3nic - Revision history

OCA at 10:30, 21 February 2024

2024-02-21T10:30:04Z

←Older revision		Revision as of 10:30, 21 February 2024
Line 1:		Line 1:

	==DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F==		==DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F==
-	<StructureSection load='3nic' size='340' side='right' caption='[[3nic]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='3nic' size='340' side='right'caption='[[3nic]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nic]] is a 16 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3NIC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nic]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NIC FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mx1\|3mx1]]~~, [[~~3mx4~~\|~~3mx4~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>eco29kIR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~562~~ "~~Bacillus coli~~" ~~Migula 1895])</td~~><~~/tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nic OCA], [https://pdbe.org/3nic PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nic RCSB], [https://www.ebi.ac.uk/pdbsum/3nic PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nic ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3nic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nic OCA], [~~http~~://pdbe.org/3nic PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3nic RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3nic PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3nic ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q46944_ECOLX Q46944_ECOLX]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 20:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nic ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nic ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The GIY-YIG endonuclease family comprises hundreds of diverse proteins and a multitude of functions; none have been visualized bound to DNA. The structure of the GIY-YIG restriction endonuclease R.Eco29kI has been solved both alone and bound to its target site. The protein displays a domain-swapped homodimeric structure with several extended surface loops encircling the DNA. Only three side chains from each protein subunit contact DNA bases, two directly and one via a bridging solvent molecule. Both tyrosine residues within the GIY-YIG motif are positioned in the catalytic center near a putative nucleophilic water; the remainder of the active site resembles the HNH endonuclease family. The structure illustrates how the GIY-YIG scaffold has been adapted for the highly specific recognition of a DNA restriction site, in contrast to nonspecific DNA cleavage by GIY-YIG domains in homing endonucleases or structure-specific cleavage by DNA repair enzymes such as UvrC.
-
-	Folding, DNA Recognition, and Function of GIY-YIG Endonucleases: Crystal Structures of R.Eco29kI.,Mak AN, Lambert AR, Stoddard BL Structure. 2010 Aug 25. PMID:20800503<ref>PMID:20800503</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3nic" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
-	[[Category: ~~Type II site-specific deoxyribonuclease~~]]	+	[[Category: Large Structures]]
-	[[Category: Lambert~~, A R~~]]	+	[[Category: Lambert AR]]
-	[[Category: Mak~~, A N.S~~]]	+	[[Category: Mak ANS]]
-	[[Category: Stoddard~~, B L]]~~	+	[[Category: Stoddard BL]]
-	~~[[Category: Dna-bound]]~~	+
-	~~[[Category: Giy-yig endonuclease]]~~	+
-	~~[[Category: Hydrolase-dna complex]]~~	+
-	~~[[Category: Type ii restriction endonuclease~~]]	+

OCA at 09:54, 30 January 2019

2019-01-30T09:54:37Z

←Older revision		Revision as of 09:54, 30 January 2019
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ni/3nic_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ni/3nic_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 21:19, 5 August 2016

2016-08-05T21:19:47Z

←Older revision		Revision as of 21:19, 5 August 2016
Line 1:		Line 1:
		+
	==DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F==		==DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F==
	<StructureSection load='3nic' size='340' side='right' caption='[[3nic]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3nic' size='340' side='right' caption='[[3nic]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nic]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NIC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nic]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NIC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mx1\|3mx1]], [[3mx4\|3mx4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mx1\|3mx1]], [[3mx4\|3mx4]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">eco29kIR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">eco29kIR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nic OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nic RCSB], [http://www.ebi.ac.uk/pdbsum/3nic PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nic OCA], [http://pdbe.org/3nic PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nic RCSB], [http://www.ebi.ac.uk/pdbsum/3nic PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nic ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 17:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nic ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3nic" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Type II site-specific deoxyribonuclease]]		[[Category: Type II site-specific deoxyribonuclease]]
	[[Category: Lambert, A R]]		[[Category: Lambert, A R]]

OCA at 16:47, 18 December 2014

2014-12-18T16:47:12Z

←Older revision		Revision as of 16:47, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3nic\| PDB=3nic \| SCENE= }}~~	+	==DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F==
-	===DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F===	+	<StructureSection load='3nic' size='340' side='right' caption='[[3nic]], [[Resolution\|resolution]] 2.80Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20800503}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3nic]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NIC FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mx1\|3mx1]], [[3mx4\|3mx4]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">eco29kIR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nic OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nic RCSB], [http://www.ebi.ac.uk/pdbsum/3nic PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ni/3nic_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The GIY-YIG endonuclease family comprises hundreds of diverse proteins and a multitude of functions; none have been visualized bound to DNA. The structure of the GIY-YIG restriction endonuclease R.Eco29kI has been solved both alone and bound to its target site. The protein displays a domain-swapped homodimeric structure with several extended surface loops encircling the DNA. Only three side chains from each protein subunit contact DNA bases, two directly and one via a bridging solvent molecule. Both tyrosine residues within the GIY-YIG motif are positioned in the catalytic center near a putative nucleophilic water; the remainder of the active site resembles the HNH endonuclease family. The structure illustrates how the GIY-YIG scaffold has been adapted for the highly specific recognition of a DNA restriction site, in contrast to nonspecific DNA cleavage by GIY-YIG domains in homing endonucleases or structure-specific cleavage by DNA repair enzymes such as UvrC.

-	~~==About this Structure==~~	+	Folding, DNA Recognition, and Function of GIY-YIG Endonucleases: Crystal Structures of R.Eco29kI.,Mak AN, Lambert AR, Stoddard BL Structure. 2010 Aug 25. PMID:20800503<ref>PMID:20800503</ref>
-	~~[[3nic]] is a 16 chain structure with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3NIC OCA].~~	+

-	~~==Reference==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	<~~ref group="xtra"~~>~~PMID:020800503~~</~~ref~~>~~<ref group~~=~~"xtra">PMID:001579502</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Type II site-specific deoxyribonuclease]]		[[Category: Type II site-specific deoxyribonuclease]]
-	[[Category: Lambert, A R.]]	+	[[Category: Lambert, A R]]
-	[[Category: Mak, A N.S.]]	+	[[Category: Mak, A N.S]]
-	[[Category: Stoddard, B L.]]	+	[[Category: Stoddard, B L]]
	[[Category: Dna-bound]]		[[Category: Dna-bound]]
	[[Category: Giy-yig endonuclease]]		[[Category: Giy-yig endonuclease]]
	[[Category: Hydrolase-dna complex]]		[[Category: Hydrolase-dna complex]]
	[[Category: Type ii restriction endonuclease]]		[[Category: Type ii restriction endonuclease]]

OCA at 11:57, 24 April 2013

2013-04-24T11:57:09Z

←Older revision		Revision as of 11:57, 24 April 2013
Line 1:		Line 1:
-	[[Image:3nic.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3nic", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3nic\| PDB=3nic \| SCENE= }}		{{STRUCTURE_3nic\| PDB=3nic \| SCENE= }}
-
	===DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F===		===DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20800503}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20800503 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20800503}}		{{ABSTRACT_PUBMED_20800503}}

Line 22:		Line 7:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20800503~~</ref><ref group="xtra">PMID:~~1579502~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020800503</ref><ref group="xtra">PMID:001579502</ref><references group="xtra"/><references/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Type II site-specific deoxyribonuclease]]		[[Category: Type II site-specific deoxyribonuclease]]

OCA: Protected "3nic" [edit=sysop:move=sysop]

2011-03-14T21:45:01Z

Protected "3nic" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:45, 14 March 2011

OCA at 21:44, 14 March 2011

2011-03-14T21:44:59Z

←Older revision		Revision as of 21:44, 14 March 2011
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3nic.png\|left\|200px]]		[[Image:3nic.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~3NIC~~ is a 16 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIC OCA].	+	[[3nic]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIC OCA].

	==Reference==		==Reference==
Line 33:		Line 32:
	[[Category: Hydrolase-dna complex]]		[[Category: Hydrolase-dna complex]]
	[[Category: Type ii restriction endonuclease]]		[[Category: Type ii restriction endonuclease]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 27 11:25:56 2010''

OCA at 08:15, 27 October 2010

2010-10-27T08:15:34Z

←Older revision		Revision as of 08:15, 27 October 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3nic.~~jpg~~\|left\|200px]]	+	[[Image:3nic.png\|left\|200px]]

	<!--		<!--
Line 34:		Line 34:
	[[Category: Type ii restriction endonuclease]]		[[Category: Type ii restriction endonuclease]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri Sep 10 14~~:00:52 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 27 11:25:56 2010''

OCA at 09:52, 10 September 2010

2010-09-10T09:52:23Z

←Older revision		Revision as of 09:52, 10 September 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3nic.jpg\|left\|200px]]

-	The ~~entry 3nic~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3nic", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3nic\| PDB=3nic \| SCENE= }}

-	~~Authors: Mak, A.N.S., Lambert, A.~~R.~~, Stoddard, B.L.~~	+	===DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F===

-	Description: DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul~~ 14 16:07:23 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20800503}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20800503 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20800503}}
		+
		+	==About this Structure==
		+	3NIC is a 16 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NIC OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20800503</ref><ref group="xtra">PMID:1579502</ref><references group="xtra"/>
		+	[[Category: Escherichia coli]]
		+	[[Category: Type II site-specific deoxyribonuclease]]
		+	[[Category: Lambert, A R.]]
		+	[[Category: Mak, A N.S.]]
		+	[[Category: Stoddard, B L.]]
		+	[[Category: Dna-bound]]
		+	[[Category: Giy-yig endonuclease]]
		+	[[Category: Hydrolase-dna complex]]
		+	[[Category: Type ii restriction endonuclease]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 14:00:52 2010''

OCA at 12:01, 14 July 2010

2010-07-14T12:01:14Z

←Older revision		Revision as of 12:01, 14 July 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3nic is ON HOLD	+	The entry 3nic is ON HOLD until Paper Publication

	Authors: Mak, A.N.S., Lambert, A.R., Stoddard, B.L.		Authors: Mak, A.N.S., Lambert, A.R., Stoddard, B.L.
Line 7:		Line 7:
	Description: DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F		Description: DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29kI inactive variant Y49F

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 23 08~~:43:46 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 14 16:07:23 2010''