3d43 - Revision history

OCA at 12:40, 30 August 2023

2023-08-30T12:40:17Z

←Older revision		Revision as of 12:40, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='3d43' size='340' side='right'caption='[[3d43]], [[Resolution\|resolution]] 0.80Å' scene=''>		<StructureSection load='3d43' size='340' side='right'caption='[[3d43]], [[Resolution\|resolution]] 0.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3d43]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bacillus_sphaericus Bacillus~~ sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D43 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3d43]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D43 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 0.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2ixt\|2ixt]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d43 OCA], [https://pdbe.org/3d43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d43 RCSB], [https://www.ebi.ac.uk/pdbsum/3d43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d43 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d43 OCA], [https://pdbe.org/3d43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d43 RCSB], [https://www.ebi.ac.uk/pdbsum/3d43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d43 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9S3L6_LYSSH Q9S3L6_LYSSH]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus sphaericus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Almog, O~~]]	+	[[Category: Lysinibacillus sphaericus]]
-	[[Category: ~~Calcium binding]]~~	+	[[Category: Almog O]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Serin protease]]~~	+
-	~~[[Category: Serine protease~~]]	+

OCA at 07:53, 2 February 2022

2022-02-02T07:53:09Z

←Older revision		Revision as of 07:53, 2 February 2022
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	<StructureSection load='3d43' size='340' side='right'caption='[[3d43]], [[Resolution\|resolution]] 0.80Å' scene=''>		<StructureSection load='3d43' size='340' side='right'caption='[[3d43]], [[Resolution\|resolution]] 0.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3d43]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacillus_sphaericus Bacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3D43 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3d43]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sphaericus Bacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D43 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ixt\|2ixt]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ixt\|2ixt]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3d43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d43 OCA], [~~http~~://pdbe.org/3d43 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3d43 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3d43 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3d43 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d43 OCA], [https://pdbe.org/3d43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d43 RCSB], [https://www.ebi.ac.uk/pdbsum/3d43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d43 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Subtilisin\|Subtilisin]]	+	*[[Subtilisin 3D structures\|Subtilisin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:39, 31 July 2019

2019-07-31T07:39:16Z

←Older revision		Revision as of 07:39, 31 July 2019
Line 1:		Line 1:

	==The crystal structure of Sph at 0.8A==		==The crystal structure of Sph at 0.8A==
-	<StructureSection load='3d43' size='340' side='right' caption='[[3d43]], [[Resolution\|resolution]] 0.80Å' scene=''>	+	<StructureSection load='3d43' size='340' side='right'caption='[[3d43]], [[Resolution\|resolution]] 0.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3d43]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sphaericus Bacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D43 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3d43]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sphaericus Bacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D43 FirstGlance]. <br>
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/3d43_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/3d43_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 3d43" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3d43" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Subtilisin\|Subtilisin]]
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus sphaericus]]		[[Category: Bacillus sphaericus]]
		+	[[Category: Large Structures]]
	[[Category: Almog, O]]		[[Category: Almog, O]]
	[[Category: Calcium binding]]		[[Category: Calcium binding]]

OCA at 08:41, 25 October 2017

2017-10-25T08:41:59Z

←Older revision		Revision as of 08:41, 25 October 2017
Line 1:		Line 1:
		+
	==The crystal structure of Sph at 0.8A==		==The crystal structure of Sph at 0.8A==
	<StructureSection load='3d43' size='340' side='right' caption='[[3d43]], [[Resolution\|resolution]] 0.80Å' scene=''>		<StructureSection load='3d43' size='340' side='right' caption='[[3d43]], [[Resolution\|resolution]] 0.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3d43]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Lysinibacillus_sphaericus Lysinibacillus~~ sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D43 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3d43]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sphaericus Bacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D43 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ixt\|2ixt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ixt\|2ixt]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d43 OCA], [http://pdbe.org/3d43 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3d43 RCSB], [http://www.ebi.ac.uk/pdbsum/3d43 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d43 OCA], [http://pdbe.org/3d43 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3d43 RCSB], [http://www.ebi.ac.uk/pdbsum/3d43 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3d43 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</div>		</div>
	<div class="pdbe-citations 3d43" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3d43" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Subtilisin\|Subtilisin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Lysinibacillus~~ sphaericus]]	+	[[Category: Bacillus sphaericus]]
	[[Category: Almog, O]]		[[Category: Almog, O]]
	[[Category: Calcium binding]]		[[Category: Calcium binding]]

OCA at 18:33, 8 February 2016

2016-02-08T18:33:38Z

←Older revision		Revision as of 18:33, 8 February 2016
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ixt\|2ixt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ixt\|2ixt]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d43 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3d43 RCSB], [http://www.ebi.ac.uk/pdbsum/3d43 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d43 OCA], [http://pdbe.org/3d43 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3d43 RCSB], [http://www.ebi.ac.uk/pdbsum/3d43 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3d43 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3d43" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 09:24, 20 January 2015

2015-01-20T09:24:30Z

←Older revision		Revision as of 09:24, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3d43]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D43 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3d43]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D43 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ixt\|2ixt]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ixt\|2ixt]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d43 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3d43 RCSB], [http://www.ebi.ac.uk/pdbsum/3d43 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d43 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3d43 RCSB], [http://www.ebi.ac.uk/pdbsum/3d43 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
-	[[Category: Almog, O.]]	+	[[Category: Almog, O]]
	[[Category: Calcium binding]]		[[Category: Calcium binding]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Serin protease]]		[[Category: Serin protease]]
	[[Category: Serine protease]]		[[Category: Serine protease]]

OCA at 07:49, 29 September 2014

2014-09-29T07:49:13Z

←Older revision		Revision as of 07:49, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~3d43.~~png~~\|~~left~~\|200px]]	+	==The crystal structure of Sph at 0.8A==
		+	<StructureSection load='3d43' size='340' side='right' caption='[[3d43]], [[Resolution\|resolution]] 0.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3d43]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D43 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ixt\|2ixt]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d43 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3d43 RCSB], [http://www.ebi.ac.uk/pdbsum/3d43 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/3d43_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We determine and compare the crystal structure of two proteases belonging to the subtilisin superfamily: S41, a cold-adapted serine protease produced by Antarctic bacilli, at 1.4 A resolution and Sph, a mesophilic serine protease produced by Bacillus sphaericus, at 0.8 A resolution. The purpose of this comparison was to find out whether multiple calcium ion binding is a molecular factor responsible for the adaptation of S41 to extreme low temperatures. We find that these two subtilisins have the same subtilisin fold with a root mean square between the two structures of 0.54 A. The final models for S41 and Sph include a calcium-loaded state of five ions bound to each of these two subtilisin molecules. None of these calcium-binding sites correlate with the high affinity known binding site (site A) found for other subtilisins. Structural analysis of the five calcium-binding sites found in these two crystal structures indicate that three of the binding sites have two side chains of an acidic residue coordinating the calcium ion, whereas the other two binding sites have either a main-chain carbonyl, or only one acidic residue side chain coordinating the calcium ion. Thus, we conclude that three of the sites are of high affinity toward calcium ions, whereas the other two are of low affinity. Because Sph is a mesophilic subtilisin and S41 is a psychrophilic subtilisin, but both crystal structures were found to bind five calcium ions, we suggest that multiple calcium ion binding is not responsible for the adaptation of S41 to low temperatures.

-	~~{{STRUCTURE_3d43\| PDB=3d43 \| SCENE= }}~~	+	The crystal structures of the psychrophilic subtilisin S41 and the mesophilic subtilisin Sph reveal the same calcium-loaded state.,Almog O, Gonzalez A, Godin N, de Leeuw M, Mekel MJ, Klein D, Braun S, Shoham G, Walter RL Proteins. 2009 Feb 1;74(2):489-96. PMID:18655058<ref>PMID:18655058</ref>

-	~~===The crystal structure~~ of ~~Sph at 0~~.~~8A===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18655058}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3d43]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA].~~	+

	==See Also==		==See Also==
	*[[Subtilisin\|Subtilisin]]		*[[Subtilisin\|Subtilisin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:018655058<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
	[[Category: Almog, O.]]		[[Category: Almog, O.]]

OCA at 11:04, 20 October 2012

2012-10-20T11:04:57Z

←Older revision		Revision as of 11:04, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3d43]] is a 2 chain structure ~~of [[Subtilisin]]~~ with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA].	+	[[3d43]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D43 OCA].

	==See Also==		==See Also==

OCA at 04:11, 26 July 2012

2012-07-26T04:11:20Z

←Older revision		Revision as of 04:11, 26 July 2012
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	[[Image:3d43.png\|left\|200px]]		[[Image:3d43.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3d43\| PDB=3d43 \| SCENE= }}		{{STRUCTURE_3d43\| PDB=3d43 \| SCENE= }}

	===The crystal structure of Sph at 0.8A===		===The crystal structure of Sph at 0.8A===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18655058}}, adds the Publication Abstract to the page
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	==See Also==		==See Also==
-	*[[Subtilisin]]	+	*[[Subtilisin\|Subtilisin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18655058~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018655058</ref><references group="xtra"/>
	[[Category: Lysinibacillus sphaericus]]		[[Category: Lysinibacillus sphaericus]]
	[[Category: Almog, O.]]		[[Category: Almog, O.]]

OCA: Protected "3d43" [edit=sysop:move=sysop]

2010-12-27T01:31:19Z

Protected "3d43" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:31, 27 December 2010