3nfh - Revision history

OCA at 10:29, 21 February 2024

2024-02-21T10:29:37Z

←Older revision		Revision as of 10:29, 21 February 2024
Line 1:		Line 1:

	==Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)==		==Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)==
-	<StructureSection load='3nfh' size='340' side='right' caption='[[3nfh]], [[Resolution\|resolution]] 2.17Å' scene=''>	+	<StructureSection load='3nfh' size='340' side='right'caption='[[3nfh]], [[Resolution\|resolution]] 2.17Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nfh]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3NFH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nfh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NFH FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[3nff\|3nff]], [[3nfg\|3nfg]], [[3nfi\|3nfi]]</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.17Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">N0880, RPA49, RRN13, YNL248C ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=4932 ATCC 18824])</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nfh OCA], [https://pdbe.org/3nfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nfh RCSB], [https://www.ebi.ac.uk/pdbsum/3nfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nfh ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3nfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nfh OCA], [~~http~~://pdbe.org/3nfh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3nfh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3nfh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3nfh ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/RPA49_YEAST RPA49_YEAST]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. A49 is easily dissociated from the rest of pol A (pol I), producing the form A*, which shows impaired transcriptional activity and increased sensitivity to alpha-amanitin. The function of A49 might be linked to the RNase H activity that was found associated with this subunit.	+	[https://www.uniprot.org/uniprot/RPA49_YEAST RPA49_YEAST] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. A49 is easily dissociated from the rest of pol A (pol I), producing the form A*, which shows impaired transcriptional activity and increased sensitivity to alpha-amanitin. The function of A49 might be linked to the RNase H activity that was found associated with this subunit.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 21:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nfh ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nfh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The eukaryotic RNA polymerases Pol I, II, and III use different promoters to transcribe different classes of genes. Promoter usage relies on initiation factors, including TFIIF and TFIIE, in the case of Pol II. Here, we show that the Pol I-specific subunits A49 and A34.5 form a subcomplex that binds DNA and is related to TFIIF and TFIIE. The N-terminal regions of A49 and A34.5 form a dimerization module that stimulates polymerase-intrinsic RNA cleavage and has a fold that resembles the TFIIF core. The C-terminal region of A49 forms a "tandem winged helix" (tWH) domain that binds DNA with a preference for the upstream promoter nontemplate strand and is predicted in TFIIE. Similar domains are predicted in Pol III-specific subunits. Thus, Pol I/III subunits that have no counterparts in Pol II are evolutionarily related to Pol II initiation factors and may have evolved to mediate promoter specificity and transcription processivity.
-
-	RNA polymerase I contains a TFIIF-related DNA-binding subcomplex.,Geiger SR, Lorenzen K, Schreieck A, Hanecker P, Kostrewa D, Heck AJ, Cramer P Mol Cell. 2010 Aug 27;39(4):583-94. PMID:20797630<ref>PMID:20797630</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3nfh" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[RNA polymerase\|RNA polymerase]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 18824~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~DNA-directed RNA polymerase~~]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: Cramer, P]]	+	[[Category: Cramer P]]
-	[[Category: Geiger~~, S R~~]]	+	[[Category: Geiger SR]]
-	[[Category: Hanecker, P]]	+	[[Category: Hanecker P]]
-	[[Category: Heck~~, A J.R~~]]	+	[[Category: Heck AJR]]
-	[[Category: Kostrewa, D]]	+	[[Category: Kostrewa D]]
-	[[Category: Lorenzen, K]]	+	[[Category: Lorenzen K]]
-	[[Category: Schreieck, A]]	+	[[Category: Schreieck A]]
-	~~[[Category: Dna binding]]~~	+
-	~~[[Category: Dna binding protein]]~~	+
-	~~[[Category: Rna polymerase]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Winged helix~~]]	+

OCA at 12:56, 16 January 2019

2019-01-16T12:56:31Z

←Older revision		Revision as of 12:56, 16 January 2019
Line 15:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nf/3nfh_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nf/3nfh_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:53, 4 August 2016

2016-08-04T16:53:44Z

←Older revision		Revision as of 16:53, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)==		==Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)==
	<StructureSection load='3nfh' size='340' side='right' caption='[[3nfh]], [[Resolution\|resolution]] 2.17Å' scene=''>		<StructureSection load='3nfh' size='340' side='right' caption='[[3nfh]], [[Resolution\|resolution]] 2.17Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nfh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NFH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nfh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NFH FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3nff\|3nff]], [[3nfg\|3nfg]], [[3nfi\|3nfi]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3nff\|3nff]], [[3nfg\|3nfg]], [[3nfi\|3nfi]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">N0880, RPA49, RRN13, YNL248C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ~~Saccharomyces cerevisiae~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">N0880, RPA49, RRN13, YNL248C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nfh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nfh RCSB], [http://www.ebi.ac.uk/pdbsum/3nfh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nfh OCA], [http://pdbe.org/3nfh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nfh RCSB], [http://www.ebi.ac.uk/pdbsum/3nfh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nfh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nfh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3nfh" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 18824]]
	[[Category: DNA-directed RNA polymerase]]		[[Category: DNA-directed RNA polymerase]]
-	[[Category: Saccharomyces cerevisiae]]
	[[Category: Cramer, P]]		[[Category: Cramer, P]]
	[[Category: Geiger, S R]]		[[Category: Geiger, S R]]

OCA at 11:08, 25 December 2014

2014-12-25T11:08:27Z

←Older revision		Revision as of 11:08, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nfh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nfh RCSB], [http://www.ebi.ac.uk/pdbsum/3nfh PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nfh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nfh RCSB], [http://www.ebi.ac.uk/pdbsum/3nfh PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RPA49_YEAST RPA49_YEAST]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. A49 is easily dissociated from the rest of pol A (pol I), producing the form A*, which shows impaired transcriptional activity and increased sensitivity to alpha-amanitin. The function of A49 might be linked to the RNase H activity that was found associated with this subunit.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:36, 9 December 2014

2014-12-09T10:36:24Z

←Older revision		Revision as of 10:36, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3nfh.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)==
		+	<StructureSection load='3nfh' size='340' side='right' caption='[[3nfh]], [[Resolution\|resolution]] 2.17Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3nfh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NFH FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3nff\|3nff]], [[3nfg\|3nfg]], [[3nfi\|3nfi]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">N0880, RPA49, RRN13, YNL248C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nfh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nfh RCSB], [http://www.ebi.ac.uk/pdbsum/3nfh PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nf/3nfh_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The eukaryotic RNA polymerases Pol I, II, and III use different promoters to transcribe different classes of genes. Promoter usage relies on initiation factors, including TFIIF and TFIIE, in the case of Pol II. Here, we show that the Pol I-specific subunits A49 and A34.5 form a subcomplex that binds DNA and is related to TFIIF and TFIIE. The N-terminal regions of A49 and A34.5 form a dimerization module that stimulates polymerase-intrinsic RNA cleavage and has a fold that resembles the TFIIF core. The C-terminal region of A49 forms a "tandem winged helix" (tWH) domain that binds DNA with a preference for the upstream promoter nontemplate strand and is predicted in TFIIE. Similar domains are predicted in Pol III-specific subunits. Thus, Pol I/III subunits that have no counterparts in Pol II are evolutionarily related to Pol II initiation factors and may have evolved to mediate promoter specificity and transcription processivity.

-	~~{{STRUCTURE_3nfh\| PDB=3nfh \| SCENE= }}~~	+	RNA polymerase I contains a TFIIF-related DNA-binding subcomplex.,Geiger SR, Lorenzen K, Schreieck A, Hanecker P, Kostrewa D, Heck AJ, Cramer P Mol Cell. 2010 Aug 27;39(4):583-94. PMID:20797630<ref>PMID:20797630</ref>

-	~~===Crystal structure~~ of ~~tandem winged helix domain of RNA polymerase I subunit A49 (P4)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20797630}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3nfh]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3NFH OCA].~~	+

	==See Also==		==See Also==
	*[[RNA polymerase\|RNA polymerase]]		*[[RNA polymerase\|RNA polymerase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020797630<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: DNA-directed RNA polymerase]]		[[Category: DNA-directed RNA polymerase]]
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Cramer, P.]]	+	[[Category: Cramer, P]]
-	[[Category: Geiger, S R.]]	+	[[Category: Geiger, S R]]
-	[[Category: Hanecker, P.]]	+	[[Category: Hanecker, P]]
-	[[Category: Heck, A J.R.]]	+	[[Category: Heck, A J.R]]
-	[[Category: Kostrewa, D.]]	+	[[Category: Kostrewa, D]]
-	[[Category: Lorenzen, K.]]	+	[[Category: Lorenzen, K]]
-	[[Category: Schreieck, A.]]	+	[[Category: Schreieck, A]]
	[[Category: Dna binding]]		[[Category: Dna binding]]
	[[Category: Dna binding protein]]		[[Category: Dna binding protein]]

OCA at 16:00, 20 October 2012

2012-10-20T16:00:14Z

←Older revision		Revision as of 16:00, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3nfh]] is a 2 chain structure ~~of [[RNA polymerase]]~~ with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFH OCA].	+	[[3nfh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFH OCA].

	==See Also==		==See Also==

OCA: Protected "3nfh" [edit=sysop:move=sysop]

2012-07-26T20:16:39Z

Protected "3nfh" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:16, 26 July 2012

OCA at 20:16, 26 July 2012

2012-07-26T20:16:38Z

←Older revision		Revision as of 20:16, 26 July 2012
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3nfh.png\|left\|200px]]
-	[[Image:3nfh.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3nfh", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3nfh\| PDB=3nfh \| SCENE= }}		{{STRUCTURE_3nfh\| PDB=3nfh \| SCENE= }}

	===Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)===		===Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20797630}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20797630 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20797630}}		{{ABSTRACT_PUBMED_20797630}}

	==About this Structure==		==About this Structure==
-	~~3NFH~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFH OCA].	+	[[3nfh]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFH OCA].
		+
		+	==See Also==
		+	*[[RNA polymerase\|RNA polymerase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20797630~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020797630</ref><references group="xtra"/>
	[[Category: DNA-directed RNA polymerase]]		[[Category: DNA-directed RNA polymerase]]
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
Line 38:		Line 29:
	[[Category: Transcription]]		[[Category: Transcription]]
	[[Category: Winged helix]]		[[Category: Winged helix]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 14:00:30 2010''

OCA at 09:52, 10 September 2010

2010-09-10T09:52:03Z

←Older revision		Revision as of 09:52, 10 September 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3nfh.jpg\|left\|200px]]

-	The ~~entry 3nfh~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3nfh", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3nfh\| PDB=3nfh \| SCENE= }}

-	~~Authors: Geiger, S.R., Lorenzen, K., Schreieck, A., Hanecker, P., Kostrewa, D., Heck, A.J.R., Cramer, P.~~	+	===Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)===

-	Description: Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Aug 4 08~~:48:22 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20797630}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20797630 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20797630}}
		+
		+	==About this Structure==
		+	3NFH is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFH OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20797630</ref><references group="xtra"/>
		+	[[Category: DNA-directed RNA polymerase]]
		+	[[Category: Saccharomyces cerevisiae]]
		+	[[Category: Cramer, P.]]
		+	[[Category: Geiger, S R.]]
		+	[[Category: Hanecker, P.]]
		+	[[Category: Heck, A J.R.]]
		+	[[Category: Kostrewa, D.]]
		+	[[Category: Lorenzen, K.]]
		+	[[Category: Schreieck, A.]]
		+	[[Category: Dna binding]]
		+	[[Category: Dna binding protein]]
		+	[[Category: Rna polymerase]]
		+	[[Category: Transcription]]
		+	[[Category: Winged helix]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 14:00:30 2010''

OCA at 04:41, 4 August 2010

2010-08-04T04:41:23Z

←Older revision		Revision as of 04:41, 4 August 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3nfh is ON HOLD	+	The entry 3nfh is ON HOLD until Paper Publication

-	Authors: Geiger, S.R.	+	Authors: Geiger, S.R., Lorenzen, K., Schreieck, A., Hanecker, P., Kostrewa, D., Heck, A.J.R., Cramer, P.

	Description: Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)		Description: Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 16~~ 08:31:07 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 4 08:48:22 2010''