2z71 - Revision history

OCA at 13:24, 1 November 2023

2023-11-01T13:24:03Z

←Older revision		Revision as of 13:24, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='2z71' size='340' side='right'caption='[[2z71]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2z71' size='340' side='right'caption='[[2z71]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2z71]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bacillus_sphaericus Bacillus~~ sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z71 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2z71]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z71 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=PNV:(2S,5R,6R)~~-3,~~3-DIMETHYL-7-OXO-6-(~~2~~-PHENOXYACETAMIDO)-4-THIA-1-+AZABICYCLO(3~~.~~2.0)HEPTANE-2-CARBOXYLIC+ACID'>PNV</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PNV:(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1-+AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC+ACID'>PNV</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase]~~, ~~with EC number [https://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=~~3~~.5.~~1~~.11~~ 3.5.~~1.11]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [https://pdbe.org/2z71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [https://www.ebi.ac.uk/pdbsum/2z71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z71 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [https://pdbe.org/2z71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [https://www.ebi.ac.uk/pdbsum/2z71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z71 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.	+	[https://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus sphaericus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Penicillin amidase~~]]	+	[[Category: Lysinibacillus sphaericus]]
-	[[Category: Brannigan, J]]	+	[[Category: Brannigan J]]
-	[[Category: Dodson~~, G G~~]]	+	[[Category: Dodson GG]]
-	[[Category: Pathak~~, M C~~]]	+	[[Category: Pathak MC]]
-	[[Category: Suresh~~, C G]]~~	+	[[Category: Suresh CG]]
-	~~[[Category: Antibiotic resistance]]~~	+
-	~~[[Category: Autoproteolysis]]~~	+
-	~~[[Category: Catalysis]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Penicillin]]~~	+
-	~~[[Category: Penicillin v acylase]]~~	+
-	~~[[Category: Precursor]]~~	+
-	~~[[Category: Zymogen~~]]	+

OCA at 07:13, 10 November 2021

2021-11-10T07:13:10Z

←Older revision		Revision as of 07:13, 10 November 2021
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	<StructureSection load='2z71' size='340' side='right'caption='[[2z71]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2z71' size='340' side='right'caption='[[2z71]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2z71]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacillus_sphaericus Bacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2Z71 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2z71]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sphaericus Bacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z71 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PNV:(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1-+AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC+ACID'>PNV</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PNV:(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1-+AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC+ACID'>PNV</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [~~http~~://pdbe.org/2z71 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2z71 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2z71 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [https://pdbe.org/2z71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [https://www.ebi.ac.uk/pdbsum/2z71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z71 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.	+	[[https://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 11:59, 29 July 2020

2020-07-29T11:59:04Z

←Older revision		Revision as of 11:59, 29 July 2020
Line 1:		Line 1:

	==Structure of truncated mutant CYS1GLY of penicillin V acylase from bacillus sphaericus co-crystallized with penicillin V==		==Structure of truncated mutant CYS1GLY of penicillin V acylase from bacillus sphaericus co-crystallized with penicillin V==
-	<StructureSection load='2z71' size='340' side='right' caption='[[2z71]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='2z71' size='340' side='right'caption='[[2z71]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2z71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sphaericus Bacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2Z71 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2z71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sphaericus Bacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2Z71 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNV:(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1-+AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC+ACID'>PNV</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PNV:(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1-+AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC+ACID'>PNV</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [http://pdbe.org/2z71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [http://www.ebi.ac.uk/pdbsum/2z71 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z71 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [http://pdbe.org/2z71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [http://www.ebi.ac.uk/pdbsum/2z71 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z71 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus sphaericus]]		[[Category: Bacillus sphaericus]]
		+	[[Category: Large Structures]]
	[[Category: Penicillin amidase]]		[[Category: Penicillin amidase]]
	[[Category: Brannigan, J]]		[[Category: Brannigan, J]]

OCA at 09:21, 17 October 2018

2018-10-17T09:21:12Z

←Older revision		Revision as of 09:21, 17 October 2018
Line 1:		Line 1:
		+
	==Structure of truncated mutant CYS1GLY of penicillin V acylase from bacillus sphaericus co-crystallized with penicillin V==		==Structure of truncated mutant CYS1GLY of penicillin V acylase from bacillus sphaericus co-crystallized with penicillin V==
	<StructureSection load='2z71' size='340' side='right' caption='[[2z71]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2z71' size='340' side='right' caption='[[2z71]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2z71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Lysinibacillus_sphaericus Lysinibacillus~~ sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z71 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2z71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sphaericus Bacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z71 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNV:(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1-+AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC+ACID'>PNV</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNV:(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1-+AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC+ACID'>PNV</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [http://pdbe.org/2z71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [http://www.ebi.ac.uk/pdbsum/2z71 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [http://pdbe.org/2z71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [http://www.ebi.ac.uk/pdbsum/2z71 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z71 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/2z71_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/2z71_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Lysinibacillus~~ sphaericus]]	+	[[Category: Bacillus sphaericus]]
	[[Category: Penicillin amidase]]		[[Category: Penicillin amidase]]
	[[Category: Brannigan, J]]		[[Category: Brannigan, J]]

OCA at 04:51, 9 February 2016

2016-02-09T04:51:01Z

←Older revision		Revision as of 04:51, 9 February 2016
Line 6:		Line 6:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [http://www.ebi.ac.uk/pdbsum/2z71 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [http://pdbe.org/2z71 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [http://www.ebi.ac.uk/pdbsum/2z71 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~PAC_BACSH PAC_BACSH~~]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.	+	[[http://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z71 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

OCA at 04:32, 25 December 2014

2014-12-25T04:32:54Z

←Older revision		Revision as of 04:32, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2z71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z71 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2z71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z71 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNV:(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1-+AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC+ACID'>PNV</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNV:(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1-+AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC+ACID'>PNV</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [http://www.ebi.ac.uk/pdbsum/2z71 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [http://www.ebi.ac.uk/pdbsum/2z71 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PAC_BACSH PAC_BACSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 25:		Line 27:
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
	[[Category: Penicillin amidase]]		[[Category: Penicillin amidase]]
-	[[Category: Brannigan, J.]]	+	[[Category: Brannigan, J]]
-	[[Category: Dodson, G G.]]	+	[[Category: Dodson, G G]]
-	[[Category: Pathak, M C.]]	+	[[Category: Pathak, M C]]
-	[[Category: Suresh, C G.]]	+	[[Category: Suresh, C G]]
	[[Category: Antibiotic resistance]]		[[Category: Antibiotic resistance]]
	[[Category: Autoproteolysis]]		[[Category: Autoproteolysis]]

OCA at 05:33, 2 October 2014

2014-10-02T05:33:36Z

←Older revision		Revision as of 05:33, 2 October 2014
Line 1:		Line 1:
-	~~[[Image:2z71.png\|left\|200px]]~~	+	==Structure of truncated mutant CYS1GLY of penicillin V acylase from bacillus sphaericus co-crystallized with penicillin V==
-		+	<StructureSection load='2z71' size='340' side='right' caption='[[2z71]], [[Resolution\|resolution]] 2.60Å' scene=''>
-	~~{{STRUCTURE_2z71\| PDB=2z71 \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2z71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z71 FirstGlance]. <br>
-	===Structure of truncated mutant CYS1GLY of penicillin V acylase from bacillus sphaericus co-crystallized with penicillin V===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNV:(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1-+AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC+ACID'>PNV</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2pva\|2pva]], [[3pva\|3pva]], [[2iwm\|2iwm]], [[2quy\|2quy]]</td></tr>
-	~~{{ABSTRACT_PUBMED_018800762}}~~	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
-		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z71 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z71 RCSB], [http://www.ebi.ac.uk/pdbsum/2z71 PDBsum]</span></td></tr>
-	==~~About this Structure~~==	+	<table>
-	[[2z71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA].	+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/2z71_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Penicillin acylase\|Penicillin acylase]]		*[[Penicillin acylase\|Penicillin acylase]]
-		+	__TOC__
-	~~==Reference==~~	+	</StructureSection>
-	~~<ref group="xtra">PMID:018800762</ref>~~<~~references group="xtra"~~/>	+
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
	[[Category: Penicillin amidase]]		[[Category: Penicillin amidase]]

OCA: Protected "2z71" [edit=sysop:move=sysop]

2013-01-07T20:19:48Z

Protected "2z71" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:19, 7 January 2013

OCA at 20:19, 7 January 2013

2013-01-07T20:19:45Z

←Older revision		Revision as of 20:19, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2z71.png\|left\|200px]]		[[Image:2z71.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2z71", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2z71\| PDB=2z71 \| SCENE= }}		{{STRUCTURE_2z71\| PDB=2z71 \| SCENE= }}

	===Structure of truncated mutant CYS1GLY of penicillin V acylase from bacillus sphaericus co-crystallized with penicillin V===		===Structure of truncated mutant CYS1GLY of penicillin V acylase from bacillus sphaericus co-crystallized with penicillin V===

		+	{{ABSTRACT_PUBMED_018800762}}

	==About this Structure==		==About this Structure==
-	~~2Z71~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA].	+	[[2z71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA].
		+
		+	==See Also==
		+	*[[Penicillin acylase\|Penicillin acylase]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:018800762</ref><references group="xtra"/>
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
	[[Category: Penicillin amidase]]		[[Category: Penicillin amidase]]
Line 29:		Line 29:
	[[Category: Precursor]]		[[Category: Precursor]]
	[[Category: Zymogen]]		[[Category: Zymogen]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:36:56 2009''

OCA at 04:36, 17 February 2009

2009-02-17T04:36:58Z

←Older revision		Revision as of 04:36, 17 February 2009
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:2z71.~~jpg~~\|left\|200px]]	+	[[Image:2z71.png\|left\|200px]]

	<!--		<!--
Line 14:		Line 14:

	==About this Structure==		==About this Structure==
-	2Z71 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA].	+	2Z71 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z71 OCA].
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
	[[Category: Penicillin amidase]]		[[Category: Penicillin amidase]]
-	[[Category: Single protein]]
	[[Category: Brannigan, J.]]		[[Category: Brannigan, J.]]
	[[Category: Dodson, G G.]]		[[Category: Dodson, G G.]]
Line 31:		Line 30:
	[[Category: Zymogen]]		[[Category: Zymogen]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Aug 27 11~~:14:~~23 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:36:56 2009''