3lz2 - Revision history

OCA at 11:16, 17 July 2019

2019-07-17T11:16:05Z

←Older revision		Revision as of 11:16, 17 July 2019
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	==STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION==		==STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION==
-	<StructureSection load='3lz2' size='340' side='right' caption='[[3lz2]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='3lz2' size='340' side='right'caption='[[3lz2]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3lz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Melga Melga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LZ2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3lz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Melga Melga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LZ2 FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lz/3lz2_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lz/3lz2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Melga]]		[[Category: Melga]]

OCA at 07:15, 29 November 2017

2017-11-29T07:15:44Z

←Older revision		Revision as of 07:15, 29 November 2017
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	<StructureSection load='3lz2' size='340' side='right' caption='[[3lz2]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3lz2' size='340' side='right' caption='[[3lz2]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3lz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Common_turkey Common turkey~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LZ2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3lz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Melga Melga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LZ2 FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lz2 OCA], [http://pdbe.org/3lz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lz2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lz2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lz2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lz2 OCA], [http://pdbe.org/3lz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lz2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lz2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lz2 ProSAT]</span></td></tr>
Line 35:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Common turkey]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
		+	[[Category: Melga]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]
	[[Category: Hajdu, J]]		[[Category: Hajdu, J]]

OCA at 15:38, 5 August 2016

2016-08-05T15:38:50Z

←Older revision		Revision as of 15:38, 5 August 2016
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		+
	==STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION==		==STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION==
	<StructureSection load='3lz2' size='340' side='right' caption='[[3lz2]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3lz2' size='340' side='right' caption='[[3lz2]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3lz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Meleagris_gallopavo Meleagris gallopavo~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LZ2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3lz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Common_turkey Common turkey]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LZ2 FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lz2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lz2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lz2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lz2 OCA], [http://pdbe.org/3lz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lz2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lz2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lz2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lz2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3lz2" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Common turkey]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
-	[[Category: Meleagris gallopavo]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]
	[[Category: Hajdu, J]]		[[Category: Hajdu, J]]

OCA at 19:58, 25 December 2014

2014-12-25T19:58:24Z

←Older revision		Revision as of 19:58, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3lz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LZ2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3lz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LZ2 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lz2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lz2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lz2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lz2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lz2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lz2 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LYSC_MELGA LYSC_MELGA]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Meleagris gallopavo]]		[[Category: Meleagris gallopavo]]
-	[[Category: Almo, S C.]]	+	[[Category: Almo, S C]]
-	[[Category: Hajdu, J.]]	+	[[Category: Hajdu, J]]
-	[[Category: Howell, P L.]]	+	[[Category: Howell, P L]]
-	[[Category: Parsons, M R.]]	+	[[Category: Parsons, M R]]
-	[[Category: Petsko, G A.]]	+	[[Category: Petsko, G A]]

OCA at 12:07, 29 September 2014

2014-09-29T12:07:53Z

←Older revision		Revision as of 12:07, 29 September 2014
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-	[[~~Image~~:3lz2.~~png\|left~~\|200px]]	+	==STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION==
		+	<StructureSection load='3lz2' size='340' side='right' caption='[[3lz2]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3lz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LZ2 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lz2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lz2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lz2 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lz/3lz2_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The three-dimensional structure of turkey egg-white lysozyme (TEWL) has been solved and refined at 2.5 A resolution using X-ray data collected by the Laue method. This is the first protein structure determination undertaken using Laue diffraction data. A re-examination of the existing structure of TEWL was necessary when attempts to refine an atomic model based on the C alpha positions in the Protein Data Bank (entry 1LZ2) failed. The correct orientation and position of the turkey lysozyme molecules within the crystallographic unit cell were determined by molecular replacement using a refined model of the homologous hen egg-white lysozyme crystal structure. After modification of the model to reflect the differences in amino-acid sequence between the chicken and turkey enzymes, the structure was subjected to crystallographic refinement using the simulated-annealing refinement technique and conventional least-squares refinement. This yielded a final residual of R = 20.7%. This crystal form is of potential interest for time-resolved crystallographic studies since the amino-acid residues involved in catalysis (Asp52 and Glu35) are accessible to solvent and not blocked by crystal contacts.

-	~~{{STRUCTURE_3lz2\| PDB=3lz2 \| SCENE= }}~~	+	Structure determination of turkey egg-white lysozyme using Laue diffraction data.,Howell PL, Almo SC, Parsons MR, Hajdu J, Petsko GA Acta Crystallogr B. 1992 Apr 1;48 ( Pt 2):200-7. PMID:1515108<ref>PMID:1515108</ref>

-	~~===STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_1515108}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3lz2]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Meleagris_gallopavo Meleagris gallopavo]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA].~~	+

	==See Also==		==See Also==
-	*[[~~Hen Egg-White (HEW)~~ Lysozyme\|~~Hen Egg-White (HEW)~~ Lysozyme]]	+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:001515108<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Meleagris gallopavo]]		[[Category: Meleagris gallopavo]]

OCA at 20:50, 20 October 2012

2012-10-20T20:50:45Z

←Older revision		Revision as of 20:50, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3lz2]] is a 1 chain structure ~~of [[Hen Egg-White (HEW) Lysozyme]]~~ with sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA].	+	[[3lz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA].

	==See Also==		==See Also==

OCA: Protected "3lz2" [edit=sysop:move=sysop]

2012-07-27T11:48:08Z

Protected "3lz2" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:48, 27 July 2012

OCA at 11:48, 27 July 2012

2012-07-27T11:48:06Z

←Older revision		Revision as of 11:48, 27 July 2012
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-	{{Seed}}
	[[Image:3lz2.png\|left\|200px]]		[[Image:3lz2.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3lz2", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3lz2\| PDB=3lz2 \| SCENE= }}		{{STRUCTURE_3lz2\| PDB=3lz2 \| SCENE= }}

	===STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION===		===STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_1515108}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 1515108 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_1515108}}		{{ABSTRACT_PUBMED_1515108}}

	==About this Structure==		==About this Structure==
-	~~3LZ2~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA].	+	[[3lz2]] is a 1 chain structure of [[Hen Egg-White (HEW) Lysozyme]] with sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA].
		+
		+	==See Also==
		+	*[[Hen Egg-White (HEW) Lysozyme\|Hen Egg-White (HEW) Lysozyme]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~1515108~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:001515108</ref><references group="xtra"/>
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Meleagris gallopavo]]		[[Category: Meleagris gallopavo]]
Line 31:		Line 22:
	[[Category: Parsons, M R.]]		[[Category: Parsons, M R.]]
	[[Category: Petsko, G A.]]		[[Category: Petsko, G A.]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:26:07 2009''

OCA at 03:26, 18 February 2009

2009-02-18T03:26:08Z

←Older revision		Revision as of 03:26, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	3LZ2 is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA].	+	3LZ2 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ2 OCA].

	==Reference==		==Reference==
-	~~Structure determination of turkey egg-white lysozyme using Laue diffraction data., Howell PL, Almo SC, Parsons MR, Hajdu J, Petsko GA, Acta Crystallogr B. 1992 Apr 1;48 ( Pt 2):200-7.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/1515108 1515108]~~	+	<ref group="xtra">PMID:1515108</ref><references group="xtra"/>
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Meleagris gallopavo]]		[[Category: Meleagris gallopavo]]
-	[[Category: Single protein]]
	[[Category: Almo, S C.]]		[[Category: Almo, S C.]]
	[[Category: Hajdu, J.]]		[[Category: Hajdu, J.]]
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	[[Category: Petsko, G A.]]		[[Category: Petsko, G A.]]

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OCA at 09:54, 3 July 2008

2008-07-03T09:54:32Z

←Older revision		Revision as of 09:54, 3 July 2008
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	<!--		<!--
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	{{STRUCTURE_3lz2\| PDB=3lz2 \| SCENE= }}		{{STRUCTURE_3lz2\| PDB=3lz2 \| SCENE= }}

-	~~'''~~STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION~~'''~~	+	===STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION===


-	~~==Overview==~~	+	<!--
-	The ~~three-dimensional structure of turkey egg-white lysozyme (TEWL) has been solved and refined at 2.5 A resolution using X-ray data collected by~~ the ~~Laue method. This is the first protein structure determination undertaken using Laue diffraction data. A re-examination of the existing structure of TEWL was necessary when attempts~~ to ~~refine an atomic model based on~~ the ~~C alpha positions in the Protein Data Bank~~ (~~entry 1LZ2) failed~~. The correct orientation and position of the turkey lysozyme molecules within the crystallographic unit cell were determined by molecular replacement using a refined model of the homologous hen egg-white lysozyme crystal structure. ~~After modification of the model to reflect the differences in amino-acid sequence between the chicken and turkey enzymes~~, the ~~structure was subjected to crystallographic refinement using the simulated-annealing refinement technique and conventional least-squares refinement~~. ~~This yielded a final residual of R = 20.7%. This crystal form is of potential interest for time~~-~~resolved crystallographic studies since the amino~~-~~acid residues involved in catalysis (Asp52 and Glu35) are accessible to solvent and not blocked by crystal contacts.~~	+	The line below this paragraph, {{ABSTRACT_PUBMED_1515108}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 1515108 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_1515108}}

	==About this Structure==		==About this Structure==
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	[[Category: Parsons, M R.]]		[[Category: Parsons, M R.]]
	[[Category: Petsko, G A.]]		[[Category: Petsko, G A.]]
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