3jyp - Revision history

OCA at 08:06, 6 September 2023

2023-09-06T08:06:14Z

←Older revision		Revision as of 08:06, 6 September 2023
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	<StructureSection load='3jyp' size='340' side='right'caption='[[3jyp]], [[Resolution\|resolution]] 1.16Å' scene=''>		<StructureSection load='3jyp' size='340' side='right'caption='[[3jyp]], [[Resolution\|resolution]] 1.16Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jyp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Corgl Corgl~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JYP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jyp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_glutamicum_ATCC_13032 Corynebacterium glutamicum ATCC 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JYP FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NAD:NICOTINAMIDE~~-~~ADENINE-DINUCLEOTIDE'>NAD</scene>~~, ~~<scene name='pdbligand=QIC:(1S,3R,4S,5R)-~~1~~,3,4,5-TETRAHYDROXYCYCLOHEXANECARBOXYLIC+ACID'>QIC</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.16Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[2nlo\|2nlo]], [[3jyo\|3jyo]], [[3jyq\|3jyq]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=QIC:(1S,3R,4S,5R)-1,3,4,5-TETRAHYDROXYCYCLOHEXANECARBOXYLIC+ACID'>QIC</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">aroE, cg0504, Cgl0424 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196627 CORGL])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyp OCA], [https://pdbe.org/3jyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jyp RCSB], [https://www.ebi.ac.uk/pdbsum/3jyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jyp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyp OCA], [https://pdbe.org/3jyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jyp RCSB], [https://www.ebi.ac.uk/pdbsum/3jyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jyp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/AROE_CORGL AROE_CORGL]] Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. Seems to play a key role in the quinate degradation pathway.<ref>PMID:18566515</ref>	+	[https://www.uniprot.org/uniprot/AROE_CORGL AROE_CORGL] Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. Seems to play a key role in the quinate degradation pathway.<ref>PMID:18566515</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Corgl~~]]	+	[[Category: Corynebacterium glutamicum ATCC 13032]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hoeppner, A]]	+	[[Category: Hoeppner A]]
-	[[Category: Niefind, K]]	+	[[Category: Niefind K]]
-	[[Category: Schomburg, D]]	+	[[Category: Schomburg D]]
-	~~[[Category: Amino-acid biosynthesis]]~~	+
-	~~[[Category: Aromatic amino acid biosynthesis]]~~	+
-	~~[[Category: Nad]]~~	+
-	~~[[Category: Nadh]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Quinate]]~~	+
-	~~[[Category: Quinate dehyrogenase]]~~	+
-	~~[[Category: Ternary complex~~]]	+

OCA at 13:33, 4 May 2022

2022-05-04T13:33:11Z

←Older revision		Revision as of 13:33, 4 May 2022
Line 1:		Line 1:

	==Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH==		==Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH==
-	<StructureSection load='3jyp' size='340' side='right' caption='[[3jyp]], [[Resolution\|resolution]] 1.16Å' scene=''>	+	<StructureSection load='3jyp' size='340' side='right'caption='[[3jyp]], [[Resolution\|resolution]] 1.16Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jyp]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Corgl Corgl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3JYP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jyp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Corgl Corgl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JYP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=QIC:(1S,3R,4S,5R)-1,3,4,5-TETRAHYDROXYCYCLOHEXANECARBOXYLIC+ACID'>QIC</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=QIC:(1S,3R,4S,5R)-1,3,4,5-TETRAHYDROXYCYCLOHEXANECARBOXYLIC+ACID'>QIC</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nlo\|2nlo]], [[3jyo\|3jyo]], [[3jyq\|3jyq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2nlo\|2nlo]], [[3jyo\|3jyo]], [[3jyq\|3jyq]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aroE, cg0504, Cgl0424 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196627 CORGL])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aroE, cg0504, Cgl0424 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196627 CORGL])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3jyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyp OCA], [~~http~~://pdbe.org/3jyp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3jyp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3jyp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3jyp ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyp OCA], [https://pdbe.org/3jyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jyp RCSB], [https://www.ebi.ac.uk/pdbsum/3jyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jyp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/AROE_CORGL AROE_CORGL]] Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. Seems to play a key role in the quinate degradation pathway.<ref>PMID:18566515</ref>	+	[[https://www.uniprot.org/uniprot/AROE_CORGL AROE_CORGL]] Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. Seems to play a key role in the quinate degradation pathway.<ref>PMID:18566515</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:

	==See Also==		==See Also==
-	*[[Shikimate dehydrogenase\|Shikimate dehydrogenase]]	+	*[[Shikimate dehydrogenase 3D structures\|Shikimate dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Corgl]]		[[Category: Corgl]]
		+	[[Category: Large Structures]]
	[[Category: Hoeppner, A]]		[[Category: Hoeppner, A]]
	[[Category: Niefind, K]]		[[Category: Niefind, K]]

OCA at 05:59, 5 August 2016

2016-08-05T05:59:05Z

←Older revision		Revision as of 05:59, 5 August 2016
Line 1:		Line 1:
		+
	==Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH==		==Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH==
	<StructureSection load='3jyp' size='340' side='right' caption='[[3jyp]], [[Resolution\|resolution]] 1.16Å' scene=''>		<StructureSection load='3jyp' size='340' side='right' caption='[[3jyp]], [[Resolution\|resolution]] 1.16Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jyp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Corynebacterium_glutamicum_atcc_13032 Corynebacterium glutamicum atcc 13032~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JYP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jyp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corgl Corgl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JYP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=QIC:(1S,3R,4S,5R)-1,3,4,5-TETRAHYDROXYCYCLOHEXANECARBOXYLIC+ACID'>QIC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=QIC:(1S,3R,4S,5R)-1,3,4,5-TETRAHYDROXYCYCLOHEXANECARBOXYLIC+ACID'>QIC</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nlo\|2nlo]], [[3jyo\|3jyo]], [[3jyq\|3jyq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nlo\|2nlo]], [[3jyo\|3jyo]], [[3jyq\|3jyq]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aroE, cg0504, Cgl0424 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196627 ~~Corynebacterium glutamicum ATCC 13032~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aroE, cg0504, Cgl0424 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196627 CORGL])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jyp RCSB], [http://www.ebi.ac.uk/pdbsum/3jyp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyp OCA], [http://pdbe.org/3jyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jyp RCSB], [http://www.ebi.ac.uk/pdbsum/3jyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jyp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3jyp" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 25:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Corynebacterium glutamicum atcc 13032~~]]	+	[[Category: Corgl]]
	[[Category: Hoeppner, A]]		[[Category: Hoeppner, A]]
	[[Category: Niefind, K]]		[[Category: Niefind, K]]

OCA at 23:37, 24 December 2014

2014-12-24T23:37:31Z

←Older revision		Revision as of 23:37, 24 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jyp RCSB], [http://www.ebi.ac.uk/pdbsum/3jyp PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jyp RCSB], [http://www.ebi.ac.uk/pdbsum/3jyp PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AROE_CORGL AROE_CORGL]] Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. Seems to play a key role in the quinate degradation pathway.<ref>PMID:18566515</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 17:02, 18 December 2014

2014-12-18T17:02:52Z

←Older revision		Revision as of 17:02, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3jyp~~\| ~~PDB~~=3jyp \| ~~SCENE~~= }}	+	==Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH==
-	===Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate ~~and~~ NADH~~===~~	+	<StructureSection load='3jyp' size='340' side='right' caption='[[3jyp]], [[Resolution\|resolution]] 1.16Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23929881}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3jyp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_glutamicum_atcc_13032 Corynebacterium glutamicum atcc 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JYP FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=QIC:(1S,3R,4S,5R)-1,3,4,5-TETRAHYDROXYCYCLOHEXANECARBOXYLIC+ACID'>QIC</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nlo\|2nlo]], [[3jyo\|3jyo]], [[3jyq\|3jyq]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aroE, cg0504, Cgl0424 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196627 Corynebacterium glutamicum ATCC 13032])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jyp RCSB], [http://www.ebi.ac.uk/pdbsum/3jyp PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Abstract Quinate dehydrogenase (QDH) catalyzes the reversible oxidation of quinate to 3-dehydroquinate by NADH and is involved in the catabolic quinate metabolism required for the degradation of lignin. The enzyme is a member of the family of shikimate/quinate dehydrogenases (SDH/QDH) occurring in bacteria and plants. We characterized the dual-substrate quinate/shikimate dehydrogenase QSDH from Corynebacterium glutamicum (CglQSDH) kinetically and revealed a clear substrate preference of CglQSDH for quinate compared to shikimate both at the pH-optimum and in a physiological pH-range, which is a remarkable contrast to closely related SDH/QDH enzymes. With respect to the cosubstrate CglQSDH is strictly NAD(H) dependent. These substrate and cosubstrate profiles correlate nicely to the details of three atomic resolution crystal structures of CglQSDH in different functional states we report here: with bound NAD+ (binary complex) and as ternary complexes with NADH plus either shikimate or quinate. The CglQSDH-NADH-quinate structure is the first complex structure of any member of the SDH/QDH family with quinate. Based on this novel structural information and systematic sequence and structure comparisons with closely related enzymes we can explain the strict NAD(H) dependency of CglQSDH as well as its discrimination between shikimate and quinate.

-	~~==Function==~~	+	Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity and discrimination.,Hoppner A, Schomburg D, Niefind K Biol Chem. 2013 Aug 8. pii:, /j/bchm.just-accepted/hsz-2013-0170/hsz-2013-0170.xml. doi:, 10.1515/hsz-2013-0170. PMID:23929881<ref>PMID:23929881</ref>
-	~~[[http:/~~/~~www~~.~~uniprot~~.~~org~~/~~uniprot~~/~~AROE_CORGL AROE_CORGL]] Catalyzes the NAD(+)~~-~~dependent oxidation of both quinate and shikimate to 3~~-~~dehydroquinate and 3~~-~~dehydroshikimate~~, ~~respectively~~. ~~Seems to play a key role in the quinate degradation pathway~~.<ref>PMID:~~18566515~~</ref>	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3jyp]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Corynebacterium_glutamicum_atcc_13032 Corynebacterium glutamicum atcc 13032]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA].~~	+	</div>

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:023929881</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	*[[Shikimate dehydrogenase\|Shikimate dehydrogenase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Corynebacterium glutamicum atcc 13032]]		[[Category: Corynebacterium glutamicum atcc 13032]]
-	[[Category: Hoeppner, A.]]	+	[[Category: Hoeppner, A]]
-	[[Category: Niefind, K.]]	+	[[Category: Niefind, K]]
-	[[Category: Schomburg, D.]]	+	[[Category: Schomburg, D]]
	[[Category: Amino-acid biosynthesis]]		[[Category: Amino-acid biosynthesis]]
	[[Category: Aromatic amino acid biosynthesis]]		[[Category: Aromatic amino acid biosynthesis]]

OCA at 08:43, 4 September 2013

2013-09-04T08:43:54Z

←Older revision		Revision as of 08:43, 4 September 2013
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	{{STRUCTURE_3jyp\| PDB=3jyp \| SCENE= }}		{{STRUCTURE_3jyp\| PDB=3jyp \| SCENE= }}
	===Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH===		===Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH===
		+	{{ABSTRACT_PUBMED_23929881}}

	==Function==		==Function==
-	[[http://www.uniprot.org/uniprot/AROE_CORGL AROE_CORGL]] Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. Seems to play a key role in the quinate degradation pathway.<ref>PMID:18566515</ref>	+	[[http://www.uniprot.org/uniprot/AROE_CORGL AROE_CORGL]] Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. Seems to play a key role in the quinate degradation pathway.<ref>PMID:18566515</ref>

	==About this Structure==		==About this Structure==
-	[[3jyp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Corynebacterium_glutamicum~~ Corynebacterium glutamicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA].	+	[[3jyp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_glutamicum_atcc_13032 Corynebacterium glutamicum atcc 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA].

	==Reference==		==Reference==
-	<references group="xtra"/><references/>	+	<ref group="xtra">PMID:023929881</ref><references group="xtra"/><references/>
-	[[Category: Corynebacterium glutamicum]]	+	[[Category: Corynebacterium glutamicum atcc 13032]]
	[[Category: Hoeppner, A.]]		[[Category: Hoeppner, A.]]
	[[Category: Niefind, K.]]		[[Category: Niefind, K.]]

OCA: Protected "3jyp" [edit=sysop:move=sysop]

2013-03-27T09:14:38Z

Protected "3jyp" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:14, 27 March 2013

OCA at 09:14, 27 March 2013

2013-03-27T09:14:35Z

←Older revision		Revision as of 09:14, 27 March 2013
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-	{{Seed}}
-	[[Image:3jyp.jpg\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3jyp", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3jyp\| PDB=3jyp \| SCENE= }}		{{STRUCTURE_3jyp\| PDB=3jyp \| SCENE= }}
-
	===Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH===		===Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH===

		+	==Function==
		+	[[http://www.uniprot.org/uniprot/AROE_CORGL AROE_CORGL]] Catalyzes the NAD(+)-dependent oxidation of both quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate, respectively. Seems to play a key role in the quinate degradation pathway.<ref>PMID:18566515</ref>

	==About this Structure==		==About this Structure==
-	~~3JYP~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_glutamicum Corynebacterium glutamicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA].	+	[[3jyp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_glutamicum Corynebacterium glutamicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA].
		+
		+	==Reference==
		+	<references group="xtra"/><references/>
	[[Category: Corynebacterium glutamicum]]		[[Category: Corynebacterium glutamicum]]
	[[Category: Hoeppner, A.]]		[[Category: Hoeppner, A.]]
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	[[Category: Quinate dehyrogenase]]		[[Category: Quinate dehyrogenase]]
	[[Category: Ternary complex]]		[[Category: Ternary complex]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 27 12:07:07 2010''

OCA at 08:56, 27 October 2010

2010-10-27T08:56:46Z

←Older revision		Revision as of 08:56, 27 October 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3jyp.jpg\|left\|200px]]

-	The ~~entry 3jyp~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3jyp", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3jyp\| PDB=3jyp \| SCENE= }}

-	~~Authors: Hoeppner, A., Schomburg, D., Niefind, K.~~	+	===Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH===

-	Description: Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct ~~14 10~~:06:~~47 2009~~''	+	==About this Structure==
		+	3JYP is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_glutamicum Corynebacterium glutamicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JYP OCA].
		+	[[Category: Corynebacterium glutamicum]]
		+	[[Category: Hoeppner, A.]]
		+	[[Category: Niefind, K.]]
		+	[[Category: Schomburg, D.]]
		+	[[Category: Amino-acid biosynthesis]]
		+	[[Category: Aromatic amino acid biosynthesis]]
		+	[[Category: Nad]]
		+	[[Category: Nadh]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Quinate]]
		+	[[Category: Quinate dehyrogenase]]
		+	[[Category: Ternary complex]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 27 12:07:07 2010''

OCA at 08:06, 14 October 2009

2009-10-14T08:06:48Z

←Older revision		Revision as of 08:06, 14 October 2009
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3jyp is ON HOLD	+	The entry 3jyp is ON HOLD until Paper Publication

	Authors: Hoeppner, A., Schomburg, D., Niefind, K.		Authors: Hoeppner, A., Schomburg, D., Niefind, K.
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	Description: Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH		Description: Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Sep 30 09~~:01:15 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:06:47 2009''