3cqr - Revision history

OCA at 07:42, 2 February 2022

2022-02-02T07:42:20Z

←Older revision		Revision as of 07:42, 2 February 2022
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	==Crystal Structure of the Lipocalin domain of Violaxanthin de-epoxidase (VDE) at pH5==		==Crystal Structure of the Lipocalin domain of Violaxanthin de-epoxidase (VDE) at pH5==
-	<StructureSection load='3cqr' size='340' side='right' caption='[[3cqr]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3cqr' size='340' side='right'caption='[[3cqr]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3cqr]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3CQR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3cqr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CQR FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GD:GADOLINIUM+ATOM'>GD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GD:GADOLINIUM+ATOM'>GD</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3cqn\|3cqn]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3cqn\|3cqn]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">VDE1, AVDE1, NPQ1, VXDE ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">VDE1, AVDE1, NPQ1, VXDE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Violaxanthin_de-epoxidase Violaxanthin de-epoxidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.23.5.1 1.23.5.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Violaxanthin_de-epoxidase Violaxanthin de-epoxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.23.5.1 1.23.5.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3cqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqr OCA], [~~http~~://pdbe.org/3cqr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3cqr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3cqr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3cqr ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqr OCA], [https://pdbe.org/3cqr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cqr RCSB], [https://www.ebi.ac.uk/pdbsum/3cqr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cqr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/VDE_ARATH VDE_ARATH]] Part of the xanthophyll (or violaxanthin) cycle for controlling the concentration of zeaxanthin in chloroplasts. Catalyzes the two-step mono de-epoxidation reaction. Stereospecific for all-trans xanthophylls. Zeaxanthin induces the dissipation of excitation energy in the chlorophyll of the light-harvesting protein complex of photosystem II.<ref>PMID:10982442</ref> <ref>PMID:11855651</ref> <ref>PMID:9668132</ref>	+	[[https://www.uniprot.org/uniprot/VDE_ARATH VDE_ARATH]] Part of the xanthophyll (or violaxanthin) cycle for controlling the concentration of zeaxanthin in chloroplasts. Catalyzes the two-step mono de-epoxidation reaction. Stereospecific for all-trans xanthophylls. Zeaxanthin induces the dissipation of excitation energy in the chlorophyll of the light-harvesting protein complex of photosystem II.<ref>PMID:10982442</ref> <ref>PMID:11855651</ref> <ref>PMID:9668132</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Arath]]		[[Category: Arath]]
		+	[[Category: Large Structures]]
	[[Category: Violaxanthin de-epoxidase]]		[[Category: Violaxanthin de-epoxidase]]
	[[Category: Arnoux, P]]		[[Category: Arnoux, P]]

OCA at 13:54, 7 November 2018

2018-11-07T13:54:41Z

←Older revision		Revision as of 13:54, 7 November 2018
Line 1:		Line 1:
		+
	==Crystal Structure of the Lipocalin domain of Violaxanthin de-epoxidase (VDE) at pH5==		==Crystal Structure of the Lipocalin domain of Violaxanthin de-epoxidase (VDE) at pH5==
	<StructureSection load='3cqr' size='340' side='right' caption='[[3cqr]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3cqr' size='340' side='right' caption='[[3cqr]], [[Resolution\|resolution]] 2.00Å' scene=''>
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	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">VDE1, AVDE1, NPQ1, VXDE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">VDE1, AVDE1, NPQ1, VXDE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Violaxanthin_de-epoxidase Violaxanthin de-epoxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.23.5.1 1.23.5.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Violaxanthin_de-epoxidase Violaxanthin de-epoxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.23.5.1 1.23.5.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqr OCA], [http://pdbe.org/3cqr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cqr RCSB], [http://www.ebi.ac.uk/pdbsum/3cqr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqr OCA], [http://pdbe.org/3cqr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cqr RCSB], [http://www.ebi.ac.uk/pdbsum/3cqr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cqr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cq/3cqr_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cq/3cqr_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 15:27, 8 February 2016

2016-02-08T15:27:29Z

←Older revision		Revision as of 15:27, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='3cqr' size='340' side='right' caption='[[3cqr]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3cqr' size='340' side='right' caption='[[3cqr]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3cqr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Arabidopsis_thaliana Arabidopsis thaliana~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CQR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3cqr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CQR FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GD:GADOLINIUM+ATOM'>GD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GD:GADOLINIUM+ATOM'>GD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3cqn\|3cqn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3cqn\|3cqn]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">VDE1, AVDE1, NPQ1, VXDE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ~~Arabidopsis thaliana~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">VDE1, AVDE1, NPQ1, VXDE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Violaxanthin_de-epoxidase Violaxanthin de-epoxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.99.3 1.10.99.3] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Violaxanthin_de-epoxidase Violaxanthin de-epoxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.23.5.1 1.23.5.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cqr RCSB], [http://www.ebi.ac.uk/pdbsum/3cqr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqr OCA], [http://pdbe.org/3cqr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cqr RCSB], [http://www.ebi.ac.uk/pdbsum/3cqr PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cqr ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3cqr" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arabidopsis thaliana~~]]	+	[[Category: Arath]]
	[[Category: Violaxanthin de-epoxidase]]		[[Category: Violaxanthin de-epoxidase]]
	[[Category: Arnoux, P]]		[[Category: Arnoux, P]]

OCA at 00:20, 25 December 2014

2014-12-25T00:20:22Z

←Older revision		Revision as of 00:20, 25 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cqr RCSB], [http://www.ebi.ac.uk/pdbsum/3cqr PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cqr RCSB], [http://www.ebi.ac.uk/pdbsum/3cqr PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/VDE_ARATH VDE_ARATH]] Part of the xanthophyll (or violaxanthin) cycle for controlling the concentration of zeaxanthin in chloroplasts. Catalyzes the two-step mono de-epoxidation reaction. Stereospecific for all-trans xanthophylls. Zeaxanthin induces the dissipation of excitation energy in the chlorophyll of the light-harvesting protein complex of photosystem II.<ref>PMID:10982442</ref> <ref>PMID:11855651</ref> <ref>PMID:9668132</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Violaxanthin de-epoxidase]]		[[Category: Violaxanthin de-epoxidase]]
-	[[Category: Arnoux, P.]]	+	[[Category: Arnoux, P]]
-	[[Category: Morosinotto, T.]]	+	[[Category: Morosinotto, T]]
-	[[Category: Pignol, D.]]	+	[[Category: Pignol, D]]
	[[Category: Antheraxanthin]]		[[Category: Antheraxanthin]]
	[[Category: Chloroplast]]		[[Category: Chloroplast]]

OCA at 06:48, 10 October 2014

2014-10-10T06:48:34Z

←Older revision		Revision as of 06:48, 10 October 2014
Line 1:		Line 1:
-	[[~~Image:~~3cqr.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of the Lipocalin domain of Violaxanthin de-epoxidase (VDE) at pH5==
		+	<StructureSection load='3cqr' size='340' side='right' caption='[[3cqr]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3cqr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CQR FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GD:GADOLINIUM+ATOM'>GD</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3cqn\|3cqn]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">VDE1, AVDE1, NPQ1, VXDE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Violaxanthin_de-epoxidase Violaxanthin de-epoxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.99.3 1.10.99.3] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cqr RCSB], [http://www.ebi.ac.uk/pdbsum/3cqr PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cq/3cqr_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Plants adjust their photosynthetic activity to changing light conditions. A central regulation of photosynthesis depends on the xanthophyll cycle, in which the carotenoid violaxanthin is converted into zeaxanthin in strong light, thus activating the dissipation of the excess absorbed energy as heat and the scavenging of reactive oxygen species. Violaxanthin deepoxidase (VDE), the enzyme responsible for zeaxanthin synthesis, is activated by the acidification of the thylakoid lumen when photosynthetic electron transport exceeds the capacity of assimilatory reactions: at neutral pH, VDE is a soluble and inactive enzyme, whereas at acidic pH, it attaches to the thylakoid membrane where it binds its violaxanthin substrate. VDE also uses ascorbate as a cosubstrate with a pH-dependent Km that may reflect a preference for ascorbic acid. We determined the structures of the central lipocalin domain of VDE (VDEcd) at acidic and neutral pH. At neutral pH, VDEcd is monomeric with its active site occluded within a lipocalin barrel. Upon acidification, the barrel opens up and the enzyme appears as a dimer. A channel linking the two active sites of the dimer can harbor the entire carotenoid substrate and thus may permit the parallel deepoxidation of the two violaxanthin beta-ionone rings, making VDE an elegant example of the adaptation of an asymmetric enzyme to its symmetric substrate.

-	~~{{STRUCTURE_3cqr\| PDB=3cqr \| SCENE= }}~~	+	A structural basis for the pH-dependent xanthophyll cycle in Arabidopsis thaliana.,Arnoux P, Morosinotto T, Saga G, Bassi R, Pignol D Plant Cell. 2009 Jul;21(7):2036-44. Epub 2009 Jul 28. PMID:19638474<ref>PMID:19638474</ref>

-	~~===Crystal Structure~~ of the ~~Lipocalin domain~~ of ~~Violaxanthin de-epoxidase (VDE) at pH5===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19638474}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[3cqr]] is a 2 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQR OCA].~~	+	</StructureSection>
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Violaxanthin de-epoxidase]]		[[Category: Violaxanthin de-epoxidase]]

OCA: Protected "3cqr" [edit=sysop:move=sysop]

2013-01-02T07:50:03Z

Protected "3cqr" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:50, 2 January 2013

OCA at 07:50, 2 January 2013

2013-01-02T07:50:01Z

←Older revision		Revision as of 07:50, 2 January 2013
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-	~~{{Seed}}~~	+	[[Image:3cqr.png\|left\|200px]]
-	[[Image:3cqr.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3cqr", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3cqr\| PDB=3cqr \| SCENE= }}		{{STRUCTURE_3cqr\| PDB=3cqr \| SCENE= }}

	===Crystal Structure of the Lipocalin domain of Violaxanthin de-epoxidase (VDE) at pH5===		===Crystal Structure of the Lipocalin domain of Violaxanthin de-epoxidase (VDE) at pH5===

		+	{{ABSTRACT_PUBMED_19638474}}

	==About this Structure==		==About this Structure==
-	~~3CQR~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQR OCA].	+	[[3cqr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQR OCA].
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Violaxanthin de-epoxidase]]		[[Category: Violaxanthin de-epoxidase]]
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	[[Category: Antheraxanthin]]		[[Category: Antheraxanthin]]
	[[Category: Chloroplast]]		[[Category: Chloroplast]]
-	[[Category: Coiled coil]]
	[[Category: De-epoxidase]]		[[Category: De-epoxidase]]
	[[Category: Enzyme]]		[[Category: Enzyme]]
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	[[Category: Npq]]		[[Category: Npq]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-	[[Category: Plastid]]
	[[Category: Thylakoid]]		[[Category: Thylakoid]]
	[[Category: Transit peptide]]		[[Category: Transit peptide]]
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	[[Category: Xanthophyll cycle]]		[[Category: Xanthophyll cycle]]
	[[Category: Zeaxanthin]]		[[Category: Zeaxanthin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 11:28:57 2009''

OCA at 08:28, 22 April 2009

2009-04-22T08:28:59Z

←Older revision		Revision as of 08:28, 22 April 2009
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3cqr.jpg\|left\|200px]]

-	The ~~entry 3cqr~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3cqr", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3cqr\| PDB=3cqr \| SCENE= }}

-	~~Authors: Arnoux, P., Morosinotto, T., Pignol, D.~~	+	===Crystal Structure of the Lipocalin domain of Violaxanthin de-epoxidase (VDE) at pH5===

-	Description: Crystal Structure of the Lipocalin domain of Violaxanthin de-epoxidase (VDE) at pH5

		+	==About this Structure==
		+	3CQR is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQR OCA].
		+	[[Category: Arabidopsis thaliana]]
		+	[[Category: Violaxanthin de-epoxidase]]
		+	[[Category: Arnoux, P.]]
		+	[[Category: Morosinotto, T.]]
		+	[[Category: Pignol, D.]]
		+	[[Category: Antheraxanthin]]
		+	[[Category: Chloroplast]]
		+	[[Category: Coiled coil]]
		+	[[Category: De-epoxidase]]
		+	[[Category: Enzyme]]
		+	[[Category: Lipocalin]]
		+	[[Category: Membrane]]
		+	[[Category: Non photochemical quenching]]
		+	[[Category: Npq]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Plastid]]
		+	[[Category: Thylakoid]]
		+	[[Category: Transit peptide]]
		+	[[Category: Violaxanthin]]
		+	[[Category: Xanthophyll cycle]]
		+	[[Category: Zeaxanthin]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun~~ 11 09:33:~~32 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 11:28:57 2009''

OCA: New page: '''Unreleased structure''' The entry 3cqr is ON HOLD until Paper Publication Authors: Arnoux, P., Morosinotto, T., Pignol, D. Description: Crystal Structure of the Lipocalin domain of ...

2008-06-11T06:33:32Z

New page: '''Unreleased structure''' The entry 3cqr is ON HOLD until Paper Publication Authors: Arnoux, P., Morosinotto, T., Pignol, D. Description: Crystal Structure of the Lipocalin domain of ...

New page

'''Unreleased structure'''

The entry 3cqr is ON HOLD until Paper Publication

Authors: Arnoux, P., Morosinotto, T., Pignol, D.

Description: Crystal Structure of the Lipocalin domain of Violaxanthin de-epoxidase (VDE) at pH5

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:33:32 2008''