3jux - Revision history

OCA at 08:04, 6 September 2023

2023-09-06T08:04:00Z

←Older revision		Revision as of 08:04, 6 September 2023
Line 1:		Line 1:

	==Structure of the translocation ATPase SecA from Thermotoga maritima==		==Structure of the translocation ATPase SecA from Thermotoga maritima==
-	<StructureSection load='3jux' size='340' side='right' caption='[[3jux]], [[Resolution\|resolution]] 3.10Å' scene=''>	+	<StructureSection load='3jux' size='340' side='right'caption='[[3jux]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jux]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_43589 Atcc 43589~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3JUX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jux]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JUX FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=ADP:ADENOSINE~~-~~5-DIPHOSPHATE'>ADP</scene>~~, ~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.1Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~secA, TM_1578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=5~~&id~~=~~2336 ATCC 43589])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3jux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jux OCA], [~~http~~://pdbe.org/3jux PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3jux RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3jux PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3jux ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jux OCA], [https://pdbe.org/3jux PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jux RCSB], [https://www.ebi.ac.uk/pdbsum/3jux PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jux ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/SECA_THEMA SECA_THEMA]] Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity).	+	[https://www.uniprot.org/uniprot/SECA_THEMA SECA_THEMA] Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 43589~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Zimmer, J~~]]	+	[[Category: Thermotoga maritima]]
-	[[Category: ~~Atp-binding]]~~	+	[[Category: Zimmer J]]
-	~~[[Category: Atpase]]~~	+
-	~~[[Category: Cell inner membrane]]~~	+
-	~~[[Category: Cell membrane]]~~	+
-	~~[[Category: Conformational change]]~~	+
-	~~[[Category: Cytoplasm]]~~	+
-	~~[[Category: Membrane]]~~	+
-	~~[[Category: Nucleotide-binding]]~~	+
-	~~[[Category: Peptide binding]]~~	+
-	~~[[Category: Protein translocation]]~~	+
-	~~[[Category: Protein transport]]~~	+
-	~~[[Category: Translocation]]~~	+
-	~~[[Category: Transport~~]]	+

OCA at 09:24, 26 December 2018

2018-12-26T09:24:19Z

←Older revision		Revision as of 09:24, 26 December 2018
Line 1:		Line 1:
		+
	==Structure of the translocation ATPase SecA from Thermotoga maritima==		==Structure of the translocation ATPase SecA from Thermotoga maritima==
	<StructureSection load='3jux' size='340' side='right' caption='[[3jux]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='3jux' size='340' side='right' caption='[[3jux]], [[Resolution\|resolution]] 3.10Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secA, TM_1578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secA, TM_1578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jux OCA], [http://pdbe.org/3jux PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jux RCSB], [http://www.ebi.ac.uk/pdbsum/3jux PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jux OCA], [http://pdbe.org/3jux PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jux RCSB], [http://www.ebi.ac.uk/pdbsum/3jux PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jux ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/3jux_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/3jux_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 43:		Line 44:
	[[Category: Cell membrane]]		[[Category: Cell membrane]]
	[[Category: Conformational change]]		[[Category: Conformational change]]
		+	[[Category: Cytoplasm]]
	[[Category: Membrane]]		[[Category: Membrane]]
	[[Category: Nucleotide-binding]]		[[Category: Nucleotide-binding]]

OCA at 18:39, 8 February 2016

2016-02-08T18:39:17Z

←Older revision		Revision as of 18:39, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='3jux' size='340' side='right' caption='[[3jux]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='3jux' size='340' side='right' caption='[[3jux]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jux]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermotoga_maritima Thermotoga maritima~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JUX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jux]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JUX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secA, TM_1578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ~~Thermotoga maritima~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secA, TM_1578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jux OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jux RCSB], [http://www.ebi.ac.uk/pdbsum/3jux PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jux OCA], [http://pdbe.org/3jux PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jux RCSB], [http://www.ebi.ac.uk/pdbsum/3jux PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jux ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3jux" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermotoga maritima~~]]	+	[[Category: Atcc 43589]]
	[[Category: Zimmer, J]]		[[Category: Zimmer, J]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]

OCA at 01:22, 25 December 2014

2014-12-25T01:22:02Z

←Older revision		Revision as of 01:22, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3jux]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JUX FirstGlance]. <br>		<table><tr><td colspan='2'>[[3jux]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JUX FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secA, TM_1578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secA, TM_1578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jux OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jux RCSB], [http://www.ebi.ac.uk/pdbsum/3jux PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jux OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jux RCSB], [http://www.ebi.ac.uk/pdbsum/3jux PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SECA_THEMA SECA_THEMA]] Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
-	[[Category: Zimmer, J.]]	+	[[Category: Zimmer, J]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Atpase]]		[[Category: Atpase]]

OCA at 13:15, 29 September 2014

2014-09-29T13:15:08Z

←Older revision		Revision as of 13:15, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~3jux.~~png~~\|~~left~~\|200px]]	+	==Structure of the translocation ATPase SecA from Thermotoga maritima==
		+	<StructureSection load='3jux' size='340' side='right' caption='[[3jux]], [[Resolution\|resolution]] 3.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3jux]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JUX FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secA, TM_1578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jux OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jux RCSB], [http://www.ebi.ac.uk/pdbsum/3jux PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/3jux_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The SecA ATPase forms a functional complex with the protein-conducting SecY channel to translocate polypeptides across the bacterial cell membrane. SecA recognizes the translocation substrate and catalyzes its unidirectional movement through the SecY channel. The recent crystal structure of the Thermotoga maritima SecA-SecYEG complex shows the ATPase in a conformation where the nucleotide-binding domains (NBDs) have closed around a bound ADP-BeFx complex and SecA's polypeptide-binding clamp is shut. Here, we present the crystal structure of T. maritima SecA in isolation, determined in its ADP-bound form at 3.1 A resolution. SecA alone has a drastically different conformation in which the nucleotide-binding pocket between NBD1 and NBD2 is open and the preprotein cross-linking domain has rotated away from both NBDs, thereby opening the polypeptide-binding clamp. To investigate how this clamp binds polypeptide substrates, we also determined a structure of Bacillus subtilis SecA in complex with a peptide at 2.5 A resolution. This structure shows that the peptide augments the highly conserved beta-sheet at the back of the clamp. Taken together, these structures suggest a mechanism by which ATP hydrolysis can lead to polypeptide translocation.

-	~~{{STRUCTURE_3jux\| PDB=3jux \| SCENE= }}~~	+	Conformational flexibility and peptide interaction of the translocation ATPase SecA.,Zimmer J, Rapoport TA J Mol Biol. 2009 Dec 11;394(4):606-12. Epub 2009 Oct 20. PMID:19850053<ref>PMID:19850053</ref>

-	~~===Structure~~ of the ~~translocation ATPase SecA from Thermotoga maritima===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19850053}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3jux]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermotoga_maritima Thermotoga maritima]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA].~~	+

	==See Also==		==See Also==
		+	*[[Preprotein translocase\|Preprotein translocase]]
	*[[SecA\|SecA]]		*[[SecA\|SecA]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019850053<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
	[[Category: Zimmer, J.]]		[[Category: Zimmer, J.]]

OCA at 11:05, 20 October 2012

2012-10-20T11:05:56Z

←Older revision		Revision as of 11:05, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3jux]] is a 1 chain structure ~~of [[SecA]]~~ with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA].	+	[[3jux]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA].

	==See Also==		==See Also==

OCA: Protected "3jux" [edit=sysop:move=sysop]

2012-07-26T04:14:19Z

Protected "3jux" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:14, 26 July 2012

OCA at 04:14, 26 July 2012

2012-07-26T04:14:18Z

←Older revision		Revision as of 04:14, 26 July 2012
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-	{{Seed}}
	[[Image:3jux.png\|left\|200px]]		[[Image:3jux.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3jux", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3jux\| PDB=3jux \| SCENE= }}		{{STRUCTURE_3jux\| PDB=3jux \| SCENE= }}

	===Structure of the translocation ATPase SecA from Thermotoga maritima===		===Structure of the translocation ATPase SecA from Thermotoga maritima===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19850053}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19850053 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_19850053}}		{{ABSTRACT_PUBMED_19850053}}

	==About this Structure==		==About this Structure==
-	~~3JUX~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA].	+	[[3jux]] is a 1 chain structure of [[SecA]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA].
		+
		+	==See Also==
		+	*[[SecA\|SecA]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19850053~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019850053</ref><references group="xtra"/>
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
	[[Category: Zimmer, J.]]		[[Category: Zimmer, J.]]
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	[[Category: Cell membrane]]		[[Category: Cell membrane]]
	[[Category: Conformational change]]		[[Category: Conformational change]]
-	[[Category: Cytoplasm]]
	[[Category: Membrane]]		[[Category: Membrane]]
	[[Category: Nucleotide-binding]]		[[Category: Nucleotide-binding]]
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	[[Category: Translocation]]		[[Category: Translocation]]
	[[Category: Transport]]		[[Category: Transport]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 13:08:37 2010''

OCA at 11:08, 13 January 2010

2010-01-13T11:08:37Z

←Older revision		Revision as of 11:08, 13 January 2010
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	{{Seed}}		{{Seed}}
-	[[Image:3jux.~~jpg~~\|left\|200px]]	+	[[Image:3jux.png\|left\|200px]]

	<!--		<!--
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	===Structure of the translocation ATPase SecA from Thermotoga maritima===		===Structure of the translocation ATPase SecA from Thermotoga maritima===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19850053}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19850053 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19850053}}

	==About this Structure==		==About this Structure==
	3JUX is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA].		3JUX is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19850053</ref><references group="xtra"/>
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
	[[Category: Zimmer, J.]]		[[Category: Zimmer, J.]]
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	[[Category: Transport]]		[[Category: Transport]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Oct 21 10~~:41:~~14 2009~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 13:08:37 2010''

OCA at 08:41, 21 October 2009

2009-10-21T08:41:16Z

←Older revision		Revision as of 08:41, 21 October 2009
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3jux.jpg\|left\|200px]]

-	The ~~entry 3jux~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3jux", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3jux\| PDB=3jux \| SCENE= }}

-	~~Authors: Zimmer, J.~~	+	===Structure of the translocation ATPase SecA from Thermotoga maritima===

-	Description: Structure of the translocation ATPase SecA from Thermotoga maritima

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Sep 23 08~~:31:10 2009''	+	==About this Structure==
		+	3JUX is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUX OCA].
		+	[[Category: Thermotoga maritima]]
		+	[[Category: Zimmer, J.]]
		+	[[Category: Atp-binding]]
		+	[[Category: Atpase]]
		+	[[Category: Cell inner membrane]]
		+	[[Category: Cell membrane]]
		+	[[Category: Conformational change]]
		+	[[Category: Cytoplasm]]
		+	[[Category: Membrane]]
		+	[[Category: Nucleotide-binding]]
		+	[[Category: Peptide binding]]
		+	[[Category: Protein translocation]]
		+	[[Category: Protein transport]]
		+	[[Category: Translocation]]
		+	[[Category: Transport]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 10:41:14 2009''