3hoe - Revision history

OCA at 10:01, 21 February 2024

2024-02-21T10:01:01Z

←Older revision		Revision as of 10:01, 21 February 2024
Line 3:		Line 3:
	<StructureSection load='3hoe' size='340' side='right'caption='[[3hoe]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3hoe' size='340' side='right'caption='[[3hoe]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hoe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Actpl Actpl~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HOE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hoe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinobacillus_pleuropneumoniae Actinobacillus pleuropneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HOE FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3hol\|3hol]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.303Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">tbpB ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=715 ACTPL])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hoe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hoe OCA], [https://pdbe.org/3hoe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hoe RCSB], [https://www.ebi.ac.uk/pdbsum/3hoe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hoe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hoe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hoe OCA], [https://pdbe.org/3hoe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hoe RCSB], [https://www.ebi.ac.uk/pdbsum/3hoe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hoe ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q44124_ACTPL Q44124_ACTPL]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hoe ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hoe ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Pathogenic bacteria from the Neisseriaceae and Pasteurellacea families acquire iron directly from the host iron-binding glycoprotein, transferrin (Tf), in a process mediated by surface receptor proteins that directly bind host Tf, extract the iron, and transport it across the outer membrane. The bacterial Tf receptor is comprised of a surface exposed lipoprotein, Tf-binding protein B (TbpB), and an integral outer-membrane protein, Tf-binding protein A (TbpA), both of which are essential for survival in the host. In this study, we report the 1.98 A resolution structure of TbpB from the porcine pathogen Actinobacillus pleuropneumoniae, providing insights into the mechanism of Tf binding and the role of TbpB. A model for the complex of TbpB bound to Tf is proposed. Mutation of a single surface-exposed Phe residue on TbpB within the predicted interface completely abolishes binding to Tf, suggesting that the TbpB N lobe comprises the sole high-affinity binding region for Tf.
-
-	Insights into the bacterial transferrin receptor: the structure of transferrin-binding protein B from Actinobacillus pleuropneumoniae.,Moraes TF, Yu RH, Strynadka NC, Schryvers AB Mol Cell. 2009 Aug 28;35(4):523-33. PMID:19716795<ref>PMID:19716795</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3hoe" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Transferrin-binding protein\|Transferrin-binding protein]]		*[[Transferrin-binding protein\|Transferrin-binding protein]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Actpl~~]]	+	[[Category: Actinobacillus pleuropneumoniae]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Moraes~~, T F~~]]	+	[[Category: Moraes TF]]
-	[[Category: Schryvers~~, A B~~]]	+	[[Category: Schryvers AB]]
-	[[Category: Strynadka~~, N C.J~~]]	+	[[Category: Strynadka NCJ]]
-	[[Category: Yu~~, R H]]~~	+	[[Category: Yu RH]]
-	~~[[Category: Ion transport]]~~	+
-	~~[[Category: Iron acquisition]]~~	+
-	~~[[Category: Receptor]]~~	+
-	~~[[Category: Transferrin]]~~	+
-	~~[[Category: Transport protein]]~~	+
-	~~[[Category: Vaccine~~]]	+

OCA at 12:54, 23 March 2022

2022-03-23T12:54:32Z

←Older revision		Revision as of 12:54, 23 March 2022
Line 1:		Line 1:

	==Crystal Structure of Surface Lipoprotein==		==Crystal Structure of Surface Lipoprotein==
-	<StructureSection load='3hoe' size='340' side='right' caption='[[3hoe]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='3hoe' size='340' side='right'caption='[[3hoe]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hoe]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Actpl Actpl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3HOE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hoe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Actpl Actpl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HOE FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hol\|3hol]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hol\|3hol]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tbpB ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=715 ACTPL])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tbpB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=715 ACTPL])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3hoe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hoe OCA], [~~http~~://pdbe.org/3hoe PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3hoe RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3hoe PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3hoe ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hoe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hoe OCA], [https://pdbe.org/3hoe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hoe RCSB], [https://www.ebi.ac.uk/pdbsum/3hoe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hoe ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Actpl]]		[[Category: Actpl]]
		+	[[Category: Large Structures]]
	[[Category: Moraes, T F]]		[[Category: Moraes, T F]]
	[[Category: Schryvers, A B]]		[[Category: Schryvers, A B]]

OCA at 07:58, 12 December 2018

2018-12-12T07:58:53Z

←Older revision		Revision as of 07:58, 12 December 2018
Line 1:		Line 1:
		+
	==Crystal Structure of Surface Lipoprotein==		==Crystal Structure of Surface Lipoprotein==
	<StructureSection load='3hoe' size='340' side='right' caption='[[3hoe]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3hoe' size='340' side='right' caption='[[3hoe]], [[Resolution\|resolution]] 2.30Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hol\|3hol]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hol\|3hol]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tbpB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=715 ACTPL])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tbpB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=715 ACTPL])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hoe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hoe OCA], [http://pdbe.org/3hoe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hoe RCSB], [http://www.ebi.ac.uk/pdbsum/3hoe PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hoe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hoe OCA], [http://pdbe.org/3hoe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hoe RCSB], [http://www.ebi.ac.uk/pdbsum/3hoe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hoe ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/3hoe_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/3hoe_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 26:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 3hoe" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3hoe" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Transferrin-binding protein\|Transferrin-binding protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 23:49, 9 February 2016

2016-02-09T23:49:34Z

←Older revision		Revision as of 23:49, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3hoe' size='340' side='right' caption='[[3hoe]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3hoe' size='340' side='right' caption='[[3hoe]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hoe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Actinobacillus_pleuropneumoniae Actinobacillus pleuropneumoniae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HOE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hoe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Actpl Actpl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HOE FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hol\|3hol]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hol\|3hol]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tbpB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=715 ~~Actinobacillus pleuropneumoniae~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tbpB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=715 ACTPL])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hoe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hoe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hoe RCSB], [http://www.ebi.ac.uk/pdbsum/3hoe PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hoe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hoe OCA], [http://pdbe.org/3hoe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hoe RCSB], [http://www.ebi.ac.uk/pdbsum/3hoe PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hoe ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3hoe" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Actinobacillus pleuropneumoniae~~]]	+	[[Category: Actpl]]
	[[Category: Moraes, T F]]		[[Category: Moraes, T F]]
	[[Category: Schryvers, A B]]		[[Category: Schryvers, A B]]

OCA at 09:12, 8 December 2014

2014-12-08T09:12:15Z

←Older revision		Revision as of 09:12, 8 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3hoe.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of Surface Lipoprotein==
		+	<StructureSection load='3hoe' size='340' side='right' caption='[[3hoe]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3hoe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinobacillus_pleuropneumoniae Actinobacillus pleuropneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HOE FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hol\|3hol]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tbpB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=715 Actinobacillus pleuropneumoniae])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hoe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hoe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hoe RCSB], [http://www.ebi.ac.uk/pdbsum/3hoe PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/3hoe_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Pathogenic bacteria from the Neisseriaceae and Pasteurellacea families acquire iron directly from the host iron-binding glycoprotein, transferrin (Tf), in a process mediated by surface receptor proteins that directly bind host Tf, extract the iron, and transport it across the outer membrane. The bacterial Tf receptor is comprised of a surface exposed lipoprotein, Tf-binding protein B (TbpB), and an integral outer-membrane protein, Tf-binding protein A (TbpA), both of which are essential for survival in the host. In this study, we report the 1.98 A resolution structure of TbpB from the porcine pathogen Actinobacillus pleuropneumoniae, providing insights into the mechanism of Tf binding and the role of TbpB. A model for the complex of TbpB bound to Tf is proposed. Mutation of a single surface-exposed Phe residue on TbpB within the predicted interface completely abolishes binding to Tf, suggesting that the TbpB N lobe comprises the sole high-affinity binding region for Tf.

-	~~{{STRUCTURE_3hoe\| PDB=3hoe \| SCENE= }}~~	+	Insights into the bacterial transferrin receptor: the structure of transferrin-binding protein B from Actinobacillus pleuropneumoniae.,Moraes TF, Yu RH, Strynadka NC, Schryvers AB Mol Cell. 2009 Aug 28;35(4):523-33. PMID:19716795<ref>PMID:19716795</ref>

-	~~===Crystal Structure~~ of ~~Surface Lipoprotein===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19716795}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3hoe]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Actinobacillus_pleuropneumoniae Actinobacillus pleuropneumoniae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019716795<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Actinobacillus pleuropneumoniae]]		[[Category: Actinobacillus pleuropneumoniae]]
-	[[Category: Moraes, T F.]]	+	[[Category: Moraes, T F]]
-	[[Category: Schryvers, A B.]]	+	[[Category: Schryvers, A B]]
-	[[Category: Strynadka, N C.J.]]	+	[[Category: Strynadka, N C.J]]
-	[[Category: Yu, R H.]]	+	[[Category: Yu, R H]]
	[[Category: Ion transport]]		[[Category: Ion transport]]
	[[Category: Iron acquisition]]		[[Category: Iron acquisition]]

OCA: Protected "3hoe" [edit=sysop:move=sysop]

2013-03-06T15:06:14Z

Protected "3hoe" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:06, 6 March 2013

OCA at 15:06, 6 March 2013

2013-03-06T15:06:11Z

←Older revision		Revision as of 15:06, 6 March 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3hoe.png\|left\|200px]]		[[Image:3hoe.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3hoe", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3hoe\| PDB=3hoe \| SCENE= }}		{{STRUCTURE_3hoe\| PDB=3hoe \| SCENE= }}

	===Crystal Structure of Surface Lipoprotein===		===Crystal Structure of Surface Lipoprotein===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19716795}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19716795 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19716795}}		{{ABSTRACT_PUBMED_19716795}}

	==About this Structure==		==About this Structure==
-	~~3HOE~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Actinobacillus_pleuropneumoniae Actinobacillus pleuropneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA].	+	[[3hoe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinobacillus_pleuropneumoniae Actinobacillus pleuropneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19716795~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019716795</ref><references group="xtra"/>
	[[Category: Actinobacillus pleuropneumoniae]]		[[Category: Actinobacillus pleuropneumoniae]]
	[[Category: Moraes, T F.]]		[[Category: Moraes, T F.]]
Line 35:		Line 23:
	[[Category: Transport protein]]		[[Category: Transport protein]]
	[[Category: Vaccine]]		[[Category: Vaccine]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 15:09:44 2010''

OCA at 13:09, 28 January 2010

2010-01-28T13:09:45Z

←Older revision		Revision as of 13:09, 28 January 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3hoe.~~jpg~~\|left\|200px]]	+	[[Image:3hoe.png\|left\|200px]]

	<!--		<!--
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	3HOE is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Actinobacillus_pleuropneumoniae Actinobacillus pleuropneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA].	+	3HOE is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Actinobacillus_pleuropneumoniae Actinobacillus pleuropneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA].

	==Reference==		==Reference==
Line 36:		Line 36:
	[[Category: Vaccine]]		[[Category: Vaccine]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Oct 7 14~~:04:~~21 2009~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 15:09:44 2010''

OCA at 12:04, 7 October 2009

2009-10-07T12:04:23Z

←Older revision		Revision as of 12:04, 7 October 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3hoe.jpg\|left\|200px]]

-	The ~~entry 3hoe~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3hoe", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3hoe\| PDB=3hoe \| SCENE= }}

-	~~Authors: Moraes, T.F., Yu, R.H., Schryvers, A.B., Strynadka, N.C.J.~~	+	===Crystal Structure of Surface Lipoprotein===

-	Description: Crystal Structure of Surface Lipoprotein (CASP Target)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jul~~ ~~1 08~~:56:14 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19716795}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19716795 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19716795}}
		+
		+	==About this Structure==
		+	3HOE is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Actinobacillus_pleuropneumoniae Actinobacillus pleuropneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOE OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19716795</ref><references group="xtra"/>
		+	[[Category: Actinobacillus pleuropneumoniae]]
		+	[[Category: Moraes, T F.]]
		+	[[Category: Schryvers, A B.]]
		+	[[Category: Strynadka, N C.J.]]
		+	[[Category: Yu, R H.]]
		+	[[Category: Ion transport]]
		+	[[Category: Iron acquisition]]
		+	[[Category: Receptor]]
		+	[[Category: Transferrin]]
		+	[[Category: Transport protein]]
		+	[[Category: Vaccine]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 14:04:21 2009''

OCA at 05:56, 1 July 2009

2009-07-01T05:56:15Z

←Older revision		Revision as of 05:56, 1 July 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3hoe is ON HOLD	+	The entry 3hoe is ON HOLD until Paper Publication

	Authors: Moraes, T.F., Yu, R.H., Schryvers, A.B., Strynadka, N.C.J.		Authors: Moraes, T.F., Yu, R.H., Schryvers, A.B., Strynadka, N.C.J.
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	Description: Crystal Structure of Surface Lipoprotein (CASP Target)		Description: Crystal Structure of Surface Lipoprotein (CASP Target)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 10 18~~:00:32 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 1 08:56:14 2009''