3kia - Revision history

OCA at 16:12, 1 November 2023

2023-11-01T16:12:55Z

←Older revision		Revision as of 16:12, 1 November 2023
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	<StructureSection load='3kia' size='340' side='right'caption='[[3kia]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3kia' size='340' side='right'caption='[[3kia]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kia]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KIA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kia]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rubrobacter_xylanophilus Rubrobacter xylanophilus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KIA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=5GP:GUANOSINE~~-~~5-MONOPHOSPHATE'>5GP</scene>~~, ~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3f1y\|3f1y]], [[3e25\|3e25]], [[3e26\|3e26]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>[https://en.wikipedia.org/wiki/Mannosyl-3-phosphoglycerate_synthase Mannosyl-3-phosphoglycerate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.217 2.4.1.217] </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kia OCA], [https://pdbe.org/3kia PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kia RCSB], [https://www.ebi.ac.uk/pdbsum/3kia PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kia ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kia OCA], [https://pdbe.org/3kia PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kia RCSB], [https://www.ebi.ac.uk/pdbsum/3kia PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kia ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B7SY86_9ACTN B7SY86_9ACTN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Mannosyl-3-phosphoglycerate synthase]]
-	[[Category: Costa, M S.da]]
-	[[Category: Empadinhas, N]]
-	[[Category: Macedo-Ribeiro, S]]
-	[[Category: Pereira, P J.B]]
-	[[Category: Gdp-mannose]]
-	[[Category: Glycosyltransferase]]
-	[[Category: Gt-81]]
-	[[Category: Gt-a type glycosyltransferase]]
	[[Category: Rubrobacter xylanophilus]]		[[Category: Rubrobacter xylanophilus]]
-	[[Category: ~~Transferase~~]]	+	[[Category: Synthetic construct]]
		+	[[Category: Empadinhas N]]
		+	[[Category: Macedo-Ribeiro S]]
		+	[[Category: Pereira PJB]]
		+	[[Category: Da Costa MS]]

OCA at 13:35, 4 May 2022

2022-05-04T13:35:24Z

←Older revision		Revision as of 13:35, 4 May 2022
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	<StructureSection load='3kia' size='340' side='right'caption='[[3kia]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3kia' size='340' side='right'caption='[[3kia]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kia]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3KIA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kia]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KIA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3f1y\|3f1y]], [[3e25\|3e25]], [[3e26\|3e26]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3f1y\|3f1y]], [[3e25\|3e25]], [[3e26\|3e26]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Mannosyl-3-phosphoglycerate_synthase Mannosyl-3-phosphoglycerate synthase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.217 2.4.1.217] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Mannosyl-3-phosphoglycerate_synthase Mannosyl-3-phosphoglycerate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.217 2.4.1.217] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3kia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kia OCA], [~~http~~://pdbe.org/3kia PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3kia RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3kia PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3kia ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kia OCA], [https://pdbe.org/3kia PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kia RCSB], [https://www.ebi.ac.uk/pdbsum/3kia PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kia ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:02, 7 August 2019

2019-08-07T07:02:16Z

←Older revision		Revision as of 07:02, 7 August 2019
Line 1:		Line 1:

	==Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus==		==Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus==
-	<StructureSection load='3kia' size='340' side='right' caption='[[3kia]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='3kia' size='340' side='right'caption='[[3kia]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3kia]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KIA FirstGlance]. <br>		<table><tr><td colspan='2'>[[3kia]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KIA FirstGlance]. <br>
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Mannosyl-3-phosphoglycerate synthase]]		[[Category: Mannosyl-3-phosphoglycerate synthase]]
	[[Category: Costa, M S.da]]		[[Category: Costa, M S.da]]

OCA at 09:19, 3 August 2017

2017-08-03T09:19:15Z

←Older revision		Revision as of 09:19, 3 August 2017
Line 3:		Line 3:
	<StructureSection load='3kia' size='340' side='right' caption='[[3kia]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3kia' size='340' side='right' caption='[[3kia]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kia]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Rubxd Rubxd]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KIA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kia]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KIA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3f1y\|3f1y]], [[3e25\|3e25]], [[3e26\|3e26]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3f1y\|3f1y]], [[3e25\|3e25]], [[3e26\|3e26]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">266117 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=266117 RUBXD])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-3-phosphoglycerate_synthase Mannosyl-3-phosphoglycerate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.217 2.4.1.217] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-3-phosphoglycerate_synthase Mannosyl-3-phosphoglycerate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.217 2.4.1.217] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kia OCA], [http://pdbe.org/3kia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kia RCSB], [http://www.ebi.ac.uk/pdbsum/3kia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kia ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kia OCA], [http://pdbe.org/3kia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kia RCSB], [http://www.ebi.ac.uk/pdbsum/3kia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kia ProSAT]</span></td></tr>
Line 24:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Mannosyl-3-phosphoglycerate synthase]]		[[Category: Mannosyl-3-phosphoglycerate synthase]]
-	[[Category: Rubxd]]
	[[Category: Costa, M S.da]]		[[Category: Costa, M S.da]]
	[[Category: Empadinhas, N]]		[[Category: Empadinhas, N]]

OCA at 00:37, 5 August 2016

2016-08-05T00:37:41Z

←Older revision		Revision as of 00:37, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus==		==Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus==
	<StructureSection load='3kia' size='340' side='right' caption='[[3kia]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3kia' size='340' side='right' caption='[[3kia]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rubrobacter_xylanophilus Rubrobacter xylanophilus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KIA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rubxd Rubxd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KIA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3f1y\|3f1y]], [[3e25\|3e25]], [[3e26\|3e26]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3f1y\|3f1y]], [[3e25\|3e25]], [[3e26\|3e26]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">266117 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~49319 Rubrobacter xylanophilus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">266117 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=266117 RUBXD])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-3-phosphoglycerate_synthase Mannosyl-3-phosphoglycerate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.217 2.4.1.217] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-3-phosphoglycerate_synthase Mannosyl-3-phosphoglycerate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.217 2.4.1.217] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kia OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kia RCSB], [http://www.ebi.ac.uk/pdbsum/3kia PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kia OCA], [http://pdbe.org/3kia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kia RCSB], [http://www.ebi.ac.uk/pdbsum/3kia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kia ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3kia" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 22:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Mannosyl-3-phosphoglycerate synthase]]		[[Category: Mannosyl-3-phosphoglycerate synthase]]
-	[[Category: ~~Rubrobacter xylanophilus~~]]	+	[[Category: Rubxd]]
	[[Category: Costa, M S.da]]		[[Category: Costa, M S.da]]
	[[Category: Empadinhas, N]]		[[Category: Empadinhas, N]]
Line 31:		Line 33:
	[[Category: Gt-81]]		[[Category: Gt-81]]
	[[Category: Gt-a type glycosyltransferase]]		[[Category: Gt-a type glycosyltransferase]]
		+	[[Category: Rubrobacter xylanophilus]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 17:03, 18 December 2014

2014-12-18T17:03:52Z

←Older revision		Revision as of 17:03, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3kia\| PDB=3kia \| SCENE= }}~~	+	==Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus==
-	===Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus===	+	<StructureSection load='3kia' size='340' side='right' caption='[[3kia]], [[Resolution\|resolution]] 2.80Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21166895}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3kia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rubrobacter_xylanophilus Rubrobacter xylanophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KIA FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3f1y\|3f1y]], [[3e25\|3e25]], [[3e26\|3e26]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">266117 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=49319 Rubrobacter xylanophilus])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-3-phosphoglycerate_synthase Mannosyl-3-phosphoglycerate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.217 2.4.1.217] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kia OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kia RCSB], [http://www.ebi.ac.uk/pdbsum/3kia PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rubrobacter xylanophilus is the only actinobacterium known to accumulate the organic solute mannosylglycerate (MG); moreover, the accumulation of MG is constitutive. The key enzyme for MG synthesis, catalysing the conversion of GDP-mannose (GDP-Man) and D-3-phosphoglycerate (3-PGA) into the phosphorylated intermediate mannosyl-3-phosphoglycerate and GDP, was purified from R. xylanophilus cell extracts and the corresponding gene was expressed in E. coli. Despite the related solute glucosylglycerate (GG) having never been detected in R. xylanophilus, the cell extracts and the pure recombinant mannosyl-3-phosphoglycerate synthase (MpgS) could also synthesize glucosyl-3-phosphoglycerate (GPG), the precursor of GG, in agreement with the higher homology of the novel MpgS towards GPG-synthesizing mycobacterial glucosyl-3-phosphoglycerate synthases (GpgS) than towards MpgSs from hyper/thermophiles, known to accumulate MG under salt or thermal stress. To understand the specificity and substrate ambiguity of this novel enzyme, we determined the crystal structure of the unliganded MpgS and of its complexes with the nucleotide and sugar donors, at 2.2, 2.8 and 2.5 A resolution respectively. The first three-dimensional structures of a protein from this extremely gamma-radiation-resistant thermophile here reported show that MpgS (GT81 family) contains a GT-A like fold and clearly explain its nucleotide and sugar-donor specificity. In the GDP-Man complex, a flexible loop ((254) RQNRHQ(259) ), located close to the active site moves towards the incoming sugar moiety, providing the ligands for both magnesium ion co-ordination and sugar binding. A triple mutant of R. xylanophilus MpgS, mimicking the (206) PLAGE(210) loop stabilizing hydrogen bond network observed for mycobacterial GpgSs, reduces significantly the affinity to GDP-Man, implicating this loop in the sugar-donor discrimination.

-	~~==About this Structure==~~	+	Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity.,Empadinhas N, Pereira PJ, Albuquerque L, Costa J, Sa-Moura B, Marques AT, Macedo-Ribeiro S, da Costa MS Mol Microbiol. 2011 Jan;79(1):76-93. doi:, 10.1111/j.1365-2958.2010.07432.x. Epub 2010 Nov 2. PMID:21166895<ref>PMID:21166895</ref>
-	~~[[3kia]] is~~ a ~~2 chain structure with sequence~~ from ~~[http://en.wikipedia.org/wiki/Rubrobacter_xylanophilus~~ Rubrobacter xylanophilus]. ~~Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca~~-~~bin/ocashort?id=3KIA OCA]~~.	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:021166895</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Mannosyl-3-phosphoglycerate synthase]]		[[Category: Mannosyl-3-phosphoglycerate synthase]]
	[[Category: Rubrobacter xylanophilus]]		[[Category: Rubrobacter xylanophilus]]
-	[[Category: Costa, M S.da.]]	+	[[Category: Costa, M S.da]]
-	[[Category: Empadinhas, N.]]	+	[[Category: Empadinhas, N]]
-	[[Category: Macedo-Ribeiro, S.]]	+	[[Category: Macedo-Ribeiro, S]]
-	[[Category: Pereira, P J.B.]]	+	[[Category: Pereira, P J.B]]
	[[Category: Gdp-mannose]]		[[Category: Gdp-mannose]]
	[[Category: Glycosyltransferase]]		[[Category: Glycosyltransferase]]
	[[Category: Gt-81]]		[[Category: Gt-81]]
	[[Category: Gt-a type glycosyltransferase]]		[[Category: Gt-a type glycosyltransferase]]
-	[[Category: Mannosyl-3-phosphoglycerate synthase]]
-	[[Category: Rubrobacter xylanophilus]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 02:11, 4 April 2013

2013-04-04T02:11:55Z

←Older revision		Revision as of 02:11, 4 April 2013
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-	[[Image:3kia.png\|left\|200px]]
-
-	<!--
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-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3kia\| PDB=3kia \| SCENE= }}		{{STRUCTURE_3kia\| PDB=3kia \| SCENE= }}
-
	===Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus===		===Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_21166895}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 21166895 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_21166895}}		{{ABSTRACT_PUBMED_21166895}}

	==About this Structure==		==About this Structure==
-	[[3kia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rubrobacter_xylanophilus_dsm_9941~~ Rubrobacter xylanophilus ~~dsm 9941~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA].	+	[[3kia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rubrobacter_xylanophilus Rubrobacter xylanophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21166895~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021166895</ref><references group="xtra"/><references/>
	[[Category: Mannosyl-3-phosphoglycerate synthase]]		[[Category: Mannosyl-3-phosphoglycerate synthase]]
-	[[Category: Rubrobacter xylanophilus ~~dsm 9941~~]]	+	[[Category: Rubrobacter xylanophilus]]
	[[Category: Costa, M S.da.]]		[[Category: Costa, M S.da.]]
	[[Category: Empadinhas, N.]]		[[Category: Empadinhas, N.]]
	[[Category: Macedo-Ribeiro, S.]]		[[Category: Macedo-Ribeiro, S.]]
	[[Category: Pereira, P J.B.]]		[[Category: Pereira, P J.B.]]
		+	[[Category: Gdp-mannose]]
		+	[[Category: Glycosyltransferase]]
		+	[[Category: Gt-81]]
		+	[[Category: Gt-a type glycosyltransferase]]
		+	[[Category: Mannosyl-3-phosphoglycerate synthase]]
		+	[[Category: Rubrobacter xylanophilus]]
		+	[[Category: Transferase]]

OCA: Protected "3kia" [edit=sysop:move=sysop]

2011-01-05T15:36:51Z

Protected "3kia" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:36, 5 January 2011

OCA at 15:36, 5 January 2011

2011-01-05T15:36:49Z

←Older revision		Revision as of 15:36, 5 January 2011
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-	~~{{Seed}}~~	+	[[Image:3kia.png\|left\|200px]]
-	[[Image:3kia.~~jpg~~\|left\|200px]]	+

	<!--		<!--
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	===Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus===		===Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21166895}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21166895 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21166895}}

	==About this Structure==		==About this Structure==
-	~~3KIA~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Rubrobacter_xylanophilus_dsm_9941 Rubrobacter xylanophilus dsm 9941]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA].	+	[[3kia]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rubrobacter_xylanophilus_dsm_9941 Rubrobacter xylanophilus dsm 9941]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:21166895</ref><references group="xtra"/>
	[[Category: Mannosyl-3-phosphoglycerate synthase]]		[[Category: Mannosyl-3-phosphoglycerate synthase]]
	[[Category: Rubrobacter xylanophilus dsm 9941]]		[[Category: Rubrobacter xylanophilus dsm 9941]]
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	[[Category: Macedo-Ribeiro, S.]]		[[Category: Macedo-Ribeiro, S.]]
	[[Category: Pereira, P J.B.]]		[[Category: Pereira, P J.B.]]
-	[[Category: Gdp-mannose]]
-	[[Category: Glycosyltransferase]]
-	[[Category: Gt-81]]
-	[[Category: Gt-a type glycosyltransferase]]
-	[[Category: Mannosyl-3-phosphoglycerate synthase]]
-	[[Category: Rubrobacter xylanophilus]]
-	[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 3 11:08:44 2010''

OCA at 07:58, 3 November 2010

2010-11-03T07:58:06Z

←Older revision		Revision as of 07:58, 3 November 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3kia.jpg\|left\|200px]]

-	The ~~entry 3kia~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3kia", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3kia\| PDB=3kia \| SCENE= }}

-	~~Authors: Macedo~~-~~Ribeiro, S., Pereira, P.J.B., Empadinhas, N., da Costa, M.S.~~	+	===Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus===

-	Description: Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Dec 23 09~~:22:~~13 2009~~''	+	==About this Structure==
		+	3KIA is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Rubrobacter_xylanophilus_dsm_9941 Rubrobacter xylanophilus dsm 9941]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KIA OCA].
		+	[[Category: Mannosyl-3-phosphoglycerate synthase]]
		+	[[Category: Rubrobacter xylanophilus dsm 9941]]
		+	[[Category: Costa, M S.da.]]
		+	[[Category: Empadinhas, N.]]
		+	[[Category: Macedo-Ribeiro, S.]]
		+	[[Category: Pereira, P J.B.]]
		+	[[Category: Gdp-mannose]]
		+	[[Category: Glycosyltransferase]]
		+	[[Category: Gt-81]]
		+	[[Category: Gt-a type glycosyltransferase]]
		+	[[Category: Mannosyl-3-phosphoglycerate synthase]]
		+	[[Category: Rubrobacter xylanophilus]]
		+	[[Category: Transferase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 3 11:08:44 2010''