3ka6 - Revision history

OCA at 08:12, 6 September 2023

2023-09-06T08:12:40Z

←Older revision		Revision as of 08:12, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3ka6' size='340' side='right'caption='[[3ka6]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='3ka6' size='340' side='right'caption='[[3ka6]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ka6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~American_bullfrog American bullfrog~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KA6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ka6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_catesbeianus Lithobates catesbeianus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KA6 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3ka3\|3ka3]], [[3ka4\|3ka4]], [[3ka8\|3ka8]], [[3ka9\|3ka9]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ka6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka6 OCA], [https://pdbe.org/3ka6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ka6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ka6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ka6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ka6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka6 OCA], [https://pdbe.org/3ka6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ka6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ka6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ka6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/FRI2_LITCT FRI2_LITCT]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	+	[https://www.uniprot.org/uniprot/FRI2_LITCT FRI2_LITCT] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: American bullfrog]]
-	[[Category: Ferroxidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Alber, T]]	+	[[Category: Lithobates catesbeianus]]
-	[[Category: Bhattasali, O]]	+	[[Category: Alber T]]
-	[[Category: Ng~~, H L~~]]	+	[[Category: Bhattasali O]]
-	[[Category: Theil, E]]	+	[[Category: Ng HL]]
-	[[Category: Tosha, T]]	+	[[Category: Theil E]]
-	~~[[Category: Diiron]]~~	+	[[Category: Tosha T]]
-	~~[[Category: Iron]]~~	+
-	~~[[Category: Iron storage]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 12:23, 13 October 2021

2021-10-13T12:23:08Z

←Older revision		Revision as of 12:23, 13 October 2021
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	<StructureSection load='3ka6' size='340' side='right'caption='[[3ka6]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='3ka6' size='340' side='right'caption='[[3ka6]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ka6]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/American_bullfrog American bullfrog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3KA6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ka6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/American_bullfrog American bullfrog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KA6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ka3\|3ka3]], [[3ka4\|3ka4]], [[3ka8\|3ka8]], [[3ka9\|3ka9]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ka3\|3ka3]], [[3ka4\|3ka4]], [[3ka8\|3ka8]], [[3ka9\|3ka9]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3ka6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka6 OCA], [~~http~~://pdbe.org/3ka6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ka6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ka6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ka6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ka6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka6 OCA], [https://pdbe.org/3ka6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ka6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ka6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ka6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/FRI2_LITCT FRI2_LITCT]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	+	[[https://www.uniprot.org/uniprot/FRI2_LITCT FRI2_LITCT]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:01, 7 October 2020

2020-10-07T07:01:03Z

←Older revision		Revision as of 07:01, 7 October 2020
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	==Frog M-ferritin, EED mutant, with cobalt==		==Frog M-ferritin, EED mutant, with cobalt==
-	<StructureSection load='3ka6' size='340' side='right' caption='[[3ka6]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='3ka6' size='340' side='right'caption='[[3ka6]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ka6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/American_bullfrog American bullfrog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3KA6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ka6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/American_bullfrog American bullfrog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3KA6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ka3\|3ka3]], [[3ka4\|3ka4]], [[3ka8\|3ka8]], [[3ka9\|3ka9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ka3\|3ka3]], [[3ka4\|3ka4]], [[3ka8\|3ka8]], [[3ka9\|3ka9]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ka6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka6 OCA], [http://pdbe.org/3ka6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ka6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ka6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ka6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3ka6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka6 OCA], [http://pdbe.org/3ka6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ka6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ka6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ka6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Ferritin\|Ferritin]]	+	*[[Ferritin 3D structures\|Ferritin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 39:		Line 39:
	[[Category: American bullfrog]]		[[Category: American bullfrog]]
	[[Category: Ferroxidase]]		[[Category: Ferroxidase]]
		+	[[Category: Large Structures]]
	[[Category: Alber, T]]		[[Category: Alber, T]]
	[[Category: Bhattasali, O]]		[[Category: Bhattasali, O]]

OCA at 09:28, 26 December 2018

2018-12-26T09:28:36Z

←Older revision		Revision as of 09:28, 26 December 2018
Line 15:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/3ka6_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/3ka6_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 23:26, 4 August 2016

2016-08-04T23:26:31Z

←Older revision		Revision as of 23:26, 4 August 2016
Line 1:		Line 1:
		+
	==Frog M-ferritin, EED mutant, with cobalt==		==Frog M-ferritin, EED mutant, with cobalt==
	<StructureSection load='3ka6' size='340' side='right' caption='[[3ka6]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='3ka6' size='340' side='right' caption='[[3ka6]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ka6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rana_catesbeiana Rana catesbeiana~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KA6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ka6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/American_bullfrog American bullfrog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KA6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ka3\|3ka3]], [[3ka4\|3ka4]], [[3ka8\|3ka8]], [[3ka9\|3ka9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ka3\|3ka3]], [[3ka4\|3ka4]], [[3ka8\|3ka8]], [[3ka9\|3ka9]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ka6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ka6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ka6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ka6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka6 OCA], [http://pdbe.org/3ka6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ka6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ka6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ka6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~FRI2_RANCA FRI2_RANCA~~]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	+	[[http://www.uniprot.org/uniprot/FRI2_LITCT FRI2_LITCT]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ka6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ka6" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: American bullfrog]]
	[[Category: Ferroxidase]]		[[Category: Ferroxidase]]
-	[[Category: Rana catesbeiana]]
	[[Category: Alber, T]]		[[Category: Alber, T]]
	[[Category: Bhattasali, O]]		[[Category: Bhattasali, O]]

OCA at 20:40, 24 December 2014

2014-12-24T20:40:21Z

←Older revision		Revision as of 20:40, 24 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ka6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ka6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ka6 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ka6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ka6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ka6 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FRI2_RANCA FRI2_RANCA]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 09:35, 9 December 2014

2014-12-09T09:35:31Z

←Older revision		Revision as of 09:35, 9 December 2014
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-	[[~~Image:~~3ka6.~~png~~\|~~left~~\|200px]]	+	==Frog M-ferritin, EED mutant, with cobalt==
		+	<StructureSection load='3ka6' size='340' side='right' caption='[[3ka6]], [[Resolution\|resolution]] 1.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ka6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rana_catesbeiana Rana catesbeiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KA6 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ka3\|3ka3]], [[3ka4\|3ka4]], [[3ka8\|3ka8]], [[3ka9\|3ka9]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ka6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ka6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ka6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ka6 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/3ka6_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Ferritin nanocages synthesize ferric oxide minerals, containing hundreds to thousands of Fe(III) diferric oxo/hydroxo complexes, by reactions of Fe(II) ions with O(2) at multiple di-iron catalytic centers. Ferric-oxy multimers, tetramers, and/or larger mineral nuclei form during postcatalytic transit through the protein cage, and mineral accretion occurs in the central cavity. We determined how Fe(II) substrates can access catalytic sites using frog M ferritins, active and inactivated by ligand substitution, crystallized with 2.0 M Mg(II) +/- 0.1 M Co(II) for Co(II)-selective sites. Co(II) inhibited Fe(II) oxidation. High-resolution (<1.5 A) crystal structures show (1) a line of metal ions, 15 A long, which penetrates the cage and defines ion channels and internal pores to the nanocavity that link external pores to the cage interior, (2) metal ions near negatively charged residues at the channel exits and along the inner cavity surface that model Fe(II) transit to active sites, and (3) alternate side-chain conformations, absent in ferritins with catalysis eliminated by amino acid substitution, which support current models of protein dynamics and explain changes in Fe-Fe distances observed during catalysis. The new structural data identify a approximately 27-A path Fe(II) ions can follow through ferritin entry channels between external pores and the central cavity and along the cavity surface to the active sites where mineral synthesis begins. This "bucket brigade" for Fe(II) ion access to the ferritin catalytic sites not only increases understanding of biological nanomineral synthesis but also reveals unexpected design principles for protein cage-based catalysts and nanomaterials.

-	~~{{STRUCTURE_3ka6\| PDB=3ka6 \| SCENE= }}~~	+	Moving metal ions through ferritin-protein nanocages from three-fold pores to catalytic sites.,Tosha T, Ng HL, Bhattasali O, Alber T, Theil EC J Am Chem Soc. 2010 Oct 20;132(41):14562-9. PMID:20866049<ref>PMID:20866049</ref>

-	~~===Frog M-ferritin~~, ~~EED mutant, with cobalt===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20866049}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3ka6]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rana_catesbeiana Rana catesbeiana]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA].~~	+

	==See Also==		==See Also==
	*[[Ferritin\|Ferritin]]		*[[Ferritin\|Ferritin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020866049<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Ferroxidase]]		[[Category: Ferroxidase]]
	[[Category: Rana catesbeiana]]		[[Category: Rana catesbeiana]]
-	[[Category: Alber, T.]]	+	[[Category: Alber, T]]
-	[[Category: Bhattasali, O.]]	+	[[Category: Bhattasali, O]]
-	[[Category: Ng, H L.]]	+	[[Category: Ng, H L]]
-	[[Category: Theil, E.]]	+	[[Category: Theil, E]]
-	[[Category: Tosha, T.]]	+	[[Category: Tosha, T]]
	[[Category: Diiron]]		[[Category: Diiron]]
	[[Category: Iron]]		[[Category: Iron]]

OCA at 08:56, 20 October 2012

2012-10-20T08:56:07Z

←Older revision		Revision as of 08:56, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[3ka6]] is a 1 chain structure ~~of [[Ferritin]]~~ with sequence from [http://en.wikipedia.org/wiki/Rana_catesbeiana Rana catesbeiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA].	+	[[3ka6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rana_catesbeiana Rana catesbeiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA6 OCA].

	==See Also==		==See Also==

OCA at 21:14, 25 July 2012

2012-07-25T21:14:58Z

←Older revision		Revision as of 21:14, 25 July 2012
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	[[Image:3ka6.png\|left\|200px]]		[[Image:3ka6.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ka6", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ka6\| PDB=3ka6 \| SCENE= }}		{{STRUCTURE_3ka6\| PDB=3ka6 \| SCENE= }}

	===Frog M-ferritin, EED mutant, with cobalt===		===Frog M-ferritin, EED mutant, with cobalt===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20866049}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20866049 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20866049}}		{{ABSTRACT_PUBMED_20866049}}

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	==See Also==		==See Also==
-	*[[Ferritin]]	+	*[[Ferritin\|Ferritin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20866049~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020866049</ref><references group="xtra"/>
	[[Category: Ferroxidase]]		[[Category: Ferroxidase]]
	[[Category: Rana catesbeiana]]		[[Category: Rana catesbeiana]]

OCA: Protected "3ka6" [edit=sysop:move=sysop]

2010-12-27T01:40:37Z

Protected "3ka6" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:40, 27 December 2010