3arx - Revision history

OCA at 15:53, 4 October 2023

2023-10-04T15:53:31Z

←Older revision		Revision as of 15:53, 4 October 2023
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	<StructureSection load='3arx' size='340' side='right'caption='[[3arx]], [[Resolution\|resolution]] 1.16Å' scene=''>		<StructureSection load='3arx' size='340' side='right'caption='[[3arx]], [[Resolution\|resolution]] 1.16Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3arx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"achromobacter_harveyi"_johnson_and_shunk_1936 "achromobacter~~ harveyi~~" johnson and shunk 1936~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ARX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3arx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ARX FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=POY:3~~-~~METHYL-1-(5-OXOHEXYL)-7-PROPYL-3~~,~~7-DIHYDRO-1H-PURINE-2,6-DIONE'>POY</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.16Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; max-height: 3em;'>[[3aro\|3aro]], [[3arp\|3arp]], [[3arq\|3arq]], [[3arr\|3arr]], [[3ars\|3ars]], [[3art\|3art]], [[3aru\|3aru]], [[3arv\|3arv]], [[3arw\|3arw]], [[3ary\|3ary]], [[3arz\|3arz]], [[3as0\|3as0]], [[3as1\|3as1]], [[3as2\|3as2]], [[3as3\|3as3]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=POY:3-METHYL-1-(5-OXOHEXYL)-7-PROPYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE'>POY</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>CHIA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~669~~ "~~Achromobacter harveyi~~" ~~Johnson and Shunk 1936])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [https://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=3.2.~~1~~.14~~ 3.2~~.1.14]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3arx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3arx OCA], [https://pdbe.org/3arx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3arx RCSB], [https://www.ebi.ac.uk/pdbsum/3arx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3arx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3arx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3arx OCA], [https://pdbe.org/3arx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3arx RCSB], [https://www.ebi.ac.uk/pdbsum/3arx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3arx ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9AMP1_VIBHA Q9AMP1_VIBHA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Achromobacter harveyi johnson and shunk 1936]]
-	[[Category: Chitinase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Pantoom, S]]	+	[[Category: Vibrio harveyi]]
-	[[Category: Prinz, H]]	+	[[Category: Pantoom S]]
-	[[Category: Suginta, W]]	+	[[Category: Prinz H]]
-	[[Category: Vetter~~, I R]]~~	+	[[Category: Suginta W]]
-	~~[[Category: Glycosidase]]~~	+	[[Category: Vetter IR]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hydrolase-hydrolase inhibitor complex]]~~	+
-	~~[[Category: Inhibitor complex]]~~	+
-	~~[[Category: Tim barrel~~]]	+

OCA at 15:02, 29 December 2021

2021-12-29T15:02:31Z

←Older revision		Revision as of 15:02, 29 December 2021
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	==Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline==		==Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline==
-	<StructureSection load='3arx' size='340' side='right' caption='[[3arx]], [[Resolution\|resolution]] 1.16Å' scene=''>	+	<StructureSection load='3arx' size='340' side='right'caption='[[3arx]], [[Resolution\|resolution]] 1.16Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3arx]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"achromobacter_harveyi"_johnson_and_shunk_1936 "achromobacter harveyi" johnson and shunk 1936]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ARX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3arx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"achromobacter_harveyi"_johnson_and_shunk_1936 "achromobacter harveyi" johnson and shunk 1936]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ARX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=POY:3-METHYL-1-(5-OXOHEXYL)-7-PROPYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE'>POY</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=POY:3-METHYL-1-(5-OXOHEXYL)-7-PROPYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE'>POY</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aro\|3aro]], [[3arp\|3arp]], [[3arq\|3arq]], [[3arr\|3arr]], [[3ars\|3ars]], [[3art\|3art]], [[3aru\|3aru]], [[3arv\|3arv]], [[3arw\|3arw]], [[3ary\|3ary]], [[3arz\|3arz]], [[3as0\|3as0]], [[3as1\|3as1]], [[3as2\|3as2]], [[3as3\|3as3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3aro\|3aro]], [[3arp\|3arp]], [[3arq\|3arq]], [[3arr\|3arr]], [[3ars\|3ars]], [[3art\|3art]], [[3aru\|3aru]], [[3arv\|3arv]], [[3arw\|3arw]], [[3ary\|3ary]], [[3arz\|3arz]], [[3as0\|3as0]], [[3as1\|3as1]], [[3as2\|3as2]], [[3as3\|3as3]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CHIA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=669 "Achromobacter harveyi" Johnson and Shunk 1936])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CHIA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=669 "Achromobacter harveyi" Johnson and Shunk 1936])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3arx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3arx OCA], [~~http~~://pdbe.org/3arx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3arx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3arx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3arx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3arx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3arx OCA], [https://pdbe.org/3arx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3arx RCSB], [https://www.ebi.ac.uk/pdbsum/3arx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3arx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
-	*[[Chitinase\|Chitinase]]	+	*[[Chitinase 3D structures\|Chitinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 28:
	[[Category: Achromobacter harveyi johnson and shunk 1936]]		[[Category: Achromobacter harveyi johnson and shunk 1936]]
	[[Category: Chitinase]]		[[Category: Chitinase]]
		+	[[Category: Large Structures]]
	[[Category: Pantoom, S]]		[[Category: Pantoom, S]]
	[[Category: Prinz, H]]		[[Category: Prinz, H]]

OCA at 18:22, 5 August 2016

2016-08-05T18:22:20Z

←Older revision		Revision as of 18:22, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline==		==Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline==
	<StructureSection load='3arx' size='340' side='right' caption='[[3arx]], [[Resolution\|resolution]] 1.16Å' scene=''>		<StructureSection load='3arx' size='340' side='right' caption='[[3arx]], [[Resolution\|resolution]] 1.16Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CHIA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=669 "Achromobacter harveyi" Johnson and Shunk 1936])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CHIA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=669 "Achromobacter harveyi" Johnson and Shunk 1936])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3arx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3arx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3arx RCSB], [http://www.ebi.ac.uk/pdbsum/3arx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3arx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3arx OCA], [http://pdbe.org/3arx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3arx RCSB], [http://www.ebi.ac.uk/pdbsum/3arx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3arx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3arx" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 16:22, 21 December 2014

2014-12-21T16:22:10Z

←Older revision		Revision as of 16:22, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3arx\| PDB=3arx \| SCENE= }}~~	+	==Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline==
-	===Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline===	+	<StructureSection load='3arx' size='340' side='right' caption='[[3arx]], [[Resolution\|resolution]] 1.16Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21531720}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3arx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_harveyi"_johnson_and_shunk_1936 "achromobacter harveyi" johnson and shunk 1936]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ARX FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=POY:3-METHYL-1-(5-OXOHEXYL)-7-PROPYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE'>POY</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aro\|3aro]], [[3arp\|3arp]], [[3arq\|3arq]], [[3arr\|3arr]], [[3ars\|3ars]], [[3art\|3art]], [[3aru\|3aru]], [[3arv\|3arv]], [[3arw\|3arw]], [[3ary\|3ary]], [[3arz\|3arz]], [[3as0\|3as0]], [[3as1\|3as1]], [[3as2\|3as2]], [[3as3\|3as3]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CHIA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=669 "Achromobacter harveyi" Johnson and Shunk 1936])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3arx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3arx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3arx RCSB], [http://www.ebi.ac.uk/pdbsum/3arx PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Six novel inhibitors of Vibrio harveyi chitinase A (VhChiA), a family-18 chitinase homolog, were identified by in vitro screening of a library of pharmacologically active compounds. Unlike the previously identified inhibitors that mimicked the reaction intermediates, crystallographic evidence from 14 VhChiA-inhibitor complexes showed that all of the inhibitor molecules occupied the outer part of the substrate-binding cleft at two hydrophobic areas. The interactions at the aglycone location are well defined and tightly associated with Trp-397 and Trp-275, whereas the interactions at the glycone location are patchy, indicating lower affinity and a loose interaction with two consensus residues, Trp-168 and Val-205. When Trp-275 was substituted with glycine (W275G), the binding affinity toward all of the inhibitors dramatically decreased, and in most structures two inhibitor molecules were found to stack against Trp-397 at the aglycone site. Such results indicate that hydrophobic interactions are important for binding of the newly identified inhibitors by the chitinase. X-ray data and isothermal microcalorimetry showed that the inhibitors occupied the active site of VhChiA in three different binding modes, including single-site binding, independent two-site binding, and sequential two-site binding. The inhibitory effect of dequalinium in the low nanomolar range makes this compound an extremely attractive lead compound for plausible development of therapeutics against human diseases involving chitinase-mediated pathologies.

-	~~==About this Structure==~~	+	Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms.,Pantoom S, Vetter IR, Prinz H, Suginta W J Biol Chem. 2011 Jul 8;286(27):24312-23. Epub 2011 Apr 29. PMID:21531720<ref>PMID:21531720</ref>
-	~~[[3arx]] is a 1 chain structure with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki/"achromobacter_harveyi"_johnson_and_shunk_1936 "achromobacter harveyi" johnson and shunk 1936]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3ARX OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Chitinase\|Chitinase]]		*[[Chitinase\|Chitinase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:021531720</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Achromobacter harveyi johnson and shunk 1936]]		[[Category: Achromobacter harveyi johnson and shunk 1936]]
	[[Category: Chitinase]]		[[Category: Chitinase]]
-	[[Category: Pantoom, S.]]	+	[[Category: Pantoom, S]]
-	[[Category: Prinz, H.]]	+	[[Category: Prinz, H]]
-	[[Category: Suginta, W.]]	+	[[Category: Suginta, W]]
-	[[Category: Vetter, I R.]]	+	[[Category: Vetter, I R]]
	[[Category: Glycosidase]]		[[Category: Glycosidase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 06:04, 29 January 2014

2014-01-29T06:04:15Z

←Older revision		Revision as of 06:04, 29 January 2014
Line 1:		Line 1:
-	[[Image:3arx.png\|left\|200px]]
-
	{{STRUCTURE_3arx\| PDB=3arx \| SCENE= }}		{{STRUCTURE_3arx\| PDB=3arx \| SCENE= }}
-
	===Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline===		===Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline===
-		+	{{ABSTRACT_PUBMED_21531720}}
-	{{~~ABSTRACT_PUBMED_18467126~~}}	+

	==About this Structure==		==About this Structure==
-	[[3arx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Vibrio_harveyi Vibrio~~ harveyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA].	+	[[3arx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_harveyi"_johnson_and_shunk_1936 "achromobacter harveyi" johnson and shunk 1936]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA].

	==See Also==		==See Also==
Line 14:		Line 10:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~018467126~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021531720</ref><references group="xtra"/><references/>
		+	[[Category: Achromobacter harveyi johnson and shunk 1936]]
	[[Category: Chitinase]]		[[Category: Chitinase]]
-	[[Category: Vibrio harveyi]]
	[[Category: Pantoom, S.]]		[[Category: Pantoom, S.]]
	[[Category: Prinz, H.]]		[[Category: Prinz, H.]]

OCA at 12:49, 20 October 2012

2012-10-20T12:49:35Z

←Older revision		Revision as of 12:49, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3arx]] is a 1 chain structure ~~of [[Chitinase]]~~ with sequence from [http://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA].	+	[[3arx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA].

	==See Also==		==See Also==

OCA at 10:01, 26 July 2012

2012-07-26T10:01:08Z

←Older revision		Revision as of 10:01, 26 July 2012
Line 1:		Line 1:
-	[[Image:3arx.~~jpg~~\|left\|200px]]	+	[[Image:3arx.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3arx", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3arx\| PDB=3arx \| SCENE= }}		{{STRUCTURE_3arx\| PDB=3arx \| SCENE= }}

	===Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline===		===Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18467126}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18467126 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18467126}}		{{ABSTRACT_PUBMED_18467126}}

	==About this Structure==		==About this Structure==
-	[[3arx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA].	+	[[3arx]] is a 1 chain structure of [[Chitinase]] with sequence from [http://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA].
		+
		+	==See Also==
		+	*[[Chitinase\|Chitinase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18467126~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018467126</ref><references group="xtra"/>
	[[Category: Chitinase]]		[[Category: Chitinase]]
	[[Category: Vibrio harveyi]]		[[Category: Vibrio harveyi]]
Line 29:		Line 21:
	[[Category: Suginta, W.]]		[[Category: Suginta, W.]]
	[[Category: Vetter, I R.]]		[[Category: Vetter, I R.]]
		+	[[Category: Glycosidase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Inhibitor complex]]
		+	[[Category: Tim barrel]]

OCA at 10:47, 21 April 2011

2011-04-21T10:47:24Z

←Older revision		Revision as of 10:47, 21 April 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3arx.jpg\|left\|200px]]

-	The ~~entry 3arx~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3arx", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3arx\| PDB=3arx \| SCENE= }}

-	~~Authors: Pantoom, S., Vetter, I.R., Prinz, H., Suginta, W.~~	+	===Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline===

-	~~Description~~: ~~Crystal~~ Structure ~~Analysis of Chitinase A~~ from Vibrio harveyi ~~with novel inhibitors~~ -~~complex structure with Propentofylline~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_18467126}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18467126 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18467126}}
		+
		+	==About this Structure==
		+	[[3arx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARX OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:18467126</ref><references group="xtra"/>
		+	[[Category: Chitinase]]
		+	[[Category: Vibrio harveyi]]
		+	[[Category: Pantoom, S.]]
		+	[[Category: Prinz, H.]]
		+	[[Category: Suginta, W.]]
		+	[[Category: Vetter, I R.]]

OCA at 04:42, 12 January 2011

2011-01-12T04:42:46Z

←Older revision		Revision as of 04:42, 12 January 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3arx is ON HOLD	+	The entry 3arx is ON HOLD until Paper Publication

	Authors: Pantoom, S., Vetter, I.R., Prinz, H., Suginta, W.		Authors: Pantoom, S., Vetter, I.R., Prinz, H., Suginta, W.

	Description: Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors -complex structure with Propentofylline		Description: Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors -complex structure with Propentofylline

OCA: Protected "3arx" [edit=sysop:move=sysop]

2011-01-05T15:48:43Z

Protected "3arx" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:48, 5 January 2011