.ac.uk/pdbsum/2yf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yf3 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:46, 21 August 2019

2019-08-21T07:46:38Z

←Older revision		Revision as of 07:46, 21 August 2019
Line 1:		Line 1:

	==Crystal structure of DR2231, the MazG-like protein from Deinococcus radiodurans, complex with manganese==		==Crystal structure of DR2231, the MazG-like protein from Deinococcus radiodurans, complex with manganese==
-	<StructureSection load='2yf3' size='340' side='right' caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='2yf3' size='340' side='right'caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2yf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Deira Deira]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YF3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2yf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Deira Deira]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YF3 FirstGlance]. <br>
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Deira]]		[[Category: Deira]]
		+	[[Category: Large Structures]]
	[[Category: Nucleoside-triphosphate diphosphatase]]		[[Category: Nucleoside-triphosphate diphosphatase]]
	[[Category: Goncalves, A M.D]]		[[Category: Goncalves, A M.D]]

OCA at 07:35, 16 November 2017

2017-11-16T07:35:29Z

←Older revision		Revision as of 07:35, 16 November 2017
Line 1:		Line 1:

-	==~~CRYSTAL STRUCTURE OF~~ DR2231, ~~THE MAZG~~-~~LIKE PROTEIN FROM DEINOCOCCUS RADIODURANS~~, ~~COMPLEX WITH MANGANESE~~==	+	==Crystal structure of DR2231, the MazG-like protein from Deinococcus radiodurans, complex with manganese==
	<StructureSection load='2yf3' size='340' side='right' caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2yf3' size='340' side='right' caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 24:		Line 24:
	[[Category: Deira]]		[[Category: Deira]]
	[[Category: Nucleoside-triphosphate diphosphatase]]		[[Category: Nucleoside-triphosphate diphosphatase]]
-	[[Category: Desanctis, D]]
	[[Category: Goncalves, A M.D]]		[[Category: Goncalves, A M.D]]
-	[[Category: ~~Mcsweeney~~, S M]]	+	[[Category: McSweeney, S M]]
		+	[[Category: DeSanctis, D]]
	[[Category: Dimeric dutpase]]		[[Category: Dimeric dutpase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 10:17, 5 August 2016

2016-08-05T10:17:58Z

←Older revision		Revision as of 10:17, 5 August 2016
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF DR2231, THE MAZG-LIKE PROTEIN FROM DEINOCOCCUS RADIODURANS, COMPLEX WITH MANGANESE==		==CRYSTAL STRUCTURE OF DR2231, THE MAZG-LIKE PROTEIN FROM DEINOCOCCUS RADIODURANS, COMPLEX WITH MANGANESE==
	<StructureSection load='2yf3' size='340' side='right' caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2yf3' size='340' side='right' caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Deinococcus_radiodurans Deinococcus radiodurans~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YF3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Deira Deira]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YF3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yf9\|2yf9]], [[2yfc\|2yfc]], [[2yeu\|2yeu]], [[2yf4\|2yf4]], [[2yfd\|2yfd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yf9\|2yf9]], [[2yfc\|2yfc]], [[2yeu\|2yeu]], [[2yf4\|2yf4]], [[2yfd\|2yfd]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-triphosphate_diphosphatase Nucleoside-triphosphate diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.19 3.6.1.19] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-triphosphate_diphosphatase Nucleoside-triphosphate diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.19 3.6.1.19] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yf3 RCSB], [http://www.ebi.ac.uk/pdbsum/2yf3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf3 OCA], [http://pdbe.org/2yf3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yf3 RCSB], [http://www.ebi.ac.uk/pdbsum/2yf3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yf3 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2yf3" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Deinococcus radiodurans~~]]	+	[[Category: Deira]]
	[[Category: Nucleoside-triphosphate diphosphatase]]		[[Category: Nucleoside-triphosphate diphosphatase]]
	[[Category: Desanctis, D]]		[[Category: Desanctis, D]]

OCA at 23:19, 3 January 2015

2015-01-03T23:19:32Z

←Older revision		Revision as of 23:19, 3 January 2015
Line 2:		Line 2:
	<StructureSection load='2yf3' size='340' side='right' caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2yf3' size='340' side='right' caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA]. <br>	+	<table><tr><td colspan='2'>[[2yf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YF3 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yf9\|2yf9]], [[2yfc\|2yfc]], [[2yeu\|2yeu]], [[2yf4\|2yf4]], [[2yfd\|2yfd]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yf9\|2yf9]], [[2yfc\|2yfc]], [[2yeu\|2yeu]], [[2yf4\|2yf4]], [[2yfd\|2yfd]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Glucokinase Glucokinase~~], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.~~2 2~~.7.1.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-triphosphate_diphosphatase Nucleoside-triphosphate diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.19 3.6.1.19] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yf3 RCSB], [http://www.ebi.ac.uk/pdbsum/2yf3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yf3 RCSB], [http://www.ebi.ac.uk/pdbsum/2yf3 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 14:
	Structural and Functional Insights into DR2231 Protein, the MazG-like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus radiodurans.,Goncalves AM, de Sanctis D, McSweeney SM J Biol Chem. 2011 Sep 2;286(35):30691-705. Epub 2011 Jul 6. PMID:21733847<ref>PMID:21733847</ref>		Structural and Functional Insights into DR2231 Protein, the MazG-like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus radiodurans.,Goncalves AM, de Sanctis D, McSweeney SM J Biol Chem. 2011 Sep 2;286(35):30691-705. Epub 2011 Jul 6. PMID:21733847<ref>PMID:21733847</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 22:		Line 22:
	[[Category: Deinococcus radiodurans]]		[[Category: Deinococcus radiodurans]]
	[[Category: Nucleoside-triphosphate diphosphatase]]		[[Category: Nucleoside-triphosphate diphosphatase]]
-	[[Category: Desanctis, D.]]	+	[[Category: Desanctis, D]]
-	[[Category: Goncalves, A M.D.]]	+	[[Category: Goncalves, A M.D]]
-	[[Category: Mcsweeney, S M.]]	+	[[Category: Mcsweeney, S M]]
	[[Category: Dimeric dutpase]]		[[Category: Dimeric dutpase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 07:50, 14 May 2014

2014-05-14T07:50:01Z

←Older revision		Revision as of 07:50, 14 May 2014
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-	[[~~Image:~~2yf3.~~png~~\|~~left~~\|~~200px~~]]	+	==CRYSTAL STRUCTURE OF DR2231, THE MAZG-LIKE PROTEIN FROM DEINOCOCCUS RADIODURANS, COMPLEX WITH MANGANESE==
		+	<StructureSection load='2yf3' size='340' side='right' caption='[[2yf3]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2yf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yf9\|2yf9]], [[2yfc\|2yfc]], [[2yeu\|2yeu]], [[2yf4\|2yf4]], [[2yfd\|2yfd]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yf3 RCSB], [http://www.ebi.ac.uk/pdbsum/2yf3 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Deinococcus radiodurans is among the very few bacterial species extremely resistant to ionizing radiation, UV light, oxidizing agents, and cycles of prolonged desiccation. The proteome of D. radiodurans reflects the evolutionary pressure exerted by chronic exposure to (nonradioactive) forms of DNA and protein damage. A clear example of this adaptation is the overrepresentation of protein families involved in the removal of non-canonical nucleoside triphosphates (NTPs) whose incorporation into nascent DNA would promote mutagenesis and DNA damage. The three-dimensional structure of the DR2231 protein has been solved at 1.80 A resolution. This protein had been classified as an all-alpha-helical MazG-like protein. The present study confirms that it holds the basic structural module characteristic of the MazG superfamily; two helices form a rigid domain, and two helices form a mobile domain and connecting loops. Contrary to what is known of MazG proteins, DR2231 protein shows a functional affinity with dUTPases. Enzymatic and isothermal calorimetry assays have demonstrated high specificity toward dUTP but an inability to hydrolyze dTTP, a typical feature of dUTPases. Co-crystallization with the product of hydrolysis, dUMP, in the presence of magnesium or manganese cations, suggests similarities with the dUTP/dUDP hydrolysis mechanism reported for dimeric dUTPases. The genome of D. radiodurans encodes for all enzymes required for dTTP synthesis from dCMP, thus bypassing the need of a dUTPase. We postulate that DR2231 protein is not essential to D. radiodurans and rather performs "house-cleaning" functions within the framework of oxidative stress response. We further propose DR2231 protein as an evolutionary precursor of dimeric dUTPases.

-	<!--	+	Structural and Functional Insights into DR2231 Protein, the MazG-like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus radiodurans.,Goncalves AM, de Sanctis D, McSweeney SM J Biol Chem. 2011 Sep 2;286(35):30691-705. Epub 2011 Jul 6. PMID:21733847<ref>PMID:21733847</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2yf3"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2yf3\| PDB=2yf3 \| SCENE= }}~~	+

-	~~===CRYSTAL STRUCTURE OF DR2231~~, ~~THE MAZG-LIKE PROTEIN FROM DEINOCOCCUS RADIODURANS, COMPLEX WITH MANGANESE===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21733847}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21733847 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21733847}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2yf3]] is a 6 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021733847<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Deinococcus radiodurans]]		[[Category: Deinococcus radiodurans]]
	[[Category: Nucleoside-triphosphate diphosphatase]]		[[Category: Nucleoside-triphosphate diphosphatase]]

OCA at 05:29, 7 September 2011

2011-09-07T05:29:13Z

←Older revision		Revision as of 05:29, 7 September 2011
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-	[[Image:2yf3.~~jpg~~\|left\|200px]]	+	[[Image:2yf3.png\|left\|200px]]

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	===CRYSTAL STRUCTURE OF DR2231, THE MAZG-LIKE PROTEIN FROM DEINOCOCCUS RADIODURANS, COMPLEX WITH MANGANESE===		===CRYSTAL STRUCTURE OF DR2231, THE MAZG-LIKE PROTEIN FROM DEINOCOCCUS RADIODURANS, COMPLEX WITH MANGANESE===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21733847}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21733847 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21733847}}

	==About this Structure==		==About this Structure==
	[[2yf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA].		[[2yf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021733847</ref><references group="xtra"/>
	[[Category: Deinococcus radiodurans]]		[[Category: Deinococcus radiodurans]]
	[[Category: Nucleoside-triphosphate diphosphatase]]		[[Category: Nucleoside-triphosphate diphosphatase]]

OCA at 18:53, 6 July 2011

2011-07-06T18:53:58Z

←Older revision		Revision as of 18:53, 6 July 2011
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-	~~'''Unreleased structure'''~~	+	[[Image:2yf3.jpg\|left\|200px]]

-	The ~~entry 2yf3~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2yf3", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2yf3\| PDB=2yf3 \| SCENE= }}

-	~~Authors: Goncalves~~, ~~A.M.D.~~, ~~deSanctis, D., McSweeney, S.M.~~	+	===CRYSTAL STRUCTURE OF DR2231, THE MAZG-LIKE PROTEIN FROM DEINOCOCCUS RADIODURANS, COMPLEX WITH MANGANESE===

-	~~Description: Crystal~~ structure ~~of DR2231, the MazG-like protein~~ from Deinococcus radiodurans, ~~complex with manganese~~	+
		+	==About this Structure==
		+	[[2yf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF3 OCA].
		+	[[Category: Deinococcus radiodurans]]
		+	[[Category: Nucleoside-triphosphate diphosphatase]]
		+	[[Category: Desanctis, D.]]
		+	[[Category: Goncalves, A M.D.]]
		+	[[Category: Mcsweeney, S M.]]
		+	[[Category: Dimeric dutpase]]
		+	[[Category: Hydrolase]]

OCA: Protected "2yf3" [edit=sysop:move=sysop]

2011-04-13T04:46:22Z

Protected "2yf3" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:46, 13 April 2011