3mlh - Revision history

OCA at 08:55, 6 September 2023

2023-09-06T08:55:31Z

←Older revision		Revision as of 08:55, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3mlh' size='340' side='right'caption='[[3mlh]], [[Resolution\|resolution]] 2.09Å' scene=''>		<StructureSection load='3mlh' size='340' side='right'caption='[[3mlh]], [[Resolution\|resolution]] 2.09Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mlh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Influenza_a_virus_~~(a/~~mexico~~/4603/2009(~~h1n1~~)) Influenza a virus (a/~~mexico~~/4603/2009(~~h1n1~~))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MLH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mlh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/Mexico/4603/2009(H1N1)) Influenza A virus (A/Mexico/4603/2009(H1N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MLH FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.09Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~HA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=644887 Influenza A virus (A~~/~~Mexico/4603/2009(H1N1))])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mlh OCA], [https://pdbe.org/3mlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mlh RCSB], [https://www.ebi.ac.uk/pdbsum/3mlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mlh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mlh OCA], [https://pdbe.org/3mlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mlh RCSB], [https://www.ebi.ac.uk/pdbsum/3mlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mlh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/C4RSQ3_9INFA C4RSQ3_9INFA]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.[RuleBase:RU003324][SAAS:SAAS00145386]	+	[https://www.uniprot.org/uniprot/C4RSQ3_9INFA C4RSQ3_9INFA] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.[RuleBase:RU003324][SAAS:SAAS00145386]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aguilar-Yanez~~, J M~~]]	+	[[Category: Aguilar-Yanez JM]]
-	[[Category: Alvarez~~, M M~~]]	+	[[Category: Alvarez MM]]
-	[[Category: DuBois~~, R M~~]]	+	[[Category: DuBois RM]]
-	[[Category: Mendoza-Ochoa~~, G I~~]]	+	[[Category: Mendoza-Ochoa GI]]
-	[[Category: Russell~~, C J~~]]	+	[[Category: Russell CJ]]
-	[[Category: Schultz-Cherry, S]]	+	[[Category: Schultz-Cherry S]]
-	[[Category: White~~, S W]]~~	+	[[Category: White SW]]
-	~~[[Category: Antigen]]~~	+
-	~~[[Category: Hemagglutinin]]~~	+
-	~~[[Category: Lectin]]~~	+
-	~~[[Category: Receptor-binding domain]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 13:48, 4 May 2022

2022-05-04T13:48:02Z

←Older revision		Revision as of 13:48, 4 May 2022
Line 1:		Line 1:

	==Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain==		==Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain==
-	<StructureSection load='3mlh' size='340' side='right' caption='[[3mlh]], [[Resolution\|resolution]] 2.09Å' scene=''>	+	<StructureSection load='3mlh' size='340' side='right'caption='[[3mlh]], [[Resolution\|resolution]] 2.09Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mlh]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Influenza_a_virus_(a/mexico/4603/2009(h1n1)) Influenza a virus (a/mexico/4603/2009(h1n1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3MLH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mlh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_a_virus_(a/mexico/4603/2009(h1n1)) Influenza a virus (a/mexico/4603/2009(h1n1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MLH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=644887 Influenza A virus (A/Mexico/4603/2009(H1N1))])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=644887 Influenza A virus (A/Mexico/4603/2009(H1N1))])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mlh OCA], [~~http~~://pdbe.org/3mlh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3mlh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3mlh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3mlh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mlh OCA], [https://pdbe.org/3mlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mlh RCSB], [https://www.ebi.ac.uk/pdbsum/3mlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mlh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/C4RSQ3_9INFA C4RSQ3_9INFA]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.[RuleBase:RU003324][SAAS:SAAS00145386]	+	[[https://www.uniprot.org/uniprot/C4RSQ3_9INFA C4RSQ3_9INFA]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.[RuleBase:RU003324][SAAS:SAAS00145386]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[Hemagglutinin\|Hemagglutinin]]	+	*[[Hemagglutinin 3D structures\|Hemagglutinin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Aguilar-Yanez, J M]]		[[Category: Aguilar-Yanez, J M]]
	[[Category: Alvarez, M M]]		[[Category: Alvarez, M M]]

OCA at 16:29, 5 August 2016

2016-08-05T16:29:09Z

←Older revision		Revision as of 16:29, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain==		==Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain==
	<StructureSection load='3mlh' size='340' side='right' caption='[[3mlh]], [[Resolution\|resolution]] 2.09Å' scene=''>		<StructureSection load='3mlh' size='340' side='right' caption='[[3mlh]], [[Resolution\|resolution]] 2.09Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mlh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Influenza_a_virus~~ Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MLH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mlh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus_(a/mexico/4603/2009(h1n1)) Influenza a virus (a/mexico/4603/2009(h1n1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MLH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~11320~~ Influenza A virus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=644887 Influenza A virus (A/Mexico/4603/2009(H1N1))])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mlh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mlh RCSB], [http://www.ebi.ac.uk/pdbsum/3mlh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mlh OCA], [http://pdbe.org/3mlh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mlh RCSB], [http://www.ebi.ac.uk/pdbsum/3mlh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mlh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3mlh" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Influenza a virus]]
	[[Category: Aguilar-Yanez, J M]]		[[Category: Aguilar-Yanez, J M]]
	[[Category: Alvarez, M M]]		[[Category: Alvarez, M M]]

OCA at 04:00, 25 December 2014

2014-12-25T04:00:14Z

←Older revision		Revision as of 04:00, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mlh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mlh RCSB], [http://www.ebi.ac.uk/pdbsum/3mlh PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mlh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mlh RCSB], [http://www.ebi.ac.uk/pdbsum/3mlh PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/C4RSQ3_9INFA C4RSQ3_9INFA]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.[RuleBase:RU003324][SAAS:SAAS00145386]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 08:38, 18 December 2014

2014-12-18T08:38:37Z

←Older revision		Revision as of 08:38, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3mlh\| PDB=3mlh \| SCENE= }}~~	+	==Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain==
-	===Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain===	+	<StructureSection load='3mlh' size='340' side='right' caption='[[3mlh]], [[Resolution\|resolution]] 2.09Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21068239}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3mlh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MLH FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11320 Influenza A virus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mlh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mlh RCSB], [http://www.ebi.ac.uk/pdbsum/3mlh PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The hemagglutinin (HA) surface glycoprotein promotes influenza virus entry and is the key protective antigen in natural immunity and vaccines. The HA protein is a trimeric envelope glycoprotein consisting of a globular receptor-binding domain (HA-RBD) that is inserted into a membrane fusion-mediating stalk domain. Similar to other Class I viral fusion proteins, the fusogenic stalk domain spontaneously refolds into its postfusion conformation when expressed in isolation, consistent with this domain being trapped in a metastable conformation. Using X-ray crystallography, we show that the influenza virus HA-RBD refolds spontaneously into its native, immunogenic structure even when expressed in an unglycosylated form in Escherichia coli. In the 2.10 A structure of the HA-RBD, the receptor-binding pocket is intact and its conformational epitopes are preserved. Along with recombinant HA-RBD being immunogenic and protective in ferrets, the protein binds with specificity to sera from influenza virus-infected patients. Overall, the data provide a structural basis for the rapid production of influenza vaccines in E. coli. From an evolutionary standpoint, the ability of the HA-RBD to refold spontaneously into its native conformation suggests that influenza virus acquired this domain as an insertion into an ancestral membrane-fusion domain. The insertion of independently folding domains into fusogenic stalk domains may be a common feature of Class I viral fusion proteins.

-	~~==About this~~ Structure==	+	The Receptor-Binding Domain of Influenza Virus Hemagglutinin Produced in Escherichia coli Folds into its Native, Immunogenic Structure.,Dubois RM, Aguilar-Yanez JM, Mendoza-Ochoa GI, Oropeza-Almazan Y, Schultz-Cherry S, Alvarez MM, White SW, Russell CJ J Virol. 2010 Nov 10. PMID:21068239<ref>PMID:21068239</ref>
-	~~[[3mlh]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Influenza_a_virus Influenza a virus]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3MLH OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Hemagglutinin\|Hemagglutinin]]		*[[Hemagglutinin\|Hemagglutinin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:021068239<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Influenza a virus]]		[[Category: Influenza a virus]]
-	[[Category: Aguilar-Yanez, J M.]]	+	[[Category: Aguilar-Yanez, J M]]
-	[[Category: Alvarez, M M.]]	+	[[Category: Alvarez, M M]]
-	[[Category: DuBois, R M.]]	+	[[Category: DuBois, R M]]
-	[[Category: Mendoza-Ochoa, G I.]]	+	[[Category: Mendoza-Ochoa, G I]]
-	[[Category: Russell, C J.]]	+	[[Category: Russell, C J]]
-	[[Category: Schultz-Cherry, S.]]	+	[[Category: Schultz-Cherry, S]]
-	[[Category: White, S W.]]	+	[[Category: White, S W]]
	[[Category: Antigen]]		[[Category: Antigen]]
	[[Category: Hemagglutinin]]		[[Category: Hemagglutinin]]

OCA at 10:33, 11 March 2013

2013-03-11T10:33:05Z

←Older revision		Revision as of 10:33, 11 March 2013
Line 1:		Line 1:
-	[[Image:3mlh.png\|left\|200px]]
-
	{{STRUCTURE_3mlh\| PDB=3mlh \| SCENE= }}		{{STRUCTURE_3mlh\| PDB=3mlh \| SCENE= }}
-
	===Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain===		===Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain===
-
	{{ABSTRACT_PUBMED_21068239}}		{{ABSTRACT_PUBMED_21068239}}

OCA at 12:26, 20 October 2012

2012-10-20T12:26:38Z

←Older revision		Revision as of 12:26, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3mlh]] is a 2 chain structure ~~of [[Hemagglutinin]]~~ with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA].	+	[[3mlh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA].

	==See Also==		==See Also==

OCA at 08:43, 26 July 2012

2012-07-26T08:43:48Z

←Older revision		Revision as of 08:43, 26 July 2012
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	[[Image:3mlh.png\|left\|200px]]		[[Image:3mlh.png\|left\|200px]]

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	{{STRUCTURE_3mlh\| PDB=3mlh \| SCENE= }}		{{STRUCTURE_3mlh\| PDB=3mlh \| SCENE= }}

	===Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain===		===Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain===

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	{{ABSTRACT_PUBMED_21068239}}		{{ABSTRACT_PUBMED_21068239}}

	==About this Structure==		==About this Structure==
-	[[3mlh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA].	+	[[3mlh]] is a 2 chain structure of [[Hemagglutinin]] with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA].
		+
		+	==See Also==
		+	*[[Hemagglutinin\|Hemagglutinin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21068239~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021068239</ref><references group="xtra"/>
	[[Category: Influenza a virus]]		[[Category: Influenza a virus]]
	[[Category: Aguilar-Yanez, J M.]]		[[Category: Aguilar-Yanez, J M.]]
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	[[Category: Schultz-Cherry, S.]]		[[Category: Schultz-Cherry, S.]]
	[[Category: White, S W.]]		[[Category: White, S W.]]
		+	[[Category: Antigen]]
		+	[[Category: Hemagglutinin]]
		+	[[Category: Lectin]]
		+	[[Category: Receptor-binding domain]]
		+	[[Category: Viral protein]]

OCA: Protected "3mlh" [edit=sysop:move=sysop]

2011-01-12T05:25:35Z

Protected "3mlh" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:25, 12 January 2011

OCA at 05:25, 12 January 2011

2011-01-12T05:25:33Z

←Older revision		Revision as of 05:25, 12 January 2011
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-	~~{{Seed}}~~	+	[[Image:3mlh.png\|left\|200px]]
-	[[Image:3mlh.~~jpg~~\|left\|200px]]	+

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	==About this Structure==		==About this Structure==
-	~~3MLH~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA].	+	[[3mlh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLH OCA].

	==Reference==		==Reference==
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	[[Category: Schultz-Cherry, S.]]		[[Category: Schultz-Cherry, S.]]
	[[Category: White, S W.]]		[[Category: White, S W.]]
-	[[Category: Antigen]]
-	[[Category: Hemagglutinin]]
-	[[Category: Lectin]]
-	[[Category: Receptor-binding domain]]
-	[[Category: Viral protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 1 11:31:05 2010''