3awx - Revision history

OCA at 15:59, 4 October 2023

2023-10-04T15:59:06Z

←Older revision		Revision as of 15:59, 4 October 2023
Line 3:		Line 3:
	<StructureSection load='3awx' size='340' side='right'caption='[[3awx]], [[Resolution\|resolution]] 1.25Å' scene=''>		<StructureSection load='3awx' size='340' side='right'caption='[[3awx]], [[Resolution\|resolution]] 1.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3awx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"actinomyces_castaneoglobisporus"_yen "actinomyces~~ castaneoglobisporus~~" yen~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AWX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3awx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_castaneoglobisporus Streptomyces castaneoglobisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AWX FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>~~, ~~<scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.25Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3aws\|3aws]], [[3awt\|3awt]], [[3awu\|3awu]], [[3awv\|3awv]], [[3aww\|3aww]], [[3awy\|3awy]], [[3awz\|3awz]], [[3ax0\|3ax0]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>TYRC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~79261~~ "~~Actinomyces castaneoglobisporus~~" ~~Yen]), ORF378 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 "Actinomyces castaneoglobisporus" Yen])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Tyrosinase Tyrosinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.18.1 1.14.18.1]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3awx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3awx OCA], [https://pdbe.org/3awx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3awx RCSB], [https://www.ebi.ac.uk/pdbsum/3awx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3awx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3awx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3awx OCA], [https://pdbe.org/3awx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3awx RCSB], [https://www.ebi.ac.uk/pdbsum/3awx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3awx ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q83WS2_9ACTN Q83WS2_9ACTN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Actinomyces castaneoglobisporus yen]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Tyrosinase~~]]	+	[[Category: Streptomyces castaneoglobisporus]]
-	[[Category: Matoba, Y]]	+	[[Category: Matoba Y]]
-	[[Category: Sugiyama, M]]	+	[[Category: Sugiyama M]]
-	~~[[Category: Binary complex]]~~	+
-	~~[[Category: Copper transfer]]~~	+
-	~~[[Category: Dioxygen]]~~	+
-	~~[[Category: Oxidoreductase-metal transport complex]]~~	+
-	~~[[Category: Type-3 copper~~]]	+

OCA at 15:07, 29 December 2021

2021-12-29T15:07:12Z

←Older revision		Revision as of 15:07, 29 December 2021
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	==Crystal structure of Streptomyces tyrosinase in a complex with caddie H82Q mutant soaked in a Cu(II)-containing solution for 80 hr==		==Crystal structure of Streptomyces tyrosinase in a complex with caddie H82Q mutant soaked in a Cu(II)-containing solution for 80 hr==
-	<StructureSection load='3awx' size='340' side='right' caption='[[3awx]], [[Resolution\|resolution]] 1.25Å' scene=''>	+	<StructureSection load='3awx' size='340' side='right'caption='[[3awx]], [[Resolution\|resolution]] 1.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3awx]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"actinomyces_castaneoglobisporus"_yen "actinomyces castaneoglobisporus" yen]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3AWX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3awx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"actinomyces_castaneoglobisporus"_yen "actinomyces castaneoglobisporus" yen]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AWX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aws\|3aws]], [[3awt\|3awt]], [[3awu\|3awu]], [[3awv\|3awv]], [[3aww\|3aww]], [[3awy\|3awy]], [[3awz\|3awz]], [[3ax0\|3ax0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3aws\|3aws]], [[3awt\|3awt]], [[3awu\|3awu]], [[3awv\|3awv]], [[3aww\|3aww]], [[3awy\|3awy]], [[3awz\|3awz]], [[3ax0\|3ax0]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TYRC ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 "Actinomyces castaneoglobisporus" Yen]), ORF378 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 "Actinomyces castaneoglobisporus" Yen])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TYRC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 "Actinomyces castaneoglobisporus" Yen]), ORF378 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 "Actinomyces castaneoglobisporus" Yen])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Tyrosinase Tyrosinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.18.1 1.14.18.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Tyrosinase Tyrosinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.18.1 1.14.18.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3awx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3awx OCA], [~~http~~://pdbe.org/3awx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3awx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3awx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3awx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3awx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3awx OCA], [https://pdbe.org/3awx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3awx RCSB], [https://www.ebi.ac.uk/pdbsum/3awx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3awx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[Tyrosinase\|Tyrosinase]]	+	*[[Tyrosinase 3D structures\|Tyrosinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 27:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Actinomyces castaneoglobisporus yen]]		[[Category: Actinomyces castaneoglobisporus yen]]
		+	[[Category: Large Structures]]
	[[Category: Tyrosinase]]		[[Category: Tyrosinase]]
	[[Category: Matoba, Y]]		[[Category: Matoba, Y]]

OCA at 07:38, 5 August 2016

2016-08-05T07:38:51Z

←Older revision		Revision as of 07:38, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of Streptomyces tyrosinase in a complex with caddie H82Q mutant soaked in a Cu(II)-containing solution for 80 hr==		==Crystal structure of Streptomyces tyrosinase in a complex with caddie H82Q mutant soaked in a Cu(II)-containing solution for 80 hr==
	<StructureSection load='3awx' size='340' side='right' caption='[[3awx]], [[Resolution\|resolution]] 1.25Å' scene=''>		<StructureSection load='3awx' size='340' side='right' caption='[[3awx]], [[Resolution\|resolution]] 1.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3awx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptomyces_castaneoglobisporus Streptomyces~~ castaneoglobisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AWX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3awx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinomyces_castaneoglobisporus"_yen "actinomyces castaneoglobisporus" yen]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AWX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aws\|3aws]], [[3awt\|3awt]], [[3awu\|3awu]], [[3awv\|3awv]], [[3aww\|3aww]], [[3awy\|3awy]], [[3awz\|3awz]], [[3ax0\|3ax0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aws\|3aws]], [[3awt\|3awt]], [[3awu\|3awu]], [[3awv\|3awv]], [[3aww\|3aww]], [[3awy\|3awy]], [[3awz\|3awz]], [[3ax0\|3ax0]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TYRC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 ~~Streptomyces~~ castaneoglobisporus]), ORF378 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 ~~Streptomyces~~ castaneoglobisporus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TYRC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 "Actinomyces castaneoglobisporus" Yen]), ORF378 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 "Actinomyces castaneoglobisporus" Yen])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Monophenol_monooxygenase Monophenol monooxygenase~~], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.18.1 1.14.18.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tyrosinase Tyrosinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.18.1 1.14.18.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3awx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3awx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3awx RCSB], [http://www.ebi.ac.uk/pdbsum/3awx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3awx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3awx OCA], [http://pdbe.org/3awx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3awx RCSB], [http://www.ebi.ac.uk/pdbsum/3awx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3awx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3awx" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Tyrosinase\|Tyrosinase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Monophenol monooxygenase~~]]	+	[[Category: Actinomyces castaneoglobisporus yen]]
-	[[Category: ~~Streptomyces castaneoglobisporus~~]]	+	[[Category: Tyrosinase]]
	[[Category: Matoba, Y]]		[[Category: Matoba, Y]]
	[[Category: Sugiyama, M]]		[[Category: Sugiyama, M]]
Line 30:		Line 35:
	[[Category: Oxidoreductase-metal transport complex]]		[[Category: Oxidoreductase-metal transport complex]]
	[[Category: Type-3 copper]]		[[Category: Type-3 copper]]
-	[[Category: Tyrosinase]]

OCA at 23:16, 3 January 2015

2015-01-03T23:16:40Z

←Older revision		Revision as of 23:16, 3 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3awx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_castaneoglobisporus Streptomyces castaneoglobisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AWX FirstGlance]. <br>		<table><tr><td colspan='2'>[[3awx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_castaneoglobisporus Streptomyces castaneoglobisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AWX FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aws\|3aws]], [[3awt\|3awt]], [[3awu\|3awu]], [[3awv\|3awv]], [[3aww\|3aww]], [[3awy\|3awy]], [[3awz\|3awz]], [[3ax0\|3ax0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aws\|3aws]], [[3awt\|3awt]], [[3awu\|3awu]], [[3awv\|3awv]], [[3aww\|3aww]], [[3awy\|3awy]], [[3awz\|3awz]], [[3ax0\|3ax0]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TYRC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 Streptomyces castaneoglobisporus]), ORF378 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 Streptomyces castaneoglobisporus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TYRC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 Streptomyces castaneoglobisporus]), ORF378 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 Streptomyces castaneoglobisporus])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Monophenol_monooxygenase Monophenol monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.18.1 1.14.18.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Monophenol_monooxygenase Monophenol monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.18.1 1.14.18.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3awx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3awx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3awx RCSB], [http://www.ebi.ac.uk/pdbsum/3awx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3awx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3awx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3awx RCSB], [http://www.ebi.ac.uk/pdbsum/3awx PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 15:		Line 15:
	A molecular mechanism for copper transportation to tyrosinase that is assisted by a metallochaperone, caddie protein.,Matoba Y, Bando N, Oda K, Noda M, Higashikawa F, Kumagai T, Sugiyama M J Biol Chem. 2011 Aug 26;286(34):30219-31. Epub 2011 Jul 5. PMID:21730070<ref>PMID:21730070</ref>		A molecular mechanism for copper transportation to tyrosinase that is assisted by a metallochaperone, caddie protein.,Matoba Y, Bando N, Oda K, Noda M, Higashikawa F, Kumagai T, Sugiyama M J Biol Chem. 2011 Aug 26;286(34):30219-31. Epub 2011 Jul 5. PMID:21730070<ref>PMID:21730070</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 23:		Line 23:
	[[Category: Monophenol monooxygenase]]		[[Category: Monophenol monooxygenase]]
	[[Category: Streptomyces castaneoglobisporus]]		[[Category: Streptomyces castaneoglobisporus]]
-	[[Category: Matoba, Y.]]	+	[[Category: Matoba, Y]]
-	[[Category: Sugiyama, M.]]	+	[[Category: Sugiyama, M]]
	[[Category: Binary complex]]		[[Category: Binary complex]]
	[[Category: Copper transfer]]		[[Category: Copper transfer]]

OCA at 11:04, 14 May 2014

2014-05-14T11:04:28Z

←Older revision		Revision as of 11:04, 14 May 2014
Line 1:		Line 1:
-	[[~~Image:~~3awx.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of Streptomyces tyrosinase in a complex with caddie H82Q mutant soaked in a Cu(II)-containing solution for 80 hr==
		+	<StructureSection load='3awx' size='340' side='right' caption='[[3awx]], [[Resolution\|resolution]] 1.25Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3awx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_castaneoglobisporus Streptomyces castaneoglobisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AWX FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3aws\|3aws]], [[3awt\|3awt]], [[3awu\|3awu]], [[3awv\|3awv]], [[3aww\|3aww]], [[3awy\|3awy]], [[3awz\|3awz]], [[3ax0\|3ax0]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TYRC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 Streptomyces castaneoglobisporus]), ORF378 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=79261 Streptomyces castaneoglobisporus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Monophenol_monooxygenase Monophenol monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.18.1 1.14.18.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3awx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3awx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3awx RCSB], [http://www.ebi.ac.uk/pdbsum/3awx PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Cu(II)-soaked crystal structure of tyrosinase that is present in a complex with a protein, designated "caddie," which we previously determined, possesses two copper ions at its catalytic center. We had identified two copper-binding sites in the caddie protein and speculated that copper bound to caddie may be transported to the tyrosinase catalytic center. In our present study, at a 1.16-1.58 A resolution, we determined the crystal structures of tyrosinase complexed with caddie prepared by altering the soaking time of the copper ion and the structures of tyrosinase complexed with different caddie mutants that display little or no capacity to activate tyrosinase. Based on these structures, we propose a molecular mechanism by which two copper ions are transported to the tyrosinase catalytic center with the assistance of caddie acting as a metallochaperone.

-	~~<!--~~	+	A molecular mechanism for copper transportation to tyrosinase that is assisted by a metallochaperone, caddie protein.,Matoba Y, Bando N, Oda K, Noda M, Higashikawa F, Kumagai T, Sugiyama M J Biol Chem. 2011 Aug 26;286(34):30219-31. Epub 2011 Jul 5. PMID:21730070<ref>PMID:21730070</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3awx"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_3awx\| PDB=3awx \| SCENE= }}~~	+

-	~~===Crystal structure~~ of ~~Streptomyces tyrosinase in a complex with caddie H82Q mutant soaked in a Cu(II)-containing solution for 80 hr===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21730070}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21730070 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21730070}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3awx]] is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Streptomyces_castaneoglobisporus Streptomyces castaneoglobisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWX OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021730070<~~/~~ref~~><~~ref group="xtra">PMID:016436386</ref><references group="xtra"~~/>	+
	[[Category: Monophenol monooxygenase]]		[[Category: Monophenol monooxygenase]]
	[[Category: Streptomyces castaneoglobisporus]]		[[Category: Streptomyces castaneoglobisporus]]

OCA at 05:49, 31 August 2011

2011-08-31T05:49:37Z

←Older revision		Revision as of 05:49, 31 August 2011
Line 1:		Line 1:
-	[[Image:3awx.~~jpg~~\|left\|200px]]	+	[[Image:3awx.png\|left\|200px]]

	<!--		<!--
Line 13:		Line 13:

	<!--		<!--
-	The line below this paragraph, {{~~ABSTRACT_PUBMED_16436386~~}}, adds the Publication Abstract to the page	+	The line below this paragraph, {{ABSTRACT_PUBMED_21730070}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where ~~16436386~~ is the PubMed ID number.	+	(as it appears on PubMed at http://www.pubmed.gov), where 21730070 is the PubMed ID number.
	-->		-->
-	{{~~ABSTRACT_PUBMED_16436386~~}}	+	{{ABSTRACT_PUBMED_21730070}}

	==About this Structure==		==About this Structure==
Line 22:		Line 22:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:016436386</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021730070</ref><ref group="xtra">PMID:016436386</ref><references group="xtra"/>
	[[Category: Monophenol monooxygenase]]		[[Category: Monophenol monooxygenase]]
	[[Category: Streptomyces castaneoglobisporus]]		[[Category: Streptomyces castaneoglobisporus]]

OCA at 06:15, 29 June 2011

2011-06-29T06:15:58Z

←Older revision		Revision as of 06:15, 29 June 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3awx.jpg\|left\|200px]]

-	The ~~entry 3awx~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3awx", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3awx\| PDB=3awx \| SCENE= }}

-	~~Authors: Matoba, Y., Sugiyama, M.~~	+	===Crystal structure of Streptomyces tyrosinase in a complex with caddie H82Q mutant soaked in a Cu(II)-containing solution for 80 hr===

-	~~Description~~: ~~Crystal~~ structure of Streptomyces ~~tyrosinase in a~~ complex ~~with caddie H82Q mutant soaked in a Cu(II)~~-~~containing solution for 80 hr~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_16436386}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 16436386 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_16436386}}
		+
		+	==About this Structure==
		+	[[3awx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_castaneoglobisporus Streptomyces castaneoglobisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AWX OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:016436386</ref><references group="xtra"/>
		+	[[Category: Monophenol monooxygenase]]
		+	[[Category: Streptomyces castaneoglobisporus]]
		+	[[Category: Matoba, Y.]]
		+	[[Category: Sugiyama, M.]]
		+	[[Category: Binary complex]]
		+	[[Category: Copper transfer]]
		+	[[Category: Dioxygen]]
		+	[[Category: Oxidoreductase-metal transport complex]]
		+	[[Category: Type-3 copper]]
		+	[[Category: Tyrosinase]]

OCA at 04:49, 13 April 2011

2011-04-13T04:49:10Z

←Older revision		Revision as of 04:49, 13 April 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3awx is ON HOLD	+	The entry 3awx is ON HOLD until Paper Publication

	Authors: Matoba, Y., Sugiyama, M.		Authors: Matoba, Y., Sugiyama, M.

-	Description: Crystal structure ~~analysis~~ of Streptomyces tyrosinase in a complex with caddie	+	Description: Crystal structure of Streptomyces tyrosinase in a complex with caddie H82Q mutant soaked in a Cu(II)-containing solution for 80 hr

OCA: Protected "3awx" [edit=sysop:move=sysop]

2011-04-06T08:29:46Z

Protected "3awx" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:29, 6 April 2011

OCA: New page: '''Unreleased structure''' The entry 3awx is ON HOLD Authors: Matoba, Y., Sugiyama, M. Description: Crystal structure analysis of Streptomyces tyrosinase in a complex with caddie

2011-04-06T08:29:44Z

New page: '''Unreleased structure''' The entry 3awx is ON HOLD Authors: Matoba, Y., Sugiyama, M. Description: Crystal structure analysis of Streptomyces tyrosinase in a complex with caddie

New page

'''Unreleased structure'''

The entry 3awx is ON HOLD

Authors: Matoba, Y., Sugiyama, M.

Description: Crystal structure analysis of Streptomyces tyrosinase in a complex with caddie