3nne - Revision history

OCA at 09:17, 6 September 2023

2023-09-06T09:17:58Z

←Older revision		Revision as of 09:17, 6 September 2023
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	==Crystal structure of choline oxidase S101A mutant==		==Crystal structure of choline oxidase S101A mutant==
-	<StructureSection load='3nne' size='340' side='right' caption='[[3nne]], [[Resolution\|resolution]] 2.47Å' scene=''>	+	<StructureSection load='3nne' size='340' side='right'caption='[[3nne]], [[Resolution\|resolution]] 2.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nne]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"achromobacter_globiformis"_(conn_1928)_bergey_et_al._1930 "achromobacter~~ globiformis~~" (conn 1928) bergey et al. 1930~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NNE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3NNE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nne]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NNE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NNE FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.47Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ljp\|3ljp]]~~, [[~~2jbv~~\|~~2jbv~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>codA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1665~~ "~~Achromobacter globiformis~~" ~~(Conn 1928) Bergey et al. 1930])</td~~><~~/tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nne OCA], [https://pdbe.org/3nne PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nne RCSB], [https://www.ebi.ac.uk/pdbsum/3nne PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nne ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/Choline_oxidase Choline oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.17 1.1.3.17]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3nne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nne OCA], [~~http~~://pdbe.org/3nne PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3nne RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3nne PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3nne ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CHOX_ARTGO CHOX_ARTGO]] Catalyzes the two-step oxidative conversion of choline to glycine-betaine with betaine aldehyde as an intermediate. Glycine-betaine accumulates to high levels in the cytoplasm of cells to prevent dehydration and plasmolysis in adverse hyperosmotic environments. Accepts either choline or the reaction intermediate betaine-aldehyde as substrate.<ref>PMID:12795615</ref>	+	[https://www.uniprot.org/uniprot/CHOX_ARTGO CHOX_ARTGO] Catalyzes the two-step oxidative conversion of choline to glycine-betaine with betaine aldehyde as an intermediate. Glycine-betaine accumulates to high levels in the cytoplasm of cells to prevent dehydration and plasmolysis in adverse hyperosmotic environments. Accepts either choline or the reaction intermediate betaine-aldehyde as substrate.<ref>PMID:12795615</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Choline oxidase~~]]	+	[[Category: Arthrobacter globiformis]]
-	[[Category: Finnegan, S]]	+	[[Category: Large Structures]]
-	[[Category: Gadda, G]]	+	[[Category: Finnegan S]]
-	[[Category: Orville~~, A M~~]]	+	[[Category: Gadda G]]
-	[[Category: Wang, Y F]]	+	[[Category: Orville AM]]
-	[[Category: Weber~~, I T~~]]	+	[[Category: Wang Y-F]]
-	[[Category: Yuan, H]]	+	[[Category: Weber IT]]
-	~~[[Category: Choline]]~~	+	[[Category: Yuan H]]
-	~~[[Category: Flavoprotein]]~~	+
-	~~[[Category: Kinetic]]~~	+
-	~~[[Category: Oxidase]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Reductive half-reaction~~]]	+

OCA at 10:20, 30 January 2019

2019-01-30T10:20:29Z

←Older revision		Revision as of 10:20, 30 January 2019
Line 16:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nn/3nne_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nn/3nne_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 19:15, 5 August 2016

2016-08-05T19:15:16Z

←Older revision		Revision as of 19:15, 5 August 2016
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		+
	==Crystal structure of choline oxidase S101A mutant==		==Crystal structure of choline oxidase S101A mutant==
	<StructureSection load='3nne' size='340' side='right' caption='[[3nne]], [[Resolution\|resolution]] 2.47Å' scene=''>		<StructureSection load='3nne' size='340' side='right' caption='[[3nne]], [[Resolution\|resolution]] 2.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nne]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Arthrobacter_globiformis Arthrobacter~~ globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NNE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nne]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_globiformis"_(conn_1928)_bergey_et_al._1930 "achromobacter globiformis" (conn 1928) bergey et al. 1930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NNE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ljp\|3ljp]], [[2jbv\|2jbv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ljp\|3ljp]], [[2jbv\|2jbv]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">codA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1665 ~~Arthrobacter~~ globiformis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">codA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1665 "Achromobacter globiformis" (Conn 1928) Bergey et al. 1930])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Choline_oxidase Choline oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.17 1.1.3.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Choline_oxidase Choline oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.17 1.1.3.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nne OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nne RCSB], [http://www.ebi.ac.uk/pdbsum/3nne PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nne OCA], [http://pdbe.org/3nne PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nne RCSB], [http://www.ebi.ac.uk/pdbsum/3nne PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nne ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~Q7X2H8_ARTGO Q7X2H8_ARTGO~~]] Catalyzes the two-step oxidative conversion of choline to glycine-betaine with betaine aldehyde as an intermediate. Glycine-betaine accumulates to high levels in the cytoplasm of cells to prevent dehydration and plasmolysis in adverse hyperosmotic environments. Accepts either choline or the reaction intermediate betaine-aldehyde as substrate.<ref>PMID:12795615</ref>	+	[[http://www.uniprot.org/uniprot/CHOX_ARTGO CHOX_ARTGO]] Catalyzes the two-step oxidative conversion of choline to glycine-betaine with betaine aldehyde as an intermediate. Glycine-betaine accumulates to high levels in the cytoplasm of cells to prevent dehydration and plasmolysis in adverse hyperosmotic environments. Accepts either choline or the reaction intermediate betaine-aldehyde as substrate.<ref>PMID:12795615</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 20:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nne ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3nne" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 38:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Arthrobacter globiformis]]
	[[Category: Choline oxidase]]		[[Category: Choline oxidase]]
	[[Category: Finnegan, S]]		[[Category: Finnegan, S]]

OCA at 21:14, 25 December 2014

2014-12-25T21:14:40Z

←Older revision		Revision as of 21:14, 25 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nne OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nne RCSB], [http://www.ebi.ac.uk/pdbsum/3nne PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nne OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nne RCSB], [http://www.ebi.ac.uk/pdbsum/3nne PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/Q7X2H8_ARTGO Q7X2H8_ARTGO]] Catalyzes the two-step oxidative conversion of choline to glycine-betaine with betaine aldehyde as an intermediate. Glycine-betaine accumulates to high levels in the cytoplasm of cells to prevent dehydration and plasmolysis in adverse hyperosmotic environments. Accepts either choline or the reaction intermediate betaine-aldehyde as substrate.<ref>PMID:12795615</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 12:01, 9 December 2014

2014-12-09T12:01:22Z

←Older revision		Revision as of 12:01, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3nne.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of choline oxidase S101A mutant==
		+	<StructureSection load='3nne' size='340' side='right' caption='[[3nne]], [[Resolution\|resolution]] 2.47Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3nne]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NNE FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ljp\|3ljp]], [[2jbv\|2jbv]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">codA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1665 Arthrobacter globiformis])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Choline_oxidase Choline oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.17 1.1.3.17] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nne OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nne RCSB], [http://www.ebi.ac.uk/pdbsum/3nne PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nn/3nne_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The oxidation of choline catalyzed by choline oxidase includes two reductive half-reactions where FAD is reduced by the alcohol substrate and by an aldehyde intermediate transiently formed in the reaction. Each reductive half-reaction is followed by an oxidative half-reaction where the reduced flavin is oxidized by oxygen. Here, we have used mutagenesis to prepare the Ser101Ala mutant of choline oxidase and have investigated the impact of this mutation on the structural and kinetic properties of the enzyme. The crystallographic structure of the Ser101Ala enzyme indicates that the only differences between the mutant and wild-type enzymes are the lack of a hydroxyl group on residue 101 and a more planar configuration of the flavin in the mutant enzyme. Kinetics established that replacement of Ser101 with alanine yields a mutant enzyme with increased efficiencies in the oxidative half-reactions and decreased efficiencies in the reductive half-reactions. This is accompanied by a significant decrease in the overall rate of turnover with choline. Thus, this mutation has revealed the importance of a specific residue for the optimization of the overall turnover of choline oxidase, which requires fine-tuning of four consecutive half-reactions for the conversion of an alcohol to a carboxylic acid.

-	~~{{STRUCTURE_3nne\| PDB=3nne \| SCENE= }}~~	+	Structural and kinetic studies on the Ser101Ala variant of choline oxidase: Catalysis by compromise.,Finnegan S, Yuan H, Wang YF, Orville AM, Weber IT, Gadda G Arch Biochem Biophys. 2010 Sep 15;501(2):207-213. Epub 2010 Jun 16. PMID:20561507<ref>PMID:20561507</ref>

-	~~===Crystal structure~~ of ~~choline oxidase S101A mutant===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20561507}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3nne]] is a 8 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3NNE OCA].~~	+

	==See Also==		==See Also==
	*[[Choline Oxidase\|Choline Oxidase]]		*[[Choline Oxidase\|Choline Oxidase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020561507<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Arthrobacter globiformis]]		[[Category: Arthrobacter globiformis]]
	[[Category: Choline oxidase]]		[[Category: Choline oxidase]]
-	[[Category: Finnegan, S.]]	+	[[Category: Finnegan, S]]
-	[[Category: Gadda, G.]]	+	[[Category: Gadda, G]]
-	[[Category: Orville, A M.]]	+	[[Category: Orville, A M]]
-	[[Category: Wang, Y F.]]	+	[[Category: Wang, Y F]]
-	[[Category: Weber, I T.]]	+	[[Category: Weber, I T]]
-	[[Category: Yuan, H.]]	+	[[Category: Yuan, H]]
	[[Category: Choline]]		[[Category: Choline]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]

OCA at 21:44, 20 October 2012

2012-10-20T21:44:19Z

←Older revision		Revision as of 21:44, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3nne]] is a 8 chain structure ~~of [[Choline Oxidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NNE OCA].	+	[[3nne]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NNE OCA].

	==See Also==		==See Also==

OCA: Protected "3nne" [edit=sysop:move=sysop]

2012-07-27T14:07:56Z

Protected "3nne" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:07, 27 July 2012

OCA at 14:07, 27 July 2012

2012-07-27T14:07:55Z

←Older revision		Revision as of 14:07, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3nne.png\|left\|200px]]		[[Image:3nne.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3nne", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3nne\| PDB=3nne \| SCENE= }}		{{STRUCTURE_3nne\| PDB=3nne \| SCENE= }}

	===Crystal structure of choline oxidase S101A mutant===		===Crystal structure of choline oxidase S101A mutant===

-
-	<!--
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	{{ABSTRACT_PUBMED_20561507}}		{{ABSTRACT_PUBMED_20561507}}

	==About this Structure==		==About this Structure==
-	~~3NNE~~ is a 8 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NNE OCA].	+	[[3nne]] is a 8 chain structure of [[Choline Oxidase]] with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NNE OCA].
		+
		+	==See Also==
		+	*[[Choline Oxidase\|Choline Oxidase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20561507~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020561507</ref><references group="xtra"/>
	[[Category: Arthrobacter globiformis]]		[[Category: Arthrobacter globiformis]]
	[[Category: Choline oxidase]]		[[Category: Choline oxidase]]
Line 38:		Line 29:
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Reductive half-reaction]]		[[Category: Reductive half-reaction]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:19:40 2010''

OCA at 07:10, 15 September 2010

2010-09-15T07:10:58Z

←Older revision		Revision as of 07:10, 15 September 2010
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	{{Seed}}		{{Seed}}
-	[[Image:3nne.~~jpg~~\|left\|200px]]	+	[[Image:3nne.png\|left\|200px]]

	<!--		<!--
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	[[Category: Reductive half-reaction]]		[[Category: Reductive half-reaction]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jul 28 12~~:43:00 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:19:40 2010''

OCA at 08:36, 28 July 2010

2010-07-28T08:36:17Z

←Older revision		Revision as of 08:36, 28 July 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3nne.jpg\|left\|200px]]

-	The ~~entry 3nne~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3nne", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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		+	{{STRUCTURE_3nne\| PDB=3nne \| SCENE= }}

-	~~Authors: Wang, Y.-F., Finnegan, S., Yuan, H., Orville, A.M., Weber, I.T., Gadda, G.~~	+	===Crystal structure of choline oxidase S101A mutant===

-	Description: Crystal structure of choline oxidase S101A mutant

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 30 13~~:37:33 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20561507}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20561507 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20561507}}
		+
		+	==About this Structure==
		+	3NNE is a 8 chains structure with sequences from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NNE OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20561507</ref><references group="xtra"/>
		+	[[Category: Arthrobacter globiformis]]
		+	[[Category: Choline oxidase]]
		+	[[Category: Finnegan, S.]]
		+	[[Category: Gadda, G.]]
		+	[[Category: Orville, A M.]]
		+	[[Category: Wang, Y F.]]
		+	[[Category: Weber, I T.]]
		+	[[Category: Yuan, H.]]
		+	[[Category: Choline]]
		+	[[Category: Flavoprotein]]
		+	[[Category: Kinetic]]
		+	[[Category: Oxidase]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Reductive half-reaction]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:43:00 2010''