3ina - Revision history

OCA at 16:01, 1 November 2023

2023-11-01T16:01:12Z

←Older revision		Revision as of 16:01, 1 November 2023
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	<StructureSection load='3ina' size='340' side='right'caption='[[3ina]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3ina' size='340' side='right'caption='[[3ina]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ina]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_thetaiotaomicron"_distaso_1912 "bacillus~~ thetaiotaomicron~~" distaso 1912~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3INA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ina]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3INA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene>, <scene name='pdbligand=SUS:2-DEOXY-3,6-DI-O-SULFO-2-(SULFOAMINO)-ALPHA-D-GLUCOPYRANOSE'>SUS</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3imn\|3imn]], [[3in9\|3in9]]</div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene>, <scene name='pdbligand=SUS:2-DEOXY-3,6-DI-O-SULFO-2-(SULFOAMINO)-ALPHA-D-GLUCOPYRANOSE'>SUS</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ina FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ina OCA], [https://pdbe.org/3ina PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ina RCSB], [https://www.ebi.ac.uk/pdbsum/3ina PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ina ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ina FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ina OCA], [https://pdbe.org/3ina PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ina RCSB], [https://www.ebi.ac.uk/pdbsum/3ina PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ina ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q89YQ6_BACTN Q89YQ6_BACTN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ thetaiotaomicron ~~distaso 1912~~]]	+	[[Category: Bacteroides thetaiotaomicron]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Han~~, Y H~~]]	+	[[Category: Han YH]]
-	[[Category: Jeon~~, Y H~~]]	+	[[Category: Jeon YH]]
-	[[Category: Kim~~, H Y~~]]	+	[[Category: Kim HY]]
-	[[Category: Ryu~~, K S]]~~	+	[[Category: Ryu KS]]
-	~~[[Category: Jelly roll]]~~	+
-	~~[[Category: Lyase~~]]	+

OCA at 03:37, 21 April 2022

2022-04-21T03:37:04Z

←Older revision		Revision as of 03:37, 21 April 2022
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	<StructureSection load='3ina' size='340' side='right'caption='[[3ina]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3ina' size='340' side='right'caption='[[3ina]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ina]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_thetaiotaomicron"_distaso_1912 "bacillus thetaiotaomicron" distaso 1912]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3INA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ina]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_thetaiotaomicron"_distaso_1912 "bacillus thetaiotaomicron" distaso 1912]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3INA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene>, <scene name='pdbligand=SUS:2-DEOXY-3,6-DI-O-SULFO-2-(SULFOAMINO)-ALPHA-D-GLUCOPYRANOSE'>SUS</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene>, <scene name='pdbligand=SUS:2-DEOXY-3,6-DI-O-SULFO-2-(SULFOAMINO)-ALPHA-D-GLUCOPYRANOSE'>SUS</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3imn\|3imn]], [[3in9\|3in9]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3imn\|3imn]], [[3in9\|3in9]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ina FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ina OCA], [~~http~~://pdbe.org/3ina PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ina RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ina PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ina ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ina FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ina OCA], [https://pdbe.org/3ina PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ina RCSB], [https://www.ebi.ac.uk/pdbsum/3ina PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ina ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:16, 7 August 2019

2019-08-07T07:16:15Z

←Older revision		Revision as of 07:16, 7 August 2019
Line 1:		Line 1:

	==Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin==		==Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin==
-	<StructureSection load='3ina' size='340' side='right' caption='[[3ina]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='3ina' size='340' side='right'caption='[[3ina]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3ina]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_thetaiotaomicron"_distaso_1912 "bacillus thetaiotaomicron" distaso 1912]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3INA FirstGlance]. <br>		<table><tr><td colspan='2'>[[3ina]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_thetaiotaomicron"_distaso_1912 "bacillus thetaiotaomicron" distaso 1912]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3INA FirstGlance]. <br>
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus thetaiotaomicron distaso 1912]]		[[Category: Bacillus thetaiotaomicron distaso 1912]]
		+	[[Category: Large Structures]]
	[[Category: Han, Y H]]		[[Category: Han, Y H]]
	[[Category: Jeon, Y H]]		[[Category: Jeon, Y H]]

OCA at 08:10, 1 November 2017

2017-11-01T08:10:10Z

←Older revision		Revision as of 08:10, 1 November 2017
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3ina]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_thetaiotaomicron"_distaso_1912 "bacillus thetaiotaomicron" distaso 1912]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3INA FirstGlance]. <br>		<table><tr><td colspan='2'>[[3ina]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_thetaiotaomicron"_distaso_1912 "bacillus thetaiotaomicron" distaso 1912]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3INA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=~~SUS~~:2~~-DEOXY-3,6-DI~~-O-SULFO~~-2-(SULFOAMINO)~~-ALPHA-D-~~GLUCOPYRANOSE~~'>~~SUS~~</scene>, <scene name='pdbligand=~~IDS~~:2-O-~~SULFO-ALPHA-L-IDOPYRANURONIC+ACID~~'>~~IDS~~</scene>, <scene name='pdbligand=~~SGN~~:N,O6-~~DISULFO~~-~~GLUCOSAMINE~~'>~~SGN~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene>, <scene name='pdbligand=SUS:2-DEOXY-3,6-DI-O-SULFO-2-(SULFOAMINO)-ALPHA-D-GLUCOPYRANOSE'>SUS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3imn\|3imn]], [[3in9\|3in9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3imn\|3imn]], [[3in9\|3in9]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ina FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ina OCA], [http://pdbe.org/3ina PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ina RCSB], [http://www.ebi.ac.uk/pdbsum/3ina PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ina ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ina FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ina OCA], [http://pdbe.org/3ina PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ina RCSB], [http://www.ebi.ac.uk/pdbsum/3ina PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ina ProSAT]</span></td></tr>

OCA at 09:02, 5 August 2016

2016-08-05T09:02:45Z

←Older revision		Revision as of 09:02, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin==		==Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin==
	<StructureSection load='3ina' size='340' side='right' caption='[[3ina]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3ina' size='340' side='right' caption='[[3ina]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ina]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacteroides_thetaiotaomicron Bacteroides~~ thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3INA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ina]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_thetaiotaomicron"_distaso_1912 "bacillus thetaiotaomicron" distaso 1912]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3INA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SUS:2-DEOXY-3,6-DI-O-SULFO-2-(SULFOAMINO)-ALPHA-D-GLUCOPYRANOSE'>SUS</scene>, <scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SUS:2-DEOXY-3,6-DI-O-SULFO-2-(SULFOAMINO)-ALPHA-D-GLUCOPYRANOSE'>SUS</scene>, <scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3imn\|3imn]], [[3in9\|3in9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3imn\|3imn]], [[3in9\|3in9]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ina FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ina OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ina RCSB], [http://www.ebi.ac.uk/pdbsum/3ina PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ina FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ina OCA], [http://pdbe.org/3ina PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ina RCSB], [http://www.ebi.ac.uk/pdbsum/3ina PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ina ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ina" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacteroides~~ thetaiotaomicron]]	+	[[Category: Bacillus thetaiotaomicron distaso 1912]]
	[[Category: Han, Y H]]		[[Category: Han, Y H]]
	[[Category: Jeon, Y H]]		[[Category: Jeon, Y H]]

OCA at 06:33, 18 December 2014

2014-12-18T06:33:19Z

←Older revision		Revision as of 06:33, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3ina\| PDB=3ina \| SCENE= }}~~	+	==Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin==
-	===Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin===	+	<StructureSection load='3ina' size='340' side='right' caption='[[3ina]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~{{ABSTRACT_PUBMED_19801541}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ina]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3INA FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SUS:2-DEOXY-3,6-DI-O-SULFO-2-(SULFOAMINO)-ALPHA-D-GLUCOPYRANOSE'>SUS</scene>, <scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3imn\|3imn]], [[3in9\|3in9]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ina FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ina OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ina RCSB], [http://www.ebi.ac.uk/pdbsum/3ina PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Heparin lyase I (heparinase I) specifically depolymerizes heparin, cleaving the glycosidic linkage next to iduronic acid. Here, we show the crystal structures of heparinase I from Bacteroides thetaiotaomicron at various stages of the reaction with heparin oligosaccharides before and just after cleavage and product disaccharide. The heparinase I structure is comprised of a beta-jellyroll domain harboring a long and deep substrate binding groove and an unusual thumb-resembling extension. This thumb, decorated with many basic residues, is of particular importance in activity especially on short heparin oligosaccharides. Unexpected structural similarity of the active site to that of heparinase II with an (alpha/alpha)(6) fold is observed. Mutational studies and kinetic analysis of this enzyme provide insights into the catalytic mechanism, the substrate recognition, and processivity.

-	~~==About this Structure==~~	+	Structural snapshots of heparin depolymerization by heparin lyase I.,Han YH, Garron ML, Kim HY, Kim WS, Zhang Z, Ryu KS, Shaya D, Xiao Z, Cheong C, Kim YS, Linhardt RJ, Jeon YH, Cygler M J Biol Chem. 2009 Dec 4;284(49):34019-27. Epub 2009 Oct 2. PMID:19801541<ref>PMID:19801541</ref>
-	~~[[3ina]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3INA OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	<~~ref group="xtra">PMID:019801541<~~/~~ref~~><~~references group="xtra"~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Bacteroides thetaiotaomicron]]		[[Category: Bacteroides thetaiotaomicron]]
-	[[Category: Han, Y H.]]	+	[[Category: Han, Y H]]
-	[[Category: Jeon, Y H.]]	+	[[Category: Jeon, Y H]]
-	[[Category: Kim, H Y.]]	+	[[Category: Kim, H Y]]
-	[[Category: Ryu, K S.]]	+	[[Category: Ryu, K S]]
	[[Category: Jelly roll]]		[[Category: Jelly roll]]
	[[Category: Lyase]]		[[Category: Lyase]]

OCA: Protected "3ina" [edit=sysop:move=sysop]

2013-03-13T11:05:17Z

Protected "3ina" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:05, 13 March 2013

OCA at 11:05, 13 March 2013

2013-03-13T11:05:15Z

←Older revision		Revision as of 11:05, 13 March 2013
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-	{{Seed}}
-	[[Image:3ina.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ina", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ina\| PDB=3ina \| SCENE= }}		{{STRUCTURE_3ina\| PDB=3ina \| SCENE= }}
-
	===Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin===		===Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19801541}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19801541 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19801541}}		{{ABSTRACT_PUBMED_19801541}}

	==About this Structure==		==About this Structure==
-	~~3INA~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA].	+	[[3ina]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19801541~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019801541</ref><references group="xtra"/>
	[[Category: Bacteroides thetaiotaomicron]]		[[Category: Bacteroides thetaiotaomicron]]
	[[Category: Han, Y H.]]		[[Category: Han, Y H.]]
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	[[Category: Jelly roll]]		[[Category: Jelly roll]]
	[[Category: Lyase]]		[[Category: Lyase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 14:37:00 2009''

OCA at 12:37, 9 December 2009

2009-12-09T12:37:01Z

←Older revision		Revision as of 12:37, 9 December 2009
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	{{Seed}}		{{Seed}}
-	[[Image:3ina.~~jpg~~\|left\|200px]]	+	[[Image:3ina.png\|left\|200px]]

	<!--		<!--
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	===Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin===		===Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19801541}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19801541 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19801541}}

	==About this Structure==		==About this Structure==
	3INA is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA].		3INA is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19801541</ref><references group="xtra"/>
	[[Category: Bacteroides thetaiotaomicron]]		[[Category: Bacteroides thetaiotaomicron]]
	[[Category: Han, Y H.]]		[[Category: Han, Y H.]]
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	[[Category: Lyase]]		[[Category: Lyase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Sep 30 09~~:31:05 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 14:37:00 2009''

OCA at 07:31, 30 September 2009

2009-09-30T07:31:06Z

←Older revision		Revision as of 07:31, 30 September 2009
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3ina.jpg\|left\|200px]]

-	The ~~entry 3ina~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3ina", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3ina\| PDB=3ina \| SCENE= }}

-	~~Authors: Han, Y.H., Ryu, K.S., Kim, H.Y., Jeon, Y.H.~~	+	===Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin===

-	Description: Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu~~ Sep ~~3 15~~:21:51 2009''	+	==About this Structure==
		+	3INA is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INA OCA].
		+	[[Category: Bacteroides thetaiotaomicron]]
		+	[[Category: Han, Y H.]]
		+	[[Category: Jeon, Y H.]]
		+	[[Category: Kim, H Y.]]
		+	[[Category: Ryu, K S.]]
		+	[[Category: Jelly roll]]
		+	[[Category: Lyase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 09:31:05 2009''