3acx - Revision history

OCA at 10:30, 27 September 2023

2023-09-27T10:30:18Z

←Older revision		Revision as of 10:30, 27 September 2023
Line 3:		Line 3:
	<StructureSection load='3acx' size='340' side='right'caption='[[3acx]], [[Resolution\|resolution]] 1.31Å' scene=''>		<StructureSection load='3acx' size='340' side='right'caption='[[3acx]], [[Resolution\|resolution]] 1.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3acx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus~~ aureus~~" (rosenbach 1884) zopf 1885~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ACX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3acx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ACX FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=673:N-(1-METHYLETHYL)-3~~-[~~(3-PROP-2-EN-1-YLBIPHENYL-4-YL)OXY~~]~~PROPAN-~~1~~-AMINE'>673</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.31Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;'>~~[~~[2zco\|2zco~~]~~], [[2zcp\|2zcp]], [[2zcq\|2zcq]], [[2zcr\|2zcr]], [[2zcs\|2zcs]], [[2zy1\|2zy1]], [[3acw\|3acw]], [[3acy\|3acy]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=673:N-(1-METHYLETHYL)-3-[(3-PROP-2-EN-1-YLBIPHENYL-4-YL)OXY]PROPAN-1-AMINE'>673</scene></td></tr>
-	~~<tr id='gene~~'>~~<td class="sblockLbl"><b>[[Gene\|Gene:]]~~</b>~~</td><td class="sblockDat">CrtM ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3acx OCA], [https://pdbe.org/3acx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3acx RCSB], [https://www.ebi.ac.uk/pdbsum/3acx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3acx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3acx OCA], [https://pdbe.org/3acx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3acx RCSB], [https://www.ebi.ac.uk/pdbsum/3acx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3acx ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CRTM_STAAU CRTM_STAAU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Jeng, W Y~~]]	+	[[Category: Staphylococcus aureus]]
-	[[Category: ~~Liu, C I~~]]	+	[[Category: Jeng WY]]
-	[[Category: ~~Oldfield, E~~]]	+	[[Category: Liu CI]]
-	[[Category: ~~Wang, A H.J~~]]	+	[[Category: Oldfield E]]
-	[[Category: ~~Carotenoid biosynthesis]]~~	+	[[Category: Wang AHJ]]
-	~~[[Category: Crtm]]~~	+
-	~~[[Category: Head-to-head condensation]]~~	+
-	~~[[Category: Inhibitor]]~~	+
-	~~[[Category: Staphyloxanthin biosynthesis]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Transferase-transferase inhibitor complex~~]]	+

OCA at 16:23, 22 December 2021

2021-12-22T16:23:10Z

←Older revision		Revision as of 16:23, 22 December 2021
Line 1:		Line 1:

	==Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673==		==Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673==
-	<StructureSection load='3acx' size='340' side='right' caption='[[3acx]], [[Resolution\|resolution]] 1.31Å' scene=''>	+	<StructureSection load='3acx' size='340' side='right'caption='[[3acx]], [[Resolution\|resolution]] 1.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3acx]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ACX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3acx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ACX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=673:N-(1-METHYLETHYL)-3-[(3-PROP-2-EN-1-YLBIPHENYL-4-YL)OXY]PROPAN-1-AMINE'>673</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=673:N-(1-METHYLETHYL)-3-[(3-PROP-2-EN-1-YLBIPHENYL-4-YL)OXY]PROPAN-1-AMINE'>673</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zco\|2zco]], [[2zcp\|2zcp]], [[2zcq\|2zcq]], [[2zcr\|2zcr]], [[2zcs\|2zcs]], [[2zy1\|2zy1]], [[3acw\|3acw]], [[3acy\|3acy]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zco\|2zco]], [[2zcp\|2zcp]], [[2zcq\|2zcq]], [[2zcr\|2zcr]], [[2zcs\|2zcs]], [[2zy1\|2zy1]], [[3acw\|3acw]], [[3acy\|3acy]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CrtM ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CrtM ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3acx OCA], [~~http~~://pdbe.org/3acx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3acx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3acx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3acx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3acx OCA], [https://pdbe.org/3acx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3acx RCSB], [https://www.ebi.ac.uk/pdbsum/3acx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3acx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 3acx" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3acx" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Squalene synthase\|Squalene synthase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Jeng, W Y]]		[[Category: Jeng, W Y]]
	[[Category: Liu, C I]]		[[Category: Liu, C I]]

OCA at 07:49, 5 August 2016

2016-08-05T07:49:24Z

←Older revision		Revision as of 07:49, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673==		==Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673==
	<StructureSection load='3acx' size='340' side='right' caption='[[3acx]], [[Resolution\|resolution]] 1.31Å' scene=''>		<StructureSection load='3acx' size='340' side='right' caption='[[3acx]], [[Resolution\|resolution]] 1.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3acx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Staphylococcus_aureus Staphylococcus~~ aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ACX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3acx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ACX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=673:N-(1-METHYLETHYL)-3-[(3-PROP-2-EN-1-YLBIPHENYL-4-YL)OXY]PROPAN-1-AMINE'>673</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=673:N-(1-METHYLETHYL)-3-[(3-PROP-2-EN-1-YLBIPHENYL-4-YL)OXY]PROPAN-1-AMINE'>673</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zco\|2zco]], [[2zcp\|2zcp]], [[2zcq\|2zcq]], [[2zcr\|2zcr]], [[2zcs\|2zcs]], [[2zy1\|2zy1]], [[3acw\|3acw]], [[3acy\|3acy]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zco\|2zco]], [[2zcp\|2zcp]], [[2zcq\|2zcq]], [[2zcr\|2zcr]], [[2zcs\|2zcs]], [[2zy1\|2zy1]], [[3acw\|3acw]], [[3acy\|3acy]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CrtM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 ~~Staphylococcus~~ aureus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CrtM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3acx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3acx RCSB], [http://www.ebi.ac.uk/pdbsum/3acx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3acx OCA], [http://pdbe.org/3acx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3acx RCSB], [http://www.ebi.ac.uk/pdbsum/3acx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3acx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3acx" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Staphylococcus aureus]]
	[[Category: Jeng, W Y]]		[[Category: Jeng, W Y]]
	[[Category: Liu, C I]]		[[Category: Liu, C I]]

OCA at 14:25, 18 December 2014

2014-12-18T14:25:21Z

←Older revision		Revision as of 14:25, 18 December 2014
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-	~~{{STRUCTURE_3acx\| PDB=3acx \| SCENE= }}~~	+	==Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673==
-	===Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673===	+	<StructureSection load='3acx' size='340' side='right' caption='[[3acx]], [[Resolution\|resolution]] 1.31Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21098670}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3acx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ACX FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=673:N-(1-METHYLETHYL)-3-[(3-PROP-2-EN-1-YLBIPHENYL-4-YL)OXY]PROPAN-1-AMINE'>673</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zco\|2zco]], [[2zcp\|2zcp]], [[2zcq\|2zcq]], [[2zcr\|2zcr]], [[2zcs\|2zcs]], [[2zy1\|2zy1]], [[3acw\|3acw]], [[3acy\|3acy]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CrtM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3acx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3acx RCSB], [http://www.ebi.ac.uk/pdbsum/3acx PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	"Head-to-head" terpene synthases catalyze the first committed steps in sterol and carotenoid biosynthesis: the condensation of two isoprenoid diphosphates to form cyclopropylcarbinyl diphosphates, followed by ring opening. Here, we report the structures of Staphylococcus aureus dehydrosqualene synthase (CrtM) complexed with its reaction intermediate, presqualene diphosphate (PSPP), the dehydrosqualene (DHS) product, as well as a series of inhibitors. The results indicate that, on initial diphosphate loss, the primary carbocation so formed bends down into the interior of the protein to react with C2,3 double bond in the prenyl acceptor to form PSPP, with the lower two-thirds of both PSPP chains occupying essentially the same positions as found in the two farnesyl chains in the substrates. The second-half reaction is then initiated by the PSPP diphosphate returning back to the Mg(2+) cluster for ionization, with the resultant DHS so formed being trapped in a surface pocket. This mechanism is supported by the observation that cationic inhibitors (of interest as antiinfectives) bind with their positive charge located in the same region as the cyclopropyl carbinyl group; that S-thiolo-diphosphates only inhibit when in the allylic site; activity results on 11 mutants show that both DXXXD conserved domains are essential for PSPP ionization; and the observation that head-to-tail isoprenoid synthases as well as terpene cyclases have ionization and alkene-donor sites which spatially overlap those found in CrtM.

-	~~==About this Structure==~~	+	Mechanism of action and inhibition of dehydrosqualene synthase.,Lin FY, Liu CI, Liu YL, Zhang Y, Wang K, Jeng WY, Ko TP, Cao R, Wang AH, Oldfield E Proc Natl Acad Sci U S A. 2010 Nov 23. PMID:21098670<ref>PMID:21098670</ref>
-	~~[[3acx]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Staphylococcus_aureus Staphylococcus aureus]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3ACX OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:021098670</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
-	[[Category: Jeng, W Y.]]	+	[[Category: Jeng, W Y]]
-	[[Category: Liu, C I.]]	+	[[Category: Liu, C I]]
-	[[Category: Oldfield, E.]]	+	[[Category: Oldfield, E]]
-	[[Category: Wang, A H.J.]]	+	[[Category: Wang, A H.J]]
	[[Category: Carotenoid biosynthesis]]		[[Category: Carotenoid biosynthesis]]
	[[Category: Crtm]]		[[Category: Crtm]]

OCA at 08:43, 30 October 2013

2013-10-30T08:43:23Z

←Older revision		Revision as of 08:43, 30 October 2013
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-	[[Image:3acx.png\|left\|200px]]
-
	{{STRUCTURE_3acx\| PDB=3acx \| SCENE= }}		{{STRUCTURE_3acx\| PDB=3acx \| SCENE= }}
-
	===Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673===		===Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673===
-		+	{{ABSTRACT_PUBMED_21098670}}
-	{{~~ABSTRACT_PUBMED_18276850~~}}	+

	==About this Structure==		==About this Structure==
Line 11:		Line 7:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~018276850~~</ref><~~ref~~ group="xtra"~~>PMID:019456099<~~/~~ref~~><references ~~group="xtra"~~/>	+	<ref group="xtra">PMID:021098670</ref><references group="xtra"/><references/>
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
	[[Category: Jeng, W Y.]]		[[Category: Jeng, W Y.]]

OCA at 13:44, 6 February 2013

2013-02-06T13:44:48Z

←Older revision		Revision as of 13:44, 6 February 2013
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	[[Image:3acx.png\|left\|200px]]		[[Image:3acx.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3acx\| PDB=3acx \| SCENE= }}		{{STRUCTURE_3acx\| PDB=3acx \| SCENE= }}

	===Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673===		===Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18276850}}, adds the Publication Abstract to the page
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	{{ABSTRACT_PUBMED_18276850}}		{{ABSTRACT_PUBMED_18276850}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18276850~~</ref><ref group="xtra">PMID:~~19456099~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018276850</ref><ref group="xtra">PMID:019456099</ref><references group="xtra"/>
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
	[[Category: Jeng, W Y.]]		[[Category: Jeng, W Y.]]

OCA: Protected "3acx" [edit=sysop:move=sysop]

2011-03-15T00:44:23Z

Protected "3acx" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:44, 15 March 2011

OCA at 00:44, 15 March 2011

2011-03-15T00:44:21Z

←Older revision		Revision as of 00:44, 15 March 2011
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-	~~{{Seed}}~~	+	[[Image:3acx.png\|left\|200px]]
-	[[Image:3acx.~~jpg~~\|left\|200px]]	+

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	===Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673===		===Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_18276850}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18276850 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18276850}}

	==About this Structure==		==About this Structure==
-	~~3ACX~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACX OCA].	+	[[3acx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACX OCA].

	==Reference==		==Reference==
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	[[Category: Transferase]]		[[Category: Transferase]]
	[[Category: Transferase-transferase inhibitor complex]]		[[Category: Transferase-transferase inhibitor complex]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 14:12:14 2010''

OCA at 11:00, 24 November 2010

2010-11-24T11:00:44Z

←Older revision		Revision as of 11:00, 24 November 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3acx.jpg\|left\|200px]]

-	The ~~entry 3acx~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3acx", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3acx\| PDB=3acx \| SCENE= }}

-	~~Authors: Liu,~~ C~~.I., Jeng, W.Y., Wang, A.H.J., Oldfield, E.~~	+	===Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673===

-	Description: Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu Feb 25 12~~:53:51 2010''	+	==About this Structure==
		+	3ACX is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ACX OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:18276850</ref><ref group="xtra">PMID:19456099</ref><references group="xtra"/>
		+	[[Category: Staphylococcus aureus]]
		+	[[Category: Jeng, W Y.]]
		+	[[Category: Liu, C I.]]
		+	[[Category: Oldfield, E.]]
		+	[[Category: Wang, A H.J.]]
		+	[[Category: Carotenoid biosynthesis]]
		+	[[Category: Crtm]]
		+	[[Category: Head-to-head condensation]]
		+	[[Category: Inhibitor]]
		+	[[Category: Staphyloxanthin biosynthesis]]
		+	[[Category: Transferase]]
		+	[[Category: Transferase-transferase inhibitor complex]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 14:12:14 2010''

OCA at 10:53, 25 February 2010

2010-02-25T10:53:52Z

←Older revision		Revision as of 10:53, 25 February 2010
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3acx is ON HOLD	+	The entry 3acx is ON HOLD until Paper Publication

	Authors: Liu, C.I., Jeng, W.Y., Wang, A.H.J., Oldfield, E.		Authors: Liu, C.I., Jeng, W.Y., Wang, A.H.J., Oldfield, E.
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	Description: Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673		Description: Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with BPH-673

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jan 27 19~~:11:21 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 12:53:51 2010''