3kan - Revision history

OCA at 08:13, 6 September 2023

2023-09-06T08:13:04Z

←Older revision		Revision as of 08:13, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3kan' size='340' side='right'caption='[[3kan]], [[Resolution\|resolution]] 1.13Å' scene=''>		<StructureSection load='3kan' size='340' side='right'caption='[[3kan]], [[Resolution\|resolution]] 1.13Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kan]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KAN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kan]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KAN FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=RW1:4-PHENYLPYRIMIDINE'>RW1</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.13Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3b9s\|3b9s]], [[3b64\|3b64]], [[1dpt\|1dpt]], [[3ker\|3ker]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=RW1:4-PHENYLPYRIMIDINE'>RW1</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">DDT, hCG_41098 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kan OCA], [https://pdbe.org/3kan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kan RCSB], [https://www.ebi.ac.uk/pdbsum/3kan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kan ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kan OCA], [https://pdbe.org/3kan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kan RCSB], [https://www.ebi.ac.uk/pdbsum/3kan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kan ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/DOPD_HUMAN DOPD_HUMAN] Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Lolis, E]]	+	[[Category: Lolis E]]
-	[[Category: Zierow, S]]	+	[[Category: Zierow S]]
-	~~[[Category: Cytokine]]~~	+
-	~~[[Category: Cytokine-inhibitor complex]]~~	+
-	~~[[Category: Immune response]]~~	+
-	~~[[Category: Tautomerase~~]]	+

OCA at 18:31, 27 July 2022

2022-07-27T18:31:14Z

←Older revision		Revision as of 18:31, 27 July 2022
Line 3:		Line 3:
	<StructureSection load='3kan' size='340' side='right'caption='[[3kan]], [[Resolution\|resolution]] 1.13Å' scene=''>		<StructureSection load='3kan' size='340' side='right'caption='[[3kan]], [[Resolution\|resolution]] 1.13Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kan]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3KAN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kan]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KAN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=RW1:4-PHENYLPYRIMIDINE'>RW1</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=RW1:4-PHENYLPYRIMIDINE'>RW1</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3b9s\|3b9s]], [[3b64\|3b64]], [[1dpt\|1dpt]], [[3ker\|3ker]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3b9s\|3b9s]], [[3b64\|3b64]], [[1dpt\|1dpt]], [[3ker\|3ker]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DDT, hCG_41098 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DDT, hCG_41098 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3kan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kan OCA], [~~http~~://pdbe.org/3kan PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3kan RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3kan PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3kan ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kan OCA], [https://pdbe.org/3kan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kan RCSB], [https://www.ebi.ac.uk/pdbsum/3kan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kan ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 3kan" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3kan" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Macrophage inhibitory factor 3D structures\|Macrophage inhibitory factor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:20, 21 October 2020

2020-10-21T08:20:21Z

←Older revision		Revision as of 08:20, 21 October 2020
Line 1:		Line 1:

	==D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP==		==D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP==
-	<StructureSection load='3kan' size='340' side='right' caption='[[3kan]], [[Resolution\|resolution]] 1.13Å' scene=''>	+	<StructureSection load='3kan' size='340' side='right'caption='[[3kan]], [[Resolution\|resolution]] 1.13Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kan]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3KAN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kan]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3KAN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=RW1:4-PHENYLPYRIMIDINE'>RW1</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=RW1:4-PHENYLPYRIMIDINE'>RW1</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3b9s\|3b9s]], [[3b64\|3b64]], [[1dpt\|1dpt]], [[3ker\|3ker]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3b9s\|3b9s]], [[3b64\|3b64]], [[1dpt\|1dpt]], [[3ker\|3ker]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DDT, hCG_41098 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DDT, hCG_41098 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3kan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kan OCA], [http://pdbe.org/3kan PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kan RCSB], [http://www.ebi.ac.uk/pdbsum/3kan PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kan ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3kan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kan OCA], [http://pdbe.org/3kan PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kan RCSB], [http://www.ebi.ac.uk/pdbsum/3kan PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kan ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We report a new inflammatory activity for extracellular d-dopachrome tautomerase (D-DT), the recruitment of neutrophils to the lung on D-DT intratracheal installation of C57BL/6J mice with an EC50 of 5.6 mug. We also find that D-DT and macrophage migration inhibitory factor (MIF) have additive effects in neutrophil recruitment. Although the tautomerase site of D-DT and its homologue MIF are biophysically very different, 4-iodo-6-phenylpyrimidine (4-IPP) forms a covalent bond with Pro-1 of both proteins, resulting in a 6-phenylpyrimidine (6-PP) adduct. Recruitment of neutrophils to the lung for the 6-PP adducts of D-DT and MIF are reduced by approximately 50% relative to the apo proteins, demonstrating that an unmodified Pro-1 is important for this activity, but there is no cooperativity in inhibition of the proteins together. The differences in the binding mode of the 6-PP adduct for D-DT was determined by crystallographic studies at 1.13 A resolution and compared to the structure of the MIF-6-PP complex. There are major differences in the location of the 6-PP adduct to the D-DT and MIF active sites that provide insight into the lack of cooperativity by 4-IPP and into tuning the properties of the covalent inhibitors of D-DT and MIF that are necessary for the development of therapeutic small molecules against neutrophil damage from lung infections such as Pseudomonas aeruginosa in cystic fibrosis and immunocompromised patients.-Rajasekaran, D., Zierow, S., Syed, M., Bucala, R., Bhandari, V., Lolis, E. J. Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment.
		+
		+	Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment.,Rajasekaran D, Zierow S, Syed M, Bucala R, Bhandari V, Lolis EJ FASEB J. 2014 Jul 11. pii: fj.14-256636. PMID:25016026<ref>PMID:25016026</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 3kan" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Lolis, E]]		[[Category: Lolis, E]]
	[[Category: Zierow, S]]		[[Category: Zierow, S]]

OCA at 19:55, 4 August 2016

2016-08-04T19:55:17Z

←Older revision		Revision as of 19:55, 4 August 2016
Line 1:		Line 1:
		+
	==D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP==		==D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP==
	<StructureSection load='3kan' size='340' side='right' caption='[[3kan]], [[Resolution\|resolution]] 1.13Å' scene=''>		<StructureSection load='3kan' size='340' side='right' caption='[[3kan]], [[Resolution\|resolution]] 1.13Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kan]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KAN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kan]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KAN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=RW1:4-PHENYLPYRIMIDINE'>RW1</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=RW1:4-PHENYLPYRIMIDINE'>RW1</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3b9s\|3b9s]], [[3b64\|3b64]], [[1dpt\|1dpt]], [[3ker\|3ker]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3b9s\|3b9s]], [[3b64\|3b64]], [[1dpt\|1dpt]], [[3ker\|3ker]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DDT, hCG_41098 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DDT, hCG_41098 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kan OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kan RCSB], [http://www.ebi.ac.uk/pdbsum/3kan PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kan OCA], [http://pdbe.org/3kan PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kan RCSB], [http://www.ebi.ac.uk/pdbsum/3kan PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kan ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Lolis, E]]		[[Category: Lolis, E]]
	[[Category: Zierow, S]]		[[Category: Zierow, S]]

OCA at 22:10, 3 January 2015

2015-01-03T22:10:48Z

←Older revision		Revision as of 22:10, 3 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3kan]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KAN FirstGlance]. <br>		<table><tr><td colspan='2'>[[3kan]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KAN FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=RW1:4-PHENYLPYRIMIDINE'>RW1</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=RW1:4-PHENYLPYRIMIDINE'>RW1</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3b9s\|3b9s]], [[3b64\|3b64]], [[1dpt\|1dpt]], [[3ker\|3ker]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3b9s\|3b9s]], [[3b64\|3b64]], [[1dpt\|1dpt]], [[3ker\|3ker]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DDT, hCG_41098 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DDT, hCG_41098 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kan OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kan RCSB], [http://www.ebi.ac.uk/pdbsum/3kan PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kan OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kan RCSB], [http://www.ebi.ac.uk/pdbsum/3kan PDBsum]</span></td></tr>
-	<table>	+	</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Lolis, E.]]	+	[[Category: Lolis, E]]
-	[[Category: Zierow, S.]]	+	[[Category: Zierow, S]]
	[[Category: Cytokine]]		[[Category: Cytokine]]
	[[Category: Cytokine-inhibitor complex]]		[[Category: Cytokine-inhibitor complex]]
	[[Category: Immune response]]		[[Category: Immune response]]
	[[Category: Tautomerase]]		[[Category: Tautomerase]]

OCA at 09:49, 21 May 2014

2014-05-21T09:49:31Z

←Older revision		Revision as of 09:49, 21 May 2014
Line 1:		Line 1:
-	~~[[Image:3kan.jpg\|left\|200px]]~~	+	==D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP==
-		+	<StructureSection load='3kan' size='340' side='right' caption='[[3kan]], [[Resolution\|resolution]] 1.13Å' scene=''>
-	~~<!--~~	+	== Structural highlights ==
-	~~The line below this paragraph, containing "STRUCTURE_3kan", creates the "Structure Box" on the page.~~	+	<table><tr><td colspan='2'>[[3kan]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KAN FirstGlance]. <br>
-	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=RW1:4-PHENYLPYRIMIDINE'>RW1</scene><br>
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3b9s\|3b9s]], [[3b64\|3b64]], [[1dpt\|1dpt]], [[3ker\|3ker]]</td></tr>
-	~~or leave the SCENE parameter empty for the default display.~~	+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DDT, hCG_41098 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	~~-->~~	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kan OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kan RCSB], [http://www.ebi.ac.uk/pdbsum/3kan PDBsum]</span></td></tr>
-	~~{{STRUCTURE_3kan\| PDB=3kan \| SCENE= }}~~	+	<table>
-		+	__TOC__
-	===D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP===	+	</StructureSection>
-		+
-		+
-	==~~About this Structure~~==	+
-	[[3kan]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA].	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Lolis, E.]]		[[Category: Lolis, E.]]
	[[Category: Zierow, S.]]		[[Category: Zierow, S.]]
		+	[[Category: Cytokine]]
		+	[[Category: Cytokine-inhibitor complex]]
		+	[[Category: Immune response]]
		+	[[Category: Tautomerase]]

OCA: Protected "3kan" [edit=sysop:move=sysop]

2011-04-21T10:48:30Z

Protected "3kan" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:48, 21 April 2011

OCA at 10:48, 21 April 2011

2011-04-21T10:48:26Z

←Older revision		Revision as of 10:48, 21 April 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3kan.jpg\|left\|200px]]

-	The ~~entry 3kan~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3kan", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3kan\| PDB=3kan \| SCENE= }}

-	~~Authors: Zierow, S., Lolis, E.~~	+	===D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP===

-	Description: D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed Nov 18 18~~:52:~~29 2009''~~	+	==About this Structure==
		+	[[3kan]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAN OCA].
		+	[[Category: Homo sapiens]]
		+	[[Category: Lolis, E.]]
		+	[[Category: Zierow, S.]]

OCA at 16:52, 18 November 2009

2009-11-18T16:52:30Z

←Older revision		Revision as of 16:52, 18 November 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3kan is ON HOLD	+	The entry 3kan is ON HOLD until Paper Publication

	Authors: Zierow, S., Lolis, E.		Authors: Zierow, S., Lolis, E.
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	Description: D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP		Description: D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Oct 28 12~~:59:39 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:52:29 2009''

OCA: New page: '''Unreleased structure''' The entry 3kan is ON HOLD Authors: Zierow, S., Lolis, E. Description: D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complex...

2009-10-28T10:59:40Z

New page: '''Unreleased structure''' The entry 3kan is ON HOLD Authors: Zierow, S., Lolis, E. Description: D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complex...

New page

'''Unreleased structure'''

The entry 3kan is ON HOLD

Authors: Zierow, S., Lolis, E.

Description: D-dopachrome tautomerase (D-DT)/macrophage migration inhibitory factor 2 (MIF2) complexed with inhibitor 4-IPP

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 28 12:59:39 2009''