3nk4 - Revision history

OCA at 09:16, 6 September 2023

2023-09-06T09:16:50Z

←Older revision		Revision as of 09:16, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3nk4' size='340' side='right'caption='[[3nk4]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3nk4' size='340' side='right'caption='[[3nk4]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Chick Chick~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NK4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NK4 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=A2G:N-ACETYL~~-2~~-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3d4c\|3d4c]]~~, ~~[[3d4g\|3d4g]], [[3ef7\|3ef7]], [[3nk3\|3nk3]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk4 OCA], [https://pdbe.org/3nk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nk4 RCSB], [https://www.ebi.ac.uk/pdbsum/3nk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nk4 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk4 OCA], [https://pdbe.org/3nk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nk4 RCSB], [https://www.ebi.ac.uk/pdbsum/3nk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nk4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ZP3_CHICK ZP3_CHICK]] Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.<ref>PMID:15115720</ref> <ref>PMID:20970175</ref>	+	[https://www.uniprot.org/uniprot/ZP3_CHICK ZP3_CHICK] Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.<ref>PMID:15115720</ref> <ref>PMID:20970175</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chick~~]]	+	[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Jovine, L]]	+	[[Category: Jovine L]]
-	[[Category: Monne, M]]	+	[[Category: Monne M]]
-	~~[[Category: Biodiversity]]~~	+
-	~~[[Category: Cell adhesion]]~~	+
-	~~[[Category: Core-1]]~~	+
-	~~[[Category: Egg coat]]~~	+
-	~~[[Category: Egg-sperm interaction]]~~	+
-	~~[[Category: Ehp]]~~	+
-	~~[[Category: External hydrophobic patch]]~~	+
-	~~[[Category: Extracellular matrix]]~~	+
-	~~[[Category: Fertilization]]~~	+
-	~~[[Category: Glycoprotein]]~~	+
-	~~[[Category: Ihp]]~~	+
-	~~[[Category: Immunoglobulin-like fold]]~~	+
-	~~[[Category: Infertility]]~~	+
-	~~[[Category: Internal hydrophobic patch]]~~	+
-	~~[[Category: O-linked carbohydrate]]~~	+
-	~~[[Category: Oocyte]]~~	+
-	~~[[Category: Receptor]]~~	+
-	~~[[Category: Secreted]]~~	+
-	~~[[Category: Speciation]]~~	+
-	~~[[Category: Species-specific gamete recognition]]~~	+
-	~~[[Category: Sperm-combining site]]~~	+
-	~~[[Category: T-antigen]]~~	+
-	~~[[Category: Transmembrane]]~~	+
-	~~[[Category: Vitelline envelope]]~~	+
-	~~[[Category: Zona pellucida]]~~	+
-	~~[[Category: Zp domain]]~~	+
-	~~[[Category: Zp module~~]]	+

OCA at 07:03, 12 May 2022

2022-05-12T07:03:57Z

←Older revision		Revision as of 07:03, 12 May 2022
Line 3:		Line 3:
	<StructureSection load='3nk4' size='340' side='right'caption='[[3nk4]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3nk4' size='340' side='right'caption='[[3nk4]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3NK4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NK4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d4c\|3d4c]], [[3d4g\|3d4g]], [[3ef7\|3ef7]], [[3nk3\|3nk3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3d4c\|3d4c]], [[3d4g\|3d4g]], [[3ef7\|3ef7]], [[3nk3\|3nk3]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk4 OCA], [~~http~~://pdbe.org/3nk4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3nk4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3nk4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3nk4 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk4 OCA], [https://pdbe.org/3nk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nk4 RCSB], [https://www.ebi.ac.uk/pdbsum/3nk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nk4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ZP3_CHICK ZP3_CHICK]] Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.<ref>PMID:15115720</ref> <ref>PMID:20970175</ref>	+	[[https://www.uniprot.org/uniprot/ZP3_CHICK ZP3_CHICK]] Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.<ref>PMID:15115720</ref> <ref>PMID:20970175</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 13:47, 25 December 2019

2019-12-25T13:47:56Z

←Older revision		Revision as of 13:47, 25 December 2019
Line 1:		Line 1:

	==Crystal structure of full-length sperm receptor ZP3 at 2.0 A resolution==		==Crystal structure of full-length sperm receptor ZP3 at 2.0 A resolution==
-	<StructureSection load='3nk4' size='340' side='right' caption='[[3nk4]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3nk4' size='340' side='right'caption='[[3nk4]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NK4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NK4 FirstGlance]. <br>
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Chick]]		[[Category: Chick]]
		+	[[Category: Large Structures]]
	[[Category: Jovine, L]]		[[Category: Jovine, L]]
	[[Category: Monne, M]]		[[Category: Monne, M]]

OCA at 19:27, 24 January 2018

2018-01-24T19:27:59Z

←Older revision		Revision as of 19:27, 24 January 2018
Line 25:		Line 25:
	[[Category: Chick]]		[[Category: Chick]]
	[[Category: Jovine, L]]		[[Category: Jovine, L]]
-	[[Category: Monne , M]]	+	[[Category: Monne, M]]
	[[Category: Biodiversity]]		[[Category: Biodiversity]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]

OCA at 14:44, 5 August 2016

2016-08-05T14:44:20Z

←Older revision		Revision as of 14:44, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of full-length sperm receptor ZP3 at 2.0 A resolution==		==Crystal structure of full-length sperm receptor ZP3 at 2.0 A resolution==
	<StructureSection load='3nk4' size='340' side='right' caption='[[3nk4]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3nk4' size='340' side='right' caption='[[3nk4]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Gallus_gallus Gallus gallus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NK4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NK4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d4c\|3d4c]], [[3d4g\|3d4g]], [[3ef7\|3ef7]], [[3nk3\|3nk3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d4c\|3d4c]], [[3d4g\|3d4g]], [[3ef7\|3ef7]], [[3nk3\|3nk3]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nk4 RCSB], [http://www.ebi.ac.uk/pdbsum/3nk4 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk4 OCA], [http://pdbe.org/3nk4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nk4 RCSB], [http://www.ebi.ac.uk/pdbsum/3nk4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nk4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~P79762_CHICK P79762_CHICK~~]] Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.<ref>PMID:15115720</ref> <ref>PMID:20970175</ref>	+	[[http://www.uniprot.org/uniprot/ZP3_CHICK ZP3_CHICK]] Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.<ref>PMID:15115720</ref> <ref>PMID:20970175</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3nk4" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Gallus gallus~~]]	+	[[Category: Chick]]
	[[Category: Jovine, L]]		[[Category: Jovine, L]]
	[[Category: Monne , M]]		[[Category: Monne , M]]

OCA at 03:21, 25 December 2014

2014-12-25T03:21:19Z

←Older revision		Revision as of 03:21, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NK4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NK4 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d4c\|3d4c]], [[3d4g\|3d4g]], [[3ef7\|3ef7]], [[3nk3\|3nk3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d4c\|3d4c]], [[3d4g\|3d4g]], [[3ef7\|3ef7]], [[3nk3\|3nk3]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nk4 RCSB], [http://www.ebi.ac.uk/pdbsum/3nk4 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nk4 RCSB], [http://www.ebi.ac.uk/pdbsum/3nk4 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/P79762_CHICK P79762_CHICK]] Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.<ref>PMID:15115720</ref> <ref>PMID:20970175</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 13:		Line 15:
	Insights into egg coat assembly and egg-sperm interaction from the X-ray structure of full-length ZP3.,Han L, Monne M, Okumura H, Schwend T, Cherry AL, Flot D, Matsuda T, Jovine L Cell. 2010 Oct 29;143(3):404-15. Epub 2010 Oct 21. PMID:20970175<ref>PMID:20970175</ref>		Insights into egg coat assembly and egg-sperm interaction from the X-ray structure of full-length ZP3.,Han L, Monne M, Okumura H, Schwend T, Cherry AL, Flot D, Matsuda T, Jovine L Cell. 2010 Oct 29;143(3):404-15. Epub 2010 Oct 21. PMID:20970175<ref>PMID:20970175</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 20:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
-	[[Category: Jovine, L.]]	+	[[Category: Jovine, L]]
-	[[Category: Monne , M.]]	+	[[Category: Monne , M]]
	[[Category: Biodiversity]]		[[Category: Biodiversity]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]

OCA at 10:38, 28 May 2014

2014-05-28T10:38:52Z

←Older revision		Revision as of 10:38, 28 May 2014
Line 1:		Line 1:
-	[[~~Image:~~3nk4.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of full-length sperm receptor ZP3 at 2.0 A resolution==
		+	<StructureSection load='3nk4' size='340' side='right' caption='[[3nk4]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3nk4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NK4 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d4c\|3d4c]], [[3d4g\|3d4g]], [[3ef7\|3ef7]], [[3nk3\|3nk3]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nk4 RCSB], [http://www.ebi.ac.uk/pdbsum/3nk4 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	ZP3, a major component of the zona pellucida (ZP) matrix coating mammalian eggs, is essential for fertilization by acting as sperm receptor. By retaining a propeptide that contains a polymerization-blocking external hydrophobic patch (EHP), we determined the crystal structure of an avian homolog of ZP3 at 2.0 A resolution. The structure unveils the fold of a complete ZP domain module in a homodimeric arrangement required for secretion and reveals how EHP prevents premature incorporation of ZP3 into the ZP. This suggests mechanisms underlying polymerization and how local structural differences, reflected by alternative disulfide patterns, control the specificity of ZP subunit interaction. Close relative positioning of a conserved O-glycan important for sperm binding and the hypervariable, positively selected C-terminal region of ZP3 suggests a concerted role in the regulation of species-restricted gamete recognition. Alternative conformations of the area around the O-glycan indicate how sperm binding could trigger downstream events via intramolecular signaling.

-	<!--	+	Insights into egg coat assembly and egg-sperm interaction from the X-ray structure of full-length ZP3.,Han L, Monne M, Okumura H, Schwend T, Cherry AL, Flot D, Matsuda T, Jovine L Cell. 2010 Oct 29;143(3):404-15. Epub 2010 Oct 21. PMID:20970175<ref>PMID:20970175</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3nk4"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_3nk4\| PDB=3nk4 \| SCENE= }}~~	+

-	~~===Crystal structure of full-length sperm receptor ZP3 at 2.0 A resolution===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_20970175}}, adds the Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http:~~/~~/www.pubmed.gov)~~, ~~where 20970175 is~~ the ~~PubMed ID number~~.	+	</StructureSection>
-	~~-->~~	+
-	~~{{ABSTRACT_PUBMED_20970175}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3nk4]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA].~~	+
-		+
-	~~==Reference==~~	+
-	<~~ref group="xtra"~~>~~PMID:020970175~~</~~ref~~>~~<ref group~~=~~"xtra">PMID:007418009</ref><ref group~~=~~"xtra">PMID:001313375</ref><ref group~~=~~"xtra">PMID:009780332</ref><ref group~~=~~"xtra">PMID:010103002~~</~~ref~~><~~ref group="xtra">PMID:012021773</ref><ref group="xtra">PMID:015079052</ref><ref group="xtra">PMID:015952882</ref><ref group="xtra">PMID:019052627</ref><references group="xtra"~~/>	+
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Jovine, L.]]		[[Category: Jovine, L.]]

OCA at 05:16, 4 April 2012

2012-04-04T05:16:04Z

←Older revision		Revision as of 05:16, 4 April 2012
Line 22:		Line 22:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20970175~~</ref><ref group="xtra">PMID:~~7418009~~</ref><ref group="xtra">PMID:~~1313375~~</ref><ref group="xtra">PMID:~~9780332~~</ref><ref group="xtra">PMID:~~10103002~~</ref><ref group="xtra">PMID:~~12021773~~</ref><ref group="xtra">PMID:~~15079052~~</ref><ref group="xtra">PMID:~~15952882~~</ref><ref group="xtra">PMID:~~19052627~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020970175</ref><ref group="xtra">PMID:007418009</ref><ref group="xtra">PMID:001313375</ref><ref group="xtra">PMID:009780332</ref><ref group="xtra">PMID:010103002</ref><ref group="xtra">PMID:012021773</ref><ref group="xtra">PMID:015079052</ref><ref group="xtra">PMID:015952882</ref><ref group="xtra">PMID:019052627</ref><references group="xtra"/>
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Jovine, L.]]		[[Category: Jovine, L.]]

OCA: Protected "3nk4" [edit=sysop:move=sysop]

2011-03-14T20:11:14Z

Protected "3nk4" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:11, 14 March 2011

OCA at 20:11, 14 March 2011

2011-03-14T20:11:12Z

←Older revision		Revision as of 20:11, 14 March 2011
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-	{{Seed}}
	[[Image:3nk4.png\|left\|200px]]		[[Image:3nk4.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~3NK4~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA].	+	[[3nk4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK4 OCA].

	==Reference==		==Reference==
Line 54:		Line 53:
	[[Category: Zp domain]]		[[Category: Zp domain]]
	[[Category: Zp module]]		[[Category: Zp module]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 13:20:06 2010''