3hd8 - Revision history

OCA at 15:48, 1 November 2023

2023-11-01T15:48:20Z

←Older revision		Revision as of 15:48, 1 November 2023
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	<StructureSection load='3hd8' size='340' side='right'caption='[[3hd8]], [[Resolution\|resolution]] 2.39Å' scene=''>		<StructureSection load='3hd8' size='340' side='right'caption='[[3hd8]], [[Resolution\|resolution]] 2.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hd8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"vibrio_subtilis"_ehrenberg_1835 "vibrio~~ subtilis~~" ehrenberg 1835~~] and [https://en.wikipedia.org/wiki/~~Canadian_hard_winter_wheat Canadian hard winter wheat~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HD8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hd8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [https://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HD8 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1t6e\|1t6e]], [[1t6g\|1t6g]], [[2b42\|2b42]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.39Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">XYNA ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=4565 Canadian hard winter wheat]), xynA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hd8 OCA], [https://pdbe.org/3hd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hd8 RCSB], [https://www.ebi.ac.uk/pdbsum/3hd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hd8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hd8 OCA], [https://pdbe.org/3hd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hd8 RCSB], [https://www.ebi.ac.uk/pdbsum/3hd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hd8 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q53IQ4_WHEAT Q53IQ4_WHEAT]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Vibrio~~ subtilis ~~ehrenberg 1835]]~~	+	[[Category: Bacillus subtilis]]
-	~~[[Category: Canadian hard winter wheat]]~~	+
-	~~[[Category: Endo-1,4-beta-xylanase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Courtin~~, C M~~]]	+	[[Category: Triticum aestivum]]
-	[[Category: Gebruers, K]]	+	[[Category: Courtin CM]]
-	[[Category: Pollet, A]]	+	[[Category: Gebruers K]]
-	[[Category: Rabijns, A]]	+	[[Category: Pollet A]]
-	[[Category: Raedschelders, G]]	+	[[Category: Rabijns A]]
-	[[Category: Sansen, S]]	+	[[Category: Raedschelders G]]
-	~~[[Category: Beta-jelly roll]]~~	+	[[Category: Sansen S]]
-	~~[[Category: Glycosidase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hydrolase inhibitor-hydrolase complex]]~~	+
-	~~[[Category: Protein-protein complex]]~~	+
-	~~[[Category: Two beta-barrel domain]]~~	+
-	~~[[Category: Xylan degradation~~]]	+

OCA at 12:45, 23 March 2022

2022-03-23T12:45:05Z

←Older revision		Revision as of 12:45, 23 March 2022
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	==Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase==		==Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase==
-	<StructureSection load='3hd8' size='340' side='right' caption='[[3hd8]], [[Resolution\|resolution]] 2.39Å' scene=''>	+	<StructureSection load='3hd8' size='340' side='right'caption='[[3hd8]], [[Resolution\|resolution]] 2.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hd8]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835] and [~~http~~://en.wikipedia.org/wiki/Canadian_hard_winter_wheat Canadian hard winter wheat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3HD8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hd8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835] and [https://en.wikipedia.org/wiki/Canadian_hard_winter_wheat Canadian hard winter wheat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HD8 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t6e\|1t6e]], [[1t6g\|1t6g]], [[2b42\|2b42]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1t6e\|1t6e]], [[1t6g\|1t6g]], [[2b42\|2b42]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">XYNA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4565 Canadian hard winter wheat]), xynA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">XYNA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4565 Canadian hard winter wheat]), xynA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3hd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hd8 OCA], [~~http~~://pdbe.org/3hd8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3hd8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3hd8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3hd8 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hd8 OCA], [https://pdbe.org/3hd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hd8 RCSB], [https://www.ebi.ac.uk/pdbsum/3hd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hd8 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	[[Category: Canadian hard winter wheat]]		[[Category: Canadian hard winter wheat]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
		+	[[Category: Large Structures]]
	[[Category: Courtin, C M]]		[[Category: Courtin, C M]]
	[[Category: Gebruers, K]]		[[Category: Gebruers, K]]

OCA at 07:54, 12 December 2018

2018-12-12T07:54:00Z

←Older revision		Revision as of 07:54, 12 December 2018
Line 1:		Line 1:
		+
	==Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase==		==Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase==
	<StructureSection load='3hd8' size='340' side='right' caption='[[3hd8]], [[Resolution\|resolution]] 2.39Å' scene=''>		<StructureSection load='3hd8' size='340' side='right' caption='[[3hd8]], [[Resolution\|resolution]] 2.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hd8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"~~bacillus_globigii~~"~~_migula_1900~~ "~~bacillus globigii~~" ~~migula 1900~~] and [http://en.wikipedia.org/wiki/Canadian_hard_winter_wheat Canadian hard winter wheat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HD8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hd8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835] and [http://en.wikipedia.org/wiki/Canadian_hard_winter_wheat Canadian hard winter wheat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HD8 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t6e\|1t6e]], [[1t6g\|1t6g]], [[2b42\|2b42]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t6e\|1t6e]], [[1t6g\|1t6g]], [[2b42\|2b42]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">XYNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4565 Canadian hard winter wheat]), xynA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "~~Bacillus globigii~~" ~~Migula 1900~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">XYNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4565 Canadian hard winter wheat]), xynA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hd8 OCA], [http://pdbe.org/3hd8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hd8 RCSB], [http://www.ebi.ac.uk/pdbsum/3hd8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hd8 OCA], [http://pdbe.org/3hd8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hd8 RCSB], [http://www.ebi.ac.uk/pdbsum/3hd8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hd8 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hd/3hd8_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hd/3hd8_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus globigii migula 1900~~]]	+	[[Category: Vibrio subtilis ehrenberg 1835]]
	[[Category: Canadian hard winter wheat]]		[[Category: Canadian hard winter wheat]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]

OCA at 13:07, 9 February 2016

2016-02-09T13:07:47Z

←Older revision		Revision as of 13:07, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3hd8' size='340' side='right' caption='[[3hd8]], [[Resolution\|resolution]] 2.39Å' scene=''>		<StructureSection load='3hd8' size='340' side='right' caption='[[3hd8]], [[Resolution\|resolution]] 2.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hd8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_subtilis Bacillus subtilis~~] and [http://en.wikipedia.org/wiki/~~Triticum_aestivum Triticum aestivum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HD8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hd8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900] and [http://en.wikipedia.org/wiki/Canadian_hard_winter_wheat Canadian hard winter wheat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HD8 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t6e\|1t6e]], [[1t6g\|1t6g]], [[2b42\|2b42]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t6e\|1t6e]], [[1t6g\|1t6g]], [[2b42\|2b42]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">XYNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4565 ~~Triticum aestivum~~]), xynA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus ~~subtilis~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">XYNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4565 Canadian hard winter wheat]), xynA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hd8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hd8 RCSB], [http://www.ebi.ac.uk/pdbsum/3hd8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hd8 OCA], [http://pdbe.org/3hd8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hd8 RCSB], [http://www.ebi.ac.uk/pdbsum/3hd8 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hd8 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3hd8" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus ~~subtilis~~]]	+	[[Category: Bacillus globigii migula 1900]]
		+	[[Category: Canadian hard winter wheat]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
-	[[Category: Triticum aestivum]]
	[[Category: Courtin, C M]]		[[Category: Courtin, C M]]
	[[Category: Gebruers, K]]		[[Category: Gebruers, K]]

OCA at 09:05, 8 December 2014

2014-12-08T09:05:24Z

←Older revision		Revision as of 09:05, 8 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3hd8.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase==
		+	<StructureSection load='3hd8' size='340' side='right' caption='[[3hd8]], [[Resolution\|resolution]] 2.39Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3hd8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HD8 FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t6e\|1t6e]], [[1t6g\|1t6g]], [[2b42\|2b42]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">XYNA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4565 Triticum aestivum]), xynA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hd8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hd8 RCSB], [http://www.ebi.ac.uk/pdbsum/3hd8 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hd/3hd8_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Triticum aestivum xylanase inhibitor (TAXI)-type inhibitors are active against microbial xylanases from glycoside hydrolase family 11, but the inhibition strength and the specificity towards different xylanases differ between TAXI isoforms. Mutational and biochemical analyses of TAXI-I, TAXI-IIA and Bacillus subtilis xylanase A showed that inhibition strength and specificity depend on the identity of only a few key residues of inhibitor and xylanase [Fierens K et al. (2005) FEBS J 272, 5872-5882; Raedschelders G et al. (2005) Biochem Biophys Res Commun335, 512-522; Sorensen JF & Sibbesen O (2006) Protein Eng Des Sel 19, 205-210; Bourgois TM et al. (2007) J Biotechnol 130, 95-105]. Crystallographic analysis of the structures of TAXI-IA and TAXI-IIA in complex with glycoside hydrolase family 11 B. subtilis xylanase A now provides a substantial explanation for these observations and a detailed insight into the structural determinants for inhibition strength and specificity. Structures of the xylanaseinhibitor complexes show that inhibition is established by loop interactions with active-site residues and substrate-mimicking contacts in the binding subsites. The interaction of residues Leu292 of TAXI-IA and Pro294 of TAXI-IIA with the -2 glycon subsite of the xylanase is shown to be critical for both inhibition strength and specificity. Also, detailed analysis of the interaction interfaces of the complexes illustrates that the inhibition strength of TAXI is related to the presence of an aspartate or asparagine residue adjacent to the acid/base catalyst of the xylanase, and therefore to the pH optimum of the xylanase. The lower the pH optimum of the xylanase, the stronger will be the interaction between enzyme and inhibitor, and the stronger the resulting inhibition.

-	~~{{STRUCTURE_3hd8\| PDB=3hd8 \| SCENE= }}~~	+	Identification of structural determinants for inhibition strength and specificity of wheat xylanase inhibitors TAXI-IA and TAXI-IIA.,Pollet A, Sansen S, Raedschelders G, Gebruers K, Rabijns A, Delcour JA, Courtin CM FEBS J. 2009 Jul;276(14):3916-27. Epub 2009 Jun 17. PMID:19769747<ref>PMID:19769747</ref>

-	~~===Crystal structure~~ of the ~~Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19769747}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3hd8]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_subtilis Bacillus subtilis] and [http://en~~.~~wikipedia.org~~/~~wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019769747<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
	[[Category: Triticum aestivum]]		[[Category: Triticum aestivum]]
-	[[Category: Courtin, C M.]]	+	[[Category: Courtin, C M]]
-	[[Category: Gebruers, K.]]	+	[[Category: Gebruers, K]]
-	[[Category: Pollet, A.]]	+	[[Category: Pollet, A]]
-	[[Category: Rabijns, A.]]	+	[[Category: Rabijns, A]]
-	[[Category: Raedschelders, G.]]	+	[[Category: Raedschelders, G]]
-	[[Category: Sansen, S.]]	+	[[Category: Sansen, S]]
	[[Category: Beta-jelly roll]]		[[Category: Beta-jelly roll]]
	[[Category: Glycosidase]]		[[Category: Glycosidase]]

OCA: Protected "3hd8" [edit=sysop:move=sysop]

2013-03-06T14:59:43Z

Protected "3hd8" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:59, 6 March 2013

OCA at 14:59, 6 March 2013

2013-03-06T14:59:40Z

←Older revision		Revision as of 14:59, 6 March 2013
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-	{{Seed}}
	[[Image:3hd8.png\|left\|200px]]		[[Image:3hd8.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3hd8", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3hd8\| PDB=3hd8 \| SCENE= }}		{{STRUCTURE_3hd8\| PDB=3hd8 \| SCENE= }}

	===Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase===		===Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19769747}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19769747 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19769747}}		{{ABSTRACT_PUBMED_19769747}}

	==About this Structure==		==About this Structure==
-	~~3HD8~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA].	+	[[3hd8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19769747~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019769747</ref><references group="xtra"/>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
Line 40:		Line 28:
	[[Category: Two beta-barrel domain]]		[[Category: Two beta-barrel domain]]
	[[Category: Xylan degradation]]		[[Category: Xylan degradation]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 30 13:16:50 2010''

OCA at 09:11, 30 June 2010

2010-06-30T09:11:14Z

←Older revision		Revision as of 09:11, 30 June 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3hd8.~~jpg~~\|left\|200px]]	+	[[Image:3hd8.png\|left\|200px]]

	<!--		<!--
Line 12:		Line 12:
	===Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase===		===Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19769747}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19769747 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19769747}}

	==About this Structure==		==About this Structure==
-	3HD8 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA].	+	3HD8 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19769747</ref><references group="xtra"/>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
Line 27:		Line 36:
	[[Category: Glycosidase]]		[[Category: Glycosidase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
-	[[Category: Hydrolase inhibitor/hydrolase complex]]	+	[[Category: Hydrolase inhibitor-hydrolase complex]]
	[[Category: Protein-protein complex]]		[[Category: Protein-protein complex]]
	[[Category: Two beta-barrel domain]]		[[Category: Two beta-barrel domain]]
-	[[Category: X-ray crystallography]]
	[[Category: Xylan degradation]]		[[Category: Xylan degradation]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jul 1 09~~:41:~~10 2009~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 30 13:16:50 2010''

OCA at 06:41, 1 July 2009

2009-07-01T06:41:11Z

←Older revision		Revision as of 06:41, 1 July 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3hd8.jpg\|left\|200px]]

-	The ~~entry 3hd8~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3hd8", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3hd8\| PDB=3hd8 \| SCENE= }}

-	~~Authors: Sansen, S., Pollet, A., Raedschelders, G., Gebruers, K., Rabijns, A., Courtin, C.M.~~	+	===Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase===

-	Description: Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 10 17~~:58:43 2009''	+	==About this Structure==
		+	3HD8 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD8 OCA].
		+	[[Category: Bacillus subtilis]]
		+	[[Category: Endo-1,4-beta-xylanase]]
		+	[[Category: Triticum aestivum]]
		+	[[Category: Courtin, C M.]]
		+	[[Category: Gebruers, K.]]
		+	[[Category: Pollet, A.]]
		+	[[Category: Rabijns, A.]]
		+	[[Category: Raedschelders, G.]]
		+	[[Category: Sansen, S.]]
		+	[[Category: Beta-jelly roll]]
		+	[[Category: Glycosidase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolase inhibitor/hydrolase complex]]
		+	[[Category: Protein-protein complex]]
		+	[[Category: Two beta-barrel domain]]
		+	[[Category: X-ray crystallography]]
		+	[[Category: Xylan degradation]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 1 09:41:10 2009''

OCA at 14:58, 10 June 2009

2009-06-10T14:58:43Z

←Older revision		Revision as of 14:58, 10 June 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3hd8 is ON HOLD	+	The entry 3hd8 is ON HOLD until Paper Publication

	Authors: Sansen, S., Pollet, A., Raedschelders, G., Gebruers, K., Rabijns, A., Courtin, C.M.		Authors: Sansen, S., Pollet, A., Raedschelders, G., Gebruers, K., Rabijns, A., Courtin, C.M.
Line 7:		Line 7:
	Description: Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase		Description: Crystal structure of the Triticum aestivum xylanase inhibitor-IIA in complex with bacillus subtilis xylanase

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~May 20 16~~:39:41 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 17:58:43 2009''