3m4u - Revision history

OCA at 10:24, 21 February 2024

2024-02-21T10:24:03Z

←Older revision		Revision as of 10:24, 21 February 2024
Line 1:		Line 1:

	==Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1==		==Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1==
-	<StructureSection load='3m4u' size='340' side='right' caption='[[3m4u]], [[Resolution\|resolution]] 2.39Å' scene=''>	+	<StructureSection load='3m4u' size='340' side='right'caption='[[3m4u]], [[Resolution\|resolution]] 2.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3m4u]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Trypanosoma_(trypanozoon)_brucei~~ Trypanosoma ~~(trypanozoon)~~ brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4U OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3M4U FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3m4u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M4U FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.392Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">Tb10~~.~~70.0070 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=5691 Trypanosoma (Trypanozoon) brucei])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]~~ </~~span~~></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m4u OCA], [https://pdbe.org/3m4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m4u RCSB], [https://www.ebi.ac.uk/pdbsum/3m4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m4u ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3m4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m4u OCA], [~~http~~://pdbe.org/3m4u PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3m4u RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3m4u PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3m4u ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q38AT7_TRYB2 Q38AT7_TRYB2]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m4/3m4u_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m4/3m4u_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 19:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m4u ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m4u ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Trypanosoma brucei adapts to changing environments as it cycles through arrested and proliferating stages in the human and tsetse fly hosts. Changes in protein tyrosine phosphorylation of several proteins, including NOPP44/46, accompany T. brucei development. Moreover, inactivation of T. brucei protein-tyrosine phosphatase 1 (TbPTP1) triggers differentiation of bloodstream stumpy forms into tsetse procyclic forms through unknown downstream effects. Here, we link these events by showing that NOPP44/46 is a major substrate of TbPTP1. TbPTP1 substrate-trapping mutants selectively enrich NOPP44/46 from procyclic stage cell lysates, and TbPTP1 efficiently and selectively dephosphorylates NOPP44/46 in vitro. To provide insights into the mechanism of NOPP44/46 recognition, we determined the crystal structure of TbPTP1. The TbPTP1 structure, the first of a kinetoplastid protein-tyrosine phosphatase (PTP), emphasizes the conservation of the PTP fold, extending to one of the most diverged eukaryotes. The structure reveals surfaces that may mediate substrate specificity and affords a template for the design of selective inhibitors to interfere with T. brucei transmission.
-
-	The Trypanosoma brucei life cycle switch TbPTP1 is structurally conserved and dephosphorylates the nucleolar protein NOPP44/46.,Chou S, Jensen BC, Parsons M, Alber T, Grundner C J Biol Chem. 2010 Jul 16;285(29):22075-81. Epub 2010 May 5. PMID:20444707<ref>PMID:20444707</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3m4u" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Protein-tyrosine-phosphatase~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Alber, T~~]]	+	[[Category: Trypanosoma brucei]]
-	[[Category: ~~Chou, S~~]]	+	[[Category: Alber T]]
-	[[Category: ~~Grundner, C~~]]	+	[[Category: Chou S]]
-	[[Category: ~~Hydrolase]]~~	+	[[Category: Grundner C]]
-	~~[[Category: Protein phosphatase]]~~	+
-	~~[[Category: Protein tyrosine phosphatase~~]]	+

OCA at 21:36, 5 August 2016

2016-08-05T21:36:25Z

←Older revision		Revision as of 21:36, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1==		==Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1==
	<StructureSection load='3m4u' size='340' side='right' caption='[[3m4u]], [[Resolution\|resolution]] 2.39Å' scene=''>		<StructureSection load='3m4u' size='340' side='right' caption='[[3m4u]], [[Resolution\|resolution]] 2.39Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3m4u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Trypanosoma_brucei~~ Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M4U FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3m4u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_(trypanozoon)_brucei Trypanosoma (trypanozoon) brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M4U FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tb10.70.0070 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma brucei])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tb10.70.0070 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma (Trypanozoon) brucei])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m4u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3m4u RCSB], [http://www.ebi.ac.uk/pdbsum/3m4u PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m4u OCA], [http://pdbe.org/3m4u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3m4u RCSB], [http://www.ebi.ac.uk/pdbsum/3m4u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3m4u ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m4u ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3m4u" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Protein-tyrosine-phosphatase]]		[[Category: Protein-tyrosine-phosphatase]]
-	[[Category: Trypanosoma brucei]]
	[[Category: Alber, T]]		[[Category: Alber, T]]
	[[Category: Chou, S]]		[[Category: Chou, S]]

OCA at 17:00, 18 December 2014

2014-12-18T17:00:10Z

←Older revision		Revision as of 17:00, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3m4u~~\| ~~PDB~~=3m4u \| ~~SCENE~~= }}	+	==Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1==
-	===~~Crystal Structure of~~ Trypanosoma brucei Protein ~~Tyrosine Phosphatase TbPTP1~~===	+	<StructureSection load='3m4u' size='340' side='right' caption='[[3m4u]], [[Resolution\|resolution]] 2.39Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20444707}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3m4u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M4U FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tb10.70.0070 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma brucei])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m4u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3m4u RCSB], [http://www.ebi.ac.uk/pdbsum/3m4u PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m4/3m4u_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Trypanosoma brucei adapts to changing environments as it cycles through arrested and proliferating stages in the human and tsetse fly hosts. Changes in protein tyrosine phosphorylation of several proteins, including NOPP44/46, accompany T. brucei development. Moreover, inactivation of T. brucei protein-tyrosine phosphatase 1 (TbPTP1) triggers differentiation of bloodstream stumpy forms into tsetse procyclic forms through unknown downstream effects. Here, we link these events by showing that NOPP44/46 is a major substrate of TbPTP1. TbPTP1 substrate-trapping mutants selectively enrich NOPP44/46 from procyclic stage cell lysates, and TbPTP1 efficiently and selectively dephosphorylates NOPP44/46 in vitro. To provide insights into the mechanism of NOPP44/46 recognition, we determined the crystal structure of TbPTP1. The TbPTP1 structure, the first of a kinetoplastid protein-tyrosine phosphatase (PTP), emphasizes the conservation of the PTP fold, extending to one of the most diverged eukaryotes. The structure reveals surfaces that may mediate substrate specificity and affords a template for the design of selective inhibitors to interfere with T. brucei transmission.

-	~~==About this Structure==~~	+	The Trypanosoma brucei life cycle switch TbPTP1 is structurally conserved and dephosphorylates the nucleolar protein NOPP44/46.,Chou S, Jensen BC, Parsons M, Alber T, Grundner C J Biol Chem. 2010 Jul 16;285(29):22075-81. Epub 2010 May 5. PMID:20444707<ref>PMID:20444707</ref>
-	~~[[3m4u]]~~ is ~~a 2 chain structure with sequence from [http:~~/~~/en~~.~~wikipedia~~.~~org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3M4U OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:020444707</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Protein-tyrosine-phosphatase]]		[[Category: Protein-tyrosine-phosphatase]]
	[[Category: Trypanosoma brucei]]		[[Category: Trypanosoma brucei]]
-	[[Category: Alber, T.]]	+	[[Category: Alber, T]]
-	[[Category: Chou, S.]]	+	[[Category: Chou, S]]
-	[[Category: Grundner, C.]]	+	[[Category: Grundner, C]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Protein phosphatase]]		[[Category: Protein phosphatase]]
	[[Category: Protein tyrosine phosphatase]]		[[Category: Protein tyrosine phosphatase]]

OCA: Protected "3m4u" [edit=sysop:move=sysop]

2013-04-10T23:03:52Z

Protected "3m4u" [edit=sysop:move=sysop]

←Older revision

Revision as of 23:03, 10 April 2013

OCA at 23:03, 10 April 2013

2013-04-10T23:03:49Z

←Older revision		Revision as of 23:03, 10 April 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3m4u.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3m4u", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3m4u\| PDB=3m4u \| SCENE= }}		{{STRUCTURE_3m4u\| PDB=3m4u \| SCENE= }}
-
	===Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1===		===Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20444707}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20444707 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20444707}}		{{ABSTRACT_PUBMED_20444707}}

	==About this Structure==		==About this Structure==
-	~~3M4U~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4U OCA].	+	[[3m4u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4U OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20444707~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020444707</ref><references group="xtra"/><references/>
	[[Category: Protein-tyrosine-phosphatase]]		[[Category: Protein-tyrosine-phosphatase]]
	[[Category: Trypanosoma brucei]]		[[Category: Trypanosoma brucei]]
Line 32:		Line 16:
	[[Category: Protein phosphatase]]		[[Category: Protein phosphatase]]
	[[Category: Protein tyrosine phosphatase]]		[[Category: Protein tyrosine phosphatase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:14:08 2010''

OCA at 05:06, 1 September 2010

2010-09-01T05:06:00Z

←Older revision		Revision as of 05:06, 1 September 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3m4u.~~jpg~~\|left\|200px]]	+	[[Image:3m4u.png\|left\|200px]]

	<!--		<!--
Line 12:		Line 12:
	===Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1===		===Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20444707}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20444707 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20444707}}

	==About this Structure==		==About this Structure==
	3M4U is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4U OCA].		3M4U is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4U OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20444707</ref><references group="xtra"/>
	[[Category: Protein-tyrosine-phosphatase]]		[[Category: Protein-tyrosine-phosphatase]]
	[[Category: Trypanosoma brucei]]		[[Category: Trypanosoma brucei]]
Line 24:		Line 33:
	[[Category: Protein tyrosine phosphatase]]		[[Category: Protein tyrosine phosphatase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~May~~ ~~5 12~~:10:57 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:14:08 2010''

OCA at 09:10, 5 May 2010

2010-05-05T09:10:58Z

←Older revision		Revision as of 09:10, 5 May 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3m4u.jpg\|left\|200px]]

-	The ~~entry 3m4u~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3m4u", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3m4u\| PDB=3m4u \| SCENE= }}

-	~~Authors: Chou, S., Alber, T., Grundner, C.~~	+	===Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1===

-	Description: Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Mar 31 13~~:22:45 2010''	+	==About this Structure==
		+	3M4U is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4U OCA].
		+	[[Category: Protein-tyrosine-phosphatase]]
		+	[[Category: Trypanosoma brucei]]
		+	[[Category: Alber, T.]]
		+	[[Category: Chou, S.]]
		+	[[Category: Grundner, C.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Protein phosphatase]]
		+	[[Category: Protein tyrosine phosphatase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 12:10:57 2010''

OCA at 10:22, 31 March 2010

2010-03-31T10:22:45Z

←Older revision		Revision as of 10:22, 31 March 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3m4u is ON HOLD	+	The entry 3m4u is ON HOLD until Paper Publication

	Authors: Chou, S., Alber, T., Grundner, C.		Authors: Chou, S., Alber, T., Grundner, C.
Line 7:		Line 7:
	Description: Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1		Description: Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar ~~24 08~~:38:23 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 13:22:45 2010''

OCA at 06:38, 24 March 2010

2010-03-24T06:38:23Z

←Older revision		Revision as of 06:38, 24 March 2010
Line 3:		Line 3:
	The entry 3m4u is ON HOLD		The entry 3m4u is ON HOLD

-	Authors: Chou, S~~., Jensen, B., Parsons, M~~., Alber, T., Grundner, C.	+	Authors: Chou, S., Alber, T., Grundner, C.

	Description: Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1		Description: Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar ~~17 09~~:13:51 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 24 08:38:23 2010''

OCA: New page: '''Unreleased structure''' The entry 3m4u is ON HOLD Authors: Chou, S., Jensen, B., Parsons, M., Alber, T., Grundner, C. Description: Crystal Structure of Trypanosoma brucei Protein Ty...

2010-03-17T07:13:51Z

New page: '''Unreleased structure''' The entry 3m4u is ON HOLD Authors: Chou, S., Jensen, B., Parsons, M., Alber, T., Grundner, C. Description: Crystal Structure of Trypanosoma brucei Protein Ty...

New page

'''Unreleased structure'''

The entry 3m4u is ON HOLD

Authors: Chou, S., Jensen, B., Parsons, M., Alber, T., Grundner, C.

Description: Crystal Structure of Trypanosoma brucei Protein Tyrosine Phosphatase TbPTP1

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:13:51 2010''