3cz7 - Revision history

OCA at 07:48, 2 February 2022

2022-02-02T07:48:33Z

←Older revision		Revision as of 07:48, 2 February 2022
Line 1:		Line 1:

	==Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109==		==Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109==
-	<StructureSection load='3cz7' size='340' side='right' caption='[[3cz7]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3cz7' size='340' side='right'caption='[[3cz7]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3cz7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3CZ7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3cz7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CZ7 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RTT109, KIM2, REM50 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RTT109, KIM2, REM50 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3cz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz7 OCA], [~~http~~://pdbe.org/3cz7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3cz7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3cz7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3cz7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz7 OCA], [https://pdbe.org/3cz7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cz7 RCSB], [https://www.ebi.ac.uk/pdbsum/3cz7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cz7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RT109_YEAST RT109_YEAST]] Required for acetylation of 'Lys-56' of histone H3 (H3K56ac) which occurs in S phase and disappears during G(2)/M phase of the cell cycle and is involved in transcription DNA repair process. H3K56 acetylation weakens of the interaction between the histone core and the surrounding DNA in the nucleosomal particle and drives chromatin disassembly. Involved in regulation of Ty1 transposition.<ref>PMID:11779788</ref> <ref>PMID:17046836</ref> <ref>PMID:17369253</ref> <ref>PMID:17690098</ref> <ref>PMID:17320445</ref> <ref>PMID:17272722</ref> <ref>PMID:17272723</ref> <ref>PMID:18577595</ref> <ref>PMID:18723682</ref>	+	[[https://www.uniprot.org/uniprot/RT109_YEAST RT109_YEAST]] Required for acetylation of 'Lys-56' of histone H3 (H3K56ac) which occurs in S phase and disappears during G(2)/M phase of the cell cycle and is involved in transcription DNA repair process. H3K56 acetylation weakens of the interaction between the histone core and the surrounding DNA in the nucleosomal particle and drives chromatin disassembly. Involved in regulation of Ty1 transposition.<ref>PMID:11779788</ref> <ref>PMID:17046836</ref> <ref>PMID:17369253</ref> <ref>PMID:17690098</ref> <ref>PMID:17320445</ref> <ref>PMID:17272722</ref> <ref>PMID:17272723</ref> <ref>PMID:18577595</ref> <ref>PMID:18723682</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/3cz7_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/3cz7_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Hoelz, A]]		[[Category: Hoelz, A]]
	[[Category: Stavropoulos, P]]		[[Category: Stavropoulos, P]]
	[[Category: Chromatin stability]]		[[Category: Chromatin stability]]
	[[Category: Replication]]		[[Category: Replication]]

OCA at 00:41, 16 November 2017

2017-11-16T00:41:42Z

←Older revision		Revision as of 00:41, 16 November 2017
Line 1:		Line 1:
		+
	==Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109==		==Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109==
	<StructureSection load='3cz7' size='340' side='right' caption='[[3cz7]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3cz7' size='340' side='right' caption='[[3cz7]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3cz7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CZ7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3cz7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CZ7 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RTT109, KIM2, REM50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ~~Saccharomyces cerevisiae~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RTT109, KIM2, REM50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz7 OCA], [http://pdbe.org/3cz7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cz7 RCSB], [http://www.ebi.ac.uk/pdbsum/3cz7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz7 OCA], [http://pdbe.org/3cz7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cz7 RCSB], [http://www.ebi.ac.uk/pdbsum/3cz7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cz7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae~~]]	+	[[Category: Atcc 18824]]
	[[Category: Hoelz, A]]		[[Category: Hoelz, A]]
	[[Category: Stavropoulos, P]]		[[Category: Stavropoulos, P]]
	[[Category: Chromatin stability]]		[[Category: Chromatin stability]]
	[[Category: Replication]]		[[Category: Replication]]

OCA at 05:17, 8 February 2016

2016-02-08T05:17:00Z

←Older revision		Revision as of 05:17, 8 February 2016
Line 6:		Line 6:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RTT109, KIM2, REM50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RTT109, KIM2, REM50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cz7 RCSB], [http://www.ebi.ac.uk/pdbsum/3cz7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz7 OCA], [http://pdbe.org/3cz7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cz7 RCSB], [http://www.ebi.ac.uk/pdbsum/3cz7 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cz7 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3cz7" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 20:54, 24 December 2014

2014-12-24T20:54:04Z

←Older revision		Revision as of 20:54, 24 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cz7 RCSB], [http://www.ebi.ac.uk/pdbsum/3cz7 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cz7 RCSB], [http://www.ebi.ac.uk/pdbsum/3cz7 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RT109_YEAST RT109_YEAST]] Required for acetylation of 'Lys-56' of histone H3 (H3K56ac) which occurs in S phase and disappears during G(2)/M phase of the cell cycle and is involved in transcription DNA repair process. H3K56 acetylation weakens of the interaction between the histone core and the surrounding DNA in the nucleosomal particle and drives chromatin disassembly. Involved in regulation of Ty1 transposition.<ref>PMID:11779788</ref> <ref>PMID:17046836</ref> <ref>PMID:17369253</ref> <ref>PMID:17690098</ref> <ref>PMID:17320445</ref> <ref>PMID:17272722</ref> <ref>PMID:17272723</ref> <ref>PMID:18577595</ref> <ref>PMID:18723682</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Hoelz, A.]]	+	[[Category: Hoelz, A]]
-	[[Category: Stavropoulos, P.]]	+	[[Category: Stavropoulos, P]]
	[[Category: Chromatin stability]]		[[Category: Chromatin stability]]
	[[Category: Replication]]		[[Category: Replication]]

OCA at 09:33, 5 November 2014

2014-11-05T09:33:04Z

←Older revision		Revision as of 09:33, 5 November 2014
Line 1:		Line 1:
-	[[~~Image:~~3cz7.~~png~~\|~~left~~\|200px]]	+	==Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109==
		+	<StructureSection load='3cz7' size='340' side='right' caption='[[3cz7]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3cz7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CZ7 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RTT109, KIM2, REM50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cz7 RCSB], [http://www.ebi.ac.uk/pdbsum/3cz7 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/3cz7_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rtt109 is a protein acetyltransferase (PAT) that is responsible for the acetylation of lysine-56 of histone 3 (H3K56) in yeast. H3K56 acetylation has been implicated in the weakening of the interaction between the histone core and the surrounding DNA in the nucleosomal particle. Rtt109, in cooperation with various histone chaperones, promotes genomic stability and is required for resistance to DNA damaging agents. Here, we present the crystal structure of Rtt109 in complex with acetyl-CoA at a 2.0-A resolution. Rtt109 consists of a core PAT domain, which binds the acetyl-CoA cofactor. A second domain, the activation domain, is tightly associated with the PAT domain. Autoacetylation of lysine-290 within the activation domain is required for stabilizing the interaction between the two domains and is essential for catalysis. Biochemical analysis demonstrates the requirement of a loop within the PAT domain for the binding of the histone chaperone Vps75, and mutational analysis identifies key residues for catalysis. We propose a model in which the autoacetylation of Rtt109 is crucial for the regulation of its catalytic activity.

-	~~{{STRUCTURE_3cz7\| PDB=3cz7 \| SCENE= }}~~	+	Molecular basis for the autoregulation of the protein acetyl transferase Rtt109.,Stavropoulos P, Nagy V, Blobel G, Hoelz A Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12236-41. Epub 2008 Aug 21. PMID:18719104<ref>PMID:18719104</ref>

-	~~===Molecular Basis for the Autoregulation~~ of the ~~Protein Acetyl Transferase Rtt109===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18719104}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3cz7]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ7 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018719104<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Hoelz, A.]]		[[Category: Hoelz, A.]]

OCA: Protected "3cz7" [edit=sysop:move=sysop]

2013-01-07T21:50:37Z

Protected "3cz7" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:50, 7 January 2013

OCA at 21:50, 7 January 2013

2013-01-07T21:50:35Z

←Older revision		Revision as of 21:50, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3cz7.png\|left\|200px]]		[[Image:3cz7.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3cz7", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3cz7\| PDB=3cz7 \| SCENE= }}		{{STRUCTURE_3cz7\| PDB=3cz7 \| SCENE= }}

	===Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109===		===Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18719104}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18719104 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18719104}}		{{ABSTRACT_PUBMED_18719104}}

	==About this Structure==		==About this Structure==
-	~~3CZ7~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ7 OCA].	+	[[3cz7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ7 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18719104~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018719104</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Hoelz, A.]]		[[Category: Hoelz, A.]]
Line 29:		Line 17:
	[[Category: Chromatin stability]]		[[Category: Chromatin stability]]
	[[Category: Replication]]		[[Category: Replication]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:05:25 2009''

OCA at 17:05, 16 February 2009

2009-02-16T17:05:25Z

←Older revision		Revision as of 17:05, 16 February 2009
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3cz7.~~jpg~~\|left\|200px]]	+	[[Image:3cz7.png\|left\|200px]]

	<!--		<!--
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	3CZ7 is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ7 OCA].	+	3CZ7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ7 OCA].

	==Reference==		==Reference==
-	~~Molecular basis for the autoregulation of the protein acetyl transferase Rtt109., Stavropoulos P, Nagy V, Blobel G, Hoelz A, Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12236-41. Epub 2008 Aug 21.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18719104 18719104]~~	+	<ref group="xtra">PMID:18719104</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Single protein]]
	[[Category: Hoelz, A.]]		[[Category: Hoelz, A.]]
	[[Category: Stavropoulos, P.]]		[[Category: Stavropoulos, P.]]
Line 31:		Line 30:
	[[Category: Replication]]		[[Category: Replication]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Sep 10 10~~:48:~~50 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:05:25 2009''

OCA at 07:48, 10 September 2008

2008-09-10T07:48:50Z

←Older revision		Revision as of 07:48, 10 September 2008
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3cz7.jpg\|left\|200px]]

-	The ~~entry 3cz7~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3cz7", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3cz7\| PDB=3cz7 \| SCENE= }}

-	~~Authors: Hoelz, A., Stavropoulos, P.~~	+	===Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109===

-	Description: Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Aug 6 12~~:25:41 2008''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_18719104}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18719104 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18719104}}
		+
		+	==About this Structure==
		+	3CZ7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ7 OCA].
		+
		+	==Reference==
		+	Molecular basis for the autoregulation of the protein acetyl transferase Rtt109., Stavropoulos P, Nagy V, Blobel G, Hoelz A, Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12236-41. Epub 2008 Aug 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18719104 18719104]
		+	[[Category: Saccharomyces cerevisiae]]
		+	[[Category: Single protein]]
		+	[[Category: Hoelz, A.]]
		+	[[Category: Stavropoulos, P.]]
		+	[[Category: Chromatin stability]]
		+	[[Category: Replication]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 10 10:48:50 2008''

OCA at 09:25, 6 August 2008

2008-08-06T09:25:41Z

←Older revision		Revision as of 09:25, 6 August 2008
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3cz7 is ON HOLD	+	The entry 3cz7 is ON HOLD until Paper Publication

	Authors: Hoelz, A., Stavropoulos, P.		Authors: Hoelz, A., Stavropoulos, P.
Line 7:		Line 7:
	Description: Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109		Description: Molecular Basis for the Autoregulation of the Protein Acetyl Transferase Rtt109

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jul 23~~ 12:12:25 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 6 12:25:41 2008''