3ihj - Revision history

OCA at 07:47, 6 September 2023

2023-09-06T07:47:51Z

←Older revision		Revision as of 07:47, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3ihj' size='340' side='right'caption='[[3ihj]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3ihj' size='340' side='right'caption='[[3ihj]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ihj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IHJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ihj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IHJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=PLP:PYRIDOXAL~~-~~5-PHOSPHATE'>PLP</scene>~~, ~~<scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>GPT2, AAT2, ALT2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~9606 HUMAN])</td~~><~~/tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Alanine_transaminase Alanine transaminase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.2 2.6.1.2]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [https://pdbe.org/3ihj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [https://www.ebi.ac.uk/pdbsum/3ihj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ihj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [https://pdbe.org/3ihj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [https://www.ebi.ac.uk/pdbsum/3ihj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ihj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ALAT2_HUMAN ALAT2_HUMAN]] Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.<ref>PMID:11863375</ref>	+	[https://www.uniprot.org/uniprot/ALAT2_HUMAN ALAT2_HUMAN] Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.<ref>PMID:11863375</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Alanine transaminase]]~~	+	[[Category: Homo sapiens]]
-	~~[[Category: Human~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arrowsmith~~, C H]]~~	+	[[Category: Arrowsmith CH]]
-	~~[[Category: Berg, S Van Den~~]]	+	[[Category: Berglund H]]
-	[[Category: Berglund, H]]	+	[[Category: Bountra C]]
-	[[Category: Bountra, C]]	+	[[Category: Collins R]]
-	[[Category: Collins, R]]	+	[[Category: Edwards AM]]
-	[[Category: Edwards~~, A M~~]]	+	[[Category: Flodin S]]
-	[[Category: Flodin, S]]	+	[[Category: Flores A]]
-	[[Category: Flores, A]]	+	[[Category: Graslund S]]
-	[[Category: Graslund, S]]	+	[[Category: Hammarstrom M]]
-	[[Category: Hammarstrom, M]]	+	[[Category: Johansson A]]
-	[[Category: Johansson, A]]	+	[[Category: Johansson I]]
-	[[Category: Johansson, I]]	+	[[Category: Karlberg T]]
-	[[Category: Karlberg, T]]	+	[[Category: Kotenyova T]]
-	[[Category: Kotenyova, T]]	+	[[Category: Kotzsch A]]
-	[[Category: Kotzsch, A]]	+	[[Category: Moche M]]
-	[[Category: Moche, M]]	+	[[Category: Nielsen TK]]
-	[[Category: Nielsen~~, T K~~]]	+	[[Category: Nordlund P]]
-	[[Category: Nordlund, P]]	+	[[Category: Nyman T]]
-	[[Category: Nyman, T]]	+	[[Category: Persson C]]
-	[[Category: Persson, C]]	+	[[Category: Roos AK]]
-	[[Category: Roos~~, A K]]~~	+	[[Category: Schuler H]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Schutz P]]
-	[[Category: Schuler, H]]	+	[[Category: Siponen MI]]
-	[[Category: Schutz, P]]	+	[[Category: Svensson L]]
-	[[Category: Siponen~~, M I~~]]	+	[[Category: Thorsell AG]]
-	[[Category: Svensson, L]]	+	[[Category: Tresaugues L]]
-	[[Category: Thorsell~~, A G~~]]	+	[[Category: Van Den Berg S]]
-	[[Category: Tresaugues, L]]	+	[[Category: Weigelt J]]
-	[[Category: ~~Weigelt, J~~]]	+	[[Category: Welin M]]
-	[[Category: ~~Welin, M~~]]	+	[[Category: Wisniewska M]]
-	[[Category: ~~Wisniewska,~~ M]]	+
-	[[Category: ~~Aminotransferase]]~~	+
-	~~[[Category: Helix]]~~	+
-	~~[[Category: Pyridoxal phosphate]]~~	+
-	~~[[Category: Sgc]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 03:32, 21 April 2022

2022-04-21T03:32:49Z

←Older revision		Revision as of 03:32, 21 April 2022
Line 1:		Line 1:

	==Human alanine aminotransferase 2 in complex with PLP==		==Human alanine aminotransferase 2 in complex with PLP==
-	<StructureSection load='3ihj' size='340' side='right' caption='[[3ihj]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='3ihj' size='340' side='right'caption='[[3ihj]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ihj]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3IHJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ihj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IHJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GPT2, AAT2, ALT2 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GPT2, AAT2, ALT2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Alanine_transaminase Alanine transaminase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.2 2.6.1.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alanine_transaminase Alanine transaminase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.2 2.6.1.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [~~http~~://pdbe.org/3ihj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ihj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ihj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [https://pdbe.org/3ihj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [https://www.ebi.ac.uk/pdbsum/3ihj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ihj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ALAT2_HUMAN ALAT2_HUMAN]] Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.<ref>PMID:11863375</ref>	+	[[https://www.uniprot.org/uniprot/ALAT2_HUMAN ALAT2_HUMAN]] Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.<ref>PMID:11863375</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 23:

	==See Also==		==See Also==
-	*[[Aminotransferase\|Aminotransferase]]	+	*[[Aminotransferase 3D structures\|Aminotransferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 30:		Line 30:
	[[Category: Alanine transaminase]]		[[Category: Alanine transaminase]]
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Berg, S Van Den]]		[[Category: Berg, S Van Den]]

OCA at 09:50, 19 December 2018

2018-12-19T09:50:36Z

←Older revision		Revision as of 09:50, 19 December 2018
Line 1:		Line 1:
		+
	==Human alanine aminotransferase 2 in complex with PLP==		==Human alanine aminotransferase 2 in complex with PLP==
	<StructureSection load='3ihj' size='340' side='right' caption='[[3ihj]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3ihj' size='340' side='right' caption='[[3ihj]], [[Resolution\|resolution]] 2.30Å' scene=''>
Line 6:		Line 7:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GPT2, AAT2, ALT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GPT2, AAT2, ALT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine_transaminase Alanine transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.2 2.6.1.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine_transaminase Alanine transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.2 2.6.1.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [http://pdbe.org/3ihj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [http://www.ebi.ac.uk/pdbsum/3ihj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [http://pdbe.org/3ihj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [http://www.ebi.ac.uk/pdbsum/3ihj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ihj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/3ihj_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/3ihj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 17:15, 9 February 2016

2016-02-09T17:15:35Z

←Older revision		Revision as of 17:15, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3ihj' size='340' side='right' caption='[[3ihj]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3ihj' size='340' side='right' caption='[[3ihj]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ihj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IHJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ihj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IHJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GPT2, AAT2, ALT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GPT2, AAT2, ALT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine_transaminase Alanine transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.2 2.6.1.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine_transaminase Alanine transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.2 2.6.1.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [http://www.ebi.ac.uk/pdbsum/3ihj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [http://pdbe.org/3ihj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [http://www.ebi.ac.uk/pdbsum/3ihj PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ihj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+
		+	==See Also==
		+	*[[Aminotransferase\|Aminotransferase]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Alanine transaminase]]		[[Category: Alanine transaminase]]
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Berg, S Van Den]]		[[Category: Berg, S Van Den]]

OCA at 08:18, 25 December 2014

2014-12-25T08:18:35Z

←Older revision		Revision as of 08:18, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [http://www.ebi.ac.uk/pdbsum/3ihj PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [http://www.ebi.ac.uk/pdbsum/3ihj PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ALAT2_HUMAN ALAT2_HUMAN]] Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.<ref>PMID:11863375</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:07, 18 December 2014

2014-12-18T06:07:38Z

←Older revision		Revision as of 06:07, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3ihj\| PDB=3ihj \| SCENE= }}~~	+	==Human alanine aminotransferase 2 in complex with PLP==
-	===Human alanine aminotransferase 2 in complex with PLP===	+	<StructureSection load='3ihj' size='340' side='right' caption='[[3ihj]], [[Resolution\|resolution]] 2.30Å' scene=''>
-		+	== Structural highlights ==
-	==~~About this Structure~~==	+	<table><tr><td colspan='2'>[[3ihj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IHJ FirstGlance]. <br>
-	[[3ihj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA].	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GPT2, AAT2, ALT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine_transaminase Alanine transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.2 2.6.1.2] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ihj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ihj RCSB], [http://www.ebi.ac.uk/pdbsum/3ihj PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/3ihj_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	__TOC__
		+	</StructureSection>
	[[Category: Alanine transaminase]]		[[Category: Alanine transaminase]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Arrowsmith, C H.]]	+	[[Category: Arrowsmith, C H]]
-	[[Category: Berg, S Van Den.]]	+	[[Category: Berg, S Van Den]]
-	[[Category: Berglund, H.]]	+	[[Category: Berglund, H]]
-	[[Category: Bountra, C.]]	+	[[Category: Bountra, C]]
-	[[Category: Collins, R.]]	+	[[Category: Collins, R]]
-	[[Category: Edwards, A M.]]	+	[[Category: Edwards, A M]]
-	[[Category: Flodin, S.]]	+	[[Category: Flodin, S]]
-	[[Category: Flores, A.]]	+	[[Category: Flores, A]]
-	[[Category: Graslund, S.]]	+	[[Category: Graslund, S]]
-	[[Category: Hammarstrom, M.]]	+	[[Category: Hammarstrom, M]]
-	[[Category: Johansson, A.]]	+	[[Category: Johansson, A]]
-	[[Category: Johansson, I.]]	+	[[Category: Johansson, I]]
-	[[Category: Karlberg, T.]]	+	[[Category: Karlberg, T]]
-	[[Category: Kotenyova, T.]]	+	[[Category: Kotenyova, T]]
-	[[Category: Kotzsch, A.]]	+	[[Category: Kotzsch, A]]
-	[[Category: Moche, M.]]	+	[[Category: Moche, M]]
-	[[Category: Nielsen, T K.]]	+	[[Category: Nielsen, T K]]
-	[[Category: Nordlund, P.]]	+	[[Category: Nordlund, P]]
-	[[Category: Nyman, T.]]	+	[[Category: Nyman, T]]
-	[[Category: Persson, C.]]	+	[[Category: Persson, C]]
-	[[Category: Roos, A K.]]	+	[[Category: Roos, A K]]
-	[[Category: ~~SGC,~~ Structural ~~Genomics Consortium.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Schuler, H.]]	+	[[Category: Schuler, H]]
-	[[Category: Schutz, P.]]	+	[[Category: Schutz, P]]
-	[[Category: Siponen, M I.]]	+	[[Category: Siponen, M I]]
-	[[Category: Svensson, L.]]	+	[[Category: Svensson, L]]
-	[[Category: Thorsell, A G.]]	+	[[Category: Thorsell, A G]]
-	[[Category: Tresaugues, L.]]	+	[[Category: Tresaugues, L]]
-	[[Category: Weigelt, J.]]	+	[[Category: Weigelt, J]]
-	[[Category: Welin, M.]]	+	[[Category: Welin, M]]
-	[[Category: Wisniewska, M.]]	+	[[Category: Wisniewska, M]]
	[[Category: Aminotransferase]]		[[Category: Aminotransferase]]
	[[Category: Helix]]		[[Category: Helix]]
	[[Category: Pyridoxal phosphate]]		[[Category: Pyridoxal phosphate]]
	[[Category: Sgc]]		[[Category: Sgc]]
-	[[Category: Structural genomic]]
-	[[Category: Structural genomics consortium]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA: Protected "3ihj" [edit=sysop:move=sysop]

2013-03-13T10:43:46Z

Protected "3ihj" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:43, 13 March 2013

OCA at 10:43, 13 March 2013

2013-03-13T10:43:44Z

←Older revision		Revision as of 10:43, 13 March 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3ihj.jpg\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ihj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ihj\| PDB=3ihj \| SCENE= }}		{{STRUCTURE_3ihj\| PDB=3ihj \| SCENE= }}
-
	===Human alanine aminotransferase 2 in complex with PLP===		===Human alanine aminotransferase 2 in complex with PLP===
-

	==About this Structure==		==About this Structure==
-	~~3IHJ~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA].	+	[[3ihj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA].
	[[Category: Alanine transaminase]]		[[Category: Alanine transaminase]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
Line 48:		Line 37:
	[[Category: Welin, M.]]		[[Category: Welin, M.]]
	[[Category: Wisniewska, M.]]		[[Category: Wisniewska, M.]]
-	[[Category: Alternative splicing]]
	[[Category: Aminotransferase]]		[[Category: Aminotransferase]]
	[[Category: Helix]]		[[Category: Helix]]
Line 56:		Line 44:
	[[Category: Structural genomics consortium]]		[[Category: Structural genomics consortium]]
	[[Category: Transferase]]		[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 13:43:52 2009''

OCA at 10:43, 19 August 2009

2009-08-19T10:43:55Z

←Older revision		Revision as of 10:43, 19 August 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3ihj.jpg\|left\|200px]]

-	The ~~entry 3ihj~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3ihj", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3ihj\| PDB=3ihj \| SCENE= }}

-	Authors: Wisniewska, M., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Kotzsch, A., Moche, M., Nielsen, T.K.	+	===Human alanine aminotransferase 2 in complex with PLP===

-	Description: Human glutamate pyruvate transaminase 2

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug ~~12 12~~:25:42 2009''	+	==About this Structure==
		+	3IHJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHJ OCA].
		+	[[Category: Alanine transaminase]]
		+	[[Category: Homo sapiens]]
		+	[[Category: Arrowsmith, C H.]]
		+	[[Category: Berg, S Van Den.]]
		+	[[Category: Berglund, H.]]
		+	[[Category: Bountra, C.]]
		+	[[Category: Collins, R.]]
		+	[[Category: Edwards, A M.]]
		+	[[Category: Flodin, S.]]
		+	[[Category: Flores, A.]]
		+	[[Category: Graslund, S.]]
		+	[[Category: Hammarstrom, M.]]
		+	[[Category: Johansson, A.]]
		+	[[Category: Johansson, I.]]
		+	[[Category: Karlberg, T.]]
		+	[[Category: Kotenyova, T.]]
		+	[[Category: Kotzsch, A.]]
		+	[[Category: Moche, M.]]
		+	[[Category: Nielsen, T K.]]
		+	[[Category: Nordlund, P.]]
		+	[[Category: Nyman, T.]]
		+	[[Category: Persson, C.]]
		+	[[Category: Roos, A K.]]
		+	[[Category: SGC, Structural Genomics Consortium.]]
		+	[[Category: Schuler, H.]]
		+	[[Category: Schutz, P.]]
		+	[[Category: Siponen, M I.]]
		+	[[Category: Svensson, L.]]
		+	[[Category: Thorsell, A G.]]
		+	[[Category: Tresaugues, L.]]
		+	[[Category: Weigelt, J.]]
		+	[[Category: Welin, M.]]
		+	[[Category: Wisniewska, M.]]
		+	[[Category: Alternative splicing]]
		+	[[Category: Aminotransferase]]
		+	[[Category: Helix]]
		+	[[Category: Pyridoxal phosphate]]
		+	[[Category: Sgc]]
		+	[[Category: Structural genomic]]
		+	[[Category: Structural genomics consortium]]
		+	[[Category: Transferase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 13:43:52 2009''

OCA at 09:25, 12 August 2009

2009-08-12T09:25:42Z

←Older revision		Revision as of 09:25, 12 August 2009
Line 3:		Line 3:
	The entry 3ihj is ON HOLD		The entry 3ihj is ON HOLD

-	Authors: Wisniewska, M., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T, Kotzsch, A, Moche, M., Nielsen, T.K.,	+	Authors: Wisniewska, M., Siponen, M.I., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Kotzsch, A., Moche, M., Nielsen, T.K.

	Description: Human glutamate pyruvate transaminase 2		Description: Human glutamate pyruvate transaminase 2

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug ~~5 09~~:53:07 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 12 12:25:42 2009''