3ga5 - Revision history

OCA at 15:37, 1 November 2023

2023-11-01T15:37:44Z

←Older revision		Revision as of 15:37, 1 November 2023
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	<StructureSection load='3ga5' size='340' side='right'caption='[[3ga5]], [[Resolution\|resolution]] 1.87Å' scene=''>		<StructureSection load='3ga5' size='340' side='right'caption='[[3ga5]], [[Resolution\|resolution]] 1.87Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ga5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3GA5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ga5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GA5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RGG:(2R)-2,3-DIHYDROXYPROPYL+BETA-D-GALACTOPYRANOSIDE'>RGG</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.87Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gca\|1gca]], [[1gcg\|1gcg]], [[3gbp\|3gbp]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RGG:(2R)-2,3-DIHYDROXYPROPYL+BETA-D-GALACTOPYRANOSIDE'>RGG</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga5 OCA], [~~http~~://pdbe.org/3ga5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ga5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ga5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ga5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga5 OCA], [https://pdbe.org/3ga5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ga5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ga5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ga5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~DGAL_SALTY DGAL_SALTY~~]~~] This protein is~~ involved in ~~the active transport of~~ galactose and glucose~~. It~~ plays a role in the chemotaxis towards ~~the~~ two sugars by interacting with the ~~trg~~ chemoreceptor.	+	[https://www.uniprot.org/uniprot/MGLB_SALTY MGLB_SALTY] Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import (By similarity). In addition, binds D-galactose and D-glucose and plays a role in the chemotaxis towards these two sugars by interacting with the Trg chemoreceptor (Probable).[UniProtKB:P0AEE5]<ref>PMID:8132630</ref> <ref>PMID:8240551</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Mowbray, S L]]~~	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-	~~[[Category: Sooriyaarachchi, S]]~~	+	[[Category: Mowbray SL]]
-	~~[[Category: Ubhayasekera, W]]~~	+	[[Category: Sooriyaarachchi S]]
-	~~[[Category: Calcium]]~~	+	[[Category: Ubhayasekera W]]
-	~~[[Category: Chemotaxis]]~~	+
-	~~[[Category: Glucose/galactose binding protein]]~~	+
-	~~[[Category: Glyceryl galactoside]]~~	+
-	~~[[Category: Periplasm]]~~	+
-	[[Category: Salmonella enterica serovar ~~typhimurium~~]]	+
-	[[Category: ~~Sugar binding protein~~]]	+
-	[[Category: ~~Sugar transport~~]]	+
-	[[Category: ~~Transport~~]]	+

OCA at 10:37, 9 September 2020

2020-09-09T10:37:56Z

←Older revision		Revision as of 10:37, 9 September 2020
Line 1:		Line 1:

	==X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with (2R)-glyceryl-beta-D-galactopyranoside==		==X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with (2R)-glyceryl-beta-D-galactopyranoside==
-	<StructureSection load='3ga5' size='340' side='right' caption='[[3ga5]], [[Resolution\|resolution]] 1.87Å' scene=''>	+	<StructureSection load='3ga5' size='340' side='right'caption='[[3ga5]], [[Resolution\|resolution]] 1.87Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ga5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA5 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3GA5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ga5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3GA5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RGG:(2R)-2,3-DIHYDROXYPROPYL+BETA-D-GALACTOPYRANOSIDE'>RGG</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RGG:(2R)-2,3-DIHYDROXYPROPYL+BETA-D-GALACTOPYRANOSIDE'>RGG</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gca\|1gca]], [[1gcg\|1gcg]], [[3gbp\|3gbp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gca\|1gca]], [[1gcg\|1gcg]], [[3gbp\|3gbp]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga5 OCA], [http://pdbe.org/3ga5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ga5 RCSB], [http://www.ebi.ac.uk/pdbsum/3ga5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ga5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga5 OCA], [http://pdbe.org/3ga5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ga5 RCSB], [http://www.ebi.ac.uk/pdbsum/3ga5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ga5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Mowbray, S L]]		[[Category: Mowbray, S L]]
	[[Category: Sooriyaarachchi, S]]		[[Category: Sooriyaarachchi, S]]

OCA at 05:09, 7 December 2018

2018-12-07T05:09:25Z

←Older revision		Revision as of 05:09, 7 December 2018
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/3ga5_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/3ga5_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 36:		Line 36:
	[[Category: Sooriyaarachchi, S]]		[[Category: Sooriyaarachchi, S]]
	[[Category: Ubhayasekera, W]]		[[Category: Ubhayasekera, W]]
		+	[[Category: Calcium]]
	[[Category: Chemotaxis]]		[[Category: Chemotaxis]]
	[[Category: Glucose/galactose binding protein]]		[[Category: Glucose/galactose binding protein]]
	[[Category: Glyceryl galactoside]]		[[Category: Glyceryl galactoside]]
		+	[[Category: Periplasm]]
	[[Category: Salmonella enterica serovar typhimurium]]		[[Category: Salmonella enterica serovar typhimurium]]
	[[Category: Sugar binding protein]]		[[Category: Sugar binding protein]]
	[[Category: Sugar transport]]		[[Category: Sugar transport]]
	[[Category: Transport]]		[[Category: Transport]]

OCA at 01:12, 5 August 2016

2016-08-05T01:12:55Z

←Older revision		Revision as of 01:12, 5 August 2016
Line 1:		Line 1:
		+
	==X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with (2R)-glyceryl-beta-D-galactopyranoside==		==X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with (2R)-glyceryl-beta-D-galactopyranoside==
	<StructureSection load='3ga5' size='340' side='right' caption='[[3ga5]], [[Resolution\|resolution]] 1.87Å' scene=''>		<StructureSection load='3ga5' size='340' side='right' caption='[[3ga5]], [[Resolution\|resolution]] 1.87Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ga5]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GA5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ga5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GA5 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RGG:(2R)-2,3-DIHYDROXYPROPYL+BETA-D-GALACTOPYRANOSIDE'>RGG</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RGG:(2R)-2,3-DIHYDROXYPROPYL+BETA-D-GALACTOPYRANOSIDE'>RGG</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gca\|1gca]], [[1gcg\|1gcg]], [[3gbp\|3gbp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gca\|1gca]], [[1gcg\|1gcg]], [[3gbp\|3gbp]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mglB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga5 OCA], [http://pdbe.org/3ga5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ga5 RCSB], [http://www.ebi.ac.uk/pdbsum/3ga5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ga5 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ga5 RCSB], [http://www.ebi.ac.uk/pdbsum/3ga5 PDBsum]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ga5 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ga5" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Mowbray, S L]]		[[Category: Mowbray, S L]]
	[[Category: Sooriyaarachchi, S]]		[[Category: Sooriyaarachchi, S]]

OCA at 14:37, 25 December 2014

2014-12-25T14:37:07Z

←Older revision		Revision as of 14:37, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ga5 RCSB], [http://www.ebi.ac.uk/pdbsum/3ga5 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ga5 RCSB], [http://www.ebi.ac.uk/pdbsum/3ga5 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DGAL_SALTY DGAL_SALTY]] This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:03, 3 December 2014

2014-12-03T10:03:48Z

←Older revision		Revision as of 10:03, 3 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3ga5.~~png~~\|~~left~~\|200px]]	+	==X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with (2R)-glyceryl-beta-D-galactopyranoside==
		+	<StructureSection load='3ga5' size='340' side='right' caption='[[3ga5]], [[Resolution\|resolution]] 1.87Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ga5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GA5 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RGG:(2R)-2,3-DIHYDROXYPROPYL+BETA-D-GALACTOPYRANOSIDE'>RGG</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gca\|1gca]], [[1gcg\|1gcg]], [[3gbp\|3gbp]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mglB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ga5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ga5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ga5 RCSB], [http://www.ebi.ac.uk/pdbsum/3ga5 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/3ga5_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Periplasmic binding proteins are abundant in bacteria by virtue of their essential roles as high-affinity receptors in ABC transport systems and chemotaxis. One of the best studied of these receptors is the so-called glucose/galactose-binding protein. Here, we report the X-ray structure of the Salmonella typhimurium protein bound to the physiologically relevant ligand, (2R)-glyceryl-beta-D-galactopyranoside, solved by molecular replacement, and refined to 1.87 A resolution with R and R-free values of 17% and 22%. The structure identifies three amino acid residues that are diagnostic of (2R)-glyceryl-beta-D-galactopyranoside binding (Thr110, Asp154 and Gln261), as opposed to binding to the monosaccharides glucose and galactose. These three residues are conserved in essentially all available glucose/galactose-binding protein sequences, indicating that the binding of (2R)-glyceryl-beta-D-galactopyranoside is the rule rather than the exception for receptors of this type. The role of (2R)-glyceryl-beta-D-galactopyranoside in bacterial biology is discussed. Further, comparison of the available structures provides the most complete description of the conformational changes of glucose/galactose-binding protein to date. The structures follow a smooth and continuous path from the most closed structure [that bound to (2R)-glyceryl-beta-D-galactopyranoside] to the most open (an apo structure).

-	~~{{STRUCTURE_3ga5\| PDB=3ga5 \| SCENE= }}~~	+	X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-beta-D-galactopyranoside.,Sooriyaarachchi S, Ubhayasekera W, Boos W, Mowbray SL FEBS J. 2009 Apr;276(7):2116-24. PMID:19292879<ref>PMID:19292879</ref>

-	~~===X-ray structure of glucose~~/~~galactose receptor from Salmonella typhimurium in complex with (2R)-glyceryl-beta-D-galactopyranoside===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19292879}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3ga5]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Salmonella_enterica_subsp~~.~~_enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3GA5 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019292879<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
-	[[Category: Mowbray, S L.]]	+	[[Category: Mowbray, S L]]
-	[[Category: Sooriyaarachchi, S.]]	+	[[Category: Sooriyaarachchi, S]]
-	[[Category: Ubhayasekera, W.]]	+	[[Category: Ubhayasekera, W]]
	[[Category: Chemotaxis]]		[[Category: Chemotaxis]]
	[[Category: Glucose/galactose binding protein]]		[[Category: Glucose/galactose binding protein]]

OCA: Protected "3ga5" [edit=sysop:move=sysop]

2013-02-20T14:10:24Z

Protected "3ga5" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:10, 20 February 2013

OCA at 14:10, 20 February 2013

2013-02-20T14:10:19Z

←Older revision		Revision as of 14:10, 20 February 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3ga5.png\|left\|200px]]		[[Image:3ga5.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ga5", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ga5\| PDB=3ga5 \| SCENE= }}		{{STRUCTURE_3ga5\| PDB=3ga5 \| SCENE= }}

	===X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with (2R)-glyceryl-beta-D-galactopyranoside===		===X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with (2R)-glyceryl-beta-D-galactopyranoside===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19292879}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19292879 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19292879}}		{{ABSTRACT_PUBMED_19292879}}

	==About this Structure==		==About this Structure==
-	~~3GA5~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA5 OCA].	+	[[3ga5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA5 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19292879~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019292879</ref><references group="xtra"/>
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Mowbray, S L.]]		[[Category: Mowbray, S L.]]
	[[Category: Sooriyaarachchi, S.]]		[[Category: Sooriyaarachchi, S.]]
	[[Category: Ubhayasekera, W.]]		[[Category: Ubhayasekera, W.]]
-	[[Category: Calcium]]
	[[Category: Chemotaxis]]		[[Category: Chemotaxis]]
	[[Category: Glucose/galactose binding protein]]		[[Category: Glucose/galactose binding protein]]
	[[Category: Glyceryl galactoside]]		[[Category: Glyceryl galactoside]]
-	[[Category: Periplasm]]
	[[Category: Salmonella enterica serovar typhimurium]]		[[Category: Salmonella enterica serovar typhimurium]]
	[[Category: Sugar binding protein]]		[[Category: Sugar binding protein]]
	[[Category: Sugar transport]]		[[Category: Sugar transport]]
	[[Category: Transport]]		[[Category: Transport]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 09:54:04 2009''

OCA at 06:54, 6 May 2009

2009-05-06T06:54:05Z

←Older revision		Revision as of 06:54, 6 May 2009
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3ga5.~~jpg~~\|left\|200px]]	+	[[Image:3ga5.png\|left\|200px]]

	<!--		<!--
Line 38:		Line 38:
	[[Category: Transport]]		[[Category: Transport]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Apr 15 10~~:12:11 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 09:54:04 2009''

OCA at 07:12, 15 April 2009

2009-04-15T07:12:13Z

←Older revision		Revision as of 07:12, 15 April 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3ga5.jpg\|left\|200px]]

-	The ~~entry 3ga5~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3ga5", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3ga5\| PDB=3ga5 \| SCENE= }}

-	~~Authors: Sooriyaarachchi, S., Ubhayasekera, W., Boos, W., Mowbray, S.L.~~	+	===X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with (2R)-glyceryl-beta-D-galactopyranoside===

-	Description: X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with (2R)-glyceryl-beta-D-galactopyranoside

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Mar 22~~ 10:24:11 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19292879}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19292879 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19292879}}
		+
		+	==About this Structure==
		+	3GA5 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GA5 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19292879</ref><references group="xtra"/>
		+	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
		+	[[Category: Mowbray, S L.]]
		+	[[Category: Sooriyaarachchi, S.]]
		+	[[Category: Ubhayasekera, W.]]
		+	[[Category: Calcium]]
		+	[[Category: Chemotaxis]]
		+	[[Category: Glucose/galactose binding protein]]
		+	[[Category: Glyceryl galactoside]]
		+	[[Category: Periplasm]]
		+	[[Category: Salmonella enterica serovar typhimurium]]
		+	[[Category: Sugar binding protein]]
		+	[[Category: Sugar transport]]
		+	[[Category: Transport]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 15 10:12:11 2009''