3fwa - Revision history

OCA at 06:53, 6 September 2023

2023-09-06T06:53:07Z

←Older revision		Revision as of 06:53, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3fwa' size='340' side='right'caption='[[3fwa]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3fwa' size='340' side='right'caption='[[3fwa]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fwa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~California_poppy California poppy~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FWA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fwa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FWA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FAD:FLAVIN~~-~~ADENINE+DINUCLEOTIDE'>FAD</scene>~~, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=REN:(S)-RETICULINE'>REN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.496Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3d3d\|3d3d]], [[3d2h\|3d2h]], [[3d2j\|3d2j]], [[3fw7\|3fw7]], [[3fw8\|3fw8]], [[3fw9\|3fw9]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=REN:(S)-RETICULINE'>REN</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td><~~td class~~=~~"sblockDat">BBE1 ([https~~:~~//www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3467 California poppy])</td~~></tr>	+
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Reticuline_oxidase Reticuline oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.21.3.3 1.21.3.3]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [https://pdbe.org/3fwa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [https://www.ebi.ac.uk/pdbsum/3fwa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fwa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [https://pdbe.org/3fwa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [https://www.ebi.ac.uk/pdbsum/3fwa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fwa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RETO_ESCCA RETO_ESCCA]] Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.	+	[https://www.uniprot.org/uniprot/RETO_ESCCA RETO_ESCCA] Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 27:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~California poppy~~]]	+	[[Category: Eschscholzia californica]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Reticuline oxidase]]~~	+	[[Category: Gruber K]]
-	[[Category: Gruber, K]]	+	[[Category: Macheroux P]]
-	[[Category: Macheroux, P]]	+	[[Category: Winkler A]]
-	[[Category: Winkler, A]]	+
-	~~[[Category: Alakloid biosynthesis]]~~	+
-	~~[[Category: Alkaloid metabolism]]~~	+
-	~~[[Category: Bi-covalent flavinylation]]~~	+
-	~~[[Category: Cytoplasmic vesicle]]~~	+
-	~~[[Category: Fad]]~~	+
-	~~[[Category: Flavoprotein]]~~	+
-	~~[[Category: Glycoprotein]]~~	+
-	~~[[Category: N-glycosylation]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 19:59, 20 October 2021

2021-10-20T19:59:03Z

←Older revision		Revision as of 19:59, 20 October 2021
Line 1:		Line 1:

	==Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline==		==Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline==
-	<StructureSection load='3fwa' size='340' side='right' caption='[[3fwa]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='3fwa' size='340' side='right'caption='[[3fwa]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fwa]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/California_poppy California poppy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3FWA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fwa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/California_poppy California poppy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FWA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD~~</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN~~</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=REN:(S)-RETICULINE'>REN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=REN:(S)-RETICULINE'>REN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d3d\|3d3d]], [[3d2h\|3d2h]], [[3d2j\|3d2j]], [[3fw7\|3fw7]], [[3fw8\|3fw8]], [[3fw9\|3fw9]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3d3d\|3d3d]], [[3d2h\|3d2h]], [[3d2j\|3d2j]], [[3fw7\|3fw7]], [[3fw8\|3fw8]], [[3fw9\|3fw9]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BBE1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3467 California poppy])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BBE1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3467 California poppy])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Reticuline_oxidase Reticuline oxidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.21.3.3 1.21.3.3] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Reticuline_oxidase Reticuline oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.21.3.3 1.21.3.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [~~http~~://pdbe.org/3fwa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3fwa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3fwa ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [https://pdbe.org/3fwa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [https://www.ebi.ac.uk/pdbsum/3fwa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fwa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RETO_ESCCA RETO_ESCCA]] Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.	+	[[https://www.uniprot.org/uniprot/RETO_ESCCA RETO_ESCCA]] Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 22:		Line 22:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fwa ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fwa ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+
		+	==See Also==
		+	*[[Reticuline oxidase\|Reticuline oxidase]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: California poppy]]		[[Category: California poppy]]
		+	[[Category: Large Structures]]
	[[Category: Reticuline oxidase]]		[[Category: Reticuline oxidase]]
	[[Category: Gruber, K]]		[[Category: Gruber, K]]

OCA at 08:03, 5 December 2018

2018-12-05T08:03:43Z

←Older revision		Revision as of 08:03, 5 December 2018
Line 1:		Line 1:
		+
	==Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline==		==Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline==
	<StructureSection load='3fwa' size='340' side='right' caption='[[3fwa]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3fwa' size='340' side='right' caption='[[3fwa]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3fwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/California_poppy California poppy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FWA FirstGlance]. <br>		<table><tr><td colspan='2'>[[3fwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/California_poppy California poppy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FWA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=REN:(S)-RETICULINE'>REN~~</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=REN:(S)-RETICULINE'>REN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d3d\|3d3d]], [[3d2h\|3d2h]], [[3d2j\|3d2j]], [[3fw7\|3fw7]], [[3fw8\|3fw8]], [[3fw9\|3fw9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d3d\|3d3d]], [[3d2h\|3d2h]], [[3d2j\|3d2j]], [[3fw7\|3fw7]], [[3fw8\|3fw8]], [[3fw9\|3fw9]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BBE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3467 California poppy])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BBE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3467 California poppy])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Reticuline_oxidase Reticuline oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.21.3.3 1.21.3.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Reticuline_oxidase Reticuline oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.21.3.3 1.21.3.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [http://pdbe.org/3fwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [http://www.ebi.ac.uk/pdbsum/3fwa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [http://pdbe.org/3fwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [http://www.ebi.ac.uk/pdbsum/3fwa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fwa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/3fwa_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/3fwa_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 01:50, 9 February 2016

2016-02-09T01:50:46Z

←Older revision		Revision as of 01:50, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3fwa' size='340' side='right' caption='[[3fwa]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3fwa' size='340' side='right' caption='[[3fwa]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Eschscholzia_californica Eschscholzia californica~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FWA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/California_poppy California poppy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FWA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=REN:(S)-RETICULINE'>REN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=REN:(S)-RETICULINE'>REN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d3d\|3d3d]], [[3d2h\|3d2h]], [[3d2j\|3d2j]], [[3fw7\|3fw7]], [[3fw8\|3fw8]], [[3fw9\|3fw9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d3d\|3d3d]], [[3d2h\|3d2h]], [[3d2j\|3d2j]], [[3fw7\|3fw7]], [[3fw8\|3fw8]], [[3fw9\|3fw9]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BBE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3467 ~~Eschscholzia californica~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BBE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3467 California poppy])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Reticuline_oxidase Reticuline oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.21.3.3 1.21.3.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Reticuline_oxidase Reticuline oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.21.3.3 1.21.3.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [http://www.ebi.ac.uk/pdbsum/3fwa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [http://pdbe.org/3fwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [http://www.ebi.ac.uk/pdbsum/3fwa PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fwa ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Eschscholzia californica~~]]	+	[[Category: California poppy]]
	[[Category: Reticuline oxidase]]		[[Category: Reticuline oxidase]]
	[[Category: Gruber, K]]		[[Category: Gruber, K]]

OCA at 03:35, 25 December 2014

2014-12-25T03:35:55Z

←Older revision		Revision as of 03:35, 25 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [http://www.ebi.ac.uk/pdbsum/3fwa PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [http://www.ebi.ac.uk/pdbsum/3fwa PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RETO_ESCCA RETO_ESCCA]] Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:24, 3 December 2014

2014-12-03T10:24:32Z

←Older revision		Revision as of 10:24, 3 December 2014
Line 1:		Line 1:
-	~~[[Image:3fwa.png\|left\|200px]]~~	+	==Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline==
-		+	<StructureSection load='3fwa' size='340' side='right' caption='[[3fwa]], [[Resolution\|resolution]] 1.50Å' scene=''>
-	~~{{STRUCTURE_3fwa\| PDB=3fwa \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3fwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FWA FirstGlance]. <br>
-	===Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline===	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=REN:(S)-RETICULINE'>REN</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d3d\|3d3d]], [[3d2h\|3d2h]], [[3d2j\|3d2j]], [[3fw7\|3fw7]], [[3fw8\|3fw8]], [[3fw9\|3fw9]]</td></tr>
-		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BBE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3467 Eschscholzia californica])</td></tr>
-	==~~About this Structure~~==	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Reticuline_oxidase Reticuline oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.21.3.3 1.21.3.3] </span></td></tr>
-	[[3fwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA].	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fwa RCSB], [http://www.ebi.ac.uk/pdbsum/3fwa PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/3fwa_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	__TOC__
		+	</StructureSection>
	[[Category: Eschscholzia californica]]		[[Category: Eschscholzia californica]]
	[[Category: Reticuline oxidase]]		[[Category: Reticuline oxidase]]
-	[[Category: Gruber, K.]]	+	[[Category: Gruber, K]]
-	[[Category: Macheroux, P.]]	+	[[Category: Macheroux, P]]
-	[[Category: Winkler, A.]]	+	[[Category: Winkler, A]]
	[[Category: Alakloid biosynthesis]]		[[Category: Alakloid biosynthesis]]
	[[Category: Alkaloid metabolism]]		[[Category: Alkaloid metabolism]]

OCA: Protected "3fwa" [edit=sysop:move=sysop]

2013-02-20T14:43:04Z

Protected "3fwa" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:43, 20 February 2013

OCA at 14:42, 20 February 2013

2013-02-20T14:42:59Z

←Older revision		Revision as of 14:42, 20 February 2013
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3fwa.png\|left\|200px]]
-	[[Image:3fwa.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3fwa", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3fwa\| PDB=3fwa \| SCENE= }}		{{STRUCTURE_3fwa\| PDB=3fwa \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
-	~~3FWA~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA].	+	[[3fwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA].
	[[Category: Eschscholzia californica]]		[[Category: Eschscholzia californica]]
	[[Category: Reticuline oxidase]]		[[Category: Reticuline oxidase]]
Line 29:		Line 22:
	[[Category: N-glycosylation]]		[[Category: N-glycosylation]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 18:01:01 2009''

OCA at 15:01, 20 May 2009

2009-05-20T15:01:04Z

←Older revision		Revision as of 15:01, 20 May 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3fwa.jpg\|left\|200px]]

-	The ~~entry 3fwa~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3fwa", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3fwa\| PDB=3fwa \| SCENE= }}

-	~~Authors: Winkler~~, ~~A., Macheroux, P., Gruber, K.~~	+	===Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline===

-	Description: Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Feb~~ 18 08:53:47 2009''	+	==About this Structure==
		+	3FWA is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Eschscholzia_californica Eschscholzia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWA OCA].
		+	[[Category: Eschscholzia californica]]
		+	[[Category: Reticuline oxidase]]
		+	[[Category: Gruber, K.]]
		+	[[Category: Macheroux, P.]]
		+	[[Category: Winkler, A.]]
		+	[[Category: Alakloid biosynthesis]]
		+	[[Category: Alkaloid metabolism]]
		+	[[Category: Bi-covalent flavinylation]]
		+	[[Category: Cytoplasmic vesicle]]
		+	[[Category: Fad]]
		+	[[Category: Flavoprotein]]
		+	[[Category: Glycoprotein]]
		+	[[Category: N-glycosylation]]
		+	[[Category: Oxidoreductase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 18:01:01 2009''

OCA at 06:53, 18 February 2009

2009-02-18T06:53:47Z

←Older revision		Revision as of 06:53, 18 February 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3fwa is ON HOLD	+	The entry 3fwa is ON HOLD until Paper Publication

	Authors: Winkler, A., Macheroux, P., Gruber, K.		Authors: Winkler, A., Macheroux, P., Gruber, K.
Line 7:		Line 7:
	Description: Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline		Description: Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb ~~4 11~~:26:59 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:53:47 2009''