3fvf - Revision history

OCA at 19:58, 20 October 2021

2021-10-20T19:58:42Z

←Older revision		Revision as of 19:58, 20 October 2021
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	==The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution==		==The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution==
-	<StructureSection load='3fvf' size='340' side='right' caption='[[3fvf]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='3fvf' size='340' side='right'caption='[[3fvf]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fvf]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3FVF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fvf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FVF FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1JZ:1-[4-(HYDROXYMETHYL)PHENYL]GUANIDINE'>1JZ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1JZ:1-[4-(HYDROXYMETHYL)PHENYL]GUANIDINE'>1JZ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3e1x\|3e1x]], [[3e0n\|3e0n]], [[3e0p\|3e0p]], [[3e16\|3e16]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3e1x\|3e1x]], [[3e0n\|3e0n]], [[3e0p\|3e0p]], [[3e16\|3e16]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PRSS8 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PRSS8 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3fvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvf OCA], [~~http~~://pdbe.org/3fvf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3fvf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3fvf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3fvf ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvf OCA], [https://pdbe.org/3fvf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fvf RCSB], [https://www.ebi.ac.uk/pdbsum/3fvf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fvf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PRSS8_HUMAN PRSS8_HUMAN]] Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).<ref>PMID:15246975</ref> <ref>PMID:15474520</ref>	+	[[https://www.uniprot.org/uniprot/PRSS8_HUMAN PRSS8_HUMAN]] Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).<ref>PMID:15246975</ref> <ref>PMID:15474520</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/3fvf_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/3fvf_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Harris, J L]]		[[Category: Harris, J L]]
	[[Category: Hornsby, M]]		[[Category: Hornsby, M]]

OCA at 06:50, 1 November 2017

2017-11-01T06:50:46Z

←Older revision		Revision as of 06:50, 1 November 2017
Line 1:		Line 1:
		+
	==The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution==		==The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution==
	<StructureSection load='3fvf' size='340' side='right' caption='[[3fvf]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3fvf' size='340' side='right' caption='[[3fvf]], [[Resolution\|resolution]] 1.60Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3e1x\|3e1x]], [[3e0n\|3e0n]], [[3e0p\|3e0p]], [[3e16\|3e16]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3e1x\|3e1x]], [[3e0n\|3e0n]], [[3e0p\|3e0p]], [[3e16\|3e16]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PRSS8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PRSS8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvf OCA], [http://pdbe.org/3fvf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fvf RCSB], [http://www.ebi.ac.uk/pdbsum/3fvf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvf OCA], [http://pdbe.org/3fvf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fvf RCSB], [http://www.ebi.ac.uk/pdbsum/3fvf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fvf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 06:12, 9 February 2016

2016-02-09T06:12:21Z

←Older revision		Revision as of 06:12, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3fvf' size='340' side='right' caption='[[3fvf]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3fvf' size='340' side='right' caption='[[3fvf]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fvf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FVF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fvf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FVF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1JZ:1-[4-(HYDROXYMETHYL)PHENYL]GUANIDINE'>1JZ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1JZ:1-[4-(HYDROXYMETHYL)PHENYL]GUANIDINE'>1JZ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3e1x\|3e1x]], [[3e0n\|3e0n]], [[3e0p\|3e0p]], [[3e16\|3e16]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3e1x\|3e1x]], [[3e0n\|3e0n]], [[3e0p\|3e0p]], [[3e16\|3e16]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PRSS8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PRSS8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fvf RCSB], [http://www.ebi.ac.uk/pdbsum/3fvf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvf OCA], [http://pdbe.org/3fvf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fvf RCSB], [http://www.ebi.ac.uk/pdbsum/3fvf PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fvf ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3fvf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Harris, J L]]		[[Category: Harris, J L]]
	[[Category: Hornsby, M]]		[[Category: Hornsby, M]]

OCA at 04:56, 25 December 2014

2014-12-25T04:56:48Z

←Older revision		Revision as of 04:56, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fvf RCSB], [http://www.ebi.ac.uk/pdbsum/3fvf PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fvf RCSB], [http://www.ebi.ac.uk/pdbsum/3fvf PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PRSS8_HUMAN PRSS8_HUMAN]] Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).<ref>PMID:15246975</ref> <ref>PMID:15474520</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:28, 3 December 2014

2014-12-03T10:28:58Z

←Older revision		Revision as of 10:28, 3 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3fvf.~~png~~\|~~left~~\|200px]]	+	==The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution==
		+	<StructureSection load='3fvf' size='340' side='right' caption='[[3fvf]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3fvf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FVF FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1JZ:1-[4-(HYDROXYMETHYL)PHENYL]GUANIDINE'>1JZ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3e1x\|3e1x]], [[3e0n\|3e0n]], [[3e0p\|3e0p]], [[3e16\|3e16]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PRSS8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fvf RCSB], [http://www.ebi.ac.uk/pdbsum/3fvf PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/3fvf_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Prostasin or human channel-activating protease 1 has been reported to play a critical role in the regulation of extracellular sodium ion transport via its activation of the epithelial cell sodium channel. Here, the structure of the extracellular portion of the membrane associated serine protease has been solved to high resolution in complex with a nonselective d-FFR chloromethyl ketone inhibitor, in an apo form, in a form where the apo crystal has been soaked with the covalent inhibitor camostat and in complex with the protein inhibitor aprotinin. It was also crystallized in the presence of the divalent cation Ca(+2). Comparison of the structures with each other and with other members of the trypsin-like serine protease family reveals unique structural features of prostasin and a large degree of conformational variation within specificity determining loops. Of particular interest is the S1 subsite loop which opens and closes in response to basic residues or divalent ions, directly binding Ca(+2) cations. This induced fit active site provides a new possible mode of regulation of trypsin-like proteases adapted in particular to extracellular regions with variable ionic concentrations such as the outer membrane layer of the epithelial cell.

-	~~{{STRUCTURE_3fvf\| PDB=3fvf \| SCENE= }}~~	+	Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations.,Spraggon G, Hornsby M, Shipway A, Tully DC, Bursulaya B, Danahay H, Harris JL, Lesley SA Protein Sci. 2009 May;18(5):1081-94. PMID:19388054<ref>PMID:19388054</ref>

-	~~===The Crystal Structure~~ of ~~Prostasin Complexed with Camostat at 1~~.~~6 Angstroms Resolution===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19388054}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3fvf]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVF OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019388054<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Harris, J L.]]	+	[[Category: Harris, J L]]
-	[[Category: Hornsby, M.]]	+	[[Category: Hornsby, M]]
-	[[Category: Lesley, S A.]]	+	[[Category: Lesley, S A]]
-	[[Category: Shipway, A.]]	+	[[Category: Shipway, A]]
-	[[Category: Spraggon, G.]]	+	[[Category: Spraggon, G]]
	[[Category: Cell membrane]]		[[Category: Cell membrane]]
	[[Category: Channel activating protease]]		[[Category: Channel activating protease]]

OCA: Protected "3fvf" [edit=sysop:move=sysop]

2013-02-20T14:51:07Z

Protected "3fvf" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:51, 20 February 2013

OCA at 14:51, 20 February 2013

2013-02-20T14:51:04Z

←Older revision		Revision as of 14:51, 20 February 2013
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3fvf.png\|left\|200px]]
-	[[Image:3fvf.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3fvf", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3fvf\| PDB=3fvf \| SCENE= }}		{{STRUCTURE_3fvf\| PDB=3fvf \| SCENE= }}

	===The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution===		===The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19388054}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19388054 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19388054}}		{{ABSTRACT_PUBMED_19388054}}

	==About this Structure==		==About this Structure==
-	~~3FVF~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVF OCA].	+	[[3fvf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVF OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19388054~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019388054</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Harris, J L.]]		[[Category: Harris, J L.]]
Line 44:		Line 32:
	[[Category: Transmembrane]]		[[Category: Transmembrane]]
	[[Category: Zymogen]]		[[Category: Zymogen]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 10:24:22 2009''

OCA at 07:24, 6 May 2009

2009-05-06T07:24:23Z

←Older revision		Revision as of 07:24, 6 May 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3fvf.jpg\|left\|200px]]

-	The ~~entry 3fvf~~ is ~~ON HOLD until sometime in~~ the ~~future~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3fvf", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3fvf\| PDB=3fvf \| SCENE= }}

-	~~Authors: Spraggon, G., Hornsby, M., Shipway, A., Harris, J.L., Lesley, S.A~~.	+	===The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution===

-	Description: The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Feb 18 08~~:53:43 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19388054}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19388054 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19388054}}
		+
		+	==About this Structure==
		+	3FVF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVF OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19388054</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Harris, J L.]]
		+	[[Category: Hornsby, M.]]
		+	[[Category: Lesley, S A.]]
		+	[[Category: Shipway, A.]]
		+	[[Category: Spraggon, G.]]
		+	[[Category: Cell membrane]]
		+	[[Category: Channel activating protease]]
		+	[[Category: Enac]]
		+	[[Category: Glycoprotein]]
		+	[[Category: Hcap-1]]
		+	[[Category: Hydrolase]]
		+	[[Category: Inhibitor]]
		+	[[Category: Membrane]]
		+	[[Category: Prostasin]]
		+	[[Category: Protease]]
		+	[[Category: Secreted]]
		+	[[Category: Serine protease]]
		+	[[Category: Transmembrane]]
		+	[[Category: Zymogen]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 10:24:22 2009''

OCA at 06:53, 18 February 2009

2009-02-18T06:53:43Z

←Older revision		Revision as of 06:53, 18 February 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3fvf is ON HOLD	+	The entry 3fvf is ON HOLD until sometime in the future

	Authors: Spraggon, G., Hornsby, M., Shipway, A., Harris, J.L., Lesley, S.A.		Authors: Spraggon, G., Hornsby, M., Shipway, A., Harris, J.L., Lesley, S.A.
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	Description: The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution		Description: The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb ~~4 11~~:26:06 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:53:43 2009''

OCA at 09:26, 4 February 2009

2009-02-04T09:26:06Z

←Older revision		Revision as of 09:26, 4 February 2009
Line 3:		Line 3:
	The entry 3fvf is ON HOLD		The entry 3fvf is ON HOLD

-	Authors: Spraggon, G., Hornsby, M., Shipway, A~~., Tully, D.C., Bursulaya, B., Danahay, H~~., Harris, J.L., Lesley, S. A.	+	Authors: Spraggon, G., Hornsby, M., Shipway, A., Harris, J.L., Lesley, S.A.

	Description: The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution		Description: The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jan 21 10~~:40:48 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 11:26:06 2009''