2zlw - Revision history

OCA at 13:42, 1 November 2023

2023-11-01T13:42:38Z

←Older revision		Revision as of 13:42, 1 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2zlw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZLW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2zlw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZLW FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1y8k\|1y8k]], [[1y8i\|1y8i]], [[1y8h\|1y8h]], [[1lfq\|1lfq]], [[1jy7\|1jy7]], [[1lfl\|1lfl]], [[2zlt\|2zlt]], [[2zlu\|2zlu]], [[2zlv\|2zlv]], [[2zlx\|2zlx]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlw OCA], [https://pdbe.org/2zlw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zlw RCSB], [https://www.ebi.ac.uk/pdbsum/2zlw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zlw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlw OCA], [https://pdbe.org/2zlw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zlw RCSB], [https://www.ebi.ac.uk/pdbsum/2zlw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zlw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/HBA_HORSE HBA_HORSE~~]] Involved in oxygen transport from the lung to the various peripheral tissues. [[https://www.uniprot.org/uniprot/HBB_HORSE HBB_HORSE]~~] Involved in oxygen transport from the lung to the various peripheral tissues.	+	[https://www.uniprot.org/uniprot/HBA_HORSE HBA_HORSE] Involved in oxygen transport from the lung to the various peripheral tissues.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Equus caballus]]		[[Category: Equus caballus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kaushal~~, P S~~]]	+	[[Category: Kaushal PS]]
-	[[Category: Sankaranarayanan, R]]	+	[[Category: Sankaranarayanan R]]
-	[[Category: Vijayan, M]]	+	[[Category: Vijayan M]]
-	~~[[Category: Allosteric transition]]~~	+
-	~~[[Category: Heme]]~~	+
-	~~[[Category: Iron]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Oxygen storage]]~~	+
-	~~[[Category: Oxygen transport]]~~	+
-	~~[[Category: Polymorphism]]~~	+
-	~~[[Category: Protein hydration]]~~	+
-	~~[[Category: Solvent content and crystal structure]]~~	+
-	~~[[Category: Transport]]~~	+
-	~~[[Category: Variability in quaternary structure]]~~	+
-	~~[[Category: Water-mediated transformation~~]]	+

OCA at 17:32, 15 December 2021

2021-12-15T17:32:35Z

←Older revision		Revision as of 17:32, 15 December 2021
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	<StructureSection load='2zlw' size='340' side='right'caption='[[2zlw]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2zlw' size='340' side='right'caption='[[2zlw]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zlw]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ZLW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zlw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZLW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1y8k\|1y8k]], [[1y8i\|1y8i]], [[1y8h\|1y8h]], [[1lfq\|1lfq]], [[1jy7\|1jy7]], [[1lfl\|1lfl]], [[2zlt\|2zlt]], [[2zlu\|2zlu]], [[2zlv\|2zlv]], [[2zlx\|2zlx]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1y8k\|1y8k]], [[1y8i\|1y8i]], [[1y8h\|1y8h]], [[1lfq\|1lfq]], [[1jy7\|1jy7]], [[1lfl\|1lfl]], [[2zlt\|2zlt]], [[2zlu\|2zlu]], [[2zlv\|2zlv]], [[2zlx\|2zlx]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2zlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlw OCA], [~~http~~://pdbe.org/2zlw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2zlw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2zlw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2zlw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlw OCA], [https://pdbe.org/2zlw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zlw RCSB], [https://www.ebi.ac.uk/pdbsum/2zlw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zlw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HBA_HORSE HBA_HORSE]] Involved in oxygen transport from the lung to the various peripheral tissues. [[~~http~~://www.uniprot.org/uniprot/HBB_HORSE HBB_HORSE]] Involved in oxygen transport from the lung to the various peripheral tissues.	+	[[https://www.uniprot.org/uniprot/HBA_HORSE HBA_HORSE]] Involved in oxygen transport from the lung to the various peripheral tissues. [[https://www.uniprot.org/uniprot/HBB_HORSE HBB_HORSE]] Involved in oxygen transport from the lung to the various peripheral tissues.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:07, 18 December 2019

2019-12-18T08:07:23Z

←Older revision		Revision as of 08:07, 18 December 2019
Line 1:		Line 1:

	==Horse methemoglobin high salt, pH 7.0 (75% relative humidity)==		==Horse methemoglobin high salt, pH 7.0 (75% relative humidity)==
-	<StructureSection load='2zlw' size='340' side='right' caption='[[2zlw]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='2zlw' size='340' side='right'caption='[[2zlw]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2zlw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZLW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2zlw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZLW FirstGlance]. <br>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Equus caballus]]		[[Category: Equus caballus]]
		+	[[Category: Large Structures]]
	[[Category: Kaushal, P S]]		[[Category: Kaushal, P S]]
	[[Category: Sankaranarayanan, R]]		[[Category: Sankaranarayanan, R]]

OCA at 06:51, 18 October 2018

2018-10-18T06:51:22Z

←Older revision		Revision as of 06:51, 18 October 2018
Line 1:		Line 1:
		+
	==Horse methemoglobin high salt, pH 7.0 (75% relative humidity)==		==Horse methemoglobin high salt, pH 7.0 (75% relative humidity)==
	<StructureSection load='2zlw' size='340' side='right' caption='[[2zlw]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2zlw' size='340' side='right' caption='[[2zlw]], [[Resolution\|resolution]] 2.90Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1y8k\|1y8k]], [[1y8i\|1y8i]], [[1y8h\|1y8h]], [[1lfq\|1lfq]], [[1jy7\|1jy7]], [[1lfl\|1lfl]], [[2zlt\|2zlt]], [[2zlu\|2zlu]], [[2zlv\|2zlv]], [[2zlx\|2zlx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1y8k\|1y8k]], [[1y8i\|1y8i]], [[1y8h\|1y8h]], [[1lfq\|1lfq]], [[1jy7\|1jy7]], [[1lfl\|1lfl]], [[2zlt\|2zlt]], [[2zlu\|2zlu]], [[2zlv\|2zlv]], [[2zlx\|2zlx]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlw OCA], [http://pdbe.org/2zlw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zlw RCSB], [http://www.ebi.ac.uk/pdbsum/2zlw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlw OCA], [http://pdbe.org/2zlw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zlw RCSB], [http://www.ebi.ac.uk/pdbsum/2zlw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zlw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zl/2zlw_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zl/2zlw_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 45:		Line 46:
	[[Category: Oxygen storage]]		[[Category: Oxygen storage]]
	[[Category: Oxygen transport]]		[[Category: Oxygen transport]]
		+	[[Category: Polymorphism]]
	[[Category: Protein hydration]]		[[Category: Protein hydration]]
	[[Category: Solvent content and crystal structure]]		[[Category: Solvent content and crystal structure]]

OCA at 06:09, 7 February 2016

2016-02-07T06:09:32Z

←Older revision		Revision as of 06:09, 7 February 2016
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1y8k\|1y8k]], [[1y8i\|1y8i]], [[1y8h\|1y8h]], [[1lfq\|1lfq]], [[1jy7\|1jy7]], [[1lfl\|1lfl]], [[2zlt\|2zlt]], [[2zlu\|2zlu]], [[2zlv\|2zlv]], [[2zlx\|2zlx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1y8k\|1y8k]], [[1y8i\|1y8i]], [[1y8h\|1y8h]], [[1lfq\|1lfq]], [[1jy7\|1jy7]], [[1lfl\|1lfl]], [[2zlt\|2zlt]], [[2zlu\|2zlu]], [[2zlv\|2zlv]], [[2zlx\|2zlx]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zlw RCSB], [http://www.ebi.ac.uk/pdbsum/2zlw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlw OCA], [http://pdbe.org/2zlw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zlw RCSB], [http://www.ebi.ac.uk/pdbsum/2zlw PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zlw ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2zlw" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 08:31, 24 December 2014

2014-12-24T08:31:18Z

←Older revision		Revision as of 08:31, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2zlw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZLW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2zlw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZLW FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1y8k\|1y8k]], [[1y8i\|1y8i]], [[1y8h\|1y8h]], [[1lfq\|1lfq]], [[1jy7\|1jy7]], [[1lfl\|1lfl]], [[2zlt\|2zlt]], [[2zlu\|2zlu]], [[2zlv\|2zlv]], [[2zlx\|2zlx]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1y8k\|1y8k]], [[1y8i\|1y8i]], [[1y8h\|1y8h]], [[1lfq\|1lfq]], [[1jy7\|1jy7]], [[1lfl\|1lfl]], [[2zlt\|2zlt]], [[2zlu\|2zlu]], [[2zlv\|2zlv]], [[2zlx\|2zlx]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zlw RCSB], [http://www.ebi.ac.uk/pdbsum/2zlw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zlw RCSB], [http://www.ebi.ac.uk/pdbsum/2zlw PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HBA_HORSE HBA_HORSE]] Involved in oxygen transport from the lung to the various peripheral tissues. [[http://www.uniprot.org/uniprot/HBB_HORSE HBB_HORSE]] Involved in oxygen transport from the lung to the various peripheral tissues.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Equus caballus]]		[[Category: Equus caballus]]
-	[[Category: Kaushal, P S.]]	+	[[Category: Kaushal, P S]]
-	[[Category: Sankaranarayanan, R.]]	+	[[Category: Sankaranarayanan, R]]
-	[[Category: Vijayan, M.]]	+	[[Category: Vijayan, M]]
	[[Category: Allosteric transition]]		[[Category: Allosteric transition]]
	[[Category: Heme]]		[[Category: Heme]]

OCA at 08:22, 29 September 2014

2014-09-29T08:22:42Z

←Older revision		Revision as of 08:22, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2zlw.~~png~~\|~~left~~\|200px]]	+	==Horse methemoglobin high salt, pH 7.0 (75% relative humidity)==
		+	<StructureSection load='2zlw' size='340' side='right' caption='[[2zlw]], [[Resolution\|resolution]] 2.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2zlw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZLW FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1y8k\|1y8k]], [[1y8i\|1y8i]], [[1y8h\|1y8h]], [[1lfq\|1lfq]], [[1jy7\|1jy7]], [[1lfl\|1lfl]], [[2zlt\|2zlt]], [[2zlu\|2zlu]], [[2zlv\|2zlv]], [[2zlx\|2zlx]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zlw RCSB], [http://www.ebi.ac.uk/pdbsum/2zlw PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zl/2zlw_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structure of high-salt horse methaemoglobin has been determined at environmental relative humidities (r.h.) of 88, 79, 75 and 66%. The molecule is in the R state in the native and the r.h. 88% crystals. At r.h. 79%, the water content of the crystal is reduced and the molecule appears to move towards the R2 state. The crystals undergo a water-mediated transformation involving a doubling of one of the unit-cell parameters and an increase in water content when the environmental humidity is further reduced to r.h. 75%. The water content is now similar to that in the native crystals and the molecules are in the R state. The crystal structure at r.h. 66% is similar, but not identical, to that at r.h. 75%, but the solvent content is substantially reduced and the molecules have a quaternary structure that is in between those corresponding to the R and R2 states. Thus, variation in hydration leads to variation in the quaternary structure. Furthermore, partial dehydration appears to shift the structure from the R state to the R2 state. This observation is in agreement with the earlier conclusion that the changes in protein structure that accompany partial dehydration are similar to those that occur during protein action.

-	~~{{STRUCTURE_2zlw\| PDB=2zlw \| SCENE= }}~~	+	Water-mediated variability in the structure of relaxed-state haemoglobin.,Kaushal PS, Sankaranarayanan R, Vijayan M Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jun 1;64(Pt, 6):463-9. Epub 2008 May 17. PMID:18540052<ref>PMID:18540052</ref>

-	~~===Horse methemoglobin high salt~~, ~~pH 7.0 (75% relative humidity)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18540052}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2zlw]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Equus_caballus Equus caballus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA].~~	+

	==See Also==		==See Also==
-	*[[Hemoglobin\|Hemoglobin]]	+	*[[Hemoglobin 3D structures\|Hemoglobin 3D structures]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:018540052<~~/~~ref~~><~~ref group="xtra">PMID:015887226</ref><ref group="xtra">PMID:012077435</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Equus caballus]]		[[Category: Equus caballus]]
	[[Category: Kaushal, P S.]]		[[Category: Kaushal, P S.]]

OCA at 05:48, 20 October 2012

2012-10-20T05:48:33Z

←Older revision		Revision as of 05:48, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2zlw]] is a 4 chain structure ~~of [[Hemoglobin]]~~ with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA].	+	[[2zlw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLW OCA].

	==See Also==		==See Also==

OCA at 11:11, 25 July 2012

2012-07-25T11:11:49Z

←Older revision		Revision as of 11:11, 25 July 2012
Line 1:		Line 1:
	[[Image:2zlw.png\|left\|200px]]		[[Image:2zlw.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2zlw", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2zlw\| PDB=2zlw \| SCENE= }}		{{STRUCTURE_2zlw\| PDB=2zlw \| SCENE= }}

	===Horse methemoglobin high salt, pH 7.0 (75% relative humidity)===		===Horse methemoglobin high salt, pH 7.0 (75% relative humidity)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18540052}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18540052 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18540052}}		{{ABSTRACT_PUBMED_18540052}}

Line 22:		Line 11:

	==See Also==		==See Also==
-	*[[Hemoglobin]]	+	*[[Hemoglobin\|Hemoglobin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18540052~~</ref><ref group="xtra">PMID:~~15887226~~</ref><ref group="xtra">PMID:~~12077435~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018540052</ref><ref group="xtra">PMID:015887226</ref><ref group="xtra">PMID:012077435</ref><references group="xtra"/>
	[[Category: Equus caballus]]		[[Category: Equus caballus]]
	[[Category: Kaushal, P S.]]		[[Category: Kaushal, P S.]]
Line 36:		Line 25:
	[[Category: Oxygen storage]]		[[Category: Oxygen storage]]
	[[Category: Oxygen transport]]		[[Category: Oxygen transport]]
-	[[Category: Polymorphism]]
	[[Category: Protein hydration]]		[[Category: Protein hydration]]
	[[Category: Solvent content and crystal structure]]		[[Category: Solvent content and crystal structure]]

OCA: Protected "2zlw" [edit=sysop:move=sysop]

2011-03-14T21:25:45Z

Protected "2zlw" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:25, 14 March 2011