2yg6 - Revision history

OCA at 08:13, 23 August 2023

2023-08-23T08:13:33Z

←Older revision		Revision as of 08:13, 23 August 2023
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	<StructureSection load='2yg6' size='340' side='right'caption='[[2yg6]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2yg6' size='340' side='right'caption='[[2yg6]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yg6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium~~ erythropolis~~" gray and thornton 1928~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YG6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yg6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YG6 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FAD:FLAVIN~~-~~ADENINE+DINUCLEOTIDE'>FAD</scene>~~, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[2yg3\|2yg3]], [[2yg4\|2yg4]], [[2yg5\|2yg5]], [[2yg7\|2yg7]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Putrescine_oxidase Putrescine oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.10 1.4.3.10]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yg6 OCA], [https://pdbe.org/2yg6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yg6 RCSB], [https://www.ebi.ac.uk/pdbsum/2yg6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yg6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yg6 OCA], [https://pdbe.org/2yg6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yg6 RCSB], [https://www.ebi.ac.uk/pdbsum/2yg6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yg6 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B0F9F6_RHOER B0F9F6_RHOER]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Mycobacterium erythropolis gray and thornton 1928]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Putrescine oxidase]]~~	+	[[Category: Rhodococcus erythropolis]]
-	~~[[Category: Duijn, E van~~]]	+	[[Category: Fraaije MW]]
-	[[Category: Fraaije~~, M W~~]]	+	[[Category: Kopacz MM]]
-	[[Category: Kopacz~~, M M~~]]	+	[[Category: Mattevi A]]
-	[[Category: Mattevi, A]]	+	[[Category: Rovida S]]
-	[[Category: Rovida, S]]	+	[[Category: Van Duijn E]]
-	[[Category: ~~Flavin]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 15:05, 17 November 2021

2021-11-17T15:05:04Z

←Older revision		Revision as of 15:05, 17 November 2021
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	==Structure-based redesign of cofactor binding in Putrescine Oxidase: P15I-A394C double mutant==		==Structure-based redesign of cofactor binding in Putrescine Oxidase: P15I-A394C double mutant==
-	<StructureSection load='2yg6' size='340' side='right' caption='[[2yg6]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='2yg6' size='340' side='right'caption='[[2yg6]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yg6]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YG6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2YG6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yg6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YG6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yg3\|2yg3]], [[2yg4\|2yg4]], [[2yg5\|2yg5]], [[2yg7\|2yg7]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yg3\|2yg3]], [[2yg4\|2yg4]], [[2yg5\|2yg5]], [[2yg7\|2yg7]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Putrescine_oxidase Putrescine oxidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.10 1.4.3.10] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Putrescine_oxidase Putrescine oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.10 1.4.3.10] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2yg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yg6 OCA], [~~http~~://pdbe.org/2yg6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2yg6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2yg6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2yg6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yg6 OCA], [https://pdbe.org/2yg6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yg6 RCSB], [https://www.ebi.ac.uk/pdbsum/2yg6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yg6 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</StructureSection>		</StructureSection>
	[[Category: Mycobacterium erythropolis gray and thornton 1928]]		[[Category: Mycobacterium erythropolis gray and thornton 1928]]
		+	[[Category: Large Structures]]
	[[Category: Putrescine oxidase]]		[[Category: Putrescine oxidase]]
	[[Category: Duijn, E van]]		[[Category: Duijn, E van]]

OCA at 06:04, 20 June 2018

2018-06-20T06:04:23Z

←Older revision		Revision as of 06:04, 20 June 2018
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-	==~~STRUCTURE~~-~~BASED REDESIGN OF COFACTOR BINDING IN PUTRESCINE OXIDASE~~: P15I-A394C ~~DOUBLE MUTANT~~==	+	==Structure-based redesign of cofactor binding in Putrescine Oxidase: P15I-A394C double mutant==
	<StructureSection load='2yg6' size='340' side='right' caption='[[2yg6]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2yg6' size='340' side='right' caption='[[2yg6]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 24:		Line 24:
	[[Category: Mycobacterium erythropolis gray and thornton 1928]]		[[Category: Mycobacterium erythropolis gray and thornton 1928]]
	[[Category: Putrescine oxidase]]		[[Category: Putrescine oxidase]]
-	[[Category: Duijn, E ~~Van~~]]	+	[[Category: Duijn, E van]]
	[[Category: Fraaije, M W]]		[[Category: Fraaije, M W]]
	[[Category: Kopacz, M M]]		[[Category: Kopacz, M M]]

OCA at 22:08, 5 August 2016

2016-08-05T22:08:10Z

←Older revision		Revision as of 22:08, 5 August 2016
Line 1:		Line 1:
		+
	==STRUCTURE-BASED REDESIGN OF COFACTOR BINDING IN PUTRESCINE OXIDASE: P15I-A394C DOUBLE MUTANT==		==STRUCTURE-BASED REDESIGN OF COFACTOR BINDING IN PUTRESCINE OXIDASE: P15I-A394C DOUBLE MUTANT==
	<StructureSection load='2yg6' size='340' side='right' caption='[[2yg6]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2yg6' size='340' side='right' caption='[[2yg6]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yg6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rhodococcus_erythropolis Rhodococcus~~ erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YG6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YG6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yg6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YG6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YG6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yg3\|2yg3]], [[2yg4\|2yg4]], [[2yg5\|2yg5]], [[2yg7\|2yg7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yg3\|2yg3]], [[2yg4\|2yg4]], [[2yg5\|2yg5]], [[2yg7\|2yg7]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Putrescine_oxidase Putrescine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.10 1.4.3.10] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Putrescine_oxidase Putrescine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.10 1.4.3.10] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yg6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yg6 RCSB], [http://www.ebi.ac.uk/pdbsum/2yg6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yg6 OCA], [http://pdbe.org/2yg6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yg6 RCSB], [http://www.ebi.ac.uk/pdbsum/2yg6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yg6 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2yg6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Mycobacterium erythropolis gray and thornton 1928]]
	[[Category: Putrescine oxidase]]		[[Category: Putrescine oxidase]]
-	[[Category: Rhodococcus erythropolis]]
	[[Category: Duijn, E Van]]		[[Category: Duijn, E Van]]
	[[Category: Fraaije, M W]]		[[Category: Fraaije, M W]]

OCA at 14:24, 18 December 2014

2014-12-18T14:24:01Z

←Older revision		Revision as of 14:24, 18 December 2014
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-	~~{{STRUCTURE_2yg6\| PDB=2yg6 \| SCENE= }}~~	+	==STRUCTURE-BASED REDESIGN OF COFACTOR BINDING IN PUTRESCINE OXIDASE: P15I-A394C DOUBLE MUTANT==
-	===STRUCTURE-BASED REDESIGN OF COFACTOR BINDING IN PUTRESCINE OXIDASE: P15I-A394C DOUBLE MUTANT===	+	<StructureSection load='2yg6' size='340' side='right' caption='[[2yg6]], [[Resolution\|resolution]] 2.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21486042}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2yg6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YG6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YG6 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yg3\|2yg3]], [[2yg4\|2yg4]], [[2yg5\|2yg5]], [[2yg7\|2yg7]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Putrescine_oxidase Putrescine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.10 1.4.3.10] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yg6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yg6 RCSB], [http://www.ebi.ac.uk/pdbsum/2yg6 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Putrescine oxidase (PuO) from Rhodococcus erythropolis is a soluble homodimeric flavoprotein, which oxidizes small aliphatic diamines. In this study, we report the crystal structures and cofactor binding properties of wild-type and mutant enzymes. From a structural viewpoint, PuO closely resembles the sequence-related human monoamine oxidases A and B. This similarity is striking in the flavin-binding site even if PuO does not covalently bind the cofactor as do the monoamine oxidases. A remarkable conserved feature is the cis peptide conformation of the Tyr residue whose conformation is important for substrate recognition in the active site cavity. The structure of PuO in complex with the reaction product reveals that Glu324 is crucial in recognizing the terminal amino group of the diamine substrate and explains the narrow substrate specificity of the enzyme. The structural analysis also provides clues for identification of residues that are responsible for the competitive binding of ADP versus FAD ( approximately 50% of wild-type PuO monomers isolated are occupied by ADP instead of FAD). By replacing Pro15, which is part of the dinucleotide-binding domain, enzyme preparations were obtained that are almost 100% in the FAD-bound form. Furthermore, mutants have been designed and prepared that form a covalent 8alpha-S-cysteinyl-FAD linkage. These data provide new insights into the molecular basis for substrate recognition in amine oxidases and demonstrate that engineering of flavoenzymes to introduce covalent linkage with the cofactor is a possible route to develop more stable protein molecules, better suited for biocatalytic purposes.

-	~~==About this~~ Structure==	+	Structure-based redesign of cofactor binding in putrescine oxidase.,Kopacz MM, Rovida S, van Duijn E, Fraaije MW, Mattevi A Biochemistry. 2011 May 17;50(19):4209-17. Epub 2011 Apr 21. PMID:21486042<ref>PMID:21486042</ref>
-	~~[[2yg6]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=2YG6 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:021486042</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Putrescine oxidase]]		[[Category: Putrescine oxidase]]
	[[Category: Rhodococcus erythropolis]]		[[Category: Rhodococcus erythropolis]]
-	[[Category: Duijn, E Van.]]	+	[[Category: Duijn, E Van]]
-	[[Category: Fraaije, M W.]]	+	[[Category: Fraaije, M W]]
-	[[Category: Kopacz, M M.]]	+	[[Category: Kopacz, M M]]
-	[[Category: Mattevi, A.]]	+	[[Category: Mattevi, A]]
-	[[Category: Rovida, S.]]	+	[[Category: Rovida, S]]
	[[Category: Flavin]]		[[Category: Flavin]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 09:41, 27 March 2013

2013-03-27T09:41:34Z

←Older revision		Revision as of 09:41, 27 March 2013
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-	[[Image:2yg6.jpg\|left\|200px]]
-
-	<!--
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	{{STRUCTURE_2yg6\| PDB=2yg6 \| SCENE= }}		{{STRUCTURE_2yg6\| PDB=2yg6 \| SCENE= }}
-
	===STRUCTURE-BASED REDESIGN OF COFACTOR BINDING IN PUTRESCINE OXIDASE: P15I-A394C DOUBLE MUTANT===		===STRUCTURE-BASED REDESIGN OF COFACTOR BINDING IN PUTRESCINE OXIDASE: P15I-A394C DOUBLE MUTANT===
-
-
-	<!--
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	{{ABSTRACT_PUBMED_21486042}}		{{ABSTRACT_PUBMED_21486042}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:021486042</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021486042</ref><references group="xtra"/><references/>
	[[Category: Putrescine oxidase]]		[[Category: Putrescine oxidase]]
	[[Category: Rhodococcus erythropolis]]		[[Category: Rhodococcus erythropolis]]
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	[[Category: Mattevi, A.]]		[[Category: Mattevi, A.]]
	[[Category: Rovida, S.]]		[[Category: Rovida, S.]]
		+	[[Category: Flavin]]
		+	[[Category: Oxidoreductase]]

OCA at 05:43, 18 May 2011

2011-05-18T05:43:12Z

←Older revision		Revision as of 05:43, 18 May 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2yg6.jpg\|left\|200px]]

-	The ~~entry 2yg6~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2yg6", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2yg6\| PDB=2yg6 \| SCENE= }}

-	~~Authors~~: ~~Kopacz, M.M., Rovida, S., van Duijn, E., Fraaije, M.W., Mattevi, A.~~	+	===STRUCTURE-BASED REDESIGN OF COFACTOR BINDING IN PUTRESCINE OXIDASE: P15I-A394C DOUBLE MUTANT===

-	~~Description~~: Structure-~~based redesign of cofactor binding in~~ Putrescine ~~Oxidase~~: ~~P15I-A394C double mutant~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21486042}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21486042 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21486042}}
		+
		+	==About this Structure==
		+	[[2yg6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YG6 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021486042</ref><references group="xtra"/>
		+	[[Category: Putrescine oxidase]]
		+	[[Category: Rhodococcus erythropolis]]
		+	[[Category: Duijn, E Van.]]
		+	[[Category: Fraaije, M W.]]
		+	[[Category: Kopacz, M M.]]
		+	[[Category: Mattevi, A.]]
		+	[[Category: Rovida, S.]]

OCA: Protected "2yg6" [edit=sysop:move=sysop]

2011-04-21T10:10:08Z

Protected "2yg6" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:10, 21 April 2011

OCA: New page: '''Unreleased structure''' The entry 2yg6 is ON HOLD until Paper Publication Authors: Kopacz, M.M., Rovida, S., van Duijn, E., Fraaije, M.W., Mattevi, A. Description: Structure-based r...

2011-04-21T10:10:07Z

New page: '''Unreleased structure''' The entry 2yg6 is ON HOLD until Paper Publication Authors: Kopacz, M.M., Rovida, S., van Duijn, E., Fraaije, M.W., Mattevi, A. Description: Structure-based r...

New page

'''Unreleased structure'''

The entry 2yg6 is ON HOLD until Paper Publication

Authors: Kopacz, M.M., Rovida, S., van Duijn, E., Fraaije, M.W., Mattevi, A.

Description: Structure-based redesign of cofactor binding in Putrescine Oxidase: P15I-A394C double mutant