3kp5 - Revision history

OCA at 16:15, 1 November 2023

2023-11-01T16:15:54Z

←Older revision		Revision as of 16:15, 1 November 2023
Line 1:		Line 1:

	==Staphylococcus epidermidis TcaR in complex with kanamycin==		==Staphylococcus epidermidis TcaR in complex with kanamycin==
-	<StructureSection load='3kp5' size='340' side='right' caption='[[3kp5]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='3kp5' size='340' side='right'caption='[[3kp5]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kp5]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Staeq Staeq~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KP5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3KP5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kp5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_epidermidis_RP62A Staphylococcus epidermidis RP62A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KP5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KP5 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kp2\|3kp2]]~~, [[~~3kp3~~\|~~3kp3]], [[3kp4\|3kp4]], [[3kp6\|3kp6]], [[3kp7\|3kp7~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~SERP1949, SE_1937, tcaR ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=176279 STAEQ])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kp5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kp5 OCA], [https://pdbe.org/3kp5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kp5 RCSB], [https://www.ebi.ac.uk/pdbsum/3kp5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kp5 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3kp5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kp5 OCA], [~~http~~://pdbe.org/3kp5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3kp5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3kp5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3kp5 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q5HLN6_STAEQ Q5HLN6_STAEQ]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Staeq~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Chang, Y M~~]]	+	[[Category: Staphylococcus epidermidis RP62A]]
-	[[Category: ~~Chen, C K~~]]	+	[[Category: Chang YM]]
-	[[Category: ~~Wang, A H~~]]	+	[[Category: Chen CK]]
-	[[Category: ~~Antibiotic]]~~	+	[[Category: Wang AH]]
-	~~[[Category: Biofilm]]~~	+
-	~~[[Category: Dna binding]]~~	+
-	~~[[Category: Multiple drug resistance]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Transcription regulation]]~~	+
-	~~[[Category: Transcription regulator-antibiotic complex~~]]	+

OCA at 09:48, 26 December 2018

2018-12-26T09:48:55Z

←Older revision		Revision as of 09:48, 26 December 2018
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kp/3kp5_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kp/3kp5_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 20:02, 4 August 2016

2016-08-04T20:02:53Z

←Older revision		Revision as of 20:02, 4 August 2016
Line 1:		Line 1:
		+
	==Staphylococcus epidermidis TcaR in complex with kanamycin==		==Staphylococcus epidermidis TcaR in complex with kanamycin==
	<StructureSection load='3kp5' size='340' side='right' caption='[[3kp5]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3kp5' size='340' side='right' caption='[[3kp5]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kp5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Staphylococcus_epidermidis_rp62a Staphylococcus epidermidis rp62a~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KP5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KP5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kp5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staeq Staeq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KP5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KP5 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kp2\|3kp2]], [[3kp3\|3kp3]], [[3kp4\|3kp4]], [[3kp6\|3kp6]], [[3kp7\|3kp7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kp2\|3kp2]], [[3kp3\|3kp3]], [[3kp4\|3kp4]], [[3kp6\|3kp6]], [[3kp7\|3kp7]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SERP1949, SE_1937, tcaR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=176279 ~~Staphylococcus epidermidis RP62A~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SERP1949, SE_1937, tcaR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=176279 STAEQ])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kp5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kp5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kp5 RCSB], [http://www.ebi.ac.uk/pdbsum/3kp5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kp5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kp5 OCA], [http://pdbe.org/3kp5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kp5 RCSB], [http://www.ebi.ac.uk/pdbsum/3kp5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kp5 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kp5 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3kp5" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Staphylococcus epidermidis rp62a~~]]	+	[[Category: Staeq]]
	[[Category: Chang, Y M]]		[[Category: Chang, Y M]]
	[[Category: Chen, C K]]		[[Category: Chen, C K]]

OCA at 17:21, 18 December 2014

2014-12-18T17:21:33Z

←Older revision		Revision as of 17:21, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3kp5~~\| ~~PDB~~=3kp5 \| ~~SCENE~~= }}	+	==Staphylococcus epidermidis TcaR in complex with kanamycin==
-	===Staphylococcus epidermidis ~~TcaR in complex with kanamycin~~===	+	<StructureSection load='3kp5' size='340' side='right' caption='[[3kp5]], [[Resolution\|resolution]] 3.00Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20421503}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3kp5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_epidermidis_rp62a Staphylococcus epidermidis rp62a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KP5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KP5 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kp2\|3kp2]], [[3kp3\|3kp3]], [[3kp4\|3kp4]], [[3kp6\|3kp6]], [[3kp7\|3kp7]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SERP1949, SE_1937, tcaR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=176279 Staphylococcus epidermidis RP62A])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kp5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kp5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kp5 RCSB], [http://www.ebi.ac.uk/pdbsum/3kp5 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kp/3kp5_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	TcaR and IcaR are a weak and a strong negative regulator of transcription of the ica locus, respectively, and their presence prevents the poly-N-acetylglucosamine production and biofilm formation in Staphylococcus epidermidis. Although TcaR was shown to interact with the ica promoter, the precise binding region and the mechanism of interaction remained unclear. Here we present the 3D structure of TcaR in its apo form and in complex with salicylate as well as several aminoglycoside and beta-lactam antibiotics. A comparison of the native and complex TcaR structures indicates that the mechanism of regulation involves a large conformational change in the DNA-binding lobe. Here, we deduced the consensus binding sequence of two [ approximately TTNNAA] hexamers embedded in a 16 bp sequence for a TcaR dimer. Six TcaR dimers bind specifically to three approximately 33 bp segments close to the IcaR binding region with varying affinities, and their repressor activity is directly interfered by salicylate and different classes of natural antimicrobial compounds. We also found in this study that the antimicrobial compounds we tested were shown not only to inhibit TcaR-DNA interaction but also to further induce biofilm formation in S. epidermidis in our in vivo assay. The results support a general mechanism for antibiotics in regulating TcaR-DNA interaction and thereby help understand the effect of antibiotic exposure on bacterial antibiotic resistance through biofilm formation.

-	~~==About this Structure==~~	+	Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis.,Chang YM, Jeng WY, Ko TP, Yeh YJ, Chen CK, Wang AH Proc Natl Acad Sci U S A. 2010 May 11;107(19):8617-22. Epub 2010 Apr 26. PMID:20421503<ref>PMID:20421503</ref>
-	~~[[3kp5]] is a 2 chain structure~~ with ~~sequence~~ from ~~[http://en.wikipedia.org/wiki/Staphylococcus_epidermidis_rp62a~~ Staphylococcus epidermidis ~~rp62a]~~. ~~Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3KP5 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:020421503</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Staphylococcus epidermidis rp62a]]		[[Category: Staphylococcus epidermidis rp62a]]
-	[[Category: Chang, Y M.]]	+	[[Category: Chang, Y M]]
-	[[Category: Chen, C K.]]	+	[[Category: Chen, C K]]
-	[[Category: Wang, A H.]]	+	[[Category: Wang, A H]]
	[[Category: Antibiotic]]		[[Category: Antibiotic]]
	[[Category: Biofilm]]		[[Category: Biofilm]]

OCA at 02:49, 4 April 2013

2013-04-04T02:49:39Z

←Older revision		Revision as of 02:49, 4 April 2013
Line 1:		Line 1:
-	[[Image:3kp5.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3kp5", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3kp5\| PDB=3kp5 \| SCENE= }}		{{STRUCTURE_3kp5\| PDB=3kp5 \| SCENE= }}
-
	===Staphylococcus epidermidis TcaR in complex with kanamycin===		===Staphylococcus epidermidis TcaR in complex with kanamycin===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20421503}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20421503 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20421503}}		{{ABSTRACT_PUBMED_20421503}}

Line 22:		Line 7:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20421503~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020421503</ref><references group="xtra"/><references/>
	[[Category: Staphylococcus epidermidis rp62a]]		[[Category: Staphylococcus epidermidis rp62a]]
	[[Category: Chang, Y M.]]		[[Category: Chang, Y M.]]

OCA: Protected "3kp5" [edit=sysop:move=sysop]

2010-12-29T18:31:30Z

Protected "3kp5" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:31, 29 December 2010

OCA at 18:31, 29 December 2010

2010-12-29T18:31:29Z

←Older revision		Revision as of 18:31, 29 December 2010
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3kp5.png\|left\|200px]]		[[Image:3kp5.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~3KP5~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Staphylococcus_epidermidis_rp62a Staphylococcus epidermidis rp62a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KP5 OCA].	+	[[3kp5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_epidermidis_rp62a Staphylococcus epidermidis rp62a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KP5 OCA].

	==Reference==		==Reference==
Line 35:		Line 34:
	[[Category: Transcription regulation]]		[[Category: Transcription regulation]]
	[[Category: Transcription regulator-antibiotic complex]]		[[Category: Transcription regulator-antibiotic complex]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:35:01 2010''

OCA at 04:30, 16 June 2010

2010-06-16T04:30:00Z

←Older revision		Revision as of 04:30, 16 June 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3kp5.~~jpg~~\|left\|200px]]	+	[[Image:3kp5.png\|left\|200px]]

	<!--		<!--
Line 36:		Line 36:
	[[Category: Transcription regulator-antibiotic complex]]		[[Category: Transcription regulator-antibiotic complex]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu~~ Jun ~~10 11~~:10:11 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:35:01 2010''

OCA at 07:05, 10 June 2010

2010-06-10T07:05:25Z

←Older revision		Revision as of 07:05, 10 June 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3kp5.jpg\|left\|200px]]

-	The ~~entry 3kp5~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3kp5", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3kp5\| PDB=3kp5 \| SCENE= }}

-	~~Authors: Chang, Y.M., Chen, C.K.-M., Wang, A.H.-J.~~	+	===Staphylococcus epidermidis TcaR in complex with kanamycin===

-	Description: Staphylococcus epidermidis TcaR in complex with kanamycin

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Dec 9 14~~:43:~~52 2009~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20421503}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20421503 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20421503}}
		+
		+	==About this Structure==
		+	3KP5 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Staphylococcus_epidermidis_rp62a Staphylococcus epidermidis rp62a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KP5 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20421503</ref><references group="xtra"/>
		+	[[Category: Staphylococcus epidermidis rp62a]]
		+	[[Category: Chang, Y M.]]
		+	[[Category: Chen, C K.]]
		+	[[Category: Wang, A H.]]
		+	[[Category: Antibiotic]]
		+	[[Category: Biofilm]]
		+	[[Category: Dna binding]]
		+	[[Category: Multiple drug resistance]]
		+	[[Category: Transcription]]
		+	[[Category: Transcription regulation]]
		+	[[Category: Transcription regulator-antibiotic complex]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 10 11:10:11 2010''

OCA at 12:43, 9 December 2009

2009-12-09T12:43:52Z

←Older revision		Revision as of 12:43, 9 December 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3kp5 is ON HOLD	+	The entry 3kp5 is ON HOLD until Paper Publication

	Authors: Chang, Y.M., Chen, C.K.-M., Wang, A.H.-J.		Authors: Chang, Y.M., Chen, C.K.-M., Wang, A.H.-J.
Line 7:		Line 7:
	Description: Staphylococcus epidermidis TcaR in complex with kanamycin		Description: Staphylococcus epidermidis TcaR in complex with kanamycin

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Nov 25 09:~~14:10 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 14:43:52 2009''