3bwh - Revision history

OCA at 12:17, 30 August 2023

2023-08-30T12:17:20Z

←Older revision		Revision as of 12:17, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='3bwh' size='340' side='right'caption='[[3bwh]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='3bwh' size='340' side='right'caption='[[3bwh]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3bwh]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3BWH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3bwh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BWH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=~~PO4~~:~~PHOSPHATE+ION~~'>~~PO4~~</scene>, <scene name='pdbligand=~~MAN~~:~~ALPHA~~-D-~~MANNOSE~~'>~~MAN~~</scene>, <scene name='pdbligand=~~NAG~~:~~N-ACETYL-D-GLUCOSAMINE~~'>~~NAG~~</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3bwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwh OCA], [~~http~~://pdbe.org/3bwh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3bwh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3bwh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3bwh ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwh OCA], [https://pdbe.org/3bwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bwh RCSB], [https://www.ebi.ac.uk/pdbsum/3bwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bwh ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/D0VWS7_CUCMO D0VWS7_CUCMO]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 35:
	[[Category: Cucurbita moschata]]		[[Category: Cucurbita moschata]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chen, L]]	+	[[Category: Chen L]]
-	~~[[Category: Rip fold]]~~	+
-	~~[[Category: Translation~~]]	+

OCA at 06:20, 5 August 2020

2020-08-05T06:20:58Z

←Older revision		Revision as of 06:20, 5 August 2020
Line 1:		Line 1:

	==Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata==		==Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata==
-	<StructureSection load='3bwh' size='340' side='right' caption='[[3bwh]], [[Resolution\|resolution]] 1.00Å' scene=''>	+	<StructureSection load='3bwh' size='340' side='right'caption='[[3bwh]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3bwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3BWH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3bwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3BWH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=~~MAN~~:~~ALPHA-D-MANNOSE~~'>~~MAN~~</scene>, <scene name='pdbligand=~~NAG~~:~~N-ACETYL~~-D-~~GLUCOSAMINE~~'>~~NAG~~</scene>, <scene name='pdbligand=~~PO4~~:~~PHOSPHATE+ION~~'>~~PO4~~</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3bwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwh OCA], [http://pdbe.org/3bwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bwh RCSB], [http://www.ebi.ac.uk/pdbsum/3bwh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bwh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3bwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwh OCA], [http://pdbe.org/3bwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bwh RCSB], [http://www.ebi.ac.uk/pdbsum/3bwh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bwh ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Cucurbita moschata]]		[[Category: Cucurbita moschata]]
		+	[[Category: Large Structures]]
	[[Category: Chen, L]]		[[Category: Chen, L]]
	[[Category: Rip fold]]		[[Category: Rip fold]]
	[[Category: Translation]]		[[Category: Translation]]

OCA at 08:07, 31 October 2018

2018-10-31T08:07:09Z

←Older revision		Revision as of 08:07, 31 October 2018
Line 1:		Line 1:
		+
	==Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata==		==Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata==
	<StructureSection load='3bwh' size='340' side='right' caption='[[3bwh]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='3bwh' size='340' side='right' caption='[[3bwh]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BWH FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BWH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=~~PO4~~:~~PHOSPHATE+ION~~'>~~PO4~~</scene>, <scene name='pdbligand=~~MAN~~:~~ALPHA~~-D-~~MANNOSE~~'>~~MAN~~</scene>, <scene name='pdbligand=~~NAG~~:~~N-ACETYL-D-GLUCOSAMINE~~'>~~NAG~~</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwh OCA], [http://pdbe.org/3bwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bwh RCSB], [http://www.ebi.ac.uk/pdbsum/3bwh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwh OCA], [http://pdbe.org/3bwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bwh RCSB], [http://www.ebi.ac.uk/pdbsum/3bwh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bwh ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bw/3bwh_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bw/3bwh_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 09:20, 7 February 2016

2016-02-07T09:20:39Z

←Older revision		Revision as of 09:20, 7 February 2016
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[3bwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BWH FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BWH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bwh RCSB], [http://www.ebi.ac.uk/pdbsum/3bwh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwh OCA], [http://pdbe.org/3bwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bwh RCSB], [http://www.ebi.ac.uk/pdbsum/3bwh PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bwh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3bwh" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:36, 20 January 2015

2015-01-20T11:36:22Z

←Older revision		Revision as of 11:36, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BWH FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BWH FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bwh RCSB], [http://www.ebi.ac.uk/pdbsum/3bwh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bwh RCSB], [http://www.ebi.ac.uk/pdbsum/3bwh PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Cucurbita moschata]]		[[Category: Cucurbita moschata]]
-	[[Category: Chen, L.]]	+	[[Category: Chen, L]]
	[[Category: Rip fold]]		[[Category: Rip fold]]
	[[Category: Translation]]		[[Category: Translation]]

OCA at 21:23, 2 October 2014

2014-10-02T21:23:08Z

←Older revision		Revision as of 21:23, 2 October 2014
Line 1:		Line 1:
-	[[~~Image~~:3bwh.~~png\|left~~\|200px]]	+	==Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata==
		+	<StructureSection load='3bwh' size='340' side='right' caption='[[3bwh]], [[Resolution\|resolution]] 1.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3bwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BWH FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bwh RCSB], [http://www.ebi.ac.uk/pdbsum/3bwh PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bw/3bwh_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A novel type 1 ribosome-inactivating protein (RIP) designated cucurmosin was isolated from the sarcocarp of Cucurbita moschata (pumpkin). Besides rRNA N-glycosidase activity, cucurmosin exhibits strong cytotoxicities to three cancer cell lines of both human and murine origins, but low toxicity to normal cells. Plant genomic DNA extracted from the tender leaves was amplified by PCR between primers based on the N-terminal sequence and X-ray sequence of the C-terminal. The complete mature protein sequence was obtained from N-terminal protein sequencing and partial DNA sequencing, confirmed by high resolution crystal structure analysis. The crystal structure of cucurmosin has been determined at 1.04A, a resolution that has never been achieved before for any RIP. The structure contains two domains: a large N-terminal domain composed of seven alpha-helices and eight beta-strands, and a smaller C-terminal domain consisting of three alpha-helices and two beta-strands. The high resolution structure established a glycosylation pattern of GlcNAc(2)Man(3)Xyl. Asn225 was identified as a glycosylation site. Residues Tyr70, Tyr109, Glu158 and Arg161 define the active site of cucurmosin as an RNA N-glycosidase. The structural basis of cytotoxicity difference between cucurmosin and trichosanthin is discussed.

-	~~{{STRUCTURE_3bwh\| PDB=3bwh \| SCENE= }}~~	+	Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata.,Hou X, Meehan EJ, Xie J, Huang M, Chen M, Chen L J Struct Biol. 2008 Oct;164(1):81-7. Epub 2008 Jul 4. PMID:18652900<ref>PMID:18652900</ref>

-	~~===Atomic resolution structure of cucurmosin~~, a ~~novel type 1 RIP from~~ the ~~sarcocarp of Cucurbita moschata===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18652900}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3bwh]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Cucurbita_moschata Cucurbita moschata]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018652900<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Cucurbita moschata]]		[[Category: Cucurbita moschata]]
	[[Category: Chen, L.]]		[[Category: Chen, L.]]
	[[Category: Rip fold]]		[[Category: Rip fold]]
	[[Category: Translation]]		[[Category: Translation]]

OCA at 13:26, 6 February 2013

2013-02-06T13:26:10Z

←Older revision		Revision as of 13:26, 6 February 2013
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	[[Image:3bwh.png\|left\|200px]]		[[Image:3bwh.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3bwh\| PDB=3bwh \| SCENE= }}		{{STRUCTURE_3bwh\| PDB=3bwh \| SCENE= }}

	===Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata===		===Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata===

-
-	<!--
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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18652900~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018652900</ref><references group="xtra"/>
	[[Category: Cucurbita moschata]]		[[Category: Cucurbita moschata]]
	[[Category: Chen, L.]]		[[Category: Chen, L.]]
		+	[[Category: Rip fold]]
		+	[[Category: Translation]]

OCA: Protected "3bwh" [edit=sysop:move=sysop]

2011-03-16T07:27:02Z

Protected "3bwh" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:27, 16 March 2011

OCA at 07:27, 16 March 2011

2011-03-16T07:27:00Z

←Older revision		Revision as of 07:27, 16 March 2011
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-	{{Seed}}
	[[Image:3bwh.png\|left\|200px]]		[[Image:3bwh.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~3BWH~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA].	+	[[3bwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA].

	==Reference==		==Reference==
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	[[Category: Cucurbita moschata]]		[[Category: Cucurbita moschata]]
	[[Category: Chen, L.]]		[[Category: Chen, L.]]
-	[[Category: Rip fold]]
-	[[Category: Translation]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:51:30 2009''

OCA at 10:51, 16 February 2009

2009-02-16T10:51:32Z

←Older revision		Revision as of 10:51, 16 February 2009
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	{{Seed}}		{{Seed}}
-	[[Image:3bwh.~~jpg~~\|left\|200px]]	+	[[Image:3bwh.png\|left\|200px]]

	<!--		<!--
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	==About this Structure==		==About this Structure==
-	3BWH is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA].	+	3BWH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Cucurbita_moschata Cucurbita moschata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWH OCA].

	==Reference==		==Reference==
-	Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata., Hou X, Meehan EJ, Xie J, Huang M, Chen M, Chen L, J Struct Biol. 2008 Oct;164(1):81-7. Epub 2008 Jul 4. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18652900 18652900]~~	+	<ref group="xtra">PMID:18652900</ref><references group="xtra"/>
	[[Category: Cucurbita moschata]]		[[Category: Cucurbita moschata]]
-	[[Category: Single protein]]
	[[Category: Chen, L.]]		[[Category: Chen, L.]]
	[[Category: Rip fold]]		[[Category: Rip fold]]
	[[Category: Translation]]		[[Category: Translation]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Oct 8 09~~:26:~~21 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:51:30 2009''