3dgh - Revision history

OCA at 19:23, 20 October 2021

2021-10-20T19:23:29Z

←Older revision		Revision as of 19:23, 20 October 2021
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	==Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation==		==Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation==
-	<StructureSection load='3dgh' size='340' side='right' caption='[[3dgh]], [[Resolution\|resolution]] 1.75Å' scene=''>	+	<StructureSection load='3dgh' size='340' side='right'caption='[[3dgh]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3dgh]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3DGH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3dgh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DGH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nvk\|2nvk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2nvk\|2nvk]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Trxr-1, GR, CG2151 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Trxr-1, GR, CG2151 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3dgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgh OCA], [~~http~~://pdbe.org/3dgh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3dgh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3dgh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3dgh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgh OCA], [https://pdbe.org/3dgh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dgh RCSB], [https://www.ebi.ac.uk/pdbsum/3dgh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dgh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/TRXR1_DROME TRXR1_DROME]] Thioredoxin system is a major player in glutathione metabolism, due to the demonstrated absence of a glutathione reductase. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a glutathione reductase suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms.<ref>PMID:11158675</ref> <ref>PMID:11525742</ref> <ref>PMID:11796729</ref>	+	[[https://www.uniprot.org/uniprot/TRXR1_DROME TRXR1_DROME]] Thioredoxin system is a major player in glutathione metabolism, due to the demonstrated absence of a glutathione reductase. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a glutathione reductase suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms.<ref>PMID:11158675</ref> <ref>PMID:11525742</ref> <ref>PMID:11796729</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dg/3dgh_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dg/3dgh_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 22:		Line 22:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dgh ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dgh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+
		+	==See Also==
		+	*[[Thioredoxin reductase 3D structures\|Thioredoxin reductase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 27:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Drome]]		[[Category: Drome]]
		+	[[Category: Large Structures]]
	[[Category: Thioredoxin-disulfide reductase]]		[[Category: Thioredoxin-disulfide reductase]]
	[[Category: Eckenroth, B E]]		[[Category: Eckenroth, B E]]

OCA at 08:48, 25 October 2017

2017-10-25T08:48:57Z

←Older revision		Revision as of 08:48, 25 October 2017
Line 1:		Line 1:
		+
	==Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation==		==Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation==
	<StructureSection load='3dgh' size='340' side='right' caption='[[3dgh]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='3dgh' size='340' side='right' caption='[[3dgh]], [[Resolution\|resolution]] 1.75Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Trxr-1, GR, CG2151 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Trxr-1, GR, CG2151 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgh OCA], [http://pdbe.org/3dgh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dgh RCSB], [http://www.ebi.ac.uk/pdbsum/3dgh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgh OCA], [http://pdbe.org/3dgh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dgh RCSB], [http://www.ebi.ac.uk/pdbsum/3dgh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dgh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 21:		Line 22:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dgh ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dgh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-
-	==See Also==
-	*[[Thioredoxin Reductase\|Thioredoxin Reductase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:13, 7 February 2016

2016-02-07T07:13:48Z

←Older revision		Revision as of 07:13, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3dgh' size='340' side='right' caption='[[3dgh]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='3dgh' size='340' side='right' caption='[[3dgh]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3dgh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Drosophila_melanogaster Drosophila melanogaster~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DGH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3dgh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DGH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nvk\|2nvk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nvk\|2nvk]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Trxr-1, GR, CG2151 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 ~~Drosophila melanogaster~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Trxr-1, GR, CG2151 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dgh RCSB], [http://www.ebi.ac.uk/pdbsum/3dgh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgh OCA], [http://pdbe.org/3dgh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dgh RCSB], [http://www.ebi.ac.uk/pdbsum/3dgh PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dgh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

Line 28:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Drosophila melanogaster~~]]	+	[[Category: Drome]]
	[[Category: Thioredoxin-disulfide reductase]]		[[Category: Thioredoxin-disulfide reductase]]
	[[Category: Eckenroth, B E]]		[[Category: Eckenroth, B E]]

OCA at 08:54, 24 December 2014

2014-12-24T08:54:12Z

←Older revision		Revision as of 08:54, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3dgh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DGH FirstGlance]. <br>		<table><tr><td colspan='2'>[[3dgh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DGH FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nvk\|2nvk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nvk\|2nvk]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Trxr-1, GR, CG2151 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Trxr-1, GR, CG2151 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dgh RCSB], [http://www.ebi.ac.uk/pdbsum/3dgh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dgh RCSB], [http://www.ebi.ac.uk/pdbsum/3dgh PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TRXR1_DROME TRXR1_DROME]] Thioredoxin system is a major player in glutathione metabolism, due to the demonstrated absence of a glutathione reductase. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a glutathione reductase suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms.<ref>PMID:11158675</ref> <ref>PMID:11525742</ref> <ref>PMID:11796729</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 22:		Line 24:
	==See Also==		==See Also==
	*[[Thioredoxin Reductase\|Thioredoxin Reductase]]		*[[Thioredoxin Reductase\|Thioredoxin Reductase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Thioredoxin-disulfide reductase]]		[[Category: Thioredoxin-disulfide reductase]]
-	[[Category: Eckenroth, B E.]]	+	[[Category: Eckenroth, B E]]
-	[[Category: Everse, S J.]]	+	[[Category: Everse, S J]]
-	[[Category: Hondal, R J.]]	+	[[Category: Hondal, R J]]
	[[Category: Alternative initiation]]		[[Category: Alternative initiation]]
	[[Category: Fad]]		[[Category: Fad]]

OCA at 12:29, 29 September 2014

2014-09-29T12:29:55Z

←Older revision		Revision as of 12:29, 29 September 2014
Line 1:		Line 1:
-	~~[[Image:3dgh.png\|left\|200px]]~~	+	==Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation==
-		+	<StructureSection load='3dgh' size='340' side='right' caption='[[3dgh]], [[Resolution\|resolution]] 1.75Å' scene=''>
-	~~{{STRUCTURE_3dgh\| PDB=3dgh \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3dgh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DGH FirstGlance]. <br>
-	===Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nvk\|2nvk]]</td></tr>
-		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Trxr-1, GR, CG2151 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>
-	[[3dgh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA].	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dgh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dgh RCSB], [http://www.ebi.ac.uk/pdbsum/3dgh PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dg/3dgh_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Thioredoxin Reductase\|Thioredoxin Reductase]]		*[[Thioredoxin Reductase\|Thioredoxin Reductase]]
		+	__TOC__
		+	</StructureSection>
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Thioredoxin-disulfide reductase]]		[[Category: Thioredoxin-disulfide reductase]]

OCA at 05:57, 20 October 2012

2012-10-20T05:57:35Z

←Older revision		Revision as of 05:57, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[3dgh]] is a 2 chain structure ~~of [[Thioredoxin Reductase]]~~ with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA].	+	[[3dgh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA].

	==See Also==		==See Also==

OCA: Protected "3dgh" [edit=sysop:move=sysop]

2012-07-25T11:39:05Z

Protected "3dgh" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:39, 25 July 2012

OCA at 11:39, 25 July 2012

2012-07-25T11:39:03Z

←Older revision		Revision as of 11:39, 25 July 2012
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-	~~{{Seed}}~~	+	[[Image:3dgh.png\|left\|200px]]
-	[[Image:3dgh.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3dgh", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3dgh\| PDB=3dgh \| SCENE= }}		{{STRUCTURE_3dgh\| PDB=3dgh \| SCENE= }}

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	==About this Structure==		==About this Structure==
-	~~3DGH~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA].	+	[[3dgh]] is a 2 chain structure of [[Thioredoxin Reductase]] with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA].
		+
		+	==See Also==
		+	*[[Thioredoxin Reductase\|Thioredoxin Reductase]]
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Thioredoxin-disulfide reductase]]		[[Category: Thioredoxin-disulfide reductase]]
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	[[Category: Hondal, R J.]]		[[Category: Hondal, R J.]]
	[[Category: Alternative initiation]]		[[Category: Alternative initiation]]
-	[[Category: Alternative splicing]]
-	[[Category: Cytoplasm]]
	[[Category: Fad]]		[[Category: Fad]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]
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	[[Category: Rossmann]]		[[Category: Rossmann]]
	[[Category: Transit peptide]]		[[Category: Transit peptide]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 17 11:21:26 2009''

OCA at 08:21, 17 June 2009

2009-06-17T08:21:29Z

←Older revision		Revision as of 08:21, 17 June 2009
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3dgh.jpg\|left\|200px]]

-	The ~~entry 3dgh~~ is ~~ON HOLD~~ ~~until Jul 04 2010~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3dgh", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3dgh\| PDB=3dgh \| SCENE= }}

-	~~Authors: Eckenroth~~, ~~B.E., Hondal, R.J., Everse, S.J.~~	+	===Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation===

-	Description: Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 17:54:36 2009''	+	==About this Structure==
		+	3DGH is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DGH OCA].
		+	[[Category: Drosophila melanogaster]]
		+	[[Category: Thioredoxin-disulfide reductase]]
		+	[[Category: Eckenroth, B E.]]
		+	[[Category: Everse, S J.]]
		+	[[Category: Hondal, R J.]]
		+	[[Category: Alternative initiation]]
		+	[[Category: Alternative splicing]]
		+	[[Category: Cytoplasm]]
		+	[[Category: Fad]]
		+	[[Category: Flavoprotein]]
		+	[[Category: Mitochondrion]]
		+	[[Category: Nadp]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Redox-active center]]
		+	[[Category: Rossmann]]
		+	[[Category: Transit peptide]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 17 11:21:26 2009''

OCA at 14:54, 10 June 2009

2009-06-10T14:54:37Z

←Older revision		Revision as of 14:54, 10 June 2009
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3dgh is ON HOLD until ~~Paper Publication~~	+	The entry 3dgh is ON HOLD until Jul 04 2010

	Authors: Eckenroth, B.E., Hondal, R.J., Everse, S.J.		Authors: Eckenroth, B.E., Hondal, R.J., Everse, S.J.
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	Description: Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation		Description: Crystal Structure of Drosophila Thioredoxin Reductase, C-terminal 8-residue truncation

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Dec 31 09~~:41:~~28 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 17:54:36 2009''