3brz - Revision history

OCA at 09:30, 21 February 2024

2024-02-21T09:30:55Z

←Older revision		Revision as of 09:30, 21 February 2024
Line 3:		Line 3:
	<StructureSection load='3brz' size='340' side='right'caption='[[3brz]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3brz' size='340' side='right'caption='[[3brz]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3brz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Pseudomonas_putida~~ Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BRZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3brz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida_F1 Pseudomonas putida F1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BRZ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[3bry\|3bry]], [[3bs0\|3bs0]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">todX ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3brz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brz OCA], [https://pdbe.org/3brz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3brz RCSB], [https://www.ebi.ac.uk/pdbsum/3brz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3brz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3brz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brz OCA], [https://pdbe.org/3brz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3brz RCSB], [https://www.ebi.ac.uk/pdbsum/3brz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3brz ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A5W4F4_PSEP1 A5W4F4_PSEP1]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3brz ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3brz ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Bacterial biodegradation of hydrocarbons, an important process for environmental remediation, requires the passage of hydrophobic substrates across the cell membrane. Here, we report crystal structures of two outer membrane proteins, Pseudomonas putida TodX and Ralstonia pickettii TbuX, which have been implicated in hydrocarbon transport and are part of a subfamily of the FadL fatty acid transporter family. The structures of TodX and TbuX show significant differences with those previously determined for Escherichia coli FadL, which may provide an explanation for the substrate-specific transport of TodX and TbuX observed with in vivo transport assays. The TodX and TbuX structures revealed 14-stranded beta-barrels with an N-terminal hatch domain blocking the barrel interior. A hydrophobic channel with bound detergent molecules extends from the extracellular surface and is contiguous with a passageway through the hatch domain, lined by both hydrophobic and polar or charged residues. The TodX and TbuX structures support a mechanism for transport of hydrophobic substrates from the extracellular environment to the periplasm via a channel through the hatch domain.
-
-	Outer-membrane transport of aromatic hydrocarbons as a first step in biodegradation.,Hearn EM, Patel DR, van den Berg B Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8601-6. Epub 2008 Jun 16. PMID:18559855<ref>PMID:18559855</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3brz" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Pseudomonas putida]]	+	[[Category: Pseudomonas putida F1]]
-	~~[[Category: Berg, B van den~~]]	+	[[Category: Hearn EM]]
-	[[Category: Hearn~~, E M~~]]	+	[[Category: Patel DR]]
-	[[Category: Patel~~, D R~~]]	+	[[Category: Van den Berg B]]
-	[[Category: ~~Beta barrel]]~~	+
-	~~[[Category: Outer membrane protein]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 08:23, 19 January 2022

2022-01-19T08:23:37Z

←Older revision		Revision as of 08:23, 19 January 2022
Line 1:		Line 1:

	==Crystal structure of the Pseudomonas putida toluene transporter TodX==		==Crystal structure of the Pseudomonas putida toluene transporter TodX==
-	<StructureSection load='3brz' size='340' side='right' caption='[[3brz]], [[Resolution\|resolution]] 3.20Å' scene=''>	+	<StructureSection load='3brz' size='340' side='right'caption='[[3brz]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3brz]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3BRZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3brz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BRZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bry\|3bry]], [[3bs0\|3bs0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3bry\|3bry]], [[3bs0\|3bs0]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">todX ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">todX ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3brz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brz OCA], [~~http~~://pdbe.org/3brz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3brz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3brz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3brz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3brz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brz OCA], [https://pdbe.org/3brz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3brz RCSB], [https://www.ebi.ac.uk/pdbsum/3brz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3brz ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pseudomonas putida]]		[[Category: Pseudomonas putida]]
	[[Category: Berg, B van den]]		[[Category: Berg, B van den]]

OCA at 08:12, 31 October 2018

2018-10-31T08:12:15Z

←Older revision		Revision as of 08:12, 31 October 2018
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/3brz_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/3brz_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 13:53, 11 August 2016

2016-08-11T13:53:54Z

←Older revision		Revision as of 13:53, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the Pseudomonas putida toluene transporter TodX==		==Crystal structure of the Pseudomonas putida toluene transporter TodX==
	<StructureSection load='3brz' size='340' side='right' caption='[[3brz]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3brz' size='340' side='right' caption='[[3brz]], [[Resolution\|resolution]] 3.20Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bry\|3bry]], [[3bs0\|3bs0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bry\|3bry]], [[3bs0\|3bs0]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">todX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">todX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3brz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3brz RCSB], [http://www.ebi.ac.uk/pdbsum/3brz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3brz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brz OCA], [http://pdbe.org/3brz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3brz RCSB], [http://www.ebi.ac.uk/pdbsum/3brz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3brz ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3brz ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3brz" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:42, 20 January 2015

2015-01-20T11:42:09Z

←Older revision		Revision as of 11:42, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3brz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BRZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[3brz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BRZ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bry\|3bry]], [[3bs0\|3bs0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bry\|3bry]], [[3bs0\|3bs0]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">todX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">todX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3brz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3brz RCSB], [http://www.ebi.ac.uk/pdbsum/3brz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3brz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3brz RCSB], [http://www.ebi.ac.uk/pdbsum/3brz PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Pseudomonas putida]]		[[Category: Pseudomonas putida]]
-	[[Category: Berg, B van den.]]	+	[[Category: Berg, B van den]]
-	[[Category: Hearn, E M.]]	+	[[Category: Hearn, E M]]
-	[[Category: Patel, D R.]]	+	[[Category: Patel, D R]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Outer membrane protein]]		[[Category: Outer membrane protein]]
	[[Category: Transport protein]]		[[Category: Transport protein]]

OCA at 21:27, 2 October 2014

2014-10-02T21:27:50Z

←Older revision		Revision as of 21:27, 2 October 2014
Line 1:		Line 1:
-	[[~~Image:~~3brz.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of the Pseudomonas putida toluene transporter TodX==
		+	<StructureSection load='3brz' size='340' side='right' caption='[[3brz]], [[Resolution\|resolution]] 3.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3brz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BRZ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bry\|3bry]], [[3bs0\|3bs0]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">todX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3brz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3brz RCSB], [http://www.ebi.ac.uk/pdbsum/3brz PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/3brz_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacterial biodegradation of hydrocarbons, an important process for environmental remediation, requires the passage of hydrophobic substrates across the cell membrane. Here, we report crystal structures of two outer membrane proteins, Pseudomonas putida TodX and Ralstonia pickettii TbuX, which have been implicated in hydrocarbon transport and are part of a subfamily of the FadL fatty acid transporter family. The structures of TodX and TbuX show significant differences with those previously determined for Escherichia coli FadL, which may provide an explanation for the substrate-specific transport of TodX and TbuX observed with in vivo transport assays. The TodX and TbuX structures revealed 14-stranded beta-barrels with an N-terminal hatch domain blocking the barrel interior. A hydrophobic channel with bound detergent molecules extends from the extracellular surface and is contiguous with a passageway through the hatch domain, lined by both hydrophobic and polar or charged residues. The TodX and TbuX structures support a mechanism for transport of hydrophobic substrates from the extracellular environment to the periplasm via a channel through the hatch domain.

-	~~{{STRUCTURE_3brz\| PDB=3brz \| SCENE= }}~~	+	Outer-membrane transport of aromatic hydrocarbons as a first step in biodegradation.,Hearn EM, Patel DR, van den Berg B Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8601-6. Epub 2008 Jun 16. PMID:18559855<ref>PMID:18559855</ref>

-	~~===Crystal structure~~ of the ~~Pseudomonas putida toluene transporter TodX===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18559855}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3brz]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pseudomonas_putida Pseudomonas putida]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018559855<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Pseudomonas putida]]		[[Category: Pseudomonas putida]]
	[[Category: Berg, B van den.]]		[[Category: Berg, B van den.]]

OCA: Protected "3brz" [edit=sysop:move=sysop]

2013-01-07T23:10:16Z

Protected "3brz" [edit=sysop:move=sysop]

←Older revision

Revision as of 23:10, 7 January 2013

OCA at 23:10, 7 January 2013

2013-01-07T23:10:14Z

←Older revision		Revision as of 23:10, 7 January 2013
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-	{{Seed}}
	[[Image:3brz.png\|left\|200px]]		[[Image:3brz.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3brz", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3brz\| PDB=3brz \| SCENE= }}		{{STRUCTURE_3brz\| PDB=3brz \| SCENE= }}

	===Crystal structure of the Pseudomonas putida toluene transporter TodX===		===Crystal structure of the Pseudomonas putida toluene transporter TodX===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18559855}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18559855 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18559855}}		{{ABSTRACT_PUBMED_18559855}}

	==About this Structure==		==About this Structure==
-	~~3BRZ~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA].	+	[[3brz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18559855~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018559855</ref><references group="xtra"/>
	[[Category: Pseudomonas putida]]		[[Category: Pseudomonas putida]]
	[[Category: Berg, B van den.]]		[[Category: Berg, B van den.]]
Line 31:		Line 19:
	[[Category: Outer membrane protein]]		[[Category: Outer membrane protein]]
	[[Category: Transport protein]]		[[Category: Transport protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:35:26 2009''

OCA at 01:35, 18 February 2009

2009-02-18T01:35:29Z

←Older revision		Revision as of 01:35, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	3BRZ is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA].	+	3BRZ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA].

	==Reference==		==Reference==
-	~~Outer-membrane transport of aromatic hydrocarbons as a first step in biodegradation., Hearn EM, Patel DR, van den Berg B, Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8601-6. Epub 2008 Jun 16.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18559855 18559855]~~	+	<ref group="xtra">PMID:18559855</ref><references group="xtra"/>
	[[Category: Pseudomonas putida]]		[[Category: Pseudomonas putida]]
-	[[Category: Single protein]]
	[[Category: Berg, B van den.]]		[[Category: Berg, B van den.]]
	[[Category: Hearn, E M.]]		[[Category: Hearn, E M.]]
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	[[Category: Transport protein]]		[[Category: Transport protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jul 16 08~~:47:26 ~~2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:35:26 2009''

OCA at 05:47, 16 July 2008

2008-07-16T05:47:26Z

←Older revision		Revision as of 05:47, 16 July 2008
Line 1:		Line 1:
-	[[Image:3brz.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:3brz.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_3brz\| PDB=3brz \| SCENE= }}		{{STRUCTURE_3brz\| PDB=3brz \| SCENE= }}

-	~~'''~~Crystal structure of the Pseudomonas putida toluene transporter TodX~~'''~~	+	===Crystal structure of the Pseudomonas putida toluene transporter TodX===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_18559855}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18559855 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18559855}}

	==About this Structure==		==About this Structure==
	3BRZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA].		3BRZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRZ OCA].
		+
		+	==Reference==
		+	Outer-membrane transport of aromatic hydrocarbons as a first step in biodegradation., Hearn EM, Patel DR, van den Berg B, Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8601-6. Epub 2008 Jun 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18559855 18559855]
	[[Category: Pseudomonas putida]]		[[Category: Pseudomonas putida]]
	[[Category: Single protein]]		[[Category: Single protein]]
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	[[Category: Outer membrane protein]]		[[Category: Outer membrane protein]]
	[[Category: Transport protein]]		[[Category: Transport protein]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 11 10~~:47:52 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 16 08:47:26 2008''