3mtv - Revision history

OCA at 08:31, 20 March 2024

2024-03-20T08:31:53Z

←Older revision		Revision as of 08:31, 20 March 2024
Line 3:		Line 3:
	<StructureSection load='3mtv' size='340' side='right'caption='[[3mtv]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3mtv' size='340' side='right'caption='[[3mtv]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mtv]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Prrsv Prrsv~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3MTV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mtv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Porcine_reproductive_and_respiratory_syndrome_virus Porcine reproductive and respiratory syndrome virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MTV FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3mtv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mtv OCA], [~~http~~://pdbe.org/3mtv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3mtv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3mtv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3mtv ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mtv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mtv OCA], [https://pdbe.org/3mtv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mtv RCSB], [https://www.ebi.ac.uk/pdbsum/3mtv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mtv ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B2ZAB4_PRRSV B2ZAB4_PRRSV]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 16:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mtv ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mtv ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Porcine reproductive and respiratory syndrome virus (PRRSV), a member of the Arteriviridae family of Nidovirales, is the causative agent of porcine reproductive and respiratory syndrome, which results in enormous economic losses in the swine industry. As the second protein encoded by the PRRSV genome, nsp1beta cleaves itself from the downstream nsp2 protein via a C-terminal papain-like cysteine protease (PCP) domain. Although nsp1beta is known to be involved in virulence, its precise role in the process of viral infection remains unclear. In this work, we describe the homodimeric crystal structure of PRRSV nsp1beta in its natural, self-processed form. We show that the architecture of its N-terminal domain (NTD) adopts a fold closely resembling that of several known nucleases and has intrinsic nuclease activity that is strongly activated by manganese ions in vitro. Key features, however, distinguish nsp1beta from characterized nucleases, including the C-terminal PCP domain (which is responsible for the self-release of nsp1beta from nsp2), a linker domain (LKD) that connects the NTD and the PCP domain, and a C-terminal extension (CTE) that binds to and is stabilized by the putative substrate binding site of the PCPbeta domain. Combined with the reported nuclear localization of this protein, these results shed light on the self-processing mode and precise biological function of nsp1beta and thus offer a multitarget template for future drug discovery.
-
-	The crystal structure of porcine reproductive and respiratory syndrome virus nonstructural protein Nsp1beta reveals a novel metal-dependent nuclease.,Xue F, Sun Y, Yan L, Zhao C, Chen J, Bartlam M, Li X, Lou Z, Rao Z J Virol. 2010 Jul;84(13):6461-71. Epub 2010 Apr 21. PMID:20410261<ref>PMID:20410261</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3mtv" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Nonstructural protein 3D structures\|Nonstructural protein 3D structures]]		*[[Nonstructural protein 3D structures\|Nonstructural protein 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Prrsv~~]]	+	[[Category: Porcine reproductive and respiratory syndrome virus]]
-	[[Category: Lou~~, Z Y~~]]	+	[[Category: Lou ZY]]
-	[[Category: Rao~~, Z H~~]]	+	[[Category: Rao ZH]]
-	[[Category: Sun~~, Y N~~]]	+	[[Category: Sun YN]]
-	[[Category: Xue, F]]	+	[[Category: Xue F]]
-	[[Category: Yan~~, L M~~]]	+	[[Category: Yan LM]]
-	[[Category: Zhao, C]]	+	[[Category: Zhao C]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Nsp1]]~~	+
-	~~[[Category: Nuclease]]~~	+
-	~~[[Category: Papain-like cysteine protease~~]]	+

OCA at 08:59, 21 October 2020

2020-10-21T08:59:17Z

←Older revision		Revision as of 08:59, 21 October 2020
Line 1:		Line 1:

	==The Crystal Structure of the PRRSV Nonstructural Protein Nsp1==		==The Crystal Structure of the PRRSV Nonstructural Protein Nsp1==
-	<StructureSection load='3mtv' size='340' side='right' caption='[[3mtv]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='3mtv' size='340' side='right'caption='[[3mtv]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mtv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Prrsv Prrsv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3MTV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mtv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Prrsv Prrsv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3MTV FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3mtv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mtv OCA], [http://pdbe.org/3mtv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mtv RCSB], [http://www.ebi.ac.uk/pdbsum/3mtv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mtv ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3mtv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mtv OCA], [http://pdbe.org/3mtv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mtv RCSB], [http://www.ebi.ac.uk/pdbsum/3mtv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mtv ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 27:

	==See Also==		==See Also==
-	*[[Nonstructural protein\|Nonstructural protein]]	+	*[[Nonstructural protein 3D structures\|Nonstructural protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Prrsv]]		[[Category: Prrsv]]
	[[Category: Lou, Z Y]]		[[Category: Lou, Z Y]]

OCA at 13:04, 16 January 2019

2019-01-16T13:04:38Z

←Older revision		Revision as of 13:04, 16 January 2019
Line 10:		Line 10:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mt/3mtv_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mt/3mtv_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 03:56, 10 December 2016

2016-12-10T03:56:18Z

←Older revision		Revision as of 03:56, 10 December 2016
Line 1:		Line 1:
		+
	==The Crystal Structure of the PRRSV Nonstructural Protein Nsp1==		==The Crystal Structure of the PRRSV Nonstructural Protein Nsp1==
	<StructureSection load='3mtv' size='340' side='right' caption='[[3mtv]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3mtv' size='340' side='right' caption='[[3mtv]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mtv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Porcine_reproductive_and_respiratory_syndrome_virus Porcine reproductive and respiratory syndrome virus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MTV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mtv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Prrsv Prrsv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MTV FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mtv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mtv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mtv RCSB], [http://www.ebi.ac.uk/pdbsum/3mtv PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mtv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mtv OCA], [http://pdbe.org/3mtv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mtv RCSB], [http://www.ebi.ac.uk/pdbsum/3mtv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mtv ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mtv ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 23:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3mtv" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 30:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Porcine reproductive and respiratory syndrome virus~~]]	+	[[Category: Prrsv]]
	[[Category: Lou, Z Y]]		[[Category: Lou, Z Y]]
	[[Category: Rao, Z H]]		[[Category: Rao, Z H]]
Line 41:		Line 43:
	[[Category: Nuclease]]		[[Category: Nuclease]]
	[[Category: Papain-like cysteine protease]]		[[Category: Papain-like cysteine protease]]
-	[[Category: Prrsv]]

OCA at 08:49, 9 December 2014

2014-12-09T08:49:16Z

←Older revision		Revision as of 08:49, 9 December 2014
Line 1:		Line 1:
-	[[~~Image~~:3mtv.~~png\|left~~\|200px]]	+	==The Crystal Structure of the PRRSV Nonstructural Protein Nsp1==
		+	<StructureSection load='3mtv' size='340' side='right' caption='[[3mtv]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3mtv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Porcine_reproductive_and_respiratory_syndrome_virus Porcine reproductive and respiratory syndrome virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MTV FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mtv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mtv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mtv RCSB], [http://www.ebi.ac.uk/pdbsum/3mtv PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mt/3mtv_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Porcine reproductive and respiratory syndrome virus (PRRSV), a member of the Arteriviridae family of Nidovirales, is the causative agent of porcine reproductive and respiratory syndrome, which results in enormous economic losses in the swine industry. As the second protein encoded by the PRRSV genome, nsp1beta cleaves itself from the downstream nsp2 protein via a C-terminal papain-like cysteine protease (PCP) domain. Although nsp1beta is known to be involved in virulence, its precise role in the process of viral infection remains unclear. In this work, we describe the homodimeric crystal structure of PRRSV nsp1beta in its natural, self-processed form. We show that the architecture of its N-terminal domain (NTD) adopts a fold closely resembling that of several known nucleases and has intrinsic nuclease activity that is strongly activated by manganese ions in vitro. Key features, however, distinguish nsp1beta from characterized nucleases, including the C-terminal PCP domain (which is responsible for the self-release of nsp1beta from nsp2), a linker domain (LKD) that connects the NTD and the PCP domain, and a C-terminal extension (CTE) that binds to and is stabilized by the putative substrate binding site of the PCPbeta domain. Combined with the reported nuclear localization of this protein, these results shed light on the self-processing mode and precise biological function of nsp1beta and thus offer a multitarget template for future drug discovery.

-	~~{{STRUCTURE_3mtv\| PDB=3mtv \| SCENE= }}~~	+	The crystal structure of porcine reproductive and respiratory syndrome virus nonstructural protein Nsp1beta reveals a novel metal-dependent nuclease.,Xue F, Sun Y, Yan L, Zhao C, Chen J, Bartlam M, Li X, Lou Z, Rao Z J Virol. 2010 Jul;84(13):6461-71. Epub 2010 Apr 21. PMID:20410261<ref>PMID:20410261</ref>

-	~~===The Crystal Structure~~ of the ~~PRRSV Nonstructural Protein Nsp1===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20410261}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3mtv]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Porcine_reproductive_and_respiratory_syndrome_virus Porcine reproductive and respiratory syndrome virus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA].~~	+

	==See Also==		==See Also==
	*[[Nonstructural protein\|Nonstructural protein]]		*[[Nonstructural protein\|Nonstructural protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020410261<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Porcine reproductive and respiratory syndrome virus]]		[[Category: Porcine reproductive and respiratory syndrome virus]]
-	[[Category: Lou, Z Y.]]	+	[[Category: Lou, Z Y]]
-	[[Category: Rao, Z H.]]	+	[[Category: Rao, Z H]]
-	[[Category: Sun, Y N.]]	+	[[Category: Sun, Y N]]
-	[[Category: Xue, F.]]	+	[[Category: Xue, F]]
-	[[Category: Yan, L M.]]	+	[[Category: Yan, L M]]
-	[[Category: Zhao, C.]]	+	[[Category: Zhao, C]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Nsp1]]		[[Category: Nsp1]]

OCA at 16:18, 20 October 2012

2012-10-20T16:18:18Z

←Older revision		Revision as of 16:18, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3mtv]] is a 1 chain structure ~~of [[Nonstructural protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Porcine_reproductive_and_respiratory_syndrome_virus Porcine reproductive and respiratory syndrome virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA].	+	[[3mtv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Porcine_reproductive_and_respiratory_syndrome_virus Porcine reproductive and respiratory syndrome virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA].

	==See Also==		==See Also==

OCA: Protected "3mtv" [edit=sysop:move=sysop]

2012-07-26T21:14:20Z

Protected "3mtv" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:14, 26 July 2012

OCA at 21:14, 26 July 2012

2012-07-26T21:14:19Z

←Older revision		Revision as of 21:14, 26 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3mtv.png\|left\|200px]]		[[Image:3mtv.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3mtv", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3mtv\| PDB=3mtv \| SCENE= }}		{{STRUCTURE_3mtv\| PDB=3mtv \| SCENE= }}

	===The Crystal Structure of the PRRSV Nonstructural Protein Nsp1===		===The Crystal Structure of the PRRSV Nonstructural Protein Nsp1===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20410261}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20410261 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20410261}}		{{ABSTRACT_PUBMED_20410261}}

	==About this Structure==		==About this Structure==
-	~~3MTV~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Porcine_reproductive_and_respiratory_syndrome_virus Porcine reproductive and respiratory syndrome virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA].	+	[[3mtv]] is a 1 chain structure of [[Nonstructural protein]] with sequence from [http://en.wikipedia.org/wiki/Porcine_reproductive_and_respiratory_syndrome_virus Porcine reproductive and respiratory syndrome virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA].
		+
		+	==See Also==
		+	*[[Nonstructural protein\|Nonstructural protein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20410261~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020410261</ref><references group="xtra"/>
	[[Category: Porcine reproductive and respiratory syndrome virus]]		[[Category: Porcine reproductive and respiratory syndrome virus]]
	[[Category: Lou, Z Y.]]		[[Category: Lou, Z Y.]]
Line 36:		Line 27:
	[[Category: Papain-like cysteine protease]]		[[Category: Papain-like cysteine protease]]
	[[Category: Prrsv]]		[[Category: Prrsv]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 09:51:36 2010''

OCA at 05:45, 21 July 2010

2010-07-21T05:45:10Z

←Older revision		Revision as of 05:45, 21 July 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3mtv.~~jpg~~\|left\|200px]]	+	[[Image:3mtv.png\|left\|200px]]

	<!--		<!--
Line 37:		Line 37:
	[[Category: Prrsv]]		[[Category: Prrsv]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu May 20~~ 09:39:19 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 09:51:36 2010''

OCA at 06:39, 20 May 2010

2010-05-20T06:39:20Z

←Older revision		Revision as of 06:39, 20 May 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3mtv.jpg\|left\|200px]]

-	The ~~entry 3mtv~~ is ~~ON HOLD~~	+	<!--
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		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
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		+	{{STRUCTURE_3mtv\| PDB=3mtv \| SCENE= }}

-	~~Authors: Xue, F., Sun, Y.N., Yan, L.M., Zhao, C., Lou, Z.Y., Rao, Z.H.~~	+	===The Crystal Structure of the PRRSV Nonstructural Protein Nsp1===

-	Description: The Crystal Structure of the PRRSV Nonstructural Protein Nsp1

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed~~ May ~~12 10~~:47:24 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20410261}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20410261 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20410261}}
		+
		+	==About this Structure==
		+	3MTV is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Porcine_reproductive_and_respiratory_syndrome_virus Porcine reproductive and respiratory syndrome virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTV OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20410261</ref><references group="xtra"/>
		+	[[Category: Porcine reproductive and respiratory syndrome virus]]
		+	[[Category: Lou, Z Y.]]
		+	[[Category: Rao, Z H.]]
		+	[[Category: Sun, Y N.]]
		+	[[Category: Xue, F.]]
		+	[[Category: Yan, L M.]]
		+	[[Category: Zhao, C.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Nsp1]]
		+	[[Category: Nuclease]]
		+	[[Category: Papain-like cysteine protease]]
		+	[[Category: Prrsv]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 20 09:39:19 2010''