333d - Revision history

OCA at 08:39, 7 February 2024

2024-02-07T08:39:12Z

←Older revision		Revision as of 08:39, 7 February 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[333d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=333D FirstGlance]. <br>		<table><tr><td colspan='2'>[[333d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=333D FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.52Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=I:~~INOSINIC~~+~~ACID~~'>I</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [https://pdbe.org/333d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=333d RCSB], [https://www.ebi.ac.uk/pdbsum/333d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=333d ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [https://pdbe.org/333d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=333d RCSB], [https://www.ebi.ac.uk/pdbsum/333d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=333d ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The X-ray crystallographic structure of the RNA duplex [r(CGCAIGCG)]2 has been refined to 2.5 A. It shows a symmetric internal loop of two non-Watson-Crick base pairs which form in the middle of the duplex. The tandem A-I/I-A pairs are related by a crystallographic two-fold axis. Both A(anti)-I(anti) mismatches are in a head-to-head conformation forming hydrogen bonds using the Watson-Crick positions. The octamer duplexes stack above one another in the cell forming a pseudo-infinite helix throughout the crystal. A hydrated calcium ion bridges between the 3'-terminal of one molecule and the backbone of another. The tandem A-I mismatches are incorporated with only minor distortion to the backbone. This is in contrast to the large helical perturbations often produced by sheared G-A pairs in RNA oligonucleotides.
-
-	The crystal structure of an RNA oligomer incorporating tandem adenosine-inosine mismatches.,Carter RJ, Baeyens KJ, SantaLucia J, Turner DH, Holbrook SR Nucleic Acids Res. 1997 Oct 15;25(20):4117-22. PMID:9321667<ref>PMID:9321667</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 333d" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Baeyens~~, K J~~]]	+	[[Category: Baeyens KJ]]
-	[[Category: Carter~~, R J~~]]	+	[[Category: Carter RJ]]
-	[[Category: Holbrook~~, S R~~]]	+	[[Category: Holbrook SR]]
-	[[Category: SantaLucia, J]]	+	[[Category: SantaLucia Jr J]]
-	[[Category: Turner~~, D H]]~~	+	[[Category: Turner DH]]
-	~~[[Category: A-rna]]~~	+
-	~~[[Category: Double helix]]~~	+
-	~~[[Category: Internal loop]]~~	+
-	~~[[Category: Mismatched]]~~	+
-	~~[[Category: Rna~~]]	+

OCA at 13:23, 4 May 2022

2022-05-04T13:23:53Z

←Older revision		Revision as of 13:23, 4 May 2022
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	<StructureSection load='333d' size='340' side='right'caption='[[333d]], [[Resolution\|resolution]] 2.52Å' scene=''>		<StructureSection load='333d' size='340' side='right'caption='[[333d]], [[Resolution\|resolution]] 2.52Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[333d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=333D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[333d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=333D FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=I:INOSINIC+ACID'>I</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=I:INOSINIC+ACID'>I</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [~~http~~://pdbe.org/333d PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=333d RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/333d PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=333d ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [https://pdbe.org/333d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=333d RCSB], [https://www.ebi.ac.uk/pdbsum/333d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=333d ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:13, 29 July 2020

2020-07-29T12:13:33Z

←Older revision		Revision as of 12:13, 29 July 2020
Line 1:		Line 1:

	==THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES==		==THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES==
-	<StructureSection load='333d' size='340' side='right' caption='[[333d]], [[Resolution\|resolution]] 2.52Å' scene=''>	+	<StructureSection load='333d' size='340' side='right'caption='[[333d]], [[Resolution\|resolution]] 2.52Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[333d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=333D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[333d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=333D FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=I:INOSINIC+ACID'>I</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=I:INOSINIC+ACID'>I</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [http://pdbe.org/333d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=333d RCSB], [http://www.ebi.ac.uk/pdbsum/333d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=333d ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [http://pdbe.org/333d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=333d RCSB], [http://www.ebi.ac.uk/pdbsum/333d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=333d ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Baeyens, K J]]		[[Category: Baeyens, K J]]
	[[Category: Carter, R J]]		[[Category: Carter, R J]]

OCA at 19:54, 11 August 2016

2016-08-11T19:54:50Z

←Older revision		Revision as of 19:54, 11 August 2016
Line 1:		Line 1:
		+
	==THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES==		==THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES==
	<StructureSection load='333d' size='340' side='right' caption='[[333d]], [[Resolution\|resolution]] 2.52Å' scene=''>		<StructureSection load='333d' size='340' side='right' caption='[[333d]], [[Resolution\|resolution]] 2.52Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=I:INOSINIC+ACID'>I</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=I:INOSINIC+ACID'>I</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=333d RCSB], [http://www.ebi.ac.uk/pdbsum/333d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [http://pdbe.org/333d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=333d RCSB], [http://www.ebi.ac.uk/pdbsum/333d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=333d ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 333d" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:22, 20 January 2015

2015-01-20T10:22:02Z

←Older revision		Revision as of 10:22, 20 January 2015
Line 1:		Line 1:
-	[[~~Image:~~333d.~~png~~\|~~left~~\|~~200px~~]]	+	==THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES==
		+	<StructureSection load='333d' size='340' side='right' caption='[[333d]], [[Resolution\|resolution]] 2.52Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[333d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=333D FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=I:INOSINIC+ACID'>I</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=333d RCSB], [http://www.ebi.ac.uk/pdbsum/333d PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The X-ray crystallographic structure of the RNA duplex [r(CGCAIGCG)]2 has been refined to 2.5 A. It shows a symmetric internal loop of two non-Watson-Crick base pairs which form in the middle of the duplex. The tandem A-I/I-A pairs are related by a crystallographic two-fold axis. Both A(anti)-I(anti) mismatches are in a head-to-head conformation forming hydrogen bonds using the Watson-Crick positions. The octamer duplexes stack above one another in the cell forming a pseudo-infinite helix throughout the crystal. A hydrated calcium ion bridges between the 3'-terminal of one molecule and the backbone of another. The tandem A-I mismatches are incorporated with only minor distortion to the backbone. This is in contrast to the large helical perturbations often produced by sheared G-A pairs in RNA oligonucleotides.

-	~~{{STRUCTURE_333d\| PDB=333d \| SCENE= }}~~	+	The crystal structure of an RNA oligomer incorporating tandem adenosine-inosine mismatches.,Carter RJ, Baeyens KJ, SantaLucia J, Turner DH, Holbrook SR Nucleic Acids Res. 1997 Oct 15;25(20):4117-22. PMID:9321667<ref>PMID:9321667</ref>

-	~~===THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_9321667}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[333d]] is a 1 chain structure. Full crystallographic information is available from [http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA].~~	+	</StructureSection>
-	[[Category: Baeyens, K J.]]	+	[[Category: Baeyens, K J]]
-	[[Category: Carter, R J.]]	+	[[Category: Carter, R J]]
-	[[Category: Holbrook, S R.]]	+	[[Category: Holbrook, S R]]
-	[[Category: SantaLucia, J.]]	+	[[Category: SantaLucia, J]]
-	[[Category: Turner, D H.]]	+	[[Category: Turner, D H]]
	[[Category: A-rna]]		[[Category: A-rna]]
	[[Category: Double helix]]		[[Category: Double helix]]

OCA: Protected "333d" [edit=sysop:move=sysop]

2013-01-07T22:07:24Z

Protected "333d" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:07, 7 January 2013

OCA at 22:07, 7 January 2013

2013-01-07T22:07:21Z

←Older revision		Revision as of 22:07, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:333d.png\|left\|200px]]		[[Image:333d.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_333d", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_333d\| PDB=333d \| SCENE= }}		{{STRUCTURE_333d\| PDB=333d \| SCENE= }}

	===THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES===		===THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_9321667}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 9321667 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_9321667}}		{{ABSTRACT_PUBMED_9321667}}

	==About this Structure==		==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA].	+	[[333d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA].
-		+
-	~~==Reference==~~	+
-	The crystal structure of an RNA oligomer incorporating tandem adenosine-inosine mismatches., Carter RJ, Baeyens KJ, SantaLucia J, Turner DH, Holbrook SR, Nucleic Acids Res. 1997 Oct 15;25(20):4117-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9321667 9321667]	+
	[[Category: Baeyens, K J.]]		[[Category: Baeyens, K J.]]
	[[Category: Carter, R J.]]		[[Category: Carter, R J.]]
	[[Category: Holbrook, S R.]]		[[Category: Holbrook, S R.]]
-	[[Category: ~~Jr.~~, J ~~SantaLucia~~.]]	+	[[Category: SantaLucia, J.]]
	[[Category: Turner, D H.]]		[[Category: Turner, D H.]]
	[[Category: A-rna]]		[[Category: A-rna]]
Line 33:		Line 18:
	[[Category: Internal loop]]		[[Category: Internal loop]]
	[[Category: Mismatched]]		[[Category: Mismatched]]
-		+	[[Category: Rna]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Jul 29 15:29:57 2008''~~	+

OCA at 12:30, 29 July 2008

2008-07-29T12:30:04Z

←Older revision		Revision as of 12:30, 29 July 2008
Line 1:		Line 1:
-	[[Image:333d.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:333d.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_333d\| PDB=333d \| SCENE= }}		{{STRUCTURE_333d\| PDB=333d \| SCENE= }}

-	~~'''~~THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES~~'''~~	+	===THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES===


-	~~==Overview==~~	+	<!--
-	The ~~X-ray crystallographic structure of~~ the ~~RNA duplex [r(CGCAIGCG)]2 has been refined~~ to ~~2.5 A. It shows a symmetric internal loop of two non-Watson-Crick base pairs which form in~~ the ~~middle of the duplex. The tandem A-I~~/~~I-A pairs are related by a crystallographic two-fold axis~~. ~~Both A(anti~~)~~-I(anti) mismatches are in a head-to-head conformation forming hydrogen bonds using~~ the ~~Watson-Crick positions~~. ~~The octamer duplexes stack above one another in the cell forming a pseudo~~-~~infinite helix throughout the crystal. A hydrated calcium ion bridges between the 3'~~-terminal of one molecule and the backbone of another. The tandem A-I mismatches are incorporated with only minor distortion to the backbone. This is in contrast to the large helical perturbations often produced by sheared G-A pairs in RNA oligonucleotides.	+	The line below this paragraph, {{ABSTRACT_PUBMED_9321667}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 9321667 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_9321667}}

	==About this Structure==		==About this Structure==
Line 29:		Line 33:
	[[Category: Internal loop]]		[[Category: Internal loop]]
	[[Category: Mismatched]]		[[Category: Mismatched]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May 4 20~~:16:08 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:29:57 2008''

OCA at 17:16, 4 May 2008

2008-05-04T17:16:08Z

←Older revision		Revision as of 17:16, 4 May 2008
Line 1:		Line 1:
	[[Image:333d.gif\|left\|200px]]		[[Image:333d.gif\|left\|200px]]

-	{{Structure	+	<!--
-	\|PDB~~= 333d \|SIZE=350\|CAPTION= <~~scene ~~name='initialview01'>333d</scene>~~, ~~resolution 2~~.~~520Å~~	+	The line below this paragraph, containing "STRUCTURE_333d", creates the "Structure Box" on the page.
-	~~\|SITE=~~	+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	~~\|LIGAND= <scene name='pdbligand=A:ADENOSINE~~-~~5'~~-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5'-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G:GUANOSINE-5'-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=I:INOSINIC+ACID'>I</scene>	+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	\|~~ACTIVITY~~=	+	or leave the SCENE parameter empty for the default display.
-	\|~~GENE~~=	+	-->
-	~~\|DOMAIN=~~	+	{{STRUCTURE_333d\| PDB=333d \| SCENE= }}
-	~~\|RELATEDENTRY=~~	+
-	\|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [http://www.ebi.ac.uk/pdbsum/333d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=333d RCSB]</span>	+
-	}}	+

	'''THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES'''		'''THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES'''
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	==About this Structure==		==About this Structure==
-	~~333D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ].~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA].	+	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA].

	==Reference==		==Reference==
	The crystal structure of an RNA oligomer incorporating tandem adenosine-inosine mismatches., Carter RJ, Baeyens KJ, SantaLucia J, Turner DH, Holbrook SR, Nucleic Acids Res. 1997 Oct 15;25(20):4117-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9321667 9321667]		The crystal structure of an RNA oligomer incorporating tandem adenosine-inosine mismatches., Carter RJ, Baeyens KJ, SantaLucia J, Turner DH, Holbrook SR, Nucleic Acids Res. 1997 Oct 15;25(20):4117-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9321667 9321667]
-	[[Category: Protein complex]]
	[[Category: Baeyens, K J.]]		[[Category: Baeyens, K J.]]
	[[Category: Carter, R J.]]		[[Category: Carter, R J.]]
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	[[Category: Jr., J SantaLucia.]]		[[Category: Jr., J SantaLucia.]]
	[[Category: Turner, D H.]]		[[Category: Turner, D H.]]
-	[[Category: a-rna]]	+	[[Category: A-rna]]
-	[[Category: ~~double~~ helix]]	+	[[Category: Double helix]]
-	[[Category: ~~internal~~ loop]]	+	[[Category: Internal loop]]
-	[[Category: ~~mismatched~~]]	+	[[Category: Mismatched]]
-		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 20:16:08 2008''
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Mar 31 05~~:21:28 2008''	+

OCA at 02:21, 31 March 2008

2008-03-31T02:21:29Z

←Older revision		Revision as of 02:21, 31 March 2008
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	\|PDB= 333d \|SIZE=350\|CAPTION= <scene name='initialview01'>333d</scene>, resolution 2.520Å		\|PDB= 333d \|SIZE=350\|CAPTION= <scene name='initialview01'>333d</scene>, resolution 2.520Å
	\|SITE=		\|SITE=
-	\|LIGAND= <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>	+	\|LIGAND= <scene name='pdbligand=A:ADENOSINE-5'-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5'-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G:GUANOSINE-5'-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=I:INOSINIC+ACID'>I</scene>
	\|ACTIVITY=		\|ACTIVITY=
	\|GENE=		\|GENE=
		+	\|DOMAIN=
		+	\|RELATEDENTRY=
		+	\|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [http://www.ebi.ac.uk/pdbsum/333d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=333d RCSB]</span>
	}}		}}

Line 26:		Line 29:
	[[Category: Jr., J SantaLucia.]]		[[Category: Jr., J SantaLucia.]]
	[[Category: Turner, D H.]]		[[Category: Turner, D H.]]
-	[[Category: CA]]
	[[Category: a-rna]]		[[Category: a-rna]]
	[[Category: double helix]]		[[Category: double helix]]
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	[[Category: mismatched]]		[[Category: mismatched]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu~~ Mar ~~20 18~~:54:44 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:21:28 2008''