2zfj - Revision history

OCA at 13:35, 1 November 2023

2023-11-01T13:35:07Z

←Older revision		Revision as of 13:35, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='2zfj' size='340' side='right'caption='[[2zfj]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='2zfj' size='340' side='right'caption='[[2zfj]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zfj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZFJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zfj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZFJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ADP:ADENOSINE~~-~~5-DIPHOSPHATE'>ADP</scene>~~, ~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[1vfv\|1vfv]]~~, ~~[[1vfw\|1vfw]], [[1vfx\|1vfx]], [[1vfz\|1vfz]], [[1i6i\|1i6i]], [[1i5s\|1i5s]], [[2zfi\|2zfi]], [[2zfk\|2zfk]], [[2zfl\|2zfl]], [[2zfm\|2zfm]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfj OCA], [https://pdbe.org/2zfj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zfj RCSB], [https://www.ebi.ac.uk/pdbsum/2zfj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zfj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfj OCA], [https://pdbe.org/2zfj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zfj RCSB], [https://www.ebi.ac.uk/pdbsum/2zfj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zfj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/KIF1A_MOUSE KIF1A_MOUSE]] Motor for anterograde axonal transport of synaptic vesicle precursors.	+	[https://www.uniprot.org/uniprot/KIF1A_MOUSE KIF1A_MOUSE] Motor for anterograde axonal transport of synaptic vesicle precursors.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Hirokawa, N]]	+	[[Category: Hirokawa N]]
-	[[Category: Nitta, R]]	+	[[Category: Nitta R]]
-	[[Category: Okada, Y]]	+	[[Category: Okada Y]]
-	~~[[Category: Alpha and beta protein]]~~	+
-	~~[[Category: Atp-binding]]~~	+
-	~~[[Category: Atpase]]~~	+
-	~~[[Category: Coiled coil]]~~	+
-	~~[[Category: Enzyme]]~~	+
-	~~[[Category: Kinesin]]~~	+
-	~~[[Category: Microtubule]]~~	+
-	~~[[Category: Motor protein]]~~	+
-	~~[[Category: Nucleotide-binding]]~~	+
-	~~[[Category: P-loop]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 10:51, 8 December 2021

2021-12-08T10:51:56Z

←Older revision		Revision as of 10:51, 8 December 2021
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	<StructureSection load='2zfj' size='340' side='right'caption='[[2zfj]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='2zfj' size='340' side='right'caption='[[2zfj]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zfj]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ZFJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zfj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZFJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vfv\|1vfv]], [[1vfw\|1vfw]], [[1vfx\|1vfx]], [[1vfz\|1vfz]], [[1i6i\|1i6i]], [[1i5s\|1i5s]], [[2zfi\|2zfi]], [[2zfk\|2zfk]], [[2zfl\|2zfl]], [[2zfm\|2zfm]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1vfv\|1vfv]], [[1vfw\|1vfw]], [[1vfx\|1vfx]], [[1vfz\|1vfz]], [[1i6i\|1i6i]], [[1i5s\|1i5s]], [[2zfi\|2zfi]], [[2zfk\|2zfk]], [[2zfl\|2zfl]], [[2zfm\|2zfm]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfj OCA], [~~http~~://pdbe.org/2zfj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2zfj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2zfj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2zfj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfj OCA], [https://pdbe.org/2zfj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zfj RCSB], [https://www.ebi.ac.uk/pdbsum/2zfj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zfj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/KIF1A_MOUSE KIF1A_MOUSE]] Motor for anterograde axonal transport of synaptic vesicle precursors.	+	[[https://www.uniprot.org/uniprot/KIF1A_MOUSE KIF1A_MOUSE]] Motor for anterograde axonal transport of synaptic vesicle precursors.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Kinesin\|Kinesin]]	+	*[[Kinesin 3D Structures\|Kinesin 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:24, 21 August 2019

2019-08-21T07:24:57Z

←Older revision		Revision as of 07:24, 21 August 2019
Line 1:		Line 1:

	==Crystal Structure of the Kif1A Motor Domain during Mg release: Mg-releasing Transition-1==		==Crystal Structure of the Kif1A Motor Domain during Mg release: Mg-releasing Transition-1==
-	<StructureSection load='2zfj' size='340' side='right' caption='[[2zfj]], [[Resolution\|resolution]] 3.20Å' scene=''>	+	<StructureSection load='2zfj' size='340' side='right'caption='[[2zfj]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2zfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZFJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2zfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZFJ FirstGlance]. <br>
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zf/2zfj_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zf/2zfj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 2zfj" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2zfj" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Kinesin\|Kinesin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Hirokawa, N]]		[[Category: Hirokawa, N]]

OCA at 21:41, 15 November 2017

2017-11-15T21:41:26Z

←Older revision		Revision as of 21:41, 15 November 2017
Line 1:		Line 1:
		+
	==Crystal Structure of the Kif1A Motor Domain during Mg release: Mg-releasing Transition-1==		==Crystal Structure of the Kif1A Motor Domain during Mg release: Mg-releasing Transition-1==
	<StructureSection load='2zfj' size='340' side='right' caption='[[2zfj]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='2zfj' size='340' side='right' caption='[[2zfj]], [[Resolution\|resolution]] 3.20Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vfv\|1vfv]], [[1vfw\|1vfw]], [[1vfx\|1vfx]], [[1vfz\|1vfz]], [[1i6i\|1i6i]], [[1i5s\|1i5s]], [[2zfi\|2zfi]], [[2zfk\|2zfk]], [[2zfl\|2zfl]], [[2zfm\|2zfm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vfv\|1vfv]], [[1vfw\|1vfw]], [[1vfx\|1vfx]], [[1vfz\|1vfz]], [[1i6i\|1i6i]], [[1i5s\|1i5s]], [[2zfi\|2zfi]], [[2zfk\|2zfk]], [[2zfl\|2zfl]], [[2zfm\|2zfm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfj OCA], [http://pdbe.org/2zfj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zfj RCSB], [http://www.ebi.ac.uk/pdbsum/2zfj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfj OCA], [http://pdbe.org/2zfj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zfj RCSB], [http://www.ebi.ac.uk/pdbsum/2zfj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zfj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 2zfj" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2zfj" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Kinesin\|Kinesin]]
	== References ==		== References ==
	<references/>		<references/>
Line 42:		Line 40:
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Atpase]]		[[Category: Atpase]]
		+	[[Category: Coiled coil]]
	[[Category: Enzyme]]		[[Category: Enzyme]]
	[[Category: Kinesin]]		[[Category: Kinesin]]

OCA at 04:45, 7 February 2016

2016-02-07T04:45:50Z

←Older revision		Revision as of 04:45, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='2zfj' size='340' side='right' caption='[[2zfj]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='2zfj' size='340' side='right' caption='[[2zfj]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZFJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZFJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vfv\|1vfv]], [[1vfw\|1vfw]], [[1vfx\|1vfx]], [[1vfz\|1vfz]], [[1i6i\|1i6i]], [[1i5s\|1i5s]], [[2zfi\|2zfi]], [[2zfk\|2zfk]], [[2zfl\|2zfl]], [[2zfm\|2zfm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vfv\|1vfv]], [[1vfw\|1vfw]], [[1vfx\|1vfx]], [[1vfz\|1vfz]], [[1i6i\|1i6i]], [[1i5s\|1i5s]], [[2zfi\|2zfi]], [[2zfk\|2zfk]], [[2zfl\|2zfl]], [[2zfm\|2zfm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zfj RCSB], [http://www.ebi.ac.uk/pdbsum/2zfj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfj OCA], [http://pdbe.org/2zfj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zfj RCSB], [http://www.ebi.ac.uk/pdbsum/2zfj PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zfj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2zfj" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Hirokawa, N]]		[[Category: Hirokawa, N]]
	[[Category: Nitta, R]]		[[Category: Nitta, R]]

OCA at 07:57, 24 December 2014

2014-12-24T07:57:20Z

←Older revision		Revision as of 07:57, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2zfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZFJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2zfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZFJ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vfv\|1vfv]], [[1vfw\|1vfw]], [[1vfx\|1vfx]], [[1vfz\|1vfz]], [[1i6i\|1i6i]], [[1i5s\|1i5s]], [[2zfi\|2zfi]], [[2zfk\|2zfk]], [[2zfl\|2zfl]], [[2zfm\|2zfm]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vfv\|1vfv]], [[1vfw\|1vfw]], [[1vfx\|1vfx]], [[1vfz\|1vfz]], [[1i6i\|1i6i]], [[1i5s\|1i5s]], [[2zfi\|2zfi]], [[2zfk\|2zfk]], [[2zfl\|2zfl]], [[2zfm\|2zfm]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zfj RCSB], [http://www.ebi.ac.uk/pdbsum/2zfj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zfj RCSB], [http://www.ebi.ac.uk/pdbsum/2zfj PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/KIF1A_MOUSE KIF1A_MOUSE]] Motor for anterograde axonal transport of synaptic vesicle precursors.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Hirokawa, N.]]	+	[[Category: Hirokawa, N]]
-	[[Category: Nitta, R.]]	+	[[Category: Nitta, R]]
-	[[Category: Okada, Y.]]	+	[[Category: Okada, Y]]
	[[Category: Alpha and beta protein]]		[[Category: Alpha and beta protein]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]

OCA at 07:45, 29 September 2014

2014-09-29T07:45:37Z

←Older revision		Revision as of 07:45, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2zfj.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of the Kif1A Motor Domain during Mg release: Mg-releasing Transition-1==
		+	<StructureSection load='2zfj' size='340' side='right' caption='[[2zfj]], [[Resolution\|resolution]] 3.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2zfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZFJ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vfv\|1vfv]], [[1vfw\|1vfw]], [[1vfx\|1vfx]], [[1vfz\|1vfz]], [[1i6i\|1i6i]], [[1i5s\|1i5s]], [[2zfi\|2zfi]], [[2zfk\|2zfk]], [[2zfl\|2zfl]], [[2zfm\|2zfm]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zfj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zfj RCSB], [http://www.ebi.ac.uk/pdbsum/2zfj PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zf/2zfj_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Mg-ADP release is considered to be a crucial process for the regulation and motility of kinesin. To gain insight into the structural basis of this process, we solved the atomic structures of kinesin superfamily protein-1A (KIF1A) during and after Mg(2+) release. On the basis of new structural and mutagenesis data, we propose a model mechanism for microtubule activation of Mg-ADP release from KIF1A. In our model, a specific interaction between loop L7 of KIF1A and beta-tubulin reconfigures the KIF1A active site by shifting the relative positions of switches I and II. This leads to the sequential release of a group of water molecules that sits over the Mg(2+) in the active site, followed by Mg(2+) and finally the ADP. We further propose that this set of events is linked to a strain-dependent docking of the neck linker to the motor core, which produces a two-step power stroke.

-	~~{{STRUCTURE_2zfj\| PDB=2zfj \| SCENE= }}~~	+	Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin.,Nitta R, Okada Y, Hirokawa N Nat Struct Mol Biol. 2008 Oct;15(10):1067-75. Epub 2008 Sep 21. PMID:18806800<ref>PMID:18806800</ref>

-	~~===Crystal Structure~~ of the ~~Kif1A Motor Domain during Mg release: Mg-releasing Transition-1===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18806800}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2zfj]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mus_musculus Mus musculus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA].~~	+

	==See Also==		==See Also==
	*[[Kinesin\|Kinesin]]		*[[Kinesin\|Kinesin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:018806800<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Hirokawa, N.]]		[[Category: Hirokawa, N.]]

OCA at 05:36, 20 October 2012

2012-10-20T05:36:44Z

←Older revision		Revision as of 05:36, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2zfj]] is a 1 chain structure ~~of [[Kinesin]]~~ with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA].	+	[[2zfj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZFJ OCA].

	==See Also==		==See Also==

OCA at 10:37, 25 July 2012

2012-07-25T10:37:41Z

←Older revision		Revision as of 10:37, 25 July 2012
Line 1:		Line 1:
	[[Image:2zfj.png\|left\|200px]]		[[Image:2zfj.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2zfj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2zfj\| PDB=2zfj \| SCENE= }}		{{STRUCTURE_2zfj\| PDB=2zfj \| SCENE= }}

	===Crystal Structure of the Kif1A Motor Domain during Mg release: Mg-releasing Transition-1===		===Crystal Structure of the Kif1A Motor Domain during Mg release: Mg-releasing Transition-1===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18806800}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18806800 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18806800}}		{{ABSTRACT_PUBMED_18806800}}

Line 22:		Line 11:

	==See Also==		==See Also==
-	*[[Kinesin]]	+	*[[Kinesin\|Kinesin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18806800~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018806800</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Hirokawa, N.]]		[[Category: Hirokawa, N.]]
Line 33:		Line 22:
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Atpase]]		[[Category: Atpase]]
-	[[Category: Coiled coil]]
	[[Category: Enzyme]]		[[Category: Enzyme]]
	[[Category: Kinesin]]		[[Category: Kinesin]]

OCA: Protected "2zfj" [edit=sysop:move=sysop]

2010-12-26T20:04:16Z

Protected "2zfj" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:04, 26 December 2010