3gqg - Revision history

OCA at 07:09, 6 September 2023

2023-09-06T07:09:57Z

←Older revision		Revision as of 07:09, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3gqg' size='340' side='right'caption='[[3gqg]], [[Resolution\|resolution]] 1.73Å' scene=''>		<StructureSection load='3gqg' size='340' side='right'caption='[[3gqg]], [[Resolution\|resolution]] 1.73Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gqg]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3GQG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gqg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GQG FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.73Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3gqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gqg OCA], [~~http~~://pdbe.org/3gqg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3gqg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3gqg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3gqg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gqg OCA], [https://pdbe.org/3gqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gqg RCSB], [https://www.ebi.ac.uk/pdbsum/3gqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gqg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/HBA_TREBE HBA_TREBE~~]] Involved in oxygen transport from gills to the various peripheral tissues. [[http://www.uniprot.org/uniprot/HBB_TREBE HBB_TREBE]~~] Involved in oxygen transport from gills to the various peripheral tissues.	+	[https://www.uniprot.org/uniprot/HBA_TREBE HBA_TREBE] Involved in oxygen transport from gills to the various peripheral tissues.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 38:		Line 38:
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Trematomus bernacchii]]		[[Category: Trematomus bernacchii]]
-	[[Category: Bonomi, G]]	+	[[Category: Bonomi G]]
-	[[Category: Franzese, M]]	+	[[Category: Franzese M]]
-	[[Category: Mazzarella, L]]	+	[[Category: Mazzarella L]]
-	[[Category: Merlino, A]]	+	[[Category: Merlino A]]
-	[[Category: Vergara, A]]	+	[[Category: Vergara A]]
-	~~[[Category: Acetylation]]~~	+
-	~~[[Category: Antacrtic fish hemoglobin]]~~	+
-	~~[[Category: Heme]]~~	+
-	~~[[Category: Iron]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Oxygen transport]]~~	+
-	~~[[Category: Transport~~]]	+

OCA at 10:41, 9 September 2020

2020-09-09T10:41:01Z

←Older revision		Revision as of 10:41, 9 September 2020
Line 1:		Line 1:

	==Crystal structure at acidic pH of the ferric form of the Root effect hemoglobin from Trematomus bernacchii.==		==Crystal structure at acidic pH of the ferric form of the Root effect hemoglobin from Trematomus bernacchii.==
-	<StructureSection load='3gqg' size='340' side='right' caption='[[3gqg]], [[Resolution\|resolution]] 1.73Å' scene=''>	+	<StructureSection load='3gqg' size='340' side='right'caption='[[3gqg]], [[Resolution\|resolution]] 1.73Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gqg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3GQG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gqg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3GQG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3gqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gqg OCA], [http://pdbe.org/3gqg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gqg RCSB], [http://www.ebi.ac.uk/pdbsum/3gqg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gqg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3gqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gqg OCA], [http://pdbe.org/3gqg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gqg RCSB], [http://www.ebi.ac.uk/pdbsum/3gqg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gqg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 36:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Trematomus bernacchii]]		[[Category: Trematomus bernacchii]]
	[[Category: Bonomi, G]]		[[Category: Bonomi, G]]

OCA at 06:05, 7 December 2018

2018-12-07T06:05:03Z

←Older revision		Revision as of 06:05, 7 December 2018
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gq/3gqg_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gq/3gqg_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 42:		Line 42:
	[[Category: Merlino, A]]		[[Category: Merlino, A]]
	[[Category: Vergara, A]]		[[Category: Vergara, A]]
		+	[[Category: Acetylation]]
	[[Category: Antacrtic fish hemoglobin]]		[[Category: Antacrtic fish hemoglobin]]
	[[Category: Heme]]		[[Category: Heme]]

OCA at 10:25, 5 August 2016

2016-08-05T10:25:11Z

←Older revision		Revision as of 10:25, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure at acidic pH of the ferric form of the Root effect hemoglobin from Trematomus bernacchii.==		==Crystal structure at acidic pH of the ferric form of the Root effect hemoglobin from Trematomus bernacchii.==
	<StructureSection load='3gqg' size='340' side='right' caption='[[3gqg]], [[Resolution\|resolution]] 1.73Å' scene=''>		<StructureSection load='3gqg' size='340' side='right' caption='[[3gqg]], [[Resolution\|resolution]] 1.73Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gqg RCSB], [http://www.ebi.ac.uk/pdbsum/3gqg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gqg OCA], [http://pdbe.org/3gqg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gqg RCSB], [http://www.ebi.ac.uk/pdbsum/3gqg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gqg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~HBA_PAGBE HBA_PAGBE~~]] Involved in oxygen transport from gills to the various peripheral tissues. [[http://www.uniprot.org/uniprot/~~HBB_PAGBE HBB_PAGBE~~]] Involved in oxygen transport from gills to the various peripheral tissues.	+	[[http://www.uniprot.org/uniprot/HBA_TREBE HBA_TREBE]] Involved in oxygen transport from gills to the various peripheral tissues. [[http://www.uniprot.org/uniprot/HBB_TREBE HBB_TREBE]] Involved in oxygen transport from gills to the various peripheral tissues.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 17:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gqg ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3gqg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 18:01, 25 December 2014

2014-12-25T18:01:25Z

←Older revision		Revision as of 18:01, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3gqg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GQG FirstGlance]. <br>		<table><tr><td colspan='2'>[[3gqg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GQG FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gqg RCSB], [http://www.ebi.ac.uk/pdbsum/3gqg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gqg RCSB], [http://www.ebi.ac.uk/pdbsum/3gqg PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HBA_PAGBE HBA_PAGBE]] Involved in oxygen transport from gills to the various peripheral tissues. [[http://www.uniprot.org/uniprot/HBB_PAGBE HBB_PAGBE]] Involved in oxygen transport from gills to the various peripheral tissues.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Trematomus bernacchii]]		[[Category: Trematomus bernacchii]]
-	[[Category: Bonomi, G.]]	+	[[Category: Bonomi, G]]
-	[[Category: Franzese, M.]]	+	[[Category: Franzese, M]]
-	[[Category: Mazzarella, L.]]	+	[[Category: Mazzarella, L]]
-	[[Category: Merlino, A.]]	+	[[Category: Merlino, A]]
-	[[Category: Vergara, A.]]	+	[[Category: Vergara, A]]
	[[Category: Antacrtic fish hemoglobin]]		[[Category: Antacrtic fish hemoglobin]]
	[[Category: Heme]]		[[Category: Heme]]

OCA at 13:40, 29 September 2014

2014-09-29T13:40:02Z

←Older revision		Revision as of 13:40, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~3gqg.~~png~~\|~~left~~\|200px]]	+	==Crystal structure at acidic pH of the ferric form of the Root effect hemoglobin from Trematomus bernacchii.==
		+	<StructureSection load='3gqg' size='340' side='right' caption='[[3gqg]], [[Resolution\|resolution]] 1.73Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3gqg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GQG FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gqg RCSB], [http://www.ebi.ac.uk/pdbsum/3gqg PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gq/3gqg_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Oxidation of Hbs leads to the formation of different forms of Fe(III) that are relevant to a range of biochemical and physiological functions. Here we report a combined EPR/x-ray crystallography study performed at acidic pH on six ferric tetrameric Hbs. Five of the Hbs were isolated from the high-Antarctic notothenioid fishes Trematomus bernacchii, Trematomus newnesi, and Gymnodraco acuticeps, and one was isolated from the sub-Antarctic notothenioid Cottoperca gobio. Our EPR analysis reveals that 1), in all of these Hbs, at acidic pH the aquomet form and two hemichromes coexist; and 2), only in the three Hbs that exhibit the Root effect is a significant amount of the pentacoordinate (5C) high-spin Fe(III) form found. The crystal structure at acidic pH of the ferric form of the Root-effect Hb from T. bernacchii is also reported at 1.7 A resolution. This structure reveals a 5C state of the heme iron for both the alpha- and beta-chains within a T quaternary structure. Altogether, the spectroscopic and crystallographic results indicate that the Root effect and hemichrome stability at acidic pH are correlated in tetrameric Hbs. Furthermore, Antarctic fish Hbs exhibit higher peroxidase activity than mammalian and temperate fish Hbs, suggesting that a partial hemichrome state in tetrameric Hbs, unlike in monomeric Hbs, does not remove the need for protection from peroxide attack, in contrast to previous results from monomeric Hbs.

-	~~{{STRUCTURE_3gqg\| PDB=3gqg \| SCENE= }}~~	+	Correlation between hemichrome stability and the root effect in tetrameric hemoglobins.,Vergara A, Franzese M, Merlino A, Bonomi G, Verde C, Giordano D, di Prisco G, Lee HC, Peisach J, Mazzarella L Biophys J. 2009 Aug 5;97(3):866-74. PMID:19651045<ref>PMID:19651045</ref>

-	~~===Crystal structure at acidic pH~~ of the ~~ferric form~~ of ~~the Root effect hemoglobin from Trematomus bernacchii~~.~~===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19651045}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3gqg]] is a 4 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA].~~	+

	==See Also==		==See Also==
-	*[[Hemoglobin\|Hemoglobin]]	+	*[[Hemoglobin 3D structures\|Hemoglobin 3D structures]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019651045<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Trematomus bernacchii]]		[[Category: Trematomus bernacchii]]
	[[Category: Bonomi, G.]]		[[Category: Bonomi, G.]]

OCA at 19:44, 20 October 2012

2012-10-20T19:44:38Z

←Older revision		Revision as of 19:44, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3gqg]] is a 4 chain structure ~~of [[Hemoglobin]]~~ with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA].	+	[[3gqg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA].

	==See Also==		==See Also==

OCA: Protected "3gqg" [edit=sysop:move=sysop]

2012-07-27T08:20:12Z

Protected "3gqg" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:20, 27 July 2012

OCA at 08:20, 27 July 2012

2012-07-27T08:20:10Z

←Older revision		Revision as of 08:20, 27 July 2012
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3gqg.png\|left\|200px]]
-	[[Image:3gqg.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3gqg", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3gqg\| PDB=3gqg \| SCENE= }}		{{STRUCTURE_3gqg\| PDB=3gqg \| SCENE= }}

	===Crystal structure at acidic pH of the ferric form of the Root effect hemoglobin from Trematomus bernacchii.===		===Crystal structure at acidic pH of the ferric form of the Root effect hemoglobin from Trematomus bernacchii.===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19651045}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19651045 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19651045}}		{{ABSTRACT_PUBMED_19651045}}

	==About this Structure==		==About this Structure==
-	~~3GQG~~ is a 4 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA].	+	[[3gqg]] is a 4 chain structure of [[Hemoglobin]] with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA].
		+
		+	==See Also==
		+	*[[Hemoglobin\|Hemoglobin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19651045~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019651045</ref><references group="xtra"/>
	[[Category: Trematomus bernacchii]]		[[Category: Trematomus bernacchii]]
	[[Category: Bonomi, G.]]		[[Category: Bonomi, G.]]
Line 30:		Line 21:
	[[Category: Merlino, A.]]		[[Category: Merlino, A.]]
	[[Category: Vergara, A.]]		[[Category: Vergara, A.]]
-	[[Category: Acetylation]]
	[[Category: Antacrtic fish hemoglobin]]		[[Category: Antacrtic fish hemoglobin]]
	[[Category: Heme]]		[[Category: Heme]]
Line 37:		Line 27:
	[[Category: Oxygen transport]]		[[Category: Oxygen transport]]
	[[Category: Transport]]		[[Category: Transport]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:26:21 2009''

OCA at 08:26, 14 October 2009

2009-10-14T08:26:22Z

←Older revision		Revision as of 08:26, 14 October 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3gqg.jpg\|left\|200px]]

-	The ~~entry 3gqg~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3gqg", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3gqg\| PDB=3gqg \| SCENE= }}

-	~~Authors: Vergara, A., Franzese, M., Merlino, A., Bonomi, G., Mazzarella, L~~.	+	===Crystal structure at acidic pH of the ferric form of the Root effect hemoglobin from Trematomus bernacchii.===

-	Description: Crystal structure at acidic pH of the ferric form of the Root effect hemoglobin from Trematomus bernacchii.

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jul 8 09~~:13:42 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19651045}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19651045 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19651045}}
		+
		+	==About this Structure==
		+	3GQG is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQG OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19651045</ref><references group="xtra"/>
		+	[[Category: Trematomus bernacchii]]
		+	[[Category: Bonomi, G.]]
		+	[[Category: Franzese, M.]]
		+	[[Category: Mazzarella, L.]]
		+	[[Category: Merlino, A.]]
		+	[[Category: Vergara, A.]]
		+	[[Category: Acetylation]]
		+	[[Category: Antacrtic fish hemoglobin]]
		+	[[Category: Heme]]
		+	[[Category: Iron]]
		+	[[Category: Metal-binding]]
		+	[[Category: Oxygen transport]]
		+	[[Category: Transport]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:26:21 2009''