3mcy - Revision history

OCA at 08:51, 6 September 2023

2023-09-06T08:51:38Z

←Older revision		Revision as of 08:51, 6 September 2023
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	<StructureSection load='3mcy' size='340' side='right'caption='[[3mcy]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='3mcy' size='340' side='right'caption='[[3mcy]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mcy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MCY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mcy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MCY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZH1:METHYL+4-(ALPHA-D-MANNOPYRANOSYLOXY)BIPHENYL-3-CARBOXYLATE'>ZH1</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fimH ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZH1:METHYL+4-(ALPHA-D-MANNOPYRANOSYLOXY)BIPHENYL-3-CARBOXYLATE'>ZH1</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mcy OCA], [https://pdbe.org/3mcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mcy RCSB], [https://www.ebi.ac.uk/pdbsum/3mcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mcy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mcy OCA], [https://pdbe.org/3mcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mcy RCSB], [https://www.ebi.ac.uk/pdbsum/3mcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mcy ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9S497_ECOLX Q9S497_ECOLX]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ford~~, B A~~]]	+	[[Category: Ford BA]]
-	[[Category: Hultgren~~, S J]]~~	+	[[Category: Hultgren SJ]]
-	~~[[Category: Carbohydrate binding protein]]~~	+
-	~~[[Category: Immunogobulin fold]]~~	+
-	~~[[Category: Lectin]]~~	+
-	~~[[Category: Mannoside~~]]	+

OCA at 13:45, 4 May 2022

2022-05-04T13:45:53Z

←Older revision		Revision as of 13:45, 4 May 2022
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	==Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.==		==Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.==
-	<StructureSection load='3mcy' size='340' side='right' caption='[[3mcy]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='3mcy' size='340' side='right'caption='[[3mcy]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mcy]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3MCY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mcy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MCY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZH1:METHYL+4-(ALPHA-D-MANNOPYRANOSYLOXY)BIPHENYL-3-CARBOXYLATE'>ZH1</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZH1:METHYL+4-(ALPHA-D-MANNOPYRANOSYLOXY)BIPHENYL-3-CARBOXYLATE'>ZH1</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fimH ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fimH ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3mcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mcy OCA], [~~http~~://pdbe.org/3mcy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3mcy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3mcy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3mcy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mcy OCA], [https://pdbe.org/3mcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mcy RCSB], [https://www.ebi.ac.uk/pdbsum/3mcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mcy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Ford, B A]]		[[Category: Ford, B A]]
	[[Category: Hultgren, S J]]		[[Category: Hultgren, S J]]

OCA at 12:43, 5 August 2016

2016-08-05T12:43:34Z

←Older revision		Revision as of 12:43, 5 August 2016
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		+
	==Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.==		==Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.==
	<StructureSection load='3mcy' size='340' side='right' caption='[[3mcy]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='3mcy' size='340' side='right' caption='[[3mcy]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mcy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MCY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mcy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MCY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZH1:METHYL+4-(ALPHA-D-MANNOPYRANOSYLOXY)BIPHENYL-3-CARBOXYLATE'>ZH1</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZH1:METHYL+4-(ALPHA-D-MANNOPYRANOSYLOXY)BIPHENYL-3-CARBOXYLATE'>ZH1</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fimH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fimH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mcy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mcy RCSB], [http://www.ebi.ac.uk/pdbsum/3mcy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mcy OCA], [http://pdbe.org/3mcy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mcy RCSB], [http://www.ebi.ac.uk/pdbsum/3mcy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mcy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3mcy" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Ford, B A]]		[[Category: Ford, B A]]
	[[Category: Hultgren, S J]]		[[Category: Hultgren, S J]]

OCA at 17:55, 18 December 2014

2014-12-18T17:55:52Z

←Older revision		Revision as of 17:55, 18 December 2014
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-	~~{{STRUCTURE_3mcy\| PDB=3mcy \| SCENE= }}~~	+	==Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.==
-	===Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.===	+	<StructureSection load='3mcy' size='340' side='right' caption='[[3mcy]], [[Resolution\|resolution]] 2.90Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20507142}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3mcy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MCY FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZH1:METHYL+4-(ALPHA-D-MANNOPYRANOSYLOXY)BIPHENYL-3-CARBOXYLATE'>ZH1</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fimH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mcy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mcy RCSB], [http://www.ebi.ac.uk/pdbsum/3mcy PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	FimH-mediated cellular adhesion to mannosylated proteins is critical in the ability of uropathogenic E. coli (UPEC) to colonize and invade the bladder epithelium during urinary tract infection. We describe the discovery and optimization of potent small-molecule FimH bacterial adhesion antagonists based on alpha-d-mannose 1-position anomeric glycosides using X-ray structure-guided drug design. Optimized biarylmannosides display low nanomolar binding affinity for FimH in a fluorescence polarization assay and submicromolar cellular activity in a hemagglutination (HA) functional cell assay of bacterial adhesion. X-ray crystallography demonstrates that the biphenyl moiety makes several key interactions with the outer surface of FimH including pi-pi interactions with Tyr-48 and an H-bonding electrostatic interaction with the Arg-98/Glu-50 salt bridge. Dimeric analogues linked through the biaryl ring show an impressive 8-fold increase in potency relative to monomeric matched pairs and represent the most potent FimH antagonists identified to date. The FimH antagonists described herein hold great potential for development as novel therapeutics for the effective treatment of urinary tract infections.

-	~~==About this~~ Structure==	+	Structure-Based Drug Design and Optimization of Mannoside Bacterial FimH Antagonists.,Han Z, Pinkner JS, Ford B, Obermann R, Nolan W, Wildman SA, Hobbs D, Ellenberger T, Cusumano CK, Hultgren SJ, Janetka JW J Med Chem. 2010 May 27. PMID:20507142<ref>PMID:20507142</ref>
-	~~[[3mcy]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3MCY OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:020507142</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Ford, B A.]]	+	[[Category: Ford, B A]]
-	[[Category: Hultgren, S J.]]	+	[[Category: Hultgren, S J]]
	[[Category: Carbohydrate binding protein]]		[[Category: Carbohydrate binding protein]]
	[[Category: Immunogobulin fold]]		[[Category: Immunogobulin fold]]
	[[Category: Lectin]]		[[Category: Lectin]]
	[[Category: Mannoside]]		[[Category: Mannoside]]

OCA: Protected "3mcy" [edit=sysop:move=sysop]

2013-04-10T23:24:55Z

Protected "3mcy" [edit=sysop:move=sysop]

←Older revision

Revision as of 23:24, 10 April 2013

OCA at 23:24, 10 April 2013

2013-04-10T23:24:53Z

←Older revision		Revision as of 23:24, 10 April 2013
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-	{{Seed}}
-	[[Image:3mcy.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3mcy", creates the "Structure Box" on the page.
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-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3mcy\| PDB=3mcy \| SCENE= }}		{{STRUCTURE_3mcy\| PDB=3mcy \| SCENE= }}
-
	===Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.===		===Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20507142}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20507142 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_20507142}}		{{ABSTRACT_PUBMED_20507142}}

	==About this Structure==		==About this Structure==
-	~~3MCY~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCY OCA].	+	[[3mcy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCY OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20507142~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020507142</ref><references group="xtra"/><references/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Ford, B A.]]		[[Category: Ford, B A.]]
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	[[Category: Lectin]]		[[Category: Lectin]]
	[[Category: Mannoside]]		[[Category: Mannoside]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 09:54:05 2010''

OCA at 05:47, 21 July 2010

2010-07-21T05:47:39Z

←Older revision		Revision as of 05:47, 21 July 2010
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	{{Seed}}		{{Seed}}
-	[[Image:3mcy.~~jpg~~\|left\|200px]]	+	[[Image:3mcy.png\|left\|200px]]

	<!--		<!--
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	[[Category: Mannoside]]		[[Category: Mannoside]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 16 08~~:42:16 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 09:54:05 2010''

OCA at 04:37, 16 June 2010

2010-06-16T04:37:15Z

←Older revision		Revision as of 04:37, 16 June 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3mcy.jpg\|left\|200px]]

-	The ~~entry 3mcy~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3mcy", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3mcy\| PDB=3mcy \| SCENE= }}

-	~~Authors: Ford, B.A., Hultgren, S.J~~.	+	===Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.===

-	Description: Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~May 5 11~~:38:36 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20507142}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20507142 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20507142}}
		+
		+	==About this Structure==
		+	3MCY is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCY OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20507142</ref><references group="xtra"/>
		+	[[Category: Escherichia coli]]
		+	[[Category: Ford, B A.]]
		+	[[Category: Hultgren, S J.]]
		+	[[Category: Carbohydrate binding protein]]
		+	[[Category: Immunogobulin fold]]
		+	[[Category: Lectin]]
		+	[[Category: Mannoside]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:42:16 2010''

OCA at 08:38, 5 May 2010

2010-05-05T08:38:37Z

←Older revision		Revision as of 08:38, 5 May 2010
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3mcy is ON HOLD	+	The entry 3mcy is ON HOLD until Paper Publication

	Authors: Ford, B.A., Hultgren, S.J.		Authors: Ford, B.A., Hultgren, S.J.
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	Description: Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.		Description: Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Apr~~ ~~7 10~~:22:30 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 11:38:36 2010''

OCA: New page: '''Unreleased structure''' The entry 3mcy is ON HOLD Authors: Ford, B.A., Hultgren, S.J. Description: Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl es...

2010-04-07T07:22:31Z

New page: '''Unreleased structure''' The entry 3mcy is ON HOLD Authors: Ford, B.A., Hultgren, S.J. Description: Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl es...

New page

'''Unreleased structure'''

The entry 3mcy is ON HOLD

Authors: Ford, B.A., Hultgren, S.J.

Description: Crystal structure of FimH lectin domain bound to biphenyl mannoside meta-methyl ester.

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 7 10:22:30 2010''