3fc4 - Revision history

OCA at 15:28, 1 November 2023

2023-11-01T15:28:41Z

←Older revision		Revision as of 15:28, 1 November 2023
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	<StructureSection load='3fc4' size='340' side='right'caption='[[3fc4]], [[Resolution\|resolution]] 1.79Å' scene=''>		<StructureSection load='3fc4' size='340' side='right'caption='[[3fc4]], [[Resolution\|resolution]] 1.79Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fc4]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Desulfovibrio_gigas Desulfovibrio~~ gigas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FC4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3FC4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fc4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Megalodesulfovibrio_gigas Megalodesulfovibrio gigas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FC4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FC4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.79Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1sij\|1sij]], [[1zcs\|1zcs]], [[3fah\|3fah]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fc4 OCA], [https://pdbe.org/3fc4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fc4 RCSB], [https://www.ebi.ac.uk/pdbsum/3fc4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fc4 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3fc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fc4 OCA], [~~http~~://pdbe.org/3fc4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3fc4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3fc4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3fc4 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/MOP_MEGGA MOP_MEGGA]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Desulfovibrio gigas]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Romao, M J~~]]	+	[[Category: Megalodesulfovibrio gigas]]
-	[[Category: ~~Santos-Silva, T~~]]	+	[[Category: Romao MJ]]
-	[[Category: ~~2fe~~-~~2]]~~	+	[[Category: Santos-Silva T]]
-	~~[[Category: Fad]]~~	+
-	~~[[Category: Flavoprotein]]~~	+
-	~~[[Category: Iron]]~~	+
-	~~[[Category: Iron-sulfur]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Mo-ethylene glycol adduct]]~~	+
-	~~[[Category: Molybdenum]]~~	+
-	~~[[Category: Nad]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 10:29, 9 September 2020

2020-09-09T10:29:24Z

←Older revision		Revision as of 10:29, 9 September 2020
Line 1:		Line 1:

	==Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas==		==Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas==
-	<StructureSection load='3fc4' size='340' side='right' caption='[[3fc4]], [[Resolution\|resolution]] 1.79Å' scene=''>	+	<StructureSection load='3fc4' size='340' side='right'caption='[[3fc4]], [[Resolution\|resolution]] 1.79Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fc4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FC4 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3FC4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fc4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FC4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3FC4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1sij\|1sij]], [[1zcs\|1zcs]], [[3fah\|3fah]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1sij\|1sij]], [[1zcs\|1zcs]], [[3fah\|3fah]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3fc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fc4 OCA], [http://pdbe.org/3fc4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fc4 RCSB], [http://www.ebi.ac.uk/pdbsum/3fc4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fc4 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3fc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fc4 OCA], [http://pdbe.org/3fc4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fc4 RCSB], [http://www.ebi.ac.uk/pdbsum/3fc4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fc4 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Desulfovibrio gigas]]		[[Category: Desulfovibrio gigas]]
		+	[[Category: Large Structures]]
	[[Category: Romao, M J]]		[[Category: Romao, M J]]
	[[Category: Santos-Silva, T]]		[[Category: Santos-Silva, T]]

OCA at 07:39, 5 December 2018

2018-12-05T07:39:54Z

←Older revision		Revision as of 07:39, 5 December 2018
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/3fc4_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/3fc4_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 35:
	[[Category: Romao, M J]]		[[Category: Romao, M J]]
	[[Category: Santos-Silva, T]]		[[Category: Santos-Silva, T]]
		+	[[Category: 2fe-2]]
	[[Category: Fad]]		[[Category: Fad]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]

OCA at 11:51, 11 August 2016

2016-08-11T11:51:06Z

←Older revision		Revision as of 11:51, 11 August 2016
Line 1:		Line 1:
		+
	==Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas==		==Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas==
	<StructureSection load='3fc4' size='340' side='right' caption='[[3fc4]], [[Resolution\|resolution]] 1.79Å' scene=''>		<StructureSection load='3fc4' size='340' side='right' caption='[[3fc4]], [[Resolution\|resolution]] 1.79Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1sij\|1sij]], [[1zcs\|1zcs]], [[3fah\|3fah]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1sij\|1sij]], [[1zcs\|1zcs]], [[3fah\|3fah]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fc4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fc4 RCSB], [http://www.ebi.ac.uk/pdbsum/3fc4 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fc4 OCA], [http://pdbe.org/3fc4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fc4 RCSB], [http://www.ebi.ac.uk/pdbsum/3fc4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fc4 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fc4 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3fc4" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:55, 26 November 2014

2014-11-26T08:55:38Z

←Older revision		Revision as of 08:55, 26 November 2014
Line 1:		Line 1:
-	[[~~Image:~~3fc4.~~png~~\|~~left~~\|200px]]	+	==Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas==
		+	<StructureSection load='3fc4' size='340' side='right' caption='[[3fc4]], [[Resolution\|resolution]] 1.79Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3fc4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FC4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FC4 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1sij\|1sij]], [[1zcs\|1zcs]], [[3fah\|3fah]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fc4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fc4 RCSB], [http://www.ebi.ac.uk/pdbsum/3fc4 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/3fc4_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Aldehyde oxidoreductase from Desulfovibrio gigas (DgAOR) is a member of the xanthine oxidase (XO) family of mononuclear Mo-enzymes that catalyzes the oxidation of aldehydes to carboxylic acids. The molybdenum site in the enzymes of the XO family shows a distorted square pyramidal geometry in which two ligands, a hydroxyl/water molecule (the catalytic labile site) and a sulfido ligand, have been shown to be essential for catalysis. We report here steady-state kinetic studies of DgAOR with the inhibitors cyanide, ethylene glycol, glycerol, and arsenite, together with crystallographic and EPR studies of the enzyme after reaction with the two alcohols. In contrast to what has been observed in other members of the XO family, cyanide, ethylene glycol, and glycerol are reversible inhibitors of DgAOR. Kinetic data with both cyanide and samples prepared from single crystals confirm that DgAOR does not need a sulfido ligand for catalysis and confirm the absence of this ligand in the coordination sphere of the molybdenum atom in the active enzyme. Addition of ethylene glycol and glycerol to dithionite-reduced DgAOR yields rhombic Mo(V) EPR signals, suggesting that the nearly square pyramidal coordination of the active enzyme is distorted upon alcohol inhibition. This is in agreement with the X-ray structure of the ethylene glycol and glycerol-inhibited enzyme, where the catalytically labile OH/OH(2) ligand is lost and both alcohols coordinate the Mo site in a eta(2) fashion. The two adducts present a direct interaction between the molybdenum and one of the carbon atoms of the alcohol moiety, which constitutes the first structural evidence for such a bond in a biological system.

-	~~{{STRUCTURE_3fc4\| PDB=3fc4 \| SCENE= }}~~	+	Kinetic, structural, and EPR studies reveal that aldehyde oxidoreductase from Desulfovibrio gigas does not need a sulfido ligand for catalysis and give evidence for a direct Mo-C interaction in a biological system.,Santos-Silva T, Ferroni F, Thapper A, Marangon J, Gonzalez PJ, Rizzi AC, Moura I, Moura JJ, Romao MJ, Brondino CD J Am Chem Soc. 2009 Jun 17;131(23):7990-8. PMID:19459677<ref>PMID:19459677</ref>

-	~~===Ethylene glycol inhibited form~~ of ~~Aldehyde oxidoreductase from Desulfovibrio gigas===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19459677}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3fc4]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3FC4 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019459677<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Desulfovibrio gigas]]		[[Category: Desulfovibrio gigas]]
-	[[Category: Romao, M J.]]	+	[[Category: Romao, M J]]
-	[[Category: Santos-Silva, T.]]	+	[[Category: Santos-Silva, T]]
	[[Category: Fad]]		[[Category: Fad]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]

OCA: Protected "3fc4" [edit=sysop:move=sysop]

2013-02-13T11:21:38Z

Protected "3fc4" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:21, 13 February 2013

OCA at 11:21, 13 February 2013

2013-02-13T11:21:33Z

←Older revision		Revision as of 11:21, 13 February 2013
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3fc4.png\|left\|200px]]
-	[[Image:3fc4.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3fc4", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3fc4\| PDB=3fc4 \| SCENE= }}		{{STRUCTURE_3fc4\| PDB=3fc4 \| SCENE= }}

	===Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas===		===Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19459677}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19459677 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19459677}}		{{ABSTRACT_PUBMED_19459677}}

	==About this Structure==		==About this Structure==
-	~~3FC4~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FC4 OCA].	+	[[3fc4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FC4 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19459677~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019459677</ref><references group="xtra"/>
	[[Category: Desulfovibrio gigas]]		[[Category: Desulfovibrio gigas]]
	[[Category: Romao, M J.]]		[[Category: Romao, M J.]]
	[[Category: Santos-Silva, T.]]		[[Category: Santos-Silva, T.]]
-	[[Category: 2fe-2]]
	[[Category: Fad]]		[[Category: Fad]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]
Line 37:		Line 24:
	[[Category: Nad]]		[[Category: Nad]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 14:02:48 2009''

OCA at 12:02, 7 October 2009

2009-10-07T12:02:50Z

←Older revision		Revision as of 12:02, 7 October 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3fc4.jpg\|left\|200px]]

-	The ~~entry 3fc4~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3fc4", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3fc4\| PDB=3fc4 \| SCENE= }}

-	~~Authors: Santos-Silva, T., Romao, M.J.~~	+	===Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas===

-	Description: Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 10 17~~:55:42 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19459677}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19459677 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19459677}}
		+
		+	==About this Structure==
		+	3FC4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FC4 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19459677</ref><references group="xtra"/>
		+	[[Category: Desulfovibrio gigas]]
		+	[[Category: Romao, M J.]]
		+	[[Category: Santos-Silva, T.]]
		+	[[Category: 2fe-2]]
		+	[[Category: Fad]]
		+	[[Category: Flavoprotein]]
		+	[[Category: Iron]]
		+	[[Category: Iron-sulfur]]
		+	[[Category: Metal-binding]]
		+	[[Category: Mo-ethylene glycol adduct]]
		+	[[Category: Molybdenum]]
		+	[[Category: Nad]]
		+	[[Category: Oxidoreductase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 14:02:48 2009''

OCA at 14:55, 10 June 2009

2009-06-10T14:55:43Z

←Older revision		Revision as of 14:55, 10 June 2009
Line 3:		Line 3:
	The entry 3fc4 is ON HOLD until Paper Publication		The entry 3fc4 is ON HOLD until Paper Publication

-	Authors: Santos-Silva, T~~., Ferroni, F., Thapper, A., Marangon, J., Gonzalez, P.J., Rizzi, A.C., Moura, I., Moura, J.J.G~~., Romao, M.J~~., Brondino, C.D~~.	+	Authors: Santos-Silva, T., Romao, M.J.

	Description: Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas		Description: Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Dec 31 09~~:46:~~48 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 17:55:42 2009''

OCA at 07:46, 31 December 2008

2008-12-31T07:46:49Z

←Older revision		Revision as of 07:46, 31 December 2008
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3fc4 is ON HOLD	+	The entry 3fc4 is ON HOLD until Paper Publication

	Authors: Santos-Silva, T., Ferroni, F., Thapper, A., Marangon, J., Gonzalez, P.J., Rizzi, A.C., Moura, I., Moura, J.J.G., Romao, M.J., Brondino, C.D.		Authors: Santos-Silva, T., Ferroni, F., Thapper, A., Marangon, J., Gonzalez, P.J., Rizzi, A.C., Moura, I., Moura, J.J.G., Romao, M.J., Brondino, C.D.
Line 7:		Line 7:
	Description: Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas		Description: Ethylene glycol inhibited form of Aldehyde oxidoreductase from Desulfovibrio gigas

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec ~~10 14~~:41:06 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 09:46:48 2008''