3fte - Revision history

OCA at 13:09, 30 August 2023

2023-08-30T13:09:01Z

←Older revision		Revision as of 13:09, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='3fte' size='340' side='right'caption='[[3fte]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3fte' size='340' side='right'caption='[[3fte]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fte]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Aquae Aquae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FTE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fte]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FTE FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1qyr\|1qyr]], [[1zq9\|1zq9]], [[1g38\|1g38]], [[3ftc\|3ftc]], [[3ftd\|3ftd]], [[3ftf\|3ftf]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">aq_1816, ksgA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=224324 AQUAE])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fte OCA], [https://pdbe.org/3fte PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fte RCSB], [https://www.ebi.ac.uk/pdbsum/3fte PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fte ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fte OCA], [https://pdbe.org/3fte PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fte RCSB], [https://www.ebi.ac.uk/pdbsum/3fte PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fte ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RSMA_AQUAE RSMA_AQUAE]] Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity).	+	[https://www.uniprot.org/uniprot/RSMA_AQUAE RSMA_AQUAE] Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Aquae~~]]	+	[[Category: Aquifex aeolicus VF5]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ji, X]]	+	[[Category: Ji X]]
-	[[Category: Tu, C]]	+	[[Category: Tu C]]
-	~~[[Category: Antibiotic resistance]]~~	+
-	~~[[Category: Ksga]]~~	+
-	~~[[Category: Methyltransferase]]~~	+
-	~~[[Category: Mtase]]~~	+
-	~~[[Category: Rna]]~~	+
-	~~[[Category: Rna methyltransferase]]~~	+
-	~~[[Category: Rna-binding]]~~	+
-	~~[[Category: Rossmann-like fold]]~~	+
-	~~[[Category: Rrna processing]]~~	+
-	~~[[Category: S-adenosyl-l-methionine]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Transferase-rna complex~~]]	+

OCA at 08:10, 2 March 2022

2022-03-02T08:10:22Z

←Older revision		Revision as of 08:10, 2 March 2022
Line 1:		Line 1:

	==Crystal structure of A. aeolicus KsgA in complex with RNA==		==Crystal structure of A. aeolicus KsgA in complex with RNA==
-	<StructureSection load='3fte' size='340' side='right' caption='[[3fte]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='3fte' size='340' side='right'caption='[[3fte]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fte]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3FTE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fte]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FTE FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qyr\|1qyr]], [[1zq9\|1zq9]], [[1g38\|1g38]], [[3ftc\|3ftc]], [[3ftd\|3ftd]], [[3ftf\|3ftf]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1qyr\|1qyr]], [[1zq9\|1zq9]], [[1g38\|1g38]], [[3ftc\|3ftc]], [[3ftd\|3ftd]], [[3ftf\|3ftf]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aq_1816, ksgA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aq_1816, ksgA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3fte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fte OCA], [~~http~~://pdbe.org/3fte PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3fte RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3fte PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3fte ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fte OCA], [https://pdbe.org/3fte PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fte RCSB], [https://www.ebi.ac.uk/pdbsum/3fte PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fte ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RSMA_AQUAE RSMA_AQUAE]] Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity).	+	[[https://www.uniprot.org/uniprot/RSMA_AQUAE RSMA_AQUAE]] Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Adenosine dimethyltransferase\|Adenosine dimethyltransferase]]	+	*[[Adenosine dimethyltransferase 3D structures\|Adenosine dimethyltransferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Aquae]]		[[Category: Aquae]]
		+	[[Category: Large Structures]]
	[[Category: Ji, X]]		[[Category: Ji, X]]
	[[Category: Tu, C]]		[[Category: Tu, C]]

OCA at 07:39, 5 December 2018

2018-12-05T07:39:57Z

←Older revision		Revision as of 07:39, 5 December 2018
Line 1:		Line 1:
		+
	==Crystal structure of A. aeolicus KsgA in complex with RNA==		==Crystal structure of A. aeolicus KsgA in complex with RNA==
	<StructureSection load='3fte' size='340' side='right' caption='[[3fte]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3fte' size='340' side='right' caption='[[3fte]], [[Resolution\|resolution]] 3.00Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qyr\|1qyr]], [[1zq9\|1zq9]], [[1g38\|1g38]], [[3ftc\|3ftc]], [[3ftd\|3ftd]], [[3ftf\|3ftf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qyr\|1qyr]], [[1zq9\|1zq9]], [[1g38\|1g38]], [[3ftc\|3ftc]], [[3ftd\|3ftd]], [[3ftf\|3ftf]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aq_1816, ksgA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aq_1816, ksgA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fte OCA], [http://pdbe.org/3fte PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fte RCSB], [http://www.ebi.ac.uk/pdbsum/3fte PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fte OCA], [http://pdbe.org/3fte PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fte RCSB], [http://www.ebi.ac.uk/pdbsum/3fte PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fte ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ft/3fte_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ft/3fte_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 22:56, 7 February 2016

2016-02-07T22:56:18Z

←Older revision		Revision as of 22:56, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3fte' size='340' side='right' caption='[[3fte]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3fte' size='340' side='right' caption='[[3fte]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fte]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Aquifex_aeolicus Aquifex aeolicus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FTE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fte]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FTE FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qyr\|1qyr]], [[1zq9\|1zq9]], [[1g38\|1g38]], [[3ftc\|3ftc]], [[3ftd\|3ftd]], [[3ftf\|3ftf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qyr\|1qyr]], [[1zq9\|1zq9]], [[1g38\|1g38]], [[3ftc\|3ftc]], [[3ftd\|3ftd]], [[3ftf\|3ftf]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aq_1816, ksgA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~63363 Aquifex aeolicus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aq_1816, ksgA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fte OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fte RCSB], [http://www.ebi.ac.uk/pdbsum/3fte PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fte OCA], [http://pdbe.org/3fte PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fte RCSB], [http://www.ebi.ac.uk/pdbsum/3fte PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~KSGA_AQUAE KSGA_AQUAE~~]] Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.~~[HAMAP-Rule:MF_00607]~~	+	[[http://www.uniprot.org/uniprot/RSMA_AQUAE RSMA_AQUAE]] Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fte ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3fte" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Aquifex aeolicus~~]]	+	[[Category: Aquae]]
	[[Category: Ji, X]]		[[Category: Ji, X]]
	[[Category: Tu, C]]		[[Category: Tu, C]]

OCA at 18:46, 24 December 2014

2014-12-24T18:46:32Z

←Older revision		Revision as of 18:46, 24 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fte OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fte RCSB], [http://www.ebi.ac.uk/pdbsum/3fte PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fte OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fte RCSB], [http://www.ebi.ac.uk/pdbsum/3fte PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/KSGA_AQUAE KSGA_AQUAE]] Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.[HAMAP-Rule:MF_00607]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:27, 3 December 2014

2014-12-03T10:27:14Z

←Older revision		Revision as of 10:27, 3 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3fte.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of A. aeolicus KsgA in complex with RNA==
		+	<StructureSection load='3fte' size='340' side='right' caption='[[3fte]], [[Resolution\|resolution]] 3.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3fte]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FTE FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qyr\|1qyr]], [[1zq9\|1zq9]], [[1g38\|1g38]], [[3ftc\|3ftc]], [[3ftd\|3ftd]], [[3ftf\|3ftf]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aq_1816, ksgA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 Aquifex aeolicus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fte OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fte RCSB], [http://www.ebi.ac.uk/pdbsum/3fte PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ft/3fte_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Among methyltransferases, KsgA and the reaction it catalyzes are conserved throughout evolution. However, the specifics of substrate recognition by the enzyme remain unknown. Here we report structures of Aquifex aeolicus KsgA, in its ligand-free form, in complex with RNA, and in complex with both RNA and S-adenosylhomocysteine (SAH, reaction product of cofactor S-adenosylmethionine), revealing critical structural information on KsgA-RNA and KsgA-SAH interactions. Moreover, the structures show how conformational changes that occur upon RNA binding create the cofactor-binding site. There are nine conserved functional motifs (motifs I-VIII and X) in KsgA. Prior to RNA binding, motifs I and VIII are flexible, each exhibiting two distinct conformations. Upon RNA binding, the two motifs become stabilized in one of these conformations, which is compatible with the binding of SAH. Motif X, which is also stabilized upon RNA binding, is directly involved in the binding of SAH.

-	~~{{STRUCTURE_3fte\| PDB=3fte \| SCENE= }}~~	+	Structural basis for binding of RNA and cofactor by a KsgA methyltransferase.,Tu C, Tropea JE, Austin BP, Court DL, Waugh DS, Ji X Structure. 2009 Mar 11;17(3):374-85. PMID:19278652<ref>PMID:19278652</ref>

-	~~===Crystal structure~~ of A. ~~aeolicus KsgA in complex with RNA===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_19278652}}~~	+	==See Also==
-		+	*[[Adenosine dimethyltransferase\|Adenosine dimethyltransferase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~3fte~~]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTE OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:019278652<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Aquifex aeolicus]]		[[Category: Aquifex aeolicus]]
-	[[Category: Ji, X.]]	+	[[Category: Ji, X]]
-	[[Category: Tu, C.]]	+	[[Category: Tu, C]]
	[[Category: Antibiotic resistance]]		[[Category: Antibiotic resistance]]
	[[Category: Ksga]]		[[Category: Ksga]]

OCA: Protected "3fte" [edit=sysop:move=sysop]

2013-02-20T14:47:56Z

Protected "3fte" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:47, 20 February 2013

OCA at 14:47, 20 February 2013

2013-02-20T14:47:52Z

←Older revision		Revision as of 14:47, 20 February 2013
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-	~~{{Seed}}~~	+	[[Image:3fte.png\|left\|200px]]
-	[[Image:3fte.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3fte", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3fte\| PDB=3fte \| SCENE= }}		{{STRUCTURE_3fte\| PDB=3fte \| SCENE= }}

	===Crystal structure of A. aeolicus KsgA in complex with RNA===		===Crystal structure of A. aeolicus KsgA in complex with RNA===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19278652}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19278652 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_19278652}}		{{ABSTRACT_PUBMED_19278652}}

	==About this Structure==		==About this Structure==
-	~~3FTE~~ is a 3 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/~~Aquifex_aeolicus_vf5~~ Aquifex aeolicus ~~vf5~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTE OCA].	+	[[3fte]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTE OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19278652~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019278652</ref><references group="xtra"/>
-	[[Category: Aquifex aeolicus ~~vf5~~]]	+	[[Category: Aquifex aeolicus]]
	[[Category: Ji, X.]]		[[Category: Ji, X.]]
	[[Category: Tu, C.]]		[[Category: Tu, C.]]
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	[[Category: S-adenosyl-l-methionine]]		[[Category: S-adenosyl-l-methionine]]
	[[Category: Transferase]]		[[Category: Transferase]]
-	[[Category: Transferase/rna complex]]	+	[[Category: Transferase-rna complex]]
-		+
-	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:34:06 2009''~~	+

OCA at 10:34, 25 March 2009

2009-03-25T10:34:10Z

←Older revision		Revision as of 10:34, 25 March 2009
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3fte.jpg\|left\|200px]]

-	The ~~entry 3fte~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3fte", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3fte\| PDB=3fte \| SCENE= }}

-	~~Authors: Tu, C., Ji, X~~.	+	===Crystal structure of A. aeolicus KsgA in complex with RNA===

-	Description: Crystal structure of A. aeolicus KsgA in complex with RNA

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jan 21 10~~:40:03 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19278652}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19278652 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19278652}}
		+
		+	==About this Structure==
		+	3FTE is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Aquifex_aeolicus_vf5 Aquifex aeolicus vf5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTE OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19278652</ref><references group="xtra"/>
		+	[[Category: Aquifex aeolicus vf5]]
		+	[[Category: Ji, X.]]
		+	[[Category: Tu, C.]]
		+	[[Category: Antibiotic resistance]]
		+	[[Category: Ksga]]
		+	[[Category: Methyltransferase]]
		+	[[Category: Mtase]]
		+	[[Category: Rna]]
		+	[[Category: Rna methyltransferase]]
		+	[[Category: Rna-binding]]
		+	[[Category: Rossmann-like fold]]
		+	[[Category: Rrna processing]]
		+	[[Category: S-adenosyl-l-methionine]]
		+	[[Category: Transferase]]
		+	[[Category: Transferase/rna complex]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:34:06 2009''

OCA: New page: '''Unreleased structure''' The entry 3fte is ON HOLD until Paper Publication Authors: Tu, C., Ji, X. Description: Crystal structure of A. aeolicus KsgA in complex with RNA ''Page seed...

2009-01-21T08:40:04Z

New page: '''Unreleased structure''' The entry 3fte is ON HOLD until Paper Publication Authors: Tu, C., Ji, X. Description: Crystal structure of A. aeolicus KsgA in complex with RNA ''Page seed...

New page

'''Unreleased structure'''

The entry 3fte is ON HOLD until Paper Publication

Authors: Tu, C., Ji, X.

Description: Crystal structure of A. aeolicus KsgA in complex with RNA

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 21 10:40:03 2009''