3hw3 - Revision history

OCA at 15:54, 1 November 2023

2023-11-01T15:54:21Z

←Older revision		Revision as of 15:54, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3hw3' size='340' side='right'caption='[[3hw3]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3hw3' size='340' side='right'caption='[[3hw3]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hw3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~I96a0 I96a0~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HW3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hw3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/goose/Guangdong/1/1996(H5N1)) Influenza A virus (A/goose/Guangdong/1/1996(H5N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HW3 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~, ~~<scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3hw4\|3hw4]], [[3hw5\|3hw5]], [[3hw6\|3hw6]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">PA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93838 I96A0])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hw3 OCA], [https://pdbe.org/3hw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hw3 RCSB], [https://www.ebi.ac.uk/pdbsum/3hw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hw3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hw3 OCA], [https://pdbe.org/3hw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hw3 RCSB], [https://www.ebi.ac.uk/pdbsum/3hw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hw3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PA_I96A0 PA_I96A0]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication (By similarity).	+	[https://www.uniprot.org/uniprot/PA_I96A0 PA_I96A0] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: I96a0]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chen, Y]]	+	[[Category: Chen Y]]
-	[[Category: Guo, Y]]	+	[[Category: Guo Y]]
-	[[Category: Lou, Z]]	+	[[Category: Lou Z]]
-	[[Category: Ma, M]]	+	[[Category: Ma M]]
-	[[Category: Rao, Z]]	+	[[Category: Rao Z]]
-	[[Category: Zhao, C]]	+	[[Category: Zhao C]]
-	~~[[Category: Avian influenza virus]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Pa_n]]~~	+
-	~~[[Category: Phosphoprotein]]~~	+
-	~~[[Category: Ump~~]]	+

OCA at 11:58, 30 March 2022

2022-03-30T11:58:53Z

←Older revision		Revision as of 11:58, 30 March 2022
Line 1:		Line 1:

	==The crystal structure of avian influenza virus PA_N in complex with UMP==		==The crystal structure of avian influenza virus PA_N in complex with UMP==
-	<StructureSection load='3hw3' size='340' side='right' caption='[[3hw3]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='3hw3' size='340' side='right'caption='[[3hw3]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hw3]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/I96a0 I96a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3HW3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hw3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/I96a0 I96a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HW3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw4\|3hw4]], [[3hw5\|3hw5]], [[3hw6\|3hw6]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hw4\|3hw4]], [[3hw5\|3hw5]], [[3hw6\|3hw6]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93838 I96A0])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93838 I96A0])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3hw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hw3 OCA], [~~http~~://pdbe.org/3hw3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3hw3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3hw3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3hw3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hw3 OCA], [https://pdbe.org/3hw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hw3 RCSB], [https://www.ebi.ac.uk/pdbsum/3hw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hw3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PA_I96A0 PA_I96A0]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication (By similarity).	+	[[https://www.uniprot.org/uniprot/PA_I96A0 PA_I96A0]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:

	==See Also==		==See Also==
-	*[[RNA polymerase\|RNA polymerase]]	+	*[[RNA polymerase 3D structures\|RNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: I96a0]]		[[Category: I96a0]]
		+	[[Category: Large Structures]]
	[[Category: Chen, Y]]		[[Category: Chen, Y]]
	[[Category: Guo, Y]]		[[Category: Guo, Y]]

OCA at 06:12, 5 August 2016

2016-08-05T06:12:41Z

←Older revision		Revision as of 06:12, 5 August 2016
Line 1:		Line 1:
		+
	==The crystal structure of avian influenza virus PA_N in complex with UMP==		==The crystal structure of avian influenza virus PA_N in complex with UMP==
	<StructureSection load='3hw3' size='340' side='right' caption='[[3hw3]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3hw3' size='340' side='right' caption='[[3hw3]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hw3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Influenza_a_virus_(a/goose/guangdong/1/96(h5n1)) Influenza a virus (a/goose/guangdong/1/96(h5n1))~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HW3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hw3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/I96a0 I96a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HW3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw4\|3hw4]], [[3hw5\|3hw5]], [[3hw6\|3hw6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw4\|3hw4]], [[3hw5\|3hw5]], [[3hw6\|3hw6]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93838 ~~Influenza A virus (A/Goose/Guangdong/1/96(H5N1))~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93838 I96A0])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hw3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hw3 RCSB], [http://www.ebi.ac.uk/pdbsum/3hw3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hw3 OCA], [http://pdbe.org/3hw3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hw3 RCSB], [http://www.ebi.ac.uk/pdbsum/3hw3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hw3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3hw3" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 25:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: I96a0]]
	[[Category: Chen, Y]]		[[Category: Chen, Y]]
	[[Category: Guo, Y]]		[[Category: Guo, Y]]

OCA at 23:43, 24 December 2014

2014-12-24T23:43:35Z

←Older revision		Revision as of 23:43, 24 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hw3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hw3 RCSB], [http://www.ebi.ac.uk/pdbsum/3hw3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hw3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hw3 RCSB], [http://www.ebi.ac.uk/pdbsum/3hw3 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PA_I96A0 PA_I96A0]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 09:27, 8 December 2014

2014-12-08T09:27:36Z

←Older revision		Revision as of 09:27, 8 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3hw3.~~png~~\|~~left~~\|~~200px~~]]	+	==The crystal structure of avian influenza virus PA_N in complex with UMP==
		+	<StructureSection load='3hw3' size='340' side='right' caption='[[3hw3]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3hw3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus_(a/goose/guangdong/1/96(h5n1)) Influenza a virus (a/goose/guangdong/1/96(h5n1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HW3 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw4\|3hw4]], [[3hw5\|3hw5]], [[3hw6\|3hw6]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93838 Influenza A virus (A/Goose/Guangdong/1/96(H5N1))])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hw3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hw3 RCSB], [http://www.ebi.ac.uk/pdbsum/3hw3 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Highly pathogenic influenza virus strains currently in circulation pose a significant risk of a global pandemic. Following the reported crystal structure of the endonuclease domain from the avian influenza virus polymerase PA subunit, here we report the results of a systematic X-ray crystallographic analysis of its complex with adenosine, uridine, and thymidine nucleoside monophosphates (NMPs). Electron density corresponding to the monophosphate moiety of each nucleotide was apparent in each NMP complex and bound to the catalytic metal. A hydrophobic site was found to contribute to nucleoside binding. The NMP complex structures should represent the conformation of the bound product after nuclease cleavage. Moreover, one solvent molecule was found to occupy an equivalent position to the second reported Mn(2+) ion, where it mediates the interaction between bound NMPs and the N-terminal PA domain in the presence of the Mg(2+) ion. The results presented here indicate a possible cleavage mechanism and identify a distinct nucleotide binding pocket. The identification of this binding pocket opens a new avenue for anti-influenza drug discovery, targeting the cap-dependent endonuclease, in response to the worldwide threat of influenza.

-	~~{{STRUCTURE_3hw3\| PDB=3hw3 \| SCENE= }}~~	+	Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center.,Zhao C, Lou Z, Guo Y, Ma M, Chen Y, Liang S, Zhang L, Chen S, Li X, Liu Y, Bartlam M, Rao Z J Virol. 2009 Sep;83(18):9024-30. Epub 2009 Jul 8. PMID:19587036<ref>PMID:19587036</ref>

-	~~===The crystal structure of avian influenza virus PA_N in complex with UMP===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19587036}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3hw3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki~~/~~Influenza_a_virus_(~~a~~/goose/guangdong/1/96(h5n1)) Influenza a virus (a/goose/guangdong/1/96(h5n1))]~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3HW3 OCA].~~	+

	==See Also==		==See Also==
-	*[[Polymerase acidic protein\|Polymerase acidic protein]]
	*[[RNA polymerase\|RNA polymerase]]		*[[RNA polymerase\|RNA polymerase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019587036<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
-	[[Category: Chen, Y.]]	+	</StructureSection>
-	[[Category: Guo, Y.]]	+	[[Category: Chen, Y]]
-	[[Category: Lou, Z.]]	+	[[Category: Guo, Y]]
-	[[Category: Ma, M.]]	+	[[Category: Lou, Z]]
-	[[Category: Rao, Z.]]	+	[[Category: Ma, M]]
-	[[Category: Zhao, C.]]	+	[[Category: Rao, Z]]
		+	[[Category: Zhao, C]]
	[[Category: Avian influenza virus]]		[[Category: Avian influenza virus]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 10:20, 20 October 2012

2012-10-20T10:20:24Z

←Older revision		Revision as of 10:20, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3hw3]] is a 4 chain structure ~~of [[Polymerase acidic protein]] and [[RNA polymerase]]~~ with sequence from [http://en.wikipedia.org/wiki/~~Viruses Viruses~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA].	+	[[3hw3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus_(a/goose/guangdong/1/96(h5n1)) Influenza a virus (a/goose/guangdong/1/96(h5n1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA].

	==See Also==		==See Also==
Line 16:		Line 16:
	==Reference==		==Reference==
	<ref group="xtra">PMID:019587036</ref><references group="xtra"/>		<ref group="xtra">PMID:019587036</ref><references group="xtra"/>
-	[[Category: Viruses]]
	[[Category: Chen, Y.]]		[[Category: Chen, Y.]]
	[[Category: Guo, Y.]]		[[Category: Guo, Y.]]

OCA: Protected "3hw3" [edit=sysop:move=sysop]

2012-07-26T01:46:49Z

Protected "3hw3" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:46, 26 July 2012

OCA at 01:46, 26 July 2012

2012-07-26T01:46:47Z

←Older revision		Revision as of 01:46, 26 July 2012
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3hw3.png\|left\|200px]]
-	[[Image:3hw3.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3hw3", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3hw3\| PDB=3hw3 \| SCENE= }}		{{STRUCTURE_3hw3\| PDB=3hw3 \| SCENE= }}

	===The crystal structure of avian influenza virus PA_N in complex with UMP===		===The crystal structure of avian influenza virus PA_N in complex with UMP===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19587036}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19587036 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19587036}}		{{ABSTRACT_PUBMED_19587036}}

	==About this Structure==		==About this Structure==
-	~~3HW3~~ is a 4 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA].	+	[[3hw3]] is a 4 chain structure of [[Polymerase acidic protein]] and [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA].
		+
		+	==See Also==
		+	*[[Polymerase acidic protein\|Polymerase acidic protein]]
		+	*[[RNA polymerase\|RNA polymerase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19587036~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019587036</ref><references group="xtra"/>
	[[Category: Viruses]]		[[Category: Viruses]]
	[[Category: Chen, Y.]]		[[Category: Chen, Y.]]
Line 32:		Line 24:
	[[Category: Zhao, C.]]		[[Category: Zhao, C.]]
	[[Category: Avian influenza virus]]		[[Category: Avian influenza virus]]
-	[[Category: Crystal structure]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Pa_n]]		[[Category: Pa_n]]
	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
	[[Category: Ump]]		[[Category: Ump]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:27:44 2009''

OCA at 08:27, 14 October 2009

2009-10-14T08:27:46Z

←Older revision		Revision as of 08:27, 14 October 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3hw3.jpg\|left\|200px]]

-	The ~~entry 3hw3~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3hw3", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3hw3\| PDB=3hw3 \| SCENE= }}

-	~~Authors: Zhao, C., Lou, Z., Guo, Y., Ma, M., Chen, Y., Rao, Z.~~	+	===The crystal structure of avian influenza virus PA_N in complex with UMP===

-	Description: The crystal structure of avian influenza virus PA_N in complex with UMP

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Aug 5 09~~:45:56 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19587036}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19587036 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19587036}}
		+
		+	==About this Structure==
		+	3HW3 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HW3 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19587036</ref><references group="xtra"/>
		+	[[Category: Viruses]]
		+	[[Category: Chen, Y.]]
		+	[[Category: Guo, Y.]]
		+	[[Category: Lou, Z.]]
		+	[[Category: Ma, M.]]
		+	[[Category: Rao, Z.]]
		+	[[Category: Zhao, C.]]
		+	[[Category: Avian influenza virus]]
		+	[[Category: Crystal structure]]
		+	[[Category: Hydrolase]]
		+	[[Category: Pa_n]]
		+	[[Category: Phosphoprotein]]
		+	[[Category: Ump]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:27:44 2009''

OCA at 06:45, 5 August 2009

2009-08-05T06:45:57Z

←Older revision		Revision as of 06:45, 5 August 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3hw3 is ON HOLD	+	The entry 3hw3 is ON HOLD until Paper Publication

	Authors: Zhao, C., Lou, Z., Guo, Y., Ma, M., Chen, Y., Rao, Z.		Authors: Zhao, C., Lou, Z., Guo, Y., Ma, M., Chen, Y., Rao, Z.
Line 7:		Line 7:
	Description: The crystal structure of avian influenza virus PA_N in complex with UMP		Description: The crystal structure of avian influenza virus PA_N in complex with UMP

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jul 15 08~~:28:37 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 5 09:45:56 2009''